Silaffins in silica biomineralization and biomimetic silica precipitation

Marine Drugs

Volumn 13, Issue 8, 2015, Pages 5297-5333

  Lechner, Carolin C ^a   Becker, Christian F W ^b  

^a EPFL   (Switzerland)

^b UNIVERSITY OF VIENNA   (Austria)

Author keywords

Biomineralization; Diatoms; Posttranslational modifications; Silaffins

Indexed keywords

ANGIOPEPTIN; BIOMIMETIC MATERIAL; BLOCK COPOLYPEPTIDE; LYSOZYME; MESOPOROUS SILICA NANOPARTICLE; POLYALLYLAMINE; POLYARGININE; POLYETHYLENEIMINE; POLYLYSINE; R5 PEPTIDE; SILAFFIN 1A; SILAFFIN 1B; SILAFFIN 2; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; PEPTIDE; SILICON DIOXIDE;

BIOMIMETICS; BIOMINERALIZATION; CHAETOCEROS GRACILIS; CHEMICAL STRUCTURE; CYLINDROTHECA FUSIFORMIS; CYTOKINESIS; DIATOM; ENCAPSULATION; ENZYME IMMOBILIZATION; EUCAMPIA ZODIACUS; IN VITRO STUDY; IN VIVO STUDY; MITOSIS; NANOBIOTECHNOLOGY; NONHUMAN; PRECIPITATION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; RAMAN SPECTROMETRY; REVIEW; THALASSIOSIRA PSEUDONANA; ANIMAL; BIOTECHNOLOGY; CHEMISTRY; DRUG EFFECTS; NANOTECHNOLOGY; PROCEDURES;

BACILLARIOPHYTA;

ANIMALS; BIOMIMETIC MATERIALS; BIOMIMETICS; BIOTECHNOLOGY; DIATOMS; NANOTECHNOLOGY; PEPTIDES; PROTEIN PROCESSING, POST-TRANSLATIONAL; SILICON DIOXIDE;

EID: 84940416356     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md13085297     Document Type: Review

References (229)

1. Wedepohl, K.H. The composition of the continental crust. Geochim. Cosmochim. Acta 1995, 59, 1217-1232.
2. Exley, C. Silicon in life: A bioinorganic solution to bioorganic essentiality. J. Inorg. Biochem. 1998, 69, 139-144.
3. Birchall, J.D. The essentiality of silicon in biology. Chem. Soc. Rev. 1995, 24, 351-357.
4. Nielsen, F.H. Ultratrace Elements in Nutrition. Ann. Rev. Nutr. 1984, 4, 21-41.
5. Schwarz, K.; Milne, D.B. Growth-promoting effects of silicon in rats. Nature 1972, 239, 333-334.
6. Carlisle, E.M. Silicon: An essential element for the chick. Science 1972, 178, 619-621.
7. Hodson, M.J.; White, P.J.; Mead, A.; Broadley, M.R. Phylogenetic variation in the silicon composition of plants. Ann. Bot. 2005, 96, 1027-1046.
8. Mitani, N.; Ma, J.F. Uptake system of silicon in different plant species. J. Exp. Bot. 2005, 56, 1255-1261.
9. Ma, J.F.; Yamaji, N. Functions and transport of silicon in plants. Cell. Mol. Life Sci. 2008, 65, 3049-3057.
10. Raven, J.A. The transport and function of silicon in plants. Biol. Rev. 1983, 58, 179-207.
11. Epstein, E. The anomaly of silicon in plant biology. Proc. Natl. Acad. Sci. USA 1994, 91, 11-17.
12. Epstein, E. Silicon. Annu. Rev. Plant. Physiol. Plant Mol. Biol. 1999, 50, 641-664.
13. Currie, H.A.; Perry, C.C. Silica in Plants: Biological, Biochemical and Chemical Studies. Ann. Bot. 2007, 100, 1383-1389.
14. Ehrlich, H.; Demadis, K.D.; Pokrovsky, O.S.; Koutsoukos, P.G. Modern views on desilicification: Biosilica and abiotic silica dissolution in natural and artificial environments. Chem. Rev. 2010, 110, 4656-4689.
15. Lewin, J.; Reimann, B.E. Silicon and plant growth. Ann. Rev. Plant. Physiol. 1969, 20, 289-304.
16. Norton, T.A.; Melkonian, M.; Andersen, R.A. Algal biodiversity. Phycologia 1996, 35, 353-365.
17. Mann, D.G.; Droop, S.J.M. 3. Biodiversity, biogeography and conservation of diatoms Hydrobiologia 1996, 336, 19-32.
18. Round, F.E.; Crawford, R.M.; Mann, D.G. The Diatoms: Biology and Morphology of the Genera; Cambridge University Press: Cambridge, UK, 1990; p. 747.
19. Kröger, N.; Poulsen, N. Diatoms-From Cell Wall Biogenesis to Nanotechnology. Annu. Rev. Genet. 2008, 42, 83-107.
20. Del Amo, Y.; Brzezinski, M.A. The chemical form of dissolved Si taken up by marine diatoms. J. Phycol. 1999, 35, 1162-1170.
21. Tréguer, P.; Nelson, D.M.; van Bennekom, A.J.; DeMaster, D.J.; Leynaert, A.: Quéquiner, B. The silica balance in the world ocean: A reestimate. Science 1995, 268, 375-379.
22. Martin-Jézéquel, V.; Hildebrand, M.; Brzezinski, M.A. Silicon metabolism in diatoms: Implications for growth. J. Phycol. 2000, 36, 821-840.
23. Hildebrand M.; Volcani B.E.; Gassmann W.; Schroeder, J.I. A gene family of silicon transporters. Nature 1997, 20, 688-689.
24. Thamatrakoln K.; Alverson A.J.; Hildebrand M. Comparative sequence analysis of diatom silicon transporters: Toward a mechanistic model of silicon transport. J. Phycol. 2006, 42, 822-834.
25. Marron, A.O.; Alston, M.J.; Heavens, D.; Akam, M.; Caccamo, M.; Holland, P.W.H.; Walker, G. A family of diatom-like silicon transporters in the siliceous loricate choanoflagellates. Proc. R. Soc. 2013, 280, doi:10.1098/rspb.2012.2543.
26. Simpson, T.L.; Volcani, B.E. Silicon and Siliceous Structures in Biological Systems; Springer-Verlag: New York, NY, USA, 1981.
27. Li, C.W.; Chu, S.; Lee, M. Characterizing the silica deposition vesicle of diatoms. Protoplasma 1989, 151, 158-163.
28. Vrieling, E.G.; Gieskes, W.W.C.; Beelen, T.P.M. Silicon deposition in diatoms: Control by the pH inside the silicon deposition vesicle. J. Phycol. 1999, 35, 548-559.
29. Tesson, B.; Hildebrand, M. Extensive and intimate association of the cytoskeleton with forming silica in diatoms: Control over patterning on the meso-And micro-scale. PLoS ONE 2010, 5, doi:10.1371/journal.pone.0014300.
30. Chiappino, M.L.; Volcani, B.E. Studies on the biochemistry and fine structure of silica shell formation in diatoms. Protoplasma 1977, 93, 205-221.
31. Kröger N.; Wetherbee, R. Pleuralins are involved in theca differentiation in the diatom Cylindrotheca fusiformis. Protist 2000, 151, 263-273.
32. Volcani, B.E. Biochemistry of Silicon and Related Problems; Bendz, G., Lindquist, I., Eds.; Plenum Publishing: New York, NY, USA, 1978; pp. 177-204.
33. Nakajima T.; Volcani, B.E. 3,4-Dihydroxyproline-A new amino acid in diatom cell wall. Science 1969, 164, 1400-1401.
34. Nakajima, T.; Volcani, B.E. -N-Trimethyl-L-hydroxysine phosphate and its nonphosphorylated compound in diatom cell walls. Biochem. Biophys. Res. Commun. 1970, 39, 28-33.
35. Hecky, R.E.; Mopper, K.; Kilham, P.; Degens, T.E. The amino acid and sugar composition of diatom cell-walls. Mar. Biol. 1973, 19, 323-331.
36. Kröger, N.; Bergsdorf, C.; Sumper, M. A new calcium-binding glycoprotein family constitutes a major diatom cell wall component. EMBO J. 1994, 13, 4676-4683.
37. Kröger, N.; Bergsdorf, C.; Sumper, M. Frustulins: Domain conservation in a protein family associated with diatom cell walls. Eur. J. Biochem. 1996, 239, 259-264.
38. Kröger, N.; Lehmann, G.; Rachel, R.; Sumper, M. Characterization of a 200-kDa diatom protein that is specifically associated with a silica-based substructure of the cell wall. Eur. J. Biochem. 1997, 250, 99-105.
39. Van de Poll, W.H.; Vrieling, E.G.; Gieskes, W.W.C. Location and expression of frustulins in the pennate diatoms Cylindrotheca fusiformis, Navicula pelliculosa, and Navicula salinarum (Bacillariophyceae). J. Phycol. 1999, 35, 1044-1053.
40. Bidle, K.D.; Azam, F. Accelerated dissolution of diatom silica by marine bacterial assemblages. Nature 1999, 397, 508-512.
41. Santos, J.; Almeida, S.F.P.; Figueira, E. Cadmium chelation by frustulins: A novel metal tolerance mechanism in Nitzschia palea (Kützing) W. Smith. Ecotoxicology 2013, 22, 166-173.
42. Davis, A.K.; Hildebrand, M.; Palenik, B. A stress-induced protein associated with the girdle band region of the diatom Thalassiosira pseudonana (Bacillariophyta). J. Phycol. 2005, 41, 577-589.
43. Davis, A.K.; Hildebrand, M.; Palenik, B. Gene expression induced by copper stress in the diatom Thalassiosira pseudonana. Eukaryot. Cell 2006, 5, 1157-1168.
44. Hildebrand, M.; Kim, S.; Shi, D.; Scott, K.; Subramaniam, S. 3D imaging of diatoms with ion-Abrasion scanning electron microscopy. J. Struct. Biol. 2009, 166, 316-328.
45. Hildebrand, M.; Holton, G.; Joy, D.C.; Doktycz, M.J.; Allison, D.P. Diverse and conserved nano-And mesoscale structures of diatom silica revealed by atomic force microscopy. J. Microsc. 2009, 235, 172-187.
46. Brunner, E.; Richthammer, P.; Ehrlich, H.; Paasch, S.; Ueberlein, S.; van Pee, K.H. Chitin-based organic networks: An integral part of cell wall biosilica from the diatom Thalassiosira pseudonana. Angew. Chem. Int. Ed. 2009, 48, 9724-9727.
47. Spinde, K.; Kammer, M.; Freyer, K.; Ehrlich, H.; Vournakis, J.N.; Brunner, E. Biomimetic silicification of fibrous chitin from diatoms. Chem. Mater. 2011, 23, 2973-2978.
48. Scheffel, A.; Poulsen, N.; Shian, S.; Kröger, N. Nanopatterned protein microrings from a diatom that direct silica morphogenesis. Proc. Natl. Acad. Sci. USA 2011, 108, 3175-3180.
49. Kröger, N.; Deutzmann, R.; Bergsdorf, C.; Sumper, M. Species-specific polyamines from diatoms control silica morphology. Proc. Natl. Acad. Sci. USA 2000, 97, 14133-14138.
50. Sumper, M.; Brunner, E.; Lehmann, G. Biomineralization in diatoms: Characterization of novel polyamines associated with silica. FEBS Lett. 2005, 579, 3765-3769.
51. Sumper, M.; Lehmann, G. Silica pattern formation in diatoms: Species-specific polyamine biosynthesis. ChemBioChem 2006, 9, 1419-1427.
52. Sumper, M.; Brunner, E. Learning from diatoms: Nature's tools for the production of nanostructured silica. Adv. Funct. Mat. 2006, 16, 17-26.
53. Frigeri, L.G.; Radabaugh, T.R.; Haynes, P.A.; Hildebrand, M. Identification of proteins from a cell wall fraction of the diatom Thalassiosira pseudonana-Insights into silica structure formation. Mol. Cell. Proteomics 2006, 5, 182-193.
54. Sumper, M.; Lorenz, S.; Brunner, E. Biomimetic control of size in the polyamine-directed formation of silica nanospheres. Angew. Chem. Int. Ed. 2003, 42, 5192-5195.
55. Wenzl, S.; Hett, R.; Richthammer P.; Sumper, M. Silacidins: Highly acidic phosphopeptides from diatom shells assist in silica precipitation in vitro. Angew. Chem. Int. Ed. 2008, 47, 1729-1732.
56. Richthammer, P.; Börmel, M.; Brunner, E.; van Pée, K.H. Biomineralization in diatoms: The role of silacidins. ChemBioChem 2011, 12, 1362-1366.
57. Kröger, N.; Deutzmann, R.; Sumper, M. Polycationic peptides from diatom biosilica that direct silica nanosphere formation. Science 1999, 286, 1129-1132.
58. Kröger, N.; Deutzmann, R.; Sumper, M. Silica-precipitating peptides from diatoms. The chemical structure of silaffin-A from Cylindrotheca fusiformis. J. Biol. Chem. 2001, 276, 26066-26070.
59. Kröger, N.; Lorenz, S.; Brunner, E.; Sumper, M. Self-Assembly of highly phosphorylated silaffins and their function in biosilica morphogenesis. Science 2002, 29, 584-586.
60. Senior, L.; Crump, M.P.; Williams, C.; Booth, P.J.; Mann, S.; Perriman, A.W.; Curnow, P. Structure and function of the silicifying peptide R5. J. Mater. Chem. B 2015, 3, 2607-2614.
61. Poulsen, N.; Sumper, M.; Kröger, N. Biosilica formation in diatoms: Characterization of native silaffin-2 and its role in silica morphogenesis. Proc. Natl. Acad. Sci. USA 2003, 100, 12075-12080.
62. Poulsen, N.; Kröger, N. Silica morphogenesis by alternative processing of silaffins in the diatom Thalassiosira pseudonana. J. Biol. Chem. 2004, 279, 42993-42999.
63. Sumper, M.; Hett, R.; Lehmann, G.; Wenzl, S. A code for lysine modifications of a silica biomineralizing silaffin protein. Ang. Chem. Int. Ed. 2007, 46, 8405-8408.
64. Wenzl, S.; Deutzmann, R.; Hett, R.; Hochmuth, E.; Sumper, M. Quaternary ammonium groups in silica-Associated proteins. Angew. Chem. Int. Ed. 2004, 43, 5933-5936.
65. Manurung, A.I.; Pratiwi, A.R.; Syah, D.; Suhartono, M.T. Isolation and characterization of silaffin that catalyze biosilica formation from marine diatom Chaetoceros gracilis. HAYATI J. Biosci. 2007, 14, 119-122.
66. Sumper, M.; Brunner, E. Silica biomineralisation in diatoms: The model organism Thalassiosira pseudonana. ChemBioChem 2008, 9, 1187-1194.
67. Poulsen, N.; Scheffel, A.; Sheppard, V.C.; Chesley, P.M.; Kröger, N. Pentalysine clusters mediate silica targeting of silaffins in Thalassiosira pseudonana. J. Biol. Chem. 2013, 288, 20100-20109.
68. Sheppard, V.; Poulsen, N.; Kröger, N. Characterization of an endoplasmic reticulum-Associated silaffin kinase from the diatom Thalassiosira pseudonana. J. Biol. Chem. 2010, 285, 1166-1176.
69. Iler, R.K. The Chemistry of Silica; Wiley: New York, NY, USA, 1979.
70. Ostwald, W. Studien über die Bildung und Umwandlung fester Körper. Z. Phys. Chem. 1897, 22, 289-330.
71. Mizutani, T.; Nagase, H.; Fujiwara N.; Ogoshi, H. Silicic acid polymerization catalyzed by amines and polyamines. Bull. Chem. Soc. Jpn. 1998, 71, 2017-2022.
72. Coradin, T.; Durupthy, O.; Livage, J. Interactions of amino-containing peptides with sodium silicate and colloidal silica: A biomimetic approach of silicification. Langmuir 2002, 18, 2331-2336.
73. Delak, K.M.; Sahai, N. Amine-catalyzed biomimetic hydrolysis and condensation of organosilicate. Chem. Mater. 2005, 17, 3221-3227.
74. Borowitzka, M.A.; Volcani, B.E. The polymorphic diatom Phaeodactylum tricornutum: Ultrastructure of its morphotypes. J. Phycol. 1978, 14, 10-21.
75. Schmid, A.M.M.; Schulz, D. Wall morphogenesis in diatoms: Deposition of silica by cytoplasmic vesicles. Protoplasma 1979, 100, 267-288.
76. Sumper, M. A phase separation model for the nanopatterning of diatom biosilica. Science 2002, 295, 2430-2433.
77. Brunner, E.; Lutz, K.; Sumper, M. Biomimetic synthesis of silica nanospheres depends on the aggregation and phase separation of polyamines in aqueous solution. Phys. Chem. Chem. Phys. 2004, 6, 854-857.
78. Lutz, K.; Gröger, C.; Sumper, M.; Brunner, E. Biomimetic silica formation: Analysis of the phosphate-induced self-Assembly of polyamines. Phys. Chem. Chem. Phys. 2005, 7, 2812-2815.
79. Bernecker, A.; Wieneke, R.; Riedel, R.; Seibt, M.; Geyer, A.; Steinem, C. Tailored synthetic polyamines for controlled biomimetic silica formation. J. Am. Chem. Soc. 2010, 132, 1023-1031.
80. Kröger, N.; Sumper, M. The biochemistry of silica formation in diatoms. In Biomineralization; Baeuerlein, E., Ed.; Wiley-VCH: Weinheim, Germany, 2000; p. 168.
81. Knecht, M.R.; Wright, D.W. Functional analysis of the biomimetic silica precipitating activity of the R5 peptide from Cylindrotheca fusiformis. Chem. Commun. 2003, 3038-3039.
82. Lechner, C.C.; Becker, C.F.W. A sequence-function analysis of the silica precipitating silaffin R5 peptide. J. Pept. Sci. 2014, 20, 152-158.
83. Lechner, C.C.; Becker, C.F.W. Exploring the effect of native and artificial peptide modifications on silaffin induced silica precipitation. Chem. Sci. 2012, 3, 3500-3504.
84. Berthod, A. Silica: Backbone material of liquid chromatographic column packings. J. Chromatogr. 1991, 549, 1-28.
85. Chaudhry, Q.; Scotter, M.; Blackburn, J.; Ross, B.; Boxall, A.; Castle, L.; Aitken, R.; Watkins, R. Applications and implications of nanotechnologies for the food sector. Food Addit. Contam. 2008, 25, 241-258.
86. Patwardhan, S.V. Biomimetic and bioinspired silica: Recent developments and applications. Chem. Commun. 2011, 47, 7567-7582.
87. Li, Z.; Barnes, J.C.; Bosoy, A.; Stoddart, J.F.; Zink, J.I. Mesoporous silica nanoparticles in biomedical applications. Chem. Soc. Rev. 2012, 41, 2590-2605.
88. United States Environmental Protection Agency. R.E.D. FACTS: Silicon dioxide and Silica Gel; EPA/540/FS-92/173; U.S. Environmental Protection Agency, Office of Prevention, Pesticides and Toxic Substances: Washington, DC, USA, 1991.
89. Pamirsky, I.E.; Golokhvast, K.S. Silaffins of diatoms: From applied biotechnology to biomedicine. Mar. Drugs 2013, 11, 3155-3167.
90. Kresge, C.T.; Leonowicz, M.E.; Roth, W.J.; Vartuli, J.C.; Beck, J.S. Ordered mesoporous molecular sieves synthesized by a liquid-crystal template mechanism. Nature 1992, 359, 710-712.
91. Beck, J.S.; Vartuli, J.C.; Roth, W.J.; Leonowicz, M.E.; Kresge, C.T.; Schmitt, K.D.; Chu, C.T.W.; Olson, D.H.; Sheppard, E.W. A new family of mesoporous molecular sieves prepared with liquid crystal templates. J. Am. Chem. Soc. 1992, 114, 10834-10843.
92. Wan, Y.; Zhao, D. On the controllable soft-templating approach to mesoporous silicates. Chem. Rev. 2007, 107, 2821-2860.
93. Giraldo, L.F.; López, B.L.; Pérez, L.; Urrego, S.; Sierra, L.; Mesa, M. Mesoporous Silica Applications. Macromol. Symp. 2007, 258, 129-141.
94. Vallet-Regi, M.; Ramila, A.; del Real, R.P.; Perez-Pariente, J. A new property of MCM-41: Drug delivery system. J. Chem. Mater. 2001, 13, 308-311.
95. Radu, D.R.; Lai, C.Y.; Jeftinija, K.; Rowe, E.W.; Jeftinija, S.; Lin, V.S.Y. A polyamidoamine dendrimer-capped mesoporous silica nanosphere-based gene transfection reagent. J. Am. Chem. Soc. 2004, 126, 13216-13217.
96. Slowing, I.; Trewyn, B.G.; Lin, V.S.Y. Effect of surface functionalization of MCM-41-type mesoporous silica nanoparticles on the endocytosis by human cancer cells. J. Am. Chem. Soc. 2006, 128, 14792-14793.
97. Trewyn, B.G.; Nieweg, J.A.; Zhao, Y.; Lin, V.S.Y. Biocompatible mesoprous silica nanoparticles with different morphologies for animal cell membrane penetration. Chem. Eng. J. 2008, 137, 23-29.
98. Mortera, R.; Vivero-Escoto, J.; Slowing, I.I.; Garrone, E.; Onida, B.; Lin, V.S. Cell-induced intracellular controlled release of membrane impermeable cysteine from a mesoporous silica nanoparticle-based drug delivery system. Chem. Commun. 2009, 3219-3221.
99. Schlossbauer, A.; Schaffert, D.; Kecht, J.; Wagner, E.; Bein, T. Click chemistry for highdensity biofunctionalization of mesoporous silica. J. Am. Chem. Soc. 2008, 130, 12558-12559.
100. Charnay, C.; Bégu, S.; Tourné-Péteilh, C.; Nicole, L.; Lerner, D.A.; Devoisselle, J.M. Inclusion of ibuprofen in mesoporous templated silica: Drug loading and release property. Eur. J. Pharm. Biopharm. 2004, 57, 533-540.
101. Nieto, A.; Colilla, M.; Balas, F.; Vallet-Regi, M. Surface electrochemistry of mesoporous silicas as a key factor in the design of tailored delivery devices. Langmuir 2010, 26, 5038-5049.
102. Tourne-Peteilh, C.; Lerner D.A.; Charnay, C.; Nicole, L.; Bégu, S.; Devoisselle, J.M. The potential of ordered mesoporous silica for the storage of drugs: The example of a pentapeptide encapsulated in a MSU-Tween 80. ChemPhysChem 2003, 4, 281-286.
103. Slowing, I.I.; Trewyn, B.G.; Lin, V.S.Y. Mesoporous silica nanoparticles for intracellular delivery of membrane-impermeable proteins. J. Am. Chem. Soc. 2007, 129, 8845-8849.
104. Lei, C.; Liu, P.; Chen, B.; Mao, Y.; Engelmann, H.; Shin, Y.; Jaffar, J.; Hellstrom, I.; Liu, J.; Hellstrom, K.E. Local Release of Highly Loaded Antibodies from Functionalized Nanoporous Support for Cancer Immunotherapy. J. Am. Chem. Soc. 2010, 132, 6906-6907.
105. Yang, C.M.; Lin, H.A.; Zibrowius, B.; Spliethoff, B.; Schueth, F.; Liou, S.C.; Chu, M.W.; Chen, C.H. Selective surface functionalization and metal deposition in the micropores of mesoporous silica SBA-15. Chem. Mater. 2007, 19, 3205-3211.
106. Kecht, J.; Schlossbauer, A.; Bein, T. Selective functionalization of the outer and inner surfaces in mesoporous silica nanoparticles. Chem. Mater. 2008, 20, 7207-7214.
107. Doadrio, J.C.; Sousa, E.M.B.; Izquierdo-Barba, I.; Doadrio, A.L.; Perez-Pariente, J.; Vallet-Regi, M. Functionalization of mesoporous materials with long alkyl chains as a strategy for controlling drug delivery pattern. J. Mater. Chem. 2006, 16, 462-466.
108. Popova, M.D.; Szegedi, A.; Kolev, I.N.; Mihaly, J.; Tzanikov, B.S.; Momekov, G.T.; Lambov, N.G.; Yoncheva, K.P. Carboxilic modified spherical mesoporous silica as drug delivery carriers. Int. J. Pharm. 2012, 436, 778-785.
109. Vallet-Regí, M.; Balas, F.; Arcos, D. Mesoporous Materials for Drug Delivery. Angew. Chem. Int. Ed. 2007, 46, 7548-7558.
110. Liong, M.; Lu, J.; Kovochich, M.; Xia, T.; Ruehm, S.G.; Nel, A.E.; Tamanoi F.; Zink, J.I. Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery. ACS Nano 2008, 2, 889-896.
111. Rosenholm, J.M.; Meinander, A.; Peuhu, E.; Niemi, R.; Eriksson, J.E.; Sahlgren, C.; Linden, M. Targeting of porous hybrid silica nanoparticles to cancer cells. ACS Nano 2009, 3, 197-206.
112. Brevet, D.; Gary-Bobo, M.; Raehm, L.; Richeter, S.; Hocine, O.; Amro, K.; Loock, B.; Couleaud, P.; Frochot, C.; Morere, A.; et al. Mannose-targeted mesoporous silica nanoparticles for photodynamic therapy. Chem. Commun. 2009, 1475-1477.
113. Luo, Z.; Cai, K.; Hu, Y.; Zhao, L.; Liu, P.; Duan, L.; Yang, W. Mesoporous silica nanoparticles end-capped with collagen: Redox-responsive nanoreservoirs for targeted drug delivery. Angew. Chem. Int. Ed. 2010, 50, 640-643.
114. Cheng, S.H.; Lee, C.H.; Chen, M.C.; Souris, J.S.; Tseng, F.G.; Yang, C.S.; Mou, C.Y.; Chen, C.T.; Lo, L.W. Trifunctionalization of mesoporous silica nanoparticles for comprehensive cancer theranostics-the trio of imaging, targeting and therapy. J. Mater. Chem. 2010, 20, 6149-6157.
115. Ferris, D.P.; Lu, J.; Gothard, C.; Yanes, R.; Thomas, C.R.; Olsen, J.C.; Stoddart, J.F.; Tamanoi, F.; Zink, J.I. Synthesis of biomolecule-modified mesoporous silica nanoparticles for targeted hydrophobic drug delivery to cancer cells. Small 2011, 7, 1816-1826.
116. Tsai, C.P.; Chen, C.Y.; Hung, Y.; Chang, F.H.; Mou, C.Y. Monoclonal antibody-functionalized mesoporous silica nanoparticles (MSN) for selective targeting breast cancer cells. J. Mater. Chem. 2009, 19, 5737-5743.
117. Cauda, V.; Engelke, H.; Sauer, A.; Arcizet, D.; Braeuchle, C.; Raedler, J.; Bein, T. Colchicine-loaded lipid bilayer-coated 50 nm mesoporous nanoparticles efficiently induce microtubule depolymerization upon cell uptake. Nano Lett. 2010, 10, 2484-2492.
118. Mackowiak, S.A.; Schmidt, A.; Weiss, V.; Argyo, C.; von Schirnding, C.; Bein, T.; Bräuchle, C. Targeted drug delivery in cancer cells with red light photoactivated mesoporous silica nanoparticles. Nano Lett. 2013, 13, 2576-2583.
119. Lai, C.Y.; Trewyn, B.G.; Jeftinija, D.M.; Jeftinija, K.; Xu, S.; Jeftinija, S.; Lin, V.S. A mesoporous silica nanosphere-based carrier system with chemically removable CdS nanoparticle caps for stimuli-responsive controlled release of neurotransmitters and drug molecules. J. Am. Chem. Soc. 2003, 125, 4451-4459.
120. Liu, R.; Zhao, X.; Wu, T.; Feng, P. Tunable redox-responsive hybrid nanogated ensembles. J. Am. Chem. Soc. 2008, 130, 14418-14419.
121. Bernardos, A.; Aznar, E.; Marcos, M.D.; Martinez-Manez, R.; Sancenon, F.; Soto, J.; Barat, J.M.; Amoros, P. Enzyme-responsive controlled release using mesoporous silica supports capped with lactose. Angew. Chem. Int. Ed. 2009, 48, 5884-5887.
122. Coll, C.; Mondragon, L.; Martinez-Manez, R.; Sancenon, F.; Marcos, M.D.; Soto, J.; Amoros, P.; Perez-Paya, E. Enzyme-mediated controlled release systems by anchoring peptide sequences on mesoporous silica supports. Angew. Chem. Int. Ed. 2011, 50, 2138-2140.
123. Schlossbauer, A.; Kecht, J.; Bein, T. Biotin-Avidin as a protease-responsive cap system for controlled guest release from colloidal mesoporous silica. Angew. Chem. Int. Ed. 2009, 48, 3092-3095.
124. Chen, C.; Geng, J.; Pu, F.; Yang, X.; Ren, J.; Qu, X. Polyvalent nucleic acid/mesoporous silica nanoparticle conjugates: Dual stimuli-responsive vehicles for intracellular drug delivery. Angew. Chem. Int. Ed. 2011, 50, 882-886.
125. Angelos, S.; Choi, E.; Vogtle, F.; de Cola, L.; Zink, J.I. Photo-driven expulsion of molecules from mesostructured silica nanoparticles. J. Phys. Chem. C 2007, 111, 6589-6592.
126. Ferris, D.P.; Zhao, Y.L.; Khashab, N.M.; Khatib, H.A.; Stoddart, J.F.; Zink, J.I. Light-operated mechanized nanoparticles. J. Am. Chem. Soc. 2009, 131, 1686-1688.
127. Schlobauer, A.; Sauer, A.M.; Cauda, V.; Schmidt, A.; Engelke, H.; Rothbauer, U.; Zolghadr, K.; Leonhardt, H.; Bräuchle, C.; Bein, T. Cascaded photoinduced drug delivery to cells from multifunctional core-shell mesoporous silica. Adv. Healthc. Mater. 2012, 1, 316-320.
128. Climent, E.; Bernardos, A.; Martinez-Manez, R.; Maquieira, A.; Marcos, M.D.; Pastor-Navarro, N.; Puchades, R.; Sancenon, F.; Soto, J.; Amoros, P. Controlled delivery systems using antibody-capped mesoporous nanocontainers. J. Am. Chem. Soc. 2009, 131, 14075-14080.
129. Lee, C.H.; Cheng, S.H.; Huang, I.P.; Souris, J.S.; Yang, C.S.; Mou, C.Y.; Lo, L.W. Intracellular pH-responsive mesoporous silica nanoparticles for the controlled release of anticancer chemotherapeutics. Angew. Chem. Int. Ed. 2010, 49, 8214-8219.
130. Muhammad, F.; Guo, M.; Qi, W.; Sun, F.; Wang, A.; Guo, Y.; Zhu, G. pH-triggered controlled drug release from mesoporous silica nanoparticles via intracelluar dissolution of ZnO nanolids. J. Am. Chem. Soc. 2011, 133, 8778-8781.
131. Wei, Y.; Dong, H.; Xu, J.; Feng Q. Simultaneous immobilization of horseradish peroxidase and glucose oxidase in mesoporous sol-gel host materials. Chem. Phys. Chem. 2002, 3, 802-808.
132. Dai, Z.; Liu, S.; Ju, H.; Chen, H. Direct electron transfer and enzymatic activity of hemoglobin in a hexagonal mesoporous silica matrix. Biosens. Bioelectron. 2004, 19, 861-867.
133. Dai, Z.; Xu, X.; Ju, H. Direct electrochemistry and electrocatalysis of myoglobin immobilized on a hexagonal mesoporous silica matrix. Anal. Biochem. 2004, 332, 23-31.
134. Descalzo, A.B.; Marcos, M.D.; Martinez-Manez, R.; Soto, J.; Beltran, D.; Amoros, P. Anthrylmethylamine functionalised mesoporous silica-based materials as hybrid fluorescent chemosensors for ATP. J. Mater. Chem. 2005, 15, 2721-2731.
135. Radu, D.R.; Lai, C.Y.; Wiench, J.W.; Pruski, M.; Lin, V.S.Y. Gatekeeping layer effect: A poly(lactic acid)-coated mesoporous silica nanosphere-based fluorescence probe for detection of amino-containing neurotransmitters. J. Am. Chem. Soc. 2004, 126, 1640-1641.
136. Yang, M.; Li, H.; Javadi, A.; Gong, S. Multifunctional mesoporous silica nanoparticles as labels for the preparation of ultrasensitive electrochemical immunosensors. Biomaterials 2010, 31, 3281-3286.
137. Hurley, M.T.; Wang, Z.; Mahle, A.; Rabin, D.; Liu, Q.; English, D.S.; Zachariah, M.R.; Stein, D.; DeShong, P. Synthesis, characterization, and application of antibody functionalized fluorescent silica nanoparticles. Adv. Funct. Mater. 2013, 23, 3335-3343.
138. Calvert, R. Diatomaceous earth. J. Chem. Educ. 1930, 7. 2829.
139. Xiaohua, Q.; Mingzhu, L.; Zhenbin, C.; Rui, L. Preparation and properties of diatomite composite superabsorbent. Polym. Adv. Technol. 2007, 18, 184-193.
140. Korunic, Z. Diatomaceous Earths, a Group of Natural Insecticides. J. Stored Prod. Res. 1998, 34, 87-97.
141. Ivanov, S.E.; Belyakov, A.V. Diatomite and its applications. Glass Ceram. 2008, 65, 48-51.
142. Osmanlioglu, A.E. Natural diatomite process for removal of radioactivity from liquid waste. Appl. Radiat. Isot. 2007, 65, 17-20.
143. Al-Ghouti, M.A.; Khraisheh, M.A.M.; Allen, S.J.; Ahmad, M.N. The removal of dyes from textile wastewater: A study of the physical characteristics and adsorption mechanisms of diatomaceous earth. J. Environ. Manag. 2003, 69, 229-238.
144. Hsien, K.J.; Tsai, W.T.; Su, T.Y. Preparation of diatomite-TiO2 composite for photodegradation of bisphenol-A in water. J. Sol. Gel. Sci. Technol. 2009, 51, 63-69.
145. Zhu, Q.W.; Zhang, Y.H.; Zhou, F.S.; Lv, F.Z.; Ye, Z.F.; Fan, F.D.; Chu, P.K. Preparation and characterization of Cu2O-ZnO immobilized on diatomite for photocatalytic treatment of red water produced from manufacturing of TNT. Chem. Eng. J. 2011, 171, 61-68.
146. Hamm, C.E.; Merkel, R.; Springer, O.; Jurkojc, P.; Maier, C.; Prechtel, K.; Smetacek, V. Architecture and material properties of diatom shells provide effective mechanical protection. Nature 2003, 421, 841-843.
147. Butcher, K.S.A.; Ferris, J.M.; Philips, M.R.; Wintrebertt-Foquet, M.; Wah, J.W.J.; Jovanovic, N.; Vyverman, W.; Chepurnov, V. A luminescence study of porous diatoms. Mater. Sci. Eng. C 2005, 25, 658-663.
148. Fuhrmann, T.; Landwehr, S.; El Rharbi-Kucki, M.; Sumper, M. Diatoms as living photonic crystals. Appl. Phys. B 2004, 78, 257-260.
149. Payne, E.K.; Rosi, N.L.; Xue, C.; Mirkin, C.A. Sacrificial biological templates for the formation of nanostructured metallic microshells. Angew. Chem. 2005, 117, 5192-5195.
150. Sandhage, K.H. Materials "Alchemy": Shape-preserving chemical transformation of micro-to-macroscopic 3-D structures. JOM 2010, 62, 32-43.
151. Bao, Z.H.; Song, M.K.; Davis, S.C.; Cai, Y.; Liu, M.; Sandhage, K.H. High surface area, micro/mesoporous carbon particles with selecTable 3-D biogenic morphologies for tailored catalysis, filtration, or adsorption. Energy Environ. Sci. 2011, 4, 3980-3984.
152. Jeffryes, C.; Campbell, J.; Li, H.Y.; Jiao, J.; Rorrer, G. The potential of diatom nanobiotechnology for applications in solar cells, batteries, and electroluminescent devices. Energy Environ. Sci. 2011, 4, 3930-3941.
153. De Stefano, L.; Rendina, I.; De Stefano, M.; Bismuto, A.; Maddalena, P. Marine diatoms as optical chemical sensors. Appl. Phys. Lett. 2005, 87, 233902.
154. Lettieri, S.; Setaro, A.; De Stefano, L.; De Stefano, M.; Maddalena, P. The gas-detection properties of light-emitting diatoms. Adv. Funct. Mater. 2008, 8, 1257-1264.
155. Gale, D.K.; Gutu, T.; Jiao, J.; Chang, C.H.; Rorrer, G.L. Photoluminescence detection of biomolecules by antibody-functionalized diatom biosilica. Adv. Funct. Mater. 2009, 19, 926-933.
156. De Stefano, L.; Larnberti, A.; Rotiroti, L.; De Stefano, M. Interfacing the nanostructured biosilica microshells of the marine diatom Coscinodiscus wailesii with biological matter. Acta Biomater. 2008, 4, 126-130.
157. Townley, H.E.; Parker, A.R.; White-Cooper, H. Exploitation of diatom frustules for nanotechnology: Tethering active biomolecules. Adv. Funct. Mater. 2008, 18, 369-374.
158. Lin, K.C.; Kunduru, V.; Bothara, M.; Rege, K.; Prasad, S.; Ramakrishna, B.L. Biogenic nanoporous silica-based sensor for enhanced electrochemical detection of cardiovascular biomarkers proteins. Biosens. Bioelectron. 2010, 25, 2336-2342.
159. Aw, M.S.; Simovic, S.; Addai-Mensah, J.; Losic, D. Silica microcapsules from diatoms as new carrier for delivery of therapeutics. Nanomedicine 2011, 6, 1159-1173.
160. Aw, M.S.; Simovic, S.; Yu, Y.; Addai-Mensah, J.; Losic, D. Porous silica microshells from diatoms as biocarrier for drug delivery applications. Powder Technol. 2012, 223, 52-58.
161. Aw, M.S.; Bariana, M.; Yu, Y.; Addai-Mensah, J.; Losic, D. Surface functionalized diatom microcapsules for drug delivery of water-insoluble drugs. J. Biomater. Appl. 2013, 28, 163-174.
162. Bariana, M.; Aw, M.S.; Kurkuri, M.; Losic, D. Tuning drug loading and release properties of diatom silica microparticles by surface modifications. Int. J. Pharm. 2013, 443, 230-241.
163. Poulsen, N.; Berne, C.; Spain, J.; Kröger, N. Silica immobilization of an enzyme through genetic engineering of the diatom Thalassiosira pseudonana. Angew. Chem. Int. Ed. 2007, 46, 1843-1846.
164. Sheppard, V.C.; Scheffel, A.; Poulsen, N.; Kröger, N. Live diatom silica immobilization of multimeric and redox-Active enzymes. Appl. Environ. Microbiol. 2012, 78, 211-218.
165. Annenkov, V.V.; Patwardhan, S.V.; Belton, D.; Danilovtseva, E.N.; Perry, C.C. A new stepwise synthesis of a family of propylamines derived from diatom silaffins and their activity in silicification. Chem. Commun. 2006, 1521-1523.
166. Belton, D.J.; Patwardhan, S.V.; Annenkov, V.V.; Danilovtseva, E.N.; Perry, C.C. From biosilicification to tailored materials: Optimizing hydrophobic domains and resistance to protonation of polyamines. Proc. Natl. Acad. Sci. USA 2008, 105, 5963-5968.
167. Masse, S.; Laurent, G.; Chuburu, F.; Cadiou, C.; Dechamps, I.; Coradin, T. Modification of the Stöber process by a polyazamacrocycle leading to unusual core-shell silica nanoparticles Langmuir 2008, 24, 4026-4031.
168. Masse, S.; Laurent, G.; Coradin, T. Influence of cyclic polyamines on silica formation during the Stöber process. Phys. Chem. Chem. Phys. 2009, 11, 10204-10210.
169. Naik, R.R.; Whitlock, P.W.; Rodriguez, F.; Brott, L.L.; Glawe, D.D.; Clarson, S.J.; Stone, M.O. Controlled formation of biosilica structures in vitro. Chem. Commun. 2003, 238-239.
170. Rodríguez, F.; Glawe, D.D.; Naik, R.R.; Hallinan, K.P.; Stone, M.O. Study of the chemical and physical influences upon in vitro peptide-mediated silica formation. Biomacromolecules 2004, 5, 261-265.
171. Patwardhan, S.V.; Mukherjee, N.; Clarson, S.J. The use of poly-L-lysine to form novel silica morphologies and the role of polypeptides in biosilicification. J. Inorg. Organomet. Polym. 2001, 11, 193-198.
172. Patwardhan, S.V.; Mukherjee, N.; Steinitz-Kannan, M.; Clarson, S.J. Bioinspired synthesis of new silica structures. Chem. Commun. 2003, 1122-1123.
173. Tomczak, M.M.; Glawe, D.D.; Drummy, L.F.; Lawrence, C.G.; Stone, M.O.; Perry, C.C.; Pochan, D.J.; Deming, T.J.; Naik, R.R. Polypeptide-templated synthesis of hexagonal silica platelets. J. Am. Chem. Soc. 2005, 127, 12577-12582.
174. Patwardhan, S.V.; Maheshwari, R.; Mukherjee, N.; Kiick, K.L.; Clarson, S.J. Conformation and assembly of polypeptide scaffolds in templating the synthesis of silica: An example of a polylysine macromolecular "Switch". Biomacromolecules 2006, 7, 491-497.
175. McKenna, B.J.; Birkedal, H.; Bartl, M.H.; Deming, T.J.; Stucky, G.D. Micrometer-sized spherical assemblies of polypeptides and small molecules by acid-base chemistry. Angew. Chem. Int. Ed. 2004, 43, 5652-5655.
176. Pires, J.; Fernandes, A.C.; Avó, R. Bio-inspired synthesis of mesoporous silicas using large molecular weight poly-L-lysine at neutral pH. J. Mater. Sci. 2014, 49, 6087-6092.
177. Coradin, T.; Roux, C.; Livage, J. Biomimetic self-Activated formation of multi-scale porous silica in the presence of arginine-based surfactants. J. Mater. Chem. 2002, 12, 1242-1244.
178. Cha, J.N.; Stucky, G.D.; Morse, D.E.; Deming, T.J. Biomimetic synthesis of ordered silica structures mediated by block copolypeptides. Nature 2000, 403, 289-292.
179. Valéry, C.; Paternostre, M.; Robert, B.; Gulik-Krzywicki, T.; Narayanan, T.; Dedieu, J.C.; Keller, G.; Torres, M.L.; Cherif-Cheikh, R.; Calvo, P.; et al. Biomimetic organization: Octapeptide self-Assembly into nanotubes of viral capsid-like dimension. Proc. Natl. Acad. Sci. USA 2003, 100, 10258-10262.
180. Pouget, E.; Dujardin, E.; Cavalier, A.; Moreac, A.; Valéry, C.; Marchi-Artzner, V.; Weiss, T.; Renault, A.; Paternostre, M.; Artzner, F. Hierarchical architectures by synergy between dynamical template self-Assembly and biomineralization. Nat. Mater. 2007, 6, 434-439.
181. Wang, Q.; Zhang, J.Y.X.; Liu, D.; Zheng, J.; Pan, Y.; Lin, Y. Controlled biosilification using selfassembled short peptides A6K and V6K. RSC Adv. 2013, 3, 2784-2793.
182. Han, W.; MacEvan, S.R.; Chilkoti, A.; López, G.P. Bio-inspired synthesis of hybrid silica nanoparticles template from elastin-like polypeptide micelles. Nanoscale 2015, 7, 12038-12044.
183. Patwardhan, S.V.; Mukherjee, N.; Clarson, S.J. Effect of process parameters on the polymer mediated synthesis of silica at neutral pH. Silicon Chem. 2002, 1, 47-54.
184. Patwardhan, S.V.; Mukherjee, N.; Clarson, S.J. Formation of fiber-like amorphous silica structures by externally applied shear. J. Inorg. Organomet. Polym. 2001, 11, 117-121.
185. Patwardhan, S.V.; Clarson, S.J.; Silicification and biosilicification. Silicon Chem. 2002, 1, 207-214.
186. Jin, R.H.; Yuan, J.J. One-pot and rapid synthesis of uniformed silica spheres via mediation of linear poly(ethyleneimine)s and dyes. Polym. J. 2007, 39, 822-827.
187. Jin, R.H.; Yuan, J.J. Synthesis of poly(ethyleneimine)s-silica hybrid particles with complex shapes and hierarchical structures. Chem. Commun. 2005, 1399-1401.
188. Yuan, J.J.; Jin, R.H. Multiply shaped silica mediated by aggregates of linear poly(ethyleneimine). Adv. Mater. 2005, 17, 885-888.
189. Jin, R.H.; Yuan, J.J. Simple synthesis of hierarchically structured silicas by poly(ethyleneimine) aggregates preorganized by media modulation. Macromol. Chem. Phys. 2005, 206, 2160-2170.
190. Yuan, J.J.; Zhu, P.X.; Fukazawa, N.; Jin, R.H. Synthesis of nanofiber-based silica networks mediated by organized poly(ethylene imine): Structure, properties, and mechanism. Adv. Funct. Mater. 2006, 16, 2205-2212.
191. Knecht, M.R.; Wright, D.W. Amine-terminated dendrimers as biomimetic templates for silica nanosphere formation. Langmuir 2004, 20, 4728-4732.
192. Knecht, M.R.; Sewell, S.L.; Wright, D.W. Size control of dendrimer-templated silica. Langmuir 2005, 21, 2058-2061.
193. Neville, F.; Broderick, M.J.; Gibson, T.; Millner, P.A. Fabrication and activity of silicate nanoparticles and nanosilicate-entrapped enzymes using polyethyleneimine as a biomimetic polymer. Langmuir 2011, 27, 279-285.
194. Kristensen, J.B.; Meyer, R.L.; Poulsen, C.H.; Kragh, K.M.; Besenbacher, F.; Laursen, B.S. Biomimetic silica encapsulation of enzymes for replacement of biocides in antifouling coatings. Green Chem. 2010, 12, 387-394.
195. Berne, C.; Betancor, L.; Luckarift, H.R.; Spain, J.C. Application of a microfluidic reactor for screening cancer prodrug activation using silica-immobilized nitrobenzene nitroreductase. Biomacromolecules 2006, 7, 2631-2636.
196. Betancor, L.; Berne, C.; Luckarift, H.R.; Spain, J.C. Coimmobilization of a redox enzyme and a cofactor regeneration system. Chem. Commun. 2006, 3640-3642.
197. Cui, J.; Liang, L.; Han, C.; Liu. R. Stabilization of phenylalanine ammonia lyase from Rhodotorula glutinis by encapsulation in polyethyleneimine-mediated biomimetic silica. Appl. Biochem. Biotechnol. 2015, 176, 999-1011.
198. Miller, S.A.; Hong, E.D.; Wright, D. Rapid and efficient enzyme encapsulation in a dendrimer silica nanocomposite. Macromol. Biosci. 2006, 6, 839-845.
199. Forsyth, C.; Yip, T.W.S.; Patwardhan, S.V. CO2 sequestration by enzyme immobilized onto bioinspired silica. Chem. Commun. 2013, 49, 3191-3193.
200. Luckarift, H.R.; Dickerson, M.B.; Sandhage, K.H.; Spain, J.C. Rapid, room-temperature synthesis of antibacterial bionanocomposites of lysozyme with amorphous silica or titania. Small 2006, 2, 640-643.
201. Ramanathan, M.; Luckarift, H.R.; Sarsenova, A.; Wild, J.R.; Ramanculov, E.K.; Olsen, E.V.; Simonian, A.L. Lysozyme-mediated formation of protein-silica nano-composites for biosensing applications. Colloids Surf. 2009, 73, 58-64.
202. Luckarift, H.R.; Balasubramanian, S.; Paliwal, S.; Johnson, G.R.; Simonian, A.L. Enzyme-encapsulated silica monolayers for rapid functionalization of a gold surface. Colloids Surf. 2007, 58, 28-33.
203. Ivnitski, D.; Artyushkova, K.; Rincon, R.A.; Atanassov, P.; Luckarift, H.R.; Johnson, G.R. Entrapment of enzymes and carbon nanotubes in biologically synthesized silica: Glucose oxidase-catalyzed direct electron transfer. Small 2008, 4, 357-364.
204. Luan, P.P.; Jiang, Y.J.; Zhang, S.P.; Gao, J.; Su, Z.G.; Ma, G.H.; Zhang, Y.F. Chitosan-mediated formation of biomimetic silica nanoparticles: An effective method for manganese peroxidise immobilization and stabilization. J. Biosci. Bioeng. 2014, 118, 575-582.
205. Luckarift, H.R.; Spain, J.C.; Naik, R.R.; Stone, M.O. Enzyme immobilization in a biomimetic silica support. Nat. Biotechnol. 2004, 22, 211-213.
206. Naik, R.R.; Tomczak, M.M.; Luckarift, H.R.; Spain, J.C.; Stone, M.O. Entrapment of enzymes and nanoparticles using biomimetically synthesized silica. Chem. Commun. 2004, 1684-1685.
207. Fragai, M.; Luchinat, C.; Martelli, T.; Ravera, E.; Sagi, I.; Solomonov, I.; Udi, Y. SSNMR of biosilica-entrapped enzymes permits an easy assessment of preservation of native conformation in atomic detail. Chem. Comm. 2014, 50, 421-423.
208. Coradin, T.; Coupé, A.; Livage, J. Interactions of bovine serum albumin and lysozyme with sodium silicate solutions. Colloids Surf. B 2003, 29, 189-196.
209. Cardoso, M.B.; Luckarift, H.R.; Urban, V.S.; O'Neill, H.; Johnson, G.R. Protein localization in silica nanospheres derived via biomimetic mineralization. Adv. Funct. Mater. 2010, 20, 3031-3038.
210. Nam, D.H.; Won, K.; Kim, Y.H.; Sang, B.I. A novel route for immobilization of proteins to silica particles incorporating silaffin domains. Biotechnol. Progr. 2009, 25, 1643-1649.
211. Marner, W.D.; Shaikh, A.S.; Muller, S.J.; Keasling, J.D. Enzyme immobilization via silaffin-mediated autoencapsulation in a biosilica support. Biotechnol. Progr. 2009, 25, 417-423.
212. Jo, B.H.; Seo, J.H.; Yang, Y.J.; Baek, K.; Choi, Y.S.; Pack, S.P.; Oh, S.H.; Cha, H.J. Bioinspired silica nanocomposite with autoencapsulated carbonic anhydrase as a robust biocatalyst for CO2 sequestration. ACS Catal. 2014, 4, 4332-4340.
213. Choi, O.; Kim, B.C.; An, J.H.; Min, K.; Kim, Y.H.; Um, Y.; Oh, M.K.; Sang, B.I. A biosensor based on the self-entrapment of glucose oxidase within biomimetic silica nanoparticles induced by a fusion enzyme. Enzyme Microb. Technol. 2011, 49, 441-445.
214. Nam, D.H.; Lee, J.O.; Sang, B.I.; Won, K.; Kim, Y.H. Silaffin peptides as a novel signal enhancer for gravimetric biosensors. Appl. Biochem. Biotechnol. 2013, 170, 25-31.
215. Muir, T.W.; Sondhi, D.; Cole P.A. Expressed protein ligation: A general method for protein engineering. Proc. Natl. Acad. Sci. USA 1998, 95, 6705-6710.
216. Lechner, C.C.; Becker, C.F.W. Immobilising proteins on silica with site-specifically attached modified silaffin peptides. Biomater. Sci. 2015, 3, 288-297.
217. Lechner, C.C.; Becker, C.F.W. Modified silaffin R5 peptides enable encapsulation and release of cargo molecules from biomimetic silica particles. Bioorg. Med. Chem. 2013, 21, 3533-3541.
218. Luckarift, H.R.; Johnson, G.R.; Spain, J.C. Silica-immobilized enzyme reactors: Application to cholinesterase-inhibition studies. J. Chromatogr. B 2006, 843, 310-316.
219. Ding, L.H.; Zhang, Y.X.; Li, G.H. Recent Research Progress on Magnetic Nanocomposites with Silica Shell Structures Preparation and Nanotheranostic Applications. Recent Pat. Nanotechnol. 2014, 8, 117-128.
220. Brott, L.L.; Naik, R.R.; Pikas, D.J.; Kirkpatrick, S.M.; Tomlin, D.W.; Whitlock, P.W.; Clarson, S.J.; Stone, M.O. Ultrafast holographic nanopatterning of biocatalytically formed silica. Nature 2001, 413, 291-293.
221. Coffman, E.A.; Melechko, A.V.; Allison, D.P.; Simpson, M.L.; Doktycz, M.J. Surface patterning of silica nanostructures using bio-inspired templates and directed synthesis. Langmuir 2004, 20, 8431-8436.
222. Betancor, L.; Luckarift, H.R.; Seo, J.H.; Brand, O.; Spain, J.C. Three dimensional immobilization of -galactosidase on a silicon surface. Biotechnol. Bioeng. 2008, 99, 261-267.
223. Vamvakaki, V.; Hatzimarinaki, M.; Chaniotakis, N. Biomimetically synthesized silica-carbon nanofiber architectures for the development of highly stable electrochemical biosensor systems. Anal. Chem. 2008, 80, 5970-5975.
224. Hatzimarinaki, M.; Vamvakaki, V.; Chaniotakis, N. Spectro-electrochemical studies of acetylcholinesterase in carbon nanofiber-bioinspired silica nanocomposites for biosensor development. J. Mater. Chem. 2009, 19, 428-433.
225. Kim, I.Y.; Joachim, E.; Choi, H.; Kim, K. Toxicity of silica nanoparticles depends on size, dose, and cell type. Nanomed. Nanotechnol. Biol. Med.2015, 11, 1407-1416.
226. Gehrke, H.; Frühmesser, A.; Pelka, J.; Esselen, M.; Hecht, L.L.; Blank, H.; Schuchmann, H.P.; Gerthsen, D.; Marquardt, C.; Diabaté, S.; et al. In vitro toxicity of amorphous silica nanoparticles in human colon carcinoma cells. Nanotoxicology 2013, 7, 274-293.
227. Tenzer, S.; Docter, D.; Kuharev, J.; Musyanovych, A.; Fetz, V.; Hecht, R.; Schlenk, F.; Fischer, D.; Kiouptsi, K.; Reinhardt, C.; et al. Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology. Nat. Nanotechnol. 2013, 8, 772-781.
228. Shemetov, A.A.; Nabiev, I.; Sukhanova, A. Molecular interaction of proteins and peptides with nanoparticles. ACS Nano 2012, 6, 4585-4602.
229. Cedervall, T.; Lynch, I.; Lindman, S.; Berggard, T.; Thulin, E.; Nilsson, H.; Dawson, K.A.; Linse, S. Probing the interactions of proteins and nanoparticles. Proc. Natl. Acad. Sci. USA 2007, 104, 2050-2055.