RDW to Platelet Ratio: A Novel Noninvasive Index for Predicting Hepatic Fibrosis and Cirrhosis in Chronic Hepatitis B

PLoS ONE

Volumn 8, Issue 7, 2013, Pages

  Chen, Baode ^a   Ye, Bo ^a   Zhang, Jian ^a   Ying, Lixiong ^a   Chen, Yu ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; HEMOGLOBIN; HEPATITIS B(E) ANTIGEN; VIRUS DNA;

ACCURACY; ADULT; AGE; AREA UNDER THE CURVE; ARTICLE; BIOCHEMISTRY; BLOOD CELL COUNT; COHORT ANALYSIS; CONTROLLED STUDY; DEMOGRAPHY; DIAGNOSTIC TEST ACCURACY STUDY; ERYTHROCYTE DISTRIBUTION WIDTH; ERYTHROCYTE PARAMETERS; FEMALE; HEMATOLOGICAL PARAMETERS; HEPATITIS B; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LIVER BIOPSY; LIVER CIRRHOSIS; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; NON INVASIVE MEASUREMENT; PREDICTION; PREDICTIVE VALUE; PROGNOSIS; RECEIVER OPERATING CHARACTERISTIC; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SEX RATIO; THROMBOCYTE COUNT;

ADULT; AREA UNDER CURVE; COHORT STUDIES; ERYTHROCYTES; FEMALE; HEPATITIS B, CHRONIC; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PLATELET COUNT;

EID: 84880736312     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0068780     Document Type: Article

References (43)

1. EASL Clinical Practice Guidelines: management of chronic hepatitis B. Journal of hepatology. 50: 227-242.
2. EASL clinical practice guidelines: Management of chronic hepatitis B virus infection. Journal of hepatology 57: 167-185.
3. Liaw YF, Leung N, Kao JH, Piratvisuth T, Gane E, et al. (2008) Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2008 update. Hepatology international 2: 263-283.
4. Regev A, Berho M, Jeffers LJ, Milikowski C, Molina EG, et al. (2002) Sampling error and intraobserver variation in liver biopsy in patients with chronic HCV infection. The American journal of gastroenterology 97: 2614-2618.
5. Imbert-Bismut F, Ratziu V, Pieroni L, Charlotte F, Benhamou Y, et al. (2001) Biochemical markers of liver fibrosis in patients with hepatitis C virus infection: a prospective study. Lancet 357: 1069-1075.
6. Koda M, Matunaga Y, Kawakami M, Kishimoto Y, Suou T, et al. (2007) FibroIndex, a practical index for predicting significant fibrosis in patients with chronic hepatitis C. Hepatology. 45: 297-306.
7. Wai CT, Greenson JK, Fontana RJ, Kalbfleisch JD, Marrero JA, et al. (2003) A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology. 38: 518-526.
8. Vallet-Pichard A, Mallet V, Pol S (2006) FIB-4: a simple, inexpensive and accurate marker of fibrosis in HCV-infected patients. Hepatology 44: 769; author reply 769-770.
9. Castera L (2012) Noninvasive methods to assess liver disease in patients with hepatitis B or C. Gastroenterology 142: 1293-1302 e1294.
10. Hui AY, Chan HL, Wong VW, Liew CT, Chim AM, et al. (2005) Identification of chronic hepatitis B patients without significant liver fibrosis by a simple noninvasive predictive model. The American journal of gastroenterology 100: 616-623.
11. Zeng MD, Lu LG, Mao YM, Qiu DK, Li JQ, et al. (2005) Prediction of significant fibrosis in HBeAg-positive patients with chronic hepatitis B by a noninvasive model. Hepatology 42: 1437-1445.
12. Pradella P, Bonetto S, Turchetto S, Uxa L, Comar C, et al. (2011) Platelet production and destruction in liver cirrhosis. Journal of hepatology 54: 894-900.
13. Chen PC, Sung FC, Chien KL, Hsu HC, Su TC, et al. (2010) Red blood cell distribution width and risk of cardiovascular events and mortality in a community cohort in Taiwan. American journal of epidemiology 171: 214-220.
14. Patel KV, Ferrucci L, Ershler WB, Longo DL, Guralnik JM, (2009) Red blood cell distribution width and the risk of death in middle-aged and older adults. Archives of internal medicine 169: 515-523.
15. Horne BD, (2012) A changing focus on the red cell distribution width: why does it predict mortality and other adverse medical outcomes? Cardiology 122: 213-215.
16. Bojakowski K, Dzabic M, Kurzejamska E, Styczynski G, Andziak P, et al. (2012) A high red blood cell distribution width predicts failure of arteriovenous fistula. PloS one 7: e36482.
17. Anand I, McMurray JJ, Whitmore J, Warren M, Pham A, et al. (2004) Anemia and its relationship to clinical outcome in heart failure. Circulation 110: 149-154.
18. Anonymous (2000) Management scheme of diagnostic and therapy criteria of viral hepatitis Zhonghua Gan Zang Bing Za Zhi (Chinese J Hepatol). 6: 324-329.
19. Bedossa P, Poynard T, (1996) An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. Hepatology 24: 289-293.
20. Giannini E, Risso D, Botta F, Chiarbonello B, Fasoli A, et al. (2003) Validity and clinical utility of the aspartate aminotransferase-alanine aminotransferase ratio in assessing disease severity and prognosis in patients with hepatitis C virus-related chronic liver disease. Archives of internal medicine 163: 218-224.
21. Sterling RK, Lissen E, Clumeck N, Sola R, Correa MC, et al. (2006) Development of a simple noninvasive index to predict significant fibrosis in patients with HIV/HCV coinfection. Hepatology 43: 1317-1325.
22. Duclos B, Bories P, Mirouze D, Navarro M, Michel H, (1983) [Anemia caused by acanthocytosis in the cirrhotic patient: diagnosis and prognostic significance. 3 cases]. Annales de medecine interne 134: 643-646.
23. McHutchison JG, Manns MP, Longo DL, (2006) Definition and management of anemia in patients infected with hepatitis C virus. Liver international: official journal of the International Association for the Study of the Liver 26: 389-398.
24. Lou Y, Wang M, Mao W, (2012) Clinical usefulness of measuring red blood cell distribution width in patients with hepatitis B. PloS one. 7: e37644.
25. Alkhouri N, Morris-Stiff G, Campbell C, Lopez R, Tamimi TA, et al. (2012) Neutrophil to lymphocyte ratio: a new marker for predicting steatohepatitis and fibrosis in patients with nonalcoholic fatty liver disease. Liver international: official journal of the International Association for the Study of the Liver 32: 297-302.
26. Purnak T, Olmez S, Torun S, Efe C, Sayilir A, et al. (2012) Mean platelet volume is increased in chronic hepatitis C patients with advanced fibrosis. Clinics and research in hepatology and gastroenterology.
27. Ekiz F, Yuksel O, Kocak E, Yilmaz B, Altinbas A, et al. (2011) Mean platelet volume as a fibrosis marker in patients with chronic hepatitis B. Journal of clinical laboratory analysis. 25: 162-165.
28. Uyarel H, Ergelen M, Cicek G, Kaya MG, Ayhan E, et al. (2011) Red cell distribution width as a novel prognostic marker in patients undergoing primary angioplasty for acute myocardial infarction. Coronary artery disease 22: 138-144.
29. Dabbah S, Hammerman H, Markiewicz W, Aronson D, (2010) Relation between red cell distribution width and clinical outcomes after acute myocardial infarction. The American journal of cardiology 105: 312-317.
30. Jin W, Lin Z, Xin Y, Jiang X, Dong Q, et al. (2012) Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis B-related fibrosis: a leading meta-analysis. BMC gastroenterology 12: 14.
31. Wong GL, Wong VW, Choi PC, Chan AW, Chum RH, et al. (2008) Assessment of fibrosis by transient elastography compared with liver biopsy and morphometry in chronic liver diseases. Clinical gastroenterology and hepatology: the official clinical practice journal of the American Gastroenterological Association 6: 1027-1035.
32. Poynard T, Zoulim F, Ratziu V, Degos F, Imbert-Bismut F, et al. (2005) Longitudinal assessment of histology surrogate markers (FibroTest-ActiTest) during lamivudine therapy in patients with chronic hepatitis B infection. The American journal of gastroenterology 100: 1970-1980.
33. Mallet V, Dhalluin-Venier V, Roussin C, Bourliere M, Pettinelli ME, et al. (2009) The accuracy of the FIB-4 index for the diagnosis of mild fibrosis in chronic hepatitis B. Alimentary pharmacology & therapeutics. 29: 409-415.
34. Kim BK, Kim SU, Kim HS, Park JY, Ahn SH, et al. (2012) Prospective validation of FibroTest in comparison with liver stiffness for predicting liver fibrosis in Asian subjects with chronic hepatitis B. PloS one. 7: e35825.
35. Seto WK, Lee CF, Lai CL, Ip PP, Fong DY, et al. (2011) A new model using routinely available clinical parameters to predict significant liver fibrosis in chronic hepatitis B. PloS one. 6: e23077.
36. Knight V, Tchongue J, Lourensz D, Tipping P, Sievert W, (2012) Protease-activated receptor 2 promotes experimental liver fibrosis in mice and activates human hepatic stellate cells. Hepatology 55: 879-887.
37. Sitia G, Aiolfi R, Di Lucia P, Mainetti M, Fiocchi A, et al. (2012) Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B. Proceedings of the National Academy of Sciences of the United States of America. 109: E2165-2172.
38. Ripoche J, (2011) Blood platelets and inflammation: their relationship with liver and digestive diseases. Clinics and research in hepatology and gastroenterology 35: 353-357.
39. Watanabe M, Murata S, Hashimoto I, Nakano Y, Ikeda O, et al. (2009) Platelets contribute to the reduction of liver fibrosis in mice. Journal of gastroenterology and hepatology 24: 78-89.
40. Allen LA, Felker GM, Mehra MR, Chiong JR, Dunlap SH, et al. (2010) Validation and potential mechanisms of red cell distribution width as a prognostic marker in heart failure. Journal of cardiac failure 16: 230-238.
41. Ramm GA, Ruddell RG, (2010) Iron homeostasis, hepatocellular injury, and fibrogenesis in hemochromatosis: the role of inflammation in a noninflammatory liver disease. Seminars in liver disease 30: 271-287.
42. Ruddell RG, Hoang-Le D, Barwood JM, Rutherford PS, Piva TJ, et al. (2009) Ferritin functions as a proinflammatory cytokine via iron-independent protein kinase C zeta/nuclear factor kappaB-regulated signaling in rat hepatic stellate cells. Hepatology 49: 887-900.
43. Chan HL, Wong ML, Hui AY, Hung LC, Chan FK, et al. (2003) Hepatitis B virus genotype C takes a more aggressive disease course than hepatitis B virus genotype B in hepatitis B e antigen-positive patients. Journal of clinical microbiology 41: 1277-1279.