Concurrent loss of co-stimulatory molecules and functional cytokine secretion attributes leads to proliferative senescence of CD8+ T cells in HIV/TB co-infection

Cellular Immunology

Volumn 297, Issue 1, 2015, Pages 19-32

  Saeidi, Alireza ^a   Chong, Yee K ^a   Yong, Yean K ^a   Tan, Hong Y ^a   Barathan, Muttiah ^a   Rajarajeswaran, Jayakumar ^a   Sabet, Negar S ^b   Sekaran, Shamala D ^a   Ponnampalavanar, Sasheela ^a   Che, Karlhans F ^c   Velu, Vijayakumar ^d   Kamarulzaman, Adeeba ^a   Larsson, Marie ^e   Shankar, Esaki M ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b SEGI UNIVERSITY   (Malaysia)

^c KAROLINSKA INSTITUTE   (Sweden)

^d EMORY UNIVERSITY   (United States)

^e LINKÖPING UNIVERSITY   (Sweden)

Author keywords

Co stimulation; HIV TB co infection; Immune activation; Immunosenescence; T cell activation

Indexed keywords

CD38 ANTIGEN; CD57 ANTIGEN; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 7 RECEPTOR ALPHA; PERFORIN; CD38 PROTEIN, HUMAN; GRANZYME; HLA DR ANTIGEN; MEMBRANE PROTEIN;

ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE COURSE; DISEASE MARKER; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOREACTIVITY; IMMUNOSENESCENCE; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MALE; MIXED INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; T LYMPHOCYTE SUBPOPULATION; TUBERCULOSIS; UPREGULATION; VIREMIA; VIRUS LOAD; BIOSYNTHESIS; CD4 CD8 RATIO; CELL AGING; CELL DIFFERENTIATION; CELL PROLIFERATION; CYTOLOGY; IMMUNOLOGY; LUNG TUBERCULOSIS; LYMPHOCYTE ACTIVATION; METABOLISM; PATHOLOGY;

ADULT; ANTIGENS, CD38; ANTIGENS, CD57; CD4-CD8 RATIO; CD8-POSITIVE T-LYMPHOCYTES; CELL AGING; CELL DIFFERENTIATION; CELL PROLIFERATION; COINFECTION; DISEASE PROGRESSION; FEMALE; GRANZYMES; HIV INFECTIONS; HLA-DR ALPHA-CHAINS; HUMANS; IMMUNOSENESCENCE; INTERFERON-GAMMA; INTERLEUKIN-7 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE ACTIVATION; MALE; MEMBRANE GLYCOPROTEINS; PERFORIN; TUBERCULOSIS, PULMONARY;

EID: 84940449832     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2015.05.005     Document Type: Article

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