Enhanced antitumour drug delivery to cholangiocarcinoma through the apical sodium-dependent bile acid transporter (ASBT)

Journal of Controlled Release

Volumn 216, Issue , 2015, Pages 93-102

  Lozano, Elisa ^a   Monte, Maria J ^a,c   Briz, Oscar ^a,c   Hernández Hernández, Angel ^a   Banales, Jesus M ^b,c   Marin, Jose J G ^a,c   Macias, Rocio I R ^a,c  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Biliary tumour; Cancer; Chemoresistance; Chemotherapy; Cisplatin; Drug targeting; Ursodeoxycholic acid

Indexed keywords

AMINO ACIDS; BODY FLUIDS; CELL CULTURE; CHEMOTHERAPY; DISEASES; PLATINUM COMPOUNDS; RATS; TISSUE;

CANCER; CHEMORESISTANCE; CIS-PLATIN; DRUG-TARGETING; URSODEOXYCHOLIC ACID;

TUMORS;

BILE ACID CONJUGATE; CISPLATIN; CYTOSTATIC AGENT; GLYCOCHOLIC ACID; SODIUM BILE ACID COTRANSPORTER; URSODEOXYCHOLIC ACID; ANTINEOPLASTIC AGENT; BAMET-UD2; COTRANSPORTER; ORGANIC ANION TRANSPORTER; PLATINUM COMPLEX; SODIUM-BILE ACID COTRANSPORTER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BILE DUCT CARCINOMA; CANCER CHEMOTHERAPY; DRUG CONJUGATION; DRUG PROTEIN BINDING; DRUG TARGETING; DRUG TUMOR LEVEL; FROZEN SECTION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STABLE EXPRESSION; AGED; ANIMAL; BILE DUCT NEOPLASMS; CELL PROLIFERATION; CHEMISTRY; CHOLANGIOCARCINOMA; DRUG DELIVERY SYSTEM; DRUG EFFECTS; FEMALE; METABOLISM; MIDDLE AGED; MOUSE; NUDE MOUSE; TUMOR CELL LINE; VERY ELDERLY; WISTAR RAT;

AGED; AGED, 80 AND OVER; ANIMALS; ANTINEOPLASTIC AGENTS; BILE DUCT NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CHOLANGIOCARCINOMA; CISPLATIN; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; MALE; MICE; MICE, NUDE; MIDDLE AGED; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; ORGANOPLATINUM COMPOUNDS; RATS; RATS, WISTAR; SYMPORTERS; URSODEOXYCHOLIC ACID;

EID: 84940186205     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.08.022     Document Type: Article

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