Toxicity of anticancer agents mediated by electroporation in vitro

Anti-Cancer Drugs

Volumn 11, Issue 3, 2000, Pages 201-208

  Jaroszeski, Mark J ^a   Dang, Vu ^a   Pottinger, Carlos ^a   Hickey, Joseph ^b   Gilbert, Richard ^b   Heller, Richard ^a,b  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b University of South Florida   (United States)

Author keywords

Cytotoxicity; Electrochemotherapy; Electropermeabilization; Electroporation; MTT

Indexed keywords

ANCITABINE; ANTINEOPLASTIC AGENT; BLEOMYCIN; BLEOMYCIN SULFATE; CARBOPLATIN; CISPLATIN; CYTARABINE; DOCETAXEL; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; GEMCITABINE; MITOMYCIN C; PACLITAXEL; VINBLASTINE; VINBLASTINE SULFATE; VINCRISTINE; VINCRISTINE SULFATE;

ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG PENETRATION; ELECTROCHEMOTHERAPY; ELECTROPORATION; GENERATOR; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS; BLEOMYCIN; CARBOPLATIN; CELL MEMBRANE PERMEABILITY; CISPLATIN; ELECTROPORATION; FLUOROURACIL; HUMANS; PACLITAXEL; TUMOR CELLS, CULTURED;

EID: 0034100694     PISSN: 09594973     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001813-200003000-00008     Document Type: Article

References (33)

1. 1. Kinosita Jr K, Hibino M, Itoh H, et al. Events of membrane electroporation visualized on a time scale from micro-second to seconds. In: Chang DC, Chassy BM, Saunders JA, Sowers AE, eds. Guide to electroporation and electrofusion. San Diego, CA: Academic Press 1992: 29-46.
2. 2. Teissie, J. Time course of electropermeabilization In: Allen MJ, Cleary SF, Sowers AE, Shillady DD, eds. Charge and field effects in biosystems 3. Boston, MA: Birkhauser 1992: 285-301.
3. 3. Gimsa J, Marszalek P, Loewe U, Tsong TY. Electroporation in rotating electric fields. Bioelectrochem Bioenerg 1992; 29: 81-9.
4. 4. Mir LM, Banoun H, Paoletti C. Introductions of definite amounts of nonpermeant molecules into living cells after electropermeabilizaiton: direct acess to the cytosol. Exp Cell Res 1988; 175: 15-25.
5. 5. Orlowski S, Belehradek Jr J, Paoletti C, Mir LM. Transient electropermeabilization of cells in culture. Biochem Pharmacol 1988; 37: 4727-33.
6. 6. Gehl J, Skovsgaard T, Mir LM. Enhancement of cytotoxicity by electropermeabilization: an improved method for screening drugs. Anti-Cancer Drugs 1998; 9: 319-25.
7. 7. Yabushita H, Yoshikawa K, Hirata M, et al. Effects of electrochemotherapy on CaSki cells derived from a cervical Squamous cell carcinoma. Gynecol Oncol 1997; 65: 297-303.
8. 8. Kambe M, Arita D, Kikuchi H, et al. Enhancing the effect of anticancer drugs against the colorectal cancer cell. Tohoku J Exp Med 1996; 180: 161-71.
9. 9. Cemazar M, Miklavcic D, Sersa G. Intrinsic sensitivity of tumor cells to bleomycin as an indicator of tumor response to electrochemotherapy. Jpn J Cancer Res 1998; 98: 328-33.
10. 10. Cemazar M, Sersa G, Miklavcic D. Electrochemotherapy with cisplatin in treatment of tumor cells resistant to cisplatin. Anticancer Res 1998; 18: 4463-6.
11. 11. Melvik JE, Pettersen EO, Gordon PB, Selgen PO. Increase in cis-dichlorodiammineplatinum(II) cytotoxicity upon reversible electropermeabilization of the plasma membrane in cultured human NHIK 3025 cells. Eur J Cancer Clin Oncol 1986; 22: 1523-30.
12. 12. Sersa G, Cemazar M, Miklavcic D. Antitumor effectiveness of electrochemotherapy with cis-diamminedichloroplatinum(II) in mice. Cancer Res 1995; 55: 3450-5.
13. 13. Neumann E, Schaefer-Ridder M, Wang Y, Hoffschneider PH. Gene transfer into mouse lyoma cells by electropration in high electric fields. EMBO J 1982; 1: 841-5.
14. 14. Zheng Q, Chang DC. High-efficiency gene transfection by in situ electroporation of cultured cells. Biochem. Biophys Acta 1991; 1088: 104-10.
15. 15 Okino M, Morhi H. Effects of a high-voltage electrical impulse and an anticancer drug on in vivo growing tumors. Jpn J Cancer Res 1987; 78: 1319-21.
16. 16. Mir LM, Orlowski S, Belehradek Jr J, Paoletti C. Electrochemotherapy potentiation of antitumour effect of bleomycin by local electric pulses. Eur J Cancer 1991; 27: 68-72.
17. 17. Heller R, Jaroszeski M, Leo-Messina J, et al. Treatment of B16 melanoma with the combination of electroporation and chemotherapy. Bioelectrochem Bioenerg 1995; 36: 83-7.
18. 18. Sersa G, Cemazar M, Miclavcic D, Mir LM. Electrochemotherapy: viariable anti-tumor effect on different tumor models. Bioelectrochem Bioenerg 1994; 35: 23-7.
19. 19. Titomirov AV, Sukharev S, Kistanova E. In vivo electroporation and stable transformatio of skin cells of newborn mice by plasmid DNA. Biochem Biophys Acta 1991; 1088: 131-4.
20. 20. Heller R, Jaroszeski M, Atkin A, et al. In vivo gene electroinjection and expression in rat liver. FEBS Lett 1996; 389: 225-8.
21. 21. Belehradek Jr J, Orlowski S, Ramirez LH, Pron G. Poddevin B, Mir LM. Electropermeabilization of cell in tissues assessed by the qualitative and quantitative electroloading of bleomycin. Biochim Biophys Acta 1994; 1190: 155-63.
22. 111In-bleomycin complex in normal and glioma hearing rats after in vivo electropermeabilization using exponential high-voltage pulses. Bioelectrochem Bioenerg 1998; 46: 241-8.
23. 23 Belehradek M, Domenge C, Luboinnski B, Orlowski S, Belehradek J, Mir LM. Electrochemotherapy, a new antitumor treatment. Cancer 1993; 72: 3694-700.
24. 24 Heller R, Jaroszeski MJ, Reintgen DS, et al. Treatment of cutaneous tumors with electrochemotherapy using intralesional bleomcyin. Cancer 1998; 83: 148-57.
25. 25. Rudolf Z, Stabuc B, Cemazar M, Miklavcic D, Vodovnik L, Sersa G. Electrochemotherapy with bleomycin. The first clinical experience in malignant melanoma patients. Radiol Oncol 1995; 29: 229-35.
26. 26. Heller R, Gilbert R, Jaroszeski MJ. Clinical applications of electrochemotherapy. Adv Drug Del Rev 1999; 35: 119-29.
27. 27. Cemazar M, Miklavcic D, Vodovnik L, et al. Improved therapeutic effect of electrochemotherapy with cisplatin by intratumoral drug administration and changing of electrode orientation for electropermeabilization on EAT tumor model in mice. Radiol Oncol 1995; 29: 121-7.
28. 28. Pendez S, Jaroszeski MJ, Gilbert R, et al. Direct delivery of chemotherapeutic agents for the treatment of hepatomas and sarcomas in rat models. Radiol Oncol 1998; 21: 53-64.
29. 29. Sersa G, Stabuc B, Cemazar M, Jancar B, Miklavcic D, Rudolf Z. Electrochemotherapy with Cisplatin: potentiation of local Cisplatin antitumor effectiveness by application of electric pulses in cancer patients. Eur J Cancer 1998; 34: 1213-8.
30. 30. Becker JL, Papenhausen PR, Widen RH. Cytogenetic, morphologic and oncogene analysis of a cell line derived from a heterologous mixed mullerian tumor of the ovary. In Vitro Cell Dev Biol Animal 1997; 33: 325-31.
31. 31. Pinelli DM, Drake J, Williams MC, Cavanagh D, Becker JL. Hormonal modulation of ishikawa cells during three dimensional growth in vitro. J Soc Gynecol Invest 1998; 5: 217-23.
32. 32. Kinosita Jr K, Ashikawa I, Saita N, et al. Electroporation of cell membrane visualized under a pulsed-laser fluorescence microscope. Biophys J 1988; 53: 1015-9.
33. 33 Teissie J, Blangero C. Direct experimental evidence of the vectorial character of the interaction between electric pulses and cells in cell electronision. Biochem Biophys Acta 1984; 775: 446-8.