Loss of cyclin-dependent kinase 2 (CDK2) inhibitory phosphorylation in a CDK2AF knock-in mouse causes misregulation of DNA replication and centrosome duplication

Molecular and Cellular Biology

Volumn 32, Issue 8, 2012, Pages 1421-1432

  Zhao, Hui ^a   Chen, Xueyan ^a,b   Mark, Gurian West ^a,c   Roberts, James M ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c PORTLAND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYCLIN A; CYCLIN DEPENDENT KINASE 2; CYCLIN E; PHENYLALANINE; RETINOBLASTOMA PROTEIN; THREONINE; TYROSINE;

ARTICLE; BIOACCUMULATION; CELL CYCLE CHECKPOINT; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CENTROSOME; CHROMOSOME DUPLICATION; DNA DAMAGE; DNA REPLICATION; DOWN REGULATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; FEMALE; GENOTYPE; HOMOLOGOUS RECOMBINATION; IMMUNOFLUORESCENCE; INHIBITION KINETICS; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOUTHERN BLOTTING;

AMINO ACID SUBSTITUTION; ANIMALS; CELL CYCLE; CENTROSOME; CYCLIN A; CYCLIN E; CYCLIN-DEPENDENT KINASE 2; DNA DAMAGE; DNA REPLICATION; MICE; PHOSPHORYLATION; S PHASE CELL CYCLE CHECKPOINTS;

EID: 84861309646     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.06721-11     Document Type: Article

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