Electrochemotherapy as a new approach on pancreatic cancer and on liver metastases

International Journal of Surgery

Volumn 21, Issue S1, 2015, Pages S78-S82

  Tafuto, Salvatore ^a   von Arx, Claudia ^b   De Divitiis, Chiara ^a   Tracey Maura, Claire ^a   Palaia, Raffaele ^a   Albino, Vittorio ^a   Fusco, Roberta ^c   Membrini, Massimo ^a   Petrillo, Antonella ^c   Granata, Vincenza ^c   Izzo, Francesco ^a  

^a NCI Fondazione G Pascale ^*  (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Electrochemotherapy; Electroporation; Liver metastasis; Neuroendocrine tumor; Pancreatic cancer

Indexed keywords

ANTINEOPLASTIC AGENT;

ARTICLE; CLINICAL EFFECTIVENESS; ELECTROCHEMOTHERAPY; ELECTROPORATION; HUMAN; LIVER METASTASIS; NONHUMAN; PANCREAS CANCER; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PRIORITY JOURNAL; PULSE GENERATOR; SKIN NODULE; SUBCUTANEOUS NODULE; LIVER NEOPLASMS; PANCREATIC NEOPLASMS; PROCEDURES; SECONDARY; TREATMENT OUTCOME;

ANTINEOPLASTIC AGENTS; ELECTROCHEMOTHERAPY; HUMANS; LIVER NEOPLASMS; PANCREATIC NEOPLASMS; TREATMENT OUTCOME;

EID: 84940448851     PISSN: 17439191     EISSN: 17439159     Source Type: Journal    
DOI: 10.1016/j.ijsu.2015.04.095     Document Type: Article

References (27)

1. Gehl J. Electroporation: theory and methods, prospectives for drug delivery, gene therapy and research. Acta Physiol. Scand. 2003, 177:437-447. 10.1046/j.1365-201X.2003.01093.x.
2. Orlowski S., Belehradek J., Paoletti C., Mir L.M. Transient electropermeabilization of cells in culture. Increase in the cytotoxicity of anticancer drugs. Biochem. Pharmacol. 1988, 37:4724-4733. 10.1016/0006-2952[88]90344-9.
3. Jaroszeski M.J., Dang V., Pottinger C., Hickey J., Gilbert R., Heller R. Toxicity of anticancer agents mediated by electroporation in vitro. Anticancer Drugs 2000, 11:201-208. 10.1097/00001813-200003000-00008.
4. Skovsgaard T., Mir L.M. Enhancement of cytotoxicity by electropermeabilization: an improved method for screening drugs. Anticancer Drugs 1998, 9:319-325. 10.1097/00001813-199804000-00005.
5. Sersa G., Cemazar M., Miklavcic D. Antitumor effectiveness of electrochemotherapy with cis-diamminedichloroplatinum[II] in mice. Cancer Res. 1995, 55:3450-3455.
6. Kambe M., Arita D., Kikuohi H., Funato T., Tezuka F., Gamo M., et al. Enhancing the effect of anticancer drugs against the colorectal cancer cell line with electroporation. Tahoku J. Exp. Med. 1996, 180:161-171. 10.1620/tjem.180.161.
7. Kuriyama S., Matsumoto M., Mitoro A., Tsujinoue H., Nakatami T., Fukui H., et al. Electrochemotherapy for colorectal cancer with commonly used chemotherapeutic agents in a mouse model. Dig. Dis. Sci. 2000, 45:1568-1577. 10.1023/A: 1005565027969.
8. Sersa G., Stabuc B., Cemazar M., Jancar B., Miklavcic D., Rudolf Z. Electrochemotherapy with cisplatin: potentiation of local cisplatin antitumour effectiveness by application of electric pulses in cancer patients. Eur. J. Cancer 1998, 34:1213-1218. 10.1016/S0959-8049[98]00025-2.
9. Cemazar M., Sersa G., Miklavcic D. Electrochemotherapy with cisplatin in the treatment of tumor cells resistant to cisplatin. Anticancer Res. 1998, 18:4463-4466.
10. Sersa G., Cemazar M., Rudolf Z. Electrochemotherapy: advantages and drawbacks in treatment of cancer patients. Cancer Ther. 2003, 1:133-142.
11. Savoia P., Fava P., Nardò T., Osella-Abate S., Quaglino P., Bernengo M.G. Skin metastases of malignant melanoma: a clinical and prognostic survey. Melanoma Res. 2009, 19:321-326. 10.1097/CMR.0b013e32832ac775.
12. Quaglino P., Mortera C., Osella-Abate S., Barberis M., Illengo M., Rissone M., et al. Electrochemotherapy with intravenous bleomycin in the local treat- ment of skin melanoma metastases. Ann. Surg. Oncol. 2008, 15:2215-2222. 10.1245/s10434-008-9976-0.
13. Campana L.G., Mocellin S., Basso M., Puccetti O., De Salvo G.L., Chiarion-Sileni V., et al. Bleomycin-based electrochemotherapy: clinical outcome from a sin- gle institution's experience with 52 patients. Ann. Surg. Oncol. 2009, 16:191-199. 10.1245/s10434-008-0204-8.
14. Kaehler K.C., Egberts F., Hauschild A. Electrochemotherapy in symptomatic melanoma skin metastases: intraindividual comparison with conventional surgery. Dermatol. Surg. 2010, 36:1200-1202. 10.1111/j.1524-4725.2010.01608.x.
15. Caracò C., Mozzillo N., Marone U., Simeone E., Benedetto L., Di Monta G., et al. Long-lasting response to electrochemotherapy in melanoma patients with cutaneous metastasis. BMC Cancer 2013, 13:564. 10.1186/1471-2407-13-564.
16. Curatolo P., Quaglino P., Marenco F., Mancini M., Nardò T., Mortera C., et al. Electrochemotherapy in the treatment of Kaposi sarcoma cutaneous lesions: a two-center prospective phase II trial. Ann. Surg. Oncol. 2011, 19(1):192-198. 10.1245/s10434-011-1860-7.
17. Latini A., Bonadies A., Trento E., Bultrini S., Cota C., Solivetti F.M., et al. Effective treatment of Kaposi's sarcoma by electrochemotherapy and intravenous bleomycin administration. Dermatol. Ther. 2012, 25(2):214-218. 10.1111/j.1529-8019.2012.01437.X.
18. Di Monta G., Caracò C., Benedetto L., La Padula S., Marone U., Tornesello M.L., et al. Electrochemotherapy as "new standard of care" treatment for cutaneous Kaposi's sarcoma. Eur. J. Surg. Oncol. 2014, 40(1):61-66. 10.1016/j.ejso.2013.09.002.
19. Landström F.J., Nilsson C.O., Reizenstein J.A., Nordqvist K., Adamsson G.B., Löfgren A.L. Electroporation therapy for T1 and T2 oral tongue cancer. Acta Otolaryngol. 2011, 131(6):660-664. 10.3109/00016489.2010.541937.
20. Gargiulo M., Papa A., Capasso P., Moio M., Cubicciotti E., Parascandolo S. Electrochemotherapy for non-melanoma head and neck cancers: clinical outcomes in 25 patients. Ann. Surg. 2012, 255(6):1158-1164. 10.1097/SLA.0b013e31824f68b2.
21. Mali B., Jarm T., Snoj M., Sersa G., Miklavcic D. Antitumor effectiveness of electrochemotherapy: a systematic review and meta-analysis. Eur. J. Surg. Oncol. 2013, 39:4-16. Epub 2012 Sep. 11. 10.1016/j.ejso.2012.08.016.
22. Marty M., Sersa G., Garbay J.R., Gehl J., Collins C.G., Snoj M., et al. Electrochemotherapy - an easy, highly effective and safe treatment of cutaneous and subcutaneous metastases: results of ESOPE [European Standard Operating Procedures of Electrochemotherapy] study. Eur. J. Cancer 2006, 4:3-13. 10.1016/j.ejcsup.2006.08.002.
23. Jaroszeski M.J., Illingworth P., Pottinger C., Hyacinthe M., Heller R. Electrically mediated drug delivery for treating subcutaneous and orthotopic pancreatic adenocarcinoma in a hamster model. Anticancer Res. 1999, 19(2A):989-994.
24. Granata V., Fusco R., Piccirillo M., Palaia R., Lastoria S., Petrillo A., Izzo F. Feasibility and safety of intraoperative electrochemotherapy in locally advanced pancreatic tumor: a preliminary experience. EJI 2014, 12(3).
25. Edhemovic I., Gadzijev E.M., Brecelj E., Miklavcic D., Kos B., Zupanic A. Electrochemotherapy: a new technological approach in treatment of metastases in the liver G. Technol. Cancer Res. Treat. 2011, 10:475-485.
26. Dicitore A., Caraglia M., Gaudenzi G., Arra C., Vitale G. Type I interferon-mediated pathway interacts with peroxisome proliferator activated receptor-γ (PPAR-γ): at the cross-road of pancreatic cancer cell proliferation. Biochim. Biophys. Acta Rev. Cancer 2014, 1845(1):42-52. 10.1016/j.bbcan.2013.11.003.
27. Kingham T.P., Karkar A.M., D'Angelica M.I., Allen P.J., Dematteo R.P., Getra- jdman G.I., et al. Ablation of perivascular hepatic malignant tumors with irreversible electroporation. J. Am. Coll. Surg. 2012, 215(3):379-387. 10.1016/j.jamcollsurg.2012.04.029.