Pregabalin role in inhibition of morphine analgesic tolerance and physical dependency in rats

European Journal of Pharmacology

Volumn 742, Issue , 2014, Pages 113-117

  Hasanein, Parisa ^a   Shakeri, Saeed ^a  

^a BU ALI SINA UNIVERSITY   (Iran)

Author keywords

Dependency; Morphine; Pregabalin; Rats; Tolerance

Indexed keywords

4 AMINOBUTYRIC ACID; MORPHINE; NALOXONE; PREGABALIN; NARCOTIC ANALGESIC AGENT;

ANALGESIA; ANTINOCICEPTION; ARTICLE; CHRONIC PAIN; CONDITIONED PLACE PREFERENCE TEST; CONTROLLED STUDY; DOPAMINE RELEASE; DOPAMINERGIC NERVE CELL; DRUG TOLERANCE; DRUG WITHDRAWAL; GABAERGIC SYSTEM; GROOMING; HYPERALGESIA; JUMPING; LICKING; LOW BACK PAIN; MALE; MORPHINE ADDICTION; NEUROTRANSMISSION; NONHUMAN; OPIATE ADDICTION; PAW; PENIS; PRIORITY JOURNAL; RAT; REACTION TIME; REARING; SNIFFING; STANDING; TAIL FLICK TEST; TREMOR; WEIGHT REDUCTION; WET DOG SHAKES; WITHDRAWAL SYNDROME; ANALOGS AND DERIVATIVES; ANIMAL; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; MORPHINE DEPENDENCE; PAIN MEASUREMENT; PATHOPHYSIOLOGY; PHYSIOLOGY; SUBSTANCE WITHDRAWAL SYNDROME; WISTAR RAT;

ANALGESICS, OPIOID; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; GAMMA-AMINOBUTYRIC ACID; MALE; MORPHINE; MORPHINE DEPENDENCE; PAIN MEASUREMENT; RATS; RATS, WISTAR; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 84940041344     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.08.030     Document Type: Article

References (47)

1. Aracil-Fernández, A., Almela, P., Manzanares, J., Pregabalin and topiramate regulate behavioural and brain gene transcription changes induced by spontaneous cannabinoid withdrawal in mice. Addict. Biol. 18 (2013), 252–562.
2. Andrews, N., Loomis, S., Blake, R., Ferrigan, L., Singh, L., McKnight, A.T., Effect of gabapentin-like compounds on development and maintenance of morphineinduced conditioned place preference. Psychopharmacol 157 (2001), 381–387.
3. Asl, B.H., Hassanzadeh, K., Khezri, E., Mohammadi, S., Evaluation the effects of dextromethorphan and midazolam on morphine induced tolerance and dependence in mice. Pak. J. Biol. Sci. 11 (2008), 1690–1695.
4. Bauer, C.S., Nieto-Rostro, M., Rahman, W., Tran-Van-Minh, A., Ferron, L., Douglas, L., Kadurin, I., Ranjan, Y Sri, Fernandez-Alacid, L., Millar, N.S., Dickenson, A.H., Lujan, R., Dolphin, A.C., The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals inneuropathic pain is inhibited by the alpha2delta ligand pregabalin. J. Neurosci. 29 (2009), 4076–4088.
5. Dauri, M., Faria, S., Gatti, A., Celidonio, L., Carpenedo, R., Sabato, A.F., Gabapentin and pregabalin for the acute post-operative pain management. A systematic-narrative review of the recent clinical evidences. Curr. Drug Targets 10 (2009), 716–733.
6. D'Amour, F.E., Smith, D.L., A method of determining loss of pain sensation. J. Pharmacol. Exp. Ther. 27 (1941), 74–79.
7. DeFeudis, F.V., Gamma-aminobutyric acid-ergic analgesia: implications for gamma-aminobutyric acid-ergic therapy for drug addictions. Drug Alcohol Depend. 14 (1984), 101–111.
8. Dobashi, T., Tanabe, S., Jin, H., Nishino, T., Aoe, T., Valproate attenuates the development of morphine antinociceptive tolerance. Neurosci. Lett. 485 (2010), 125–128.
9. Eckhardt, K., Ammon, S., Hofmann, U., Riebe, A., Gugeler, N., Mikus, G., Gabapentin enhances the analgesic effect of morphine in healthy volunteers. Anesth. Analg. 91 (2000), 185–191.
10. Errante, L.D., Petroff, O.A.C., Acute effects of gabapentin and pregabalin on rat forebrain cellular GABA, glutamate, andglutamine concentrations. Seizure 12 (2003), 300–306.
11. Field, M.J., Cox, P.J., Stott, E., Melrose, H., Offord, J., Su, T.Z., Bramwell, S., Corradini, L., England, S., Winks, J., Kinloch, R.A., Hendrich, J., Dolphin, A.C., Webb, T., Williams, D., Identification of the alpha2- delta-1 subunit of voltage-dependent calcium channels as a molecular target for pain mediating the analgesic actions of pregabalin. Proc. Natl. Acad. Sci. USA 103 (2006), 17537–17542.
12. Freedman, B.M., O'Hara, E., Pregabalin has opioid-sparing effects following augmentation mammaplasty. Aesthet. Surg. J. 28 (2008), 421–424.
13. Gajraj, N.M., Pregabalin: its pharmacology and use in pain management. Anesth. Analg. 105 (2007), 1805–1815.
14. Gilron, I., Biederman, J., Jhamandas, K., Hong, M., Gabapentin blocks and reverses antinociceptive morphine tolerance in the rat paw-pressure and tail-flick tests. Anesthesiology 98 (2003), 1288–1292.
15. Hara, K., Saito, Y., Kirihara, Y., Yamada, Y., Sakura, S., Kosaka, Y., The interaction of antinociceptive effects of morphine and GABA receptor agonists within the rat spinal cord. Anesth. Analg. 89 (1999), 422–427.
16. Heinricher, M.M., Tortorici, V., Interference with GABA transmission in the rostral ventromedial medulla: disinhibition of off-cells as a central mechanism in nociceptive modulation. Neuroscience 63 (1994), 533–546.
17. Hull, L.C., Gabra, B.H., Bailey, C.P., Henderson, G., Dewey, W.L., Reversal of morphine analgesic tolerance by ethanol in the mouse. J. Pharmacol. Exp. Ther. 345 (2013), 512–519.
18. Hurley, R.W., Chatterjea, D., Rose Feng, M., Taylor, C.P., Hammond, D.L., Gabapentin and pregabalin can interact synergistically with naproxen to produce antihyperalgesia. Anesthesiology 97 (2002), 1263–1273.
19. Hynes, M.D., McCarten, M.D., Shearman, G., Lal, H., Differential reduction of morphine-withdrawal body shakes by butaclamol enantiomers. Life Sci. 22 (1978), 133–136.
20. Kämmerer, N., Lemenager, T., Grosshans, M., Kiefer, F., Hermann, D., Pregabalin for the reduction of opiate withdrawal symptoms. Psychiatr. Prax 39 (2012), 351–352.
21. Kavoussi, R., Pregabalin: from molecule to medicine. Eur. Neuropsychopharmacol. 16:Suppl 2 (2006), S128–S133.
22. Keyhanfar, F., ShamsiMeymandi, M., Sepehri, G., Rastegaryanzadeh, R., Heravi, G., Evaluation of antinociceptive effect of pregabalin in mice and its combination with tramadol using tail flick Test. Iran J. Pharm. Res. 12 (2013), 483–493.
23. Knotkova, H., Pappagallo, M., Adjuvant analgesics. Med. Clin. N. Am. 91 (2007), 113–124.
24. Luo, Z.D., Chaplan, S.R., Higuera, E.S., Sorkin, L.S., Stauderman, K.A., Williams, M.E., Yaksh, T.L., Upregulation of dorsal root ganglion (alpha)2(delta) calcium channelsubunit and its correlation with allodynia in spinal nerve-injured rats. J. Neurosci. 21 (2001), 1868–1875.
25. Ma, J., Pan, Z.Z., Contribution of brainstem GABA(A) synaptic transmission to morphine analgesic tolerance. Pain 122 (2006), 163–173.
26. Matthews, E.A., Dickenson, A.H., A combination of gabapentin and morphine mediates enhanced inhibitory effects on dorsal horn neuronal responses in a rat model of neuropathy. Anesthesiology 96 (2002), 633–640.
27. Meymandi, M.S., Sepehri, G., Gabapentin action and interaction on the antinociceptive effect of morphine on visceral pain in mice. Eur. J. Anaesthesiol. 25 (2008), 129–134.
28. Meymandi, M.S., Sepehri, G., Mobasher, M., Gabapentin enhances the analgesic response to morphine in acute model of pain in male rats. Pharmacol. Biochem. Behav. 85 (2006), 185–189.
29. Micheva, K.D., Taylor, C.P., Smith, S.J., Pregabalin reduces the release of synaptic vesicles from cultured hippocampal neurons. Mol. Pharmacol. 70 (2006), 467–476.
30. Millan, M.J., Descending control of pain. Prog. Neurobiol. 66 (2002), 355–474.
31. Moore, R.A., Straube, S., Wiffen, P.J., Derry, S., Mc Quay, H.J., Pregabalin for acute and chronic pain in adults. Cochrane Database Syst. Rev., 3, 2009 (CD007076).
32. Oulis, P., Konstantakopoulos, G., Kouzoupis, A.V., Masdrakis, V.G., Karakatsanis, N.A., Karapoulios, E., Kontoangelos, K.A., Papadimitriou, G.N., Pregabalin in the discontinuation of long-term benzodiazepines׳ use. Hum. Psychopharmacology 23 (2008), 337–340.
33. Oulis, P., Konstantakopoulos, G., Efficacy and safety of pregabalin in the treatment of alcohol and benzodiazepine dependence. Expert Opin. Investig. Drugs. 21 (2012), 1019–1029.
34. Papazisis, G., Tzachanis, D., Pregabalin׳s abuse potential: a mini review focusing on the pharmacological profile. Int. J. Clin. Pharmacol. Ther. 52 (2014), 709–716.
35. Rahman, A.F., Takahashi, M., Kaneto, H., Role of GABAergic systems in the development of morphine tolerance in formalin-treated mice. Jpn. J. Pharmacol. 68 (1995), 207–211.
36. Rashvand, M., Khajavi, A., Parviz, M., Hasanein, P., Keshavarz, M., GABAA receptors are involved in the analgesic effects of morphine microinjected into the central nucleus of the amygdala. Clin. Exp. Pharmacol. Physiol. 41 (2014), 338–344.
37. Roberts, L.A., Beyer, C., Komisaruk, B.R., Nociceptive responses to altered GABAergic activity at the spinal cord. Life Sci. 39 (1986), 1667–1674.
38. Romano, C.L., Romano, D., Bonora, C., Mineo, G., Pregabalin, celecoxib, and their combination for treatment of chronic low-back pain. J. Orthop. Traumatol. 10 (2009), 185–191.
39. Shimoyama, M., Shimoyama, N., Inturrisi, C.E., Elliott, K.J., Gabapentin enhances the antinociceptive effects of spinal morphine in the rat tail-flick test. Pain 72 (1997), 375–382.
40. Sivam, S.P., Ho, I.K., GABA in morphine analgesia and tolerance. Life Sci. 37 (1985), 199–208.
41. Somogyi, A.A., Barratt, D.T., Coller, J.K., Pharmacogenetics of opioids. Clin. Pharmacol. Ther. 81 (2007), 429–444.
42. Suh, H.W., Song, D.K., Huh, S.O., Lee, K.C., Kim, Y.H., Differential potentiative effects of GABA receptor agonists in the production of antinociception induced by morphine and beta-endorphin administered intrathecally in the mouse. Life Sci. 66 (2000), PL61–PL69.
43. Sun, L., Hu, L., Li, Y., Cui, C., Mesoaccumbens dopamine signaling alteration underlies behavioral transition from tolerance to sensitization to morphine rewarding properties during morphine withdrawal. Brain Struct. Funct. 219 (2013), 1755–1771.
44. Ueda, H., Ueda, M., Mechanisms underlying morphine analgesic tolerance and dependence. Front. Biosci. 14 (2009), 5260–5272.
45. Wedekind, D., Bandelow, B., The alpha2delta subunit of the voltage-dependent calcium channel. A new pharmaceutical target for psychiatry and neurology. Nervenarzt 76 (2005), 888–891.
46. Yoon, I.S., Kim, H.S., Hong, J.T., Lee, M.K., Oh, K.W., Inhibition of muscimol on morphine-induced hyperactivity, reverse tolerance and postsynaptic dopamine receptor supersensitivity. Pharmacology 65 (2002), 204–209.
47. Zarrindast, M.R., Dinkoub, Z., Homayoun, H., Bakhtiarian, A., Khavandgar, S., Dopamine receptor mechanism(s) and morphine tolerance in mice. J. Psychopharmacol. 16 (2002), 261–266.