Epipolythiodiketopiperazines from the marine derived fungus Dichotomomyces cejpii with NF-κB inhibitory potential

Marine Drugs

Volumn 13, Issue 8, 2015, Pages 4949-4966

  Harms, Henrik ^a   Orlikova, Barbora ^b,c   Ji, Seungwon ^b   Nesaei Mosaferan, Damun ^a   König, Gabriele M ^a   Diederich, Marc ^b  

^a UNIVERSITY OF BONN   (Germany)

^b Seoul National University   (South Korea)

^c LABORATOIRE DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE DU CANCER   (Luxembourg)

Author keywords

Ascomycete; Dichotomomyces; Gliotoxin; Leukemia; NF B

Indexed keywords

5A,6 ANHYDROBISDETHIOBIS(METHYLTHIO)GLIOTOXIN; 6 ACETYLMONODETHIOGLIOTOXIN; ACETYLBISDETHIOBIS(METHYLTHIO)GLIOTOXIN; DNA; EPIPOLYTHIODIKETOPIPERAZINE DERIVATIVE; FUNGAL EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; METHYLTHIO GLIOTOXIN DERIVATIVE; PIPERAZINE DERIVATIVE; POLYKETIDE HEVEADRIDE; PROTEIN P50; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BIOLOGICAL PRODUCT; EPIPOLYTHIODIKETOPIPERAZINE; GLIOTOXIN; POLYKETIDE;

ARTICLE; ASCOMYCETES; CALLYSPONGIA; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DICHOTOMOMYCES CEJPII; DOWN REGULATION; DRUG MECHANISM; DRUG POTENCY; HUMAN; HUMAN CELL; IC50; JURKAT CELL LINE; MYELOID LEUKEMIA CELL LINE; NONHUMAN; PROTEIN BINDING; PROTEIN FUNCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; AQUATIC SPECIES; DRUG EFFECTS; FUNGUS; K-562 CELL LINE; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; METABOLISM; MICROBIOLOGY; SPONGE (PORIFERA); TUMOR CELL LINE;

ASCOMYCOTA; CALLYSPONGIA; DICHOTOMOMYCES; DICHOTOMOMYCES CEJPII; FUNGI;

ANIMALS; AQUATIC ORGANISMS; ASCOMYCOTA; BIOLOGICAL PRODUCTS; CALLYSPONGIA; CELL LINE, TUMOR; DNA; FUNGI; GLIOTOXIN; HUMANS; JURKAT CELLS; K562 CELLS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; NF-KAPPA B; PIPERAZINES; POLYKETIDES; PORIFERA;

EID: 84940416899     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md13084949     Document Type: Article

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