Amyloid Beta-Related Angiitis-A Case Report and Comprehensive Review of Literature of 94 Cases

Seminars in Arthritis and Rheumatism

Volumn 44, Issue 1, 2014, Pages 86-92

  Danve, Abhijeet ^a   Grafe, Marjorie ^b   Deodhar, Atul ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Amyloid Beta Related Angiitis; Cerebral amyloid angiopathy; Inflammatory cerebral amyloid angiopathy; Primary CNS vasculitis; Vasculitis

Indexed keywords

AMYLOID BETA PROTEIN; APOLIPOPROTEIN E4; GADOLINIUM;

ADULT; AGED; AMYLOID BETA RELATED ANGIITIS; AUTOIMMUNE DISEASE; BRAIN BIOPSY; BRAIN VASCULITIS; CAUCASIAN; CENTRAL NERVOUS SYSTEM; CLINICAL FEATURE; COGNITIVE DEFECT; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DEMENTIA; DIAGNOSTIC IMAGING; DIFFERENTIAL DIAGNOSIS; FEMALE; GENOTYPE; GRANULOMATOUS VASCULITIS; HEADACHE; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC DISEASE; NUCLEAR MAGNETIC RESONANCE IMAGING; PREVALENCE; PRIORITY JOURNAL; RELAPSE; REVIEW; SEIZURE; SUSCEPTIBILITY WEIGHTED IMAGING; VASCULAR AMYLOIDOSIS; VASCULITIS; VERY ELDERLY; BRAIN; CASE REPORT; COMPLICATION; MIDDLE AGED; PATHOLOGY;

ADULT; AGED; AGED, 80 AND OVER; BRAIN; CEREBRAL AMYLOID ANGIOPATHY; FEMALE; HUMANS; MALE; MIDDLE AGED; VASCULITIS;

EID: 84905222946     PISSN: 00490172     EISSN: 1532866X     Source Type: Journal    
DOI: 10.1016/j.semarthrit.2014.02.001     Document Type: Review

References (49)

1. Pepys M.B. Amyloidosis. Annu Rev Med 2006, 57:223-241.
2. Hawkins Philip N. Amyloidosis Marc Hochberg's text book for rheumatology [chapter 16].
3. Mehndiratta P., Manjila S., Ostergard T., Eisele S., Cohen M.L., Sila C., et al. Cerebral amyloid angiopathy-associated intracerebral hemorrhage: pathology and management. Neurosurg Focus 2012, 32:E7.
4. Greenberg S.M., Vonsattel J.P., Stakes J.W., Gruber M., Finklestein SP. The clinical spectrum of cerebral amyloid angiopathy: presentations without lobar hemorrhage. Neurology 1993, 43:2073-2079.
5. Salvarani C., Brown R.D., Calamia K.T., Christianson T.J., Huston J, Meschia JF, et al. Primary central nervous system vasculitis: comparison of patients with and without cerebral amyloid angiopathy. Rheumatology (Oxford) 2008, 47:1671-1677.
6. Amick A., Joseph J., Silvestri N., Selim M. Amyloid-beta-related angiitis: a rare cause of recurrent transient neurological symptoms. Nat Clin Pract Neurol 2008, 4:279-283.
7. Chung K.K., Anderson N.E., Hutchinson D., Synek B., Barber PA. Cerebral amyloid angiopathy related inflammation: three case reports and a review. J Neurol Neurosurg Psychiatry 2011, 82:20-26.
8. Szpak G.M., Lewandowska E., Sliwinska A., Stepień T., Tarka S., Mendel T., et al. Inflammatory cerebral amyloid angiopathy: the overlap of perivascular (PAN-like) with vasculitic (Aβ-related angiitis) form: an autopsy case. Folia Neuropathol 2011, 49:335-347.
9. Scolding N.J., Joseph F., Kirby P.A., Mazanti I., Gray F., Mikol J., et al. Abeta-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy. Brain 2005, 128:500-515.
10. Schwab P., Lidov H.G., Schwartz R.B., Anderson RJ., et al. Cerebral amyloid angiopathy associated with primary angiitis of the central nervous system: report of 2 cases and review of the literature. Arthritis Rheum 2003, 49:421-427.
11. Mandybur T.I. Cerebral amyloid angiopathy: possible relationship to rheumatoid vasculitis. Neurology 1979, 29:1336-1340.
12. Kinnecom C., Lev M.H., Wendell L., Smith E.E., Rosand J., Frosch M.P., et al. Course of cerebral amyloid angiopathy related inflammation. Neurology 2007, 68:1411-1416.
13. DiFrancesco J.C., Brioschi M., Brighina L., Ruffmann C., Saracchi E., Costantino G., et al. Anti-Aβ autoantibodies in the CSF of a patient with CAA-related inflammation: a case report. Neurology 2011, 76:842-844.
14. Weiss S.A., Pisapia D., Mayer S.A., Willey J.Z., Lee K. Amyloid β-related angiitis causing coma responsive to immunosuppression. Case Rep Pathol 2012, 10.1155/2012/678746.
15. Melzer N., Harder A., Gross C.C., Wolfer J., Stummer W., Niederstadt T., et al. CD4(+) T cells predominate in cerebrospinal fluid and leptomeningeal and parenchymal infiltrates in cerebral amyloid β-related angiitis. Arch Neurol 2012, 69:773-777.
16. Bernstein R.A., Gibbs M., Hunt Batjer H. Clinical diagnosis and successful treatment of inflammatory cerebral amyloid angiopathy. Neurocrit Care 2011, 14:453-455.
17. Fountain N.B., Eberhard D.A. Primary angiitis of the central nervous system associated with cerebral amyloid angiopathy: report of two cases and review of the literature. Neurology 1996, 46:190-197.
18. Harkness K.A., Coles A., Pohl U., Xuereb J.H., Baron J.C., Lennox G.G. Rapidly reversible dementia in cerebral amyloid inflammatory vasculopathy. Eur J Neurol 2004, 11:59-62.
19. Streichenberger N., Girard-Madoux P., Verejan I., Pialat J., Vital C., Kopp N. Giant cell angiitis of the central nervous system with amyloid angiopathy. A case report and review of the literature. Clin Exp Pathol 1999, 47:311-317.
20. Wong S.H., Robbins P.D., Knuckey N.W., Kermode AG. Cerebral amyloid angiopathy presenting with vasculitic pathology. J Clin Neurosci 2006, 13:291-294.
21. Kurian M., Burkhardt K., Assal F., Kövari E., Horvath J. Amyloid plaques and intraneuronal tau inclusions in A-beta-related angiitis (ABRA). Neuropathol Appl Neurobiol 2012, 38:391-394.
22. Wengert O., Harms L., Siebert E. Cerebral amyloid angiopathy-related inflammation: a treatable cause of rapidly-progressive dementia. J Neuropsychiatry Clin Neurosci 2012, 24:E1-E2.
23. Brotman D.J., Eberhart C.G., Burger P.C., McArthur J.C., Hellmann DB. Primary angiitis of the central nervous system and Alzheimer's disease: clinically and pathologically evident in a single patient. J Rheumatol 2000, 27:2935-2937.
24. Fountain N.B., Lopes M.B. Control of primary angiitis of the CNS associated with cerebral amyloid angiopathy by cyclophosphamide alone. Neurology 1999, 52:660-662.
25. Luppe S., Betmouni S., Scolding N., Wilkins A. Cerebral amyloid angiopathy related vasculitis: successful treatment with azathioprine. J Neurol 2010, 257:2103-2105.
26. Yamada M., Naiki H. Cerebral amyloid angiopathy. Prog Mol Biol Transl Sci 2012, 107:41-78.
27. Attems J., Lauda F., Jellinger K.A. Unexpectedly low prevalence of intracerebral hemorrhages in sporadic cerebral amyloid angiopathy: an autopsy study. J Neurol 2008, 255:70-76.
28. Weller R.O., Massey A., Newman T.A., Hutchings M., Kuo Y.M., Roher AE. Cerebral amyloid angiopathy: amyloid b accumulates in putative interstitial fluid drainage pathways in Alzheimer's disease. Am J Pathol 1998, 153:725-733.
29. Herzig M.C., Van Nostrand W.E., Jucker M. Mechanism of cerebral b-amyloid angiopathy: murine and cellular models. Brain Pathol 2006, 16:40-54.
30. Bell R.D., Sagare A.P., Friedman A.E., Bedi G.S., Holtzman D.M., Deane R., et al. Transport pathways for clearance of human Alzheimer's amyloid b-peptide and apolipoproteins E and J in the mouse central nervous system. J Cereb Blood Flow Metab 2007, 27:909-918.
31. Eng J.A., Frosch M.P., Choi K., Rebeck G.W., Greenberg SM. Clinical manifestations of cerebral amyloid angiopathy-related inflammation. Ann Neurol 2004, 55:250-256.
32. Ginsberg L., Geddes J., Valentine A. Amyloid angiopathy and granulomatous angiitis of the central nervous system: a case responding to corticosteroid treatment. J Neurol 1988, 235:438-440.
33. Marotti J.D., Savitz S.I., Kim W.K., Williams K., Caplan L.R., Joseph JT. Cerebral amyloid angiitis processing to generalized angiitis and leucoencephalitis. Neuropathol Appl Neurobiol 2007, 33:475-479.
34. Murphy M.N., Sima A.A. Cerebral amyloid angiopathy associated with giant cell arteritis: a case report. Stroke 1985, 16:514-517.
35. Greenberg S.M., Rapalino O., Frosch M.P. Case records of the Massachusetts General Hospital. Case 22-2010. An 87-year-old woman with dementia and a seizure. N Engl J Med 2010, 363:373-381.
36. Orgogozo J.M., Gilman S., Dartigues J.F., Laurent B., Puel M., Kirby L.C., et al. Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization. Neurology 2003, 61:46-54.
37. Nicoll J.A., Wilkinson D., Holmes C., Steart P., Markham H., Weller R.O. Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report. Nat Med 2003, 9:448-452.
38. Salloway S., Sperling R., Gilman S., Fox N.C., Blennow K., Raskind M. A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease. Neurology 2009, 73:2061-2070.
39. Sugihara S., Ogawa A., Nakazato Y., Yamaguchi H. Cerebral beta amyloid deposition in patients with malignant neoplasms: its prevalence with aging and effects of radiation therapy on vascular amyloid. Acta Neuropathol 1995, 90:135-141.
40. Kloppenborg R.P., Richard E., Sprengers M.E., Troost D., Eikelenboom P., Nederkoorn PJ. Steroid responsive encephalopathy in cerebral amyloid angiopathy: a case report and review of evidence for immunosuppressive treatment. J Neuroinflammation 2010, 7:18.
41. Omisade A., Rigby H., Easton A., Phillips S.J., Carter S.L. Longitudinal neuropsychological findings in amyloid beta-related angiitis (AβRA): a case report. Clin Neuropsychol 2013, 27:300-312.
42. Ghavanini A.A., Munoz D.G. Primary cerebral angiitis associated with amyloid angiopathy. Arch Neurol 2011, 68:1202-1203.
43. Sakai K., Hayashi S., Sanpei K., Yamada M., Takahashi H. Multiple cerebral infarcts with a few vasculitic lesions in the chronic stage of cerebral amyloid angiopathy-related inflammation. Neuropathology 2012, 32:551-556.
44. Rigby H., Easton A., Bhan V. Amyloid β-related angiitis of the central nervous system: report of 3 cases. Can J Neurol Sci 2011, 38:626-630.
45. Hermann D.M., Keyvani K., van de Nes J., Weimar C., Wiltfang J., Nitsch R.M., Szodorai A. Brain-reactive β-amyloid antibodies in primary CNS angiitis with cerebral amyloid angiopathy. Neurology 2011, 77:503-505.
46. Makol A., Parisi J.E., Petty G.W., Watson R.E., Warrington K.J. A 60-year-old woman with headache, confusion, and hallucinations. Arthritis Care Res 2011, 63:1486-1494.
47. Sakaguchi H., Ueda A., Kosaka T., Yamashita S., Kimura E., Yamashita T., et al. Cerebral amyloid angiopathy-related inflammation presenting with steroid-responsive higher brain dysfunction: case report and review of the literature. J Neuroinflammation 2011, 8:116.
48. Tschampa H.J., Niehusmann P., Marek M., Mueller C.A., Kuchelmeister K., Urbach H. MRI in amyloid beta-related brain angiitis. Neurology 2009, 73:247.
49. Iwanaga T., Kaneko N., Nishimura H., Kimura K. Cerebral amyloid angiopathy-related leukodystrophy: a case report. Rinsho Shinkeigaku 2012, 52:585-588.