Notching up on the cellular origins of intrahepatic cholangiocarcinoma

Hepatology

Volumn 57, Issue 4, 2013, Pages 1668-1671

  Sirica, Alphonse E ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE CELL ADHESION MOLECULE;

BILE DUCT CARCINOMA; CELL DIFFERENTIATION; CELL TYPE; CLINICAL FEATURE; HUMAN; HUMAN CELL; LIVER CELL; NOTE; PHENOTYPE; PRIORITY JOURNAL; STEM CELL;

EID: 84876113208     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26313     Document Type: Note

References (19)

1. Hammill CW, Wong LL. Intrahepatic cholangiocarcinoma: a malignancy of increasing importance. J Am Coll Surg 2008; 207: 594-603.
2. Bartlett DL. Intrahepatic cholangiocarcinoma: a worthy challenge. Cancer J 2009; 15: 255-256.
3. Yamamoto M, Ariizumi S. Surgical outcomes of intrahepatic cholangiocarcinoma. Surg Today 2011; 41: 896-902.
4. Razumilava N, Gores GJ. Classification, diagnosis, and management of cholangiocarcinoma. Clin Gastroenterol Hepatol 2013; 11: 13-21.e1; quiz, e3-4.
5. Nakanuma Y, Sato Y, Harada K, Sasaki M, Xu J, Ikeda H. Pathological classification of intrahepatic cholangiocarcinoma based on a new concept. World J Hepatol 2010; 2: 419-427.
6. Sempoux C, Jibara G, Ward SC, Fan C, Qin L, Roayaie S, et al. Intrahepatic cholangiocarcinoma: new insights in pathology. Semin Liver Dis 2011; 31: 49-60.
7. Cardinale V, Carpino G, Reid L, Gaudio E, Alvaro D. Multiple cells of origin in cholangiocarcinoma underlie biological, epidemiological and clinical heterogeneity. World J Gastrointest Oncol 2012; 4: 94-102.
8. Carpino G, Carcinale V, Reid L, Alvaro D, Gaudio E. Cells of origin and cancer stem cells in cholangiocarcinoma. Transl Gastrointest Cancer 2012; 1: 33-43.
9. Tsuchiya A, Kamimura H, Tamura Y, Takamura M, Yamagiwa S, Suda T, et al. Hepatocellular carcinoma with progenitor cell features distinguishable by the hepatic stem/progenitor cell marker NCAM. Cancer Lett 2011; 309: 95-103.
10. Komuta M, Spee B, Vander Borght S, De Vos R, Verslype C, Aerts R, et al. Clinicopathological study on cholangiolocellular carcinoma suggesting hepatic progenitor cell origin. HEPATOLOGY 2008; 47: 1544-1556.
11. Maeno S, Kondo F, Sano K, Takada T, Asano T. Morphometric and immunohistochemical study of cholangiolocellular carcinoma: comparison with non-neoplastic cholangiole, interlobular duct, and septal duct. J Hepatobiliary Pancreat Sci 2012; 19: 289-296.
12. Torbenson M, Yeh MM, Abraham SC. Bile duct dysplasia in the setting of chronic hepatitis C and alcohol cirrhosis. Am J Surg Pathol 2007; 31: 1410-1413.
13. Rougemont A-L, Genevay M, McKee TA, Gremaud M, Mentha G, Rubbia-Brandt L. Extensive biliary intraepithelial neoplasia (BilIN) and multifocal early intrahepatic cholangiocarcinoma in non-biliary cirrhosis. Virchows Arch 2010; 456: 711-717.
14. Zen Y, Quaglia A, Heaton N, Rela M, Portmann B. Two distinct pathways of carcinogenesis in primary sclerosing cholangitis. Histopathology 2011; 59: 1100-1110.
15. Sirica AE. Ductular hepatocytes. Histol Histopathol 1995; 10: 433-456.
16. Fan B, Malato Y, Calvisi DF, Naqvi S, Razumilava N, Ribback S, et al. Cholangiocarcinomas can originate from hepatocytes in mice. J Clin Invest 2012; 122: 2911-2915.
17. Sekiya S, Suzuki A. Intrahepatic cholangiocarcinoma can arise from Notch-mediated conversion of hepatocytes. J Clin Invest 2012; 122: 3914-3918.
18. Sapisochin G, Fidelman N, Roberts JP, Yao FY. Mixed hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma in patients undergoing transplantation for hepatocellular carcinoma. Liver Transpl 2011; 17: 934-942.
19. Villanueva A, Alsinet C, Yanger K, Hoshida Y, Zong Y, Toffanin S, et al. Notch signaling is activated in human hepatocellular carcinoma and induces tumor formation in mice. Gastroenterology 2012; 143: 1660-1669.