Evaluation the effects of dextromethorphan and midazolam on morphine induced tolerance and dependence in mice

Pakistan Journal of Biological Sciences

Volumn 11, Issue 13, 2008, Pages 1690-1695

  Asl, Bohlul Habibi ^a   Hassanzadeh, Kambiz ^a   Khezri, Esmail ^a   Mohammadi, Sadollah ^a  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Dependence; Dextromethorphan; Midazolam; Morphine; Tolerance

Indexed keywords

MUS;

DEXTROMETHORPHAN; MIDAZOLAM; MORPHINE; NALOXONE;

ADDICTION; ANIMAL; ARTICLE; DRUG TOLERANCE; MALE; MOUSE;

ANIMALS; DEXTROMETHORPHAN; DRUG TOLERANCE; MALE; MICE; MIDAZOLAM; MORPHINE; NALOXONE; SUBSTANCE-RELATED DISORDERS;

EID: 54049126581     PISSN: 10288880     EISSN: 18125735     Source Type: Journal    
DOI: 10.3923/pjbs.2008.1690.1695     Document Type: Article

References (30)

1. Allen, R.M., A.L. Granger and L.A. Dykstra, 2002. Dextromethorphan potentiates the antinociceptive effects of morphine and the delta-opioid agonist SNC80 in squinel monkeys. J. Pharmacol. Exp. Ther., 300: 435-441.
2. Bartlett, S.E., T. Cramond and M.T. Smith, 1994. The excitatory effects of morphine-3-glucuronide are attenuated by LY274614, a competitive NMDA receptor antagonist and by midazolam, an agonist at the benzodiazepine site on the GABAA receptor complex. Life Sci., 54: 687-694.
3. Bossard, A.E., F. Guirimand, D. Fletcher, V. Gaude-Joindreau, M. Chauvin and D. Bouhassira, 2002. Interaction of a combination of morphine and ketamine on the nociceptive flexion reflex in human volunteers. Pain, 98: 47-57.
4. Cao, J.L., H.L. Ding, L.C. Zhang, S.M. Dung and Y.M. Zeng, 2002. Pretreatment with midazolam suppresses morphine withdrawal response in mice and rats. Acta Pharmacol. Sin., 23: 685-690.
5. Chan, S.L., C.C. Chou, C.S. Wong, C.C. Wu and P.L. Tao, 2002. Study the effect and mechanism of dextromethorphan on preventing the development of morphine tolerance and dependence in rats. J. Med. Sci., 22: 171-176.
6. Chevlen, E., 2000. Morphine with dextromethorphan: Conversion from other opioid analgesics. J. Pain Symptom Manage., 19: S42-S49.
7. Christensen, D., J.J. Idaanpan-Hiekkila and G. Guilboud, 1998. The antinociceptive effect of morphine and the glycine/NMDA receptor antagonist, (+)-HA966 in rat model of peripheral neuropathy. Br. J. Pharm., 125: 1641-1650.
8. Eric, J.N. and G.K. Aghajanian, 1997. Molecular and cellular basis of addiction. Science, 278: 58-63.
9. George, F.K., 2003. Neuroadaptive mechanisms of addiction: Study on the extended amigdala. Neuropsychopharmacology, 13: 442-452.
10. Habibi Asl, B. and K. Hassanzadeh, 2004. Effects of ketamine and midazolam on morphine induced dependence and tolerance in mice. DARU., 12: 101-105.
11. Habibi Asl, B., K. Hassanzadeh and S. Moosazadeh, 2005. Effects of ketamine and magnesium on morphine induced tolerance and dependence in mice. DARU., 13: 110-115.
12. Huang, E.Y., T.C. Liu and P.L. Tao, 2003. Co-administration of dextromethorphan with morphine attenuates morphine rewarding effect and related dopamine releases at the nucleus accumbens. Naunyn. Schmiedebergs Arch. Pharmacol., 368: 386-392.
13. Jaba, I.M., I. Luncanu and O.C. Mungiu, 2001. Opioid tolerance and dependence-pharmacological aspects. Rev. Med. Chir. Soc. Med. Nat. Iasi., 105: 444-450.
14. Johnson, S.W. and R.A. North, 1992. Opioids excite dopamine neurons by hyper polarization of local interneurons. J. Neurosci., 12: 483-488.
15. Kozela, E. and P. Popik, 2002. The effects of NMDA receptor antagonists on acute morphine antinociception in mice. Amino Acids, 23: 163-168.
16. Liu, J.G. and K. J. Anand, 2000. Protein kinases modulate the cellular adaptations associated with opioid tolerance and dependence. Brain Res. Rev., 38: 1-19.
17. Luger, T.J., I.H. Lorenz, C. Grabner-Weis and T. Hayashi, 1995. Effect of the NMDA-antagonist, MK 801, on benzodiazepine-opioid interactions at the spinal and supraspinal level in rats. Br. J. Pharmacol., 114: 1097-1103.
18. Manning, B.H., J. Mao, H. Frenk, D.D. Price and D.J. Mayer, 1996. Continuous co-administration of dextromethorphan or MK-801 with morphine: Attenuation of morphine dependence and naloxone-reversible attenuation of morphine tolerance. Pain, 67: 79-88.
19. Mao, J., D.D. Price, F.S. Caruso and D.J. Mayer, 1996. Oral administration of dextromethorphan prevents the development of morphine tolerance and dependence in rats. Pain, 67: 361-368.
20. Pepicelli, O., A. Brescia, E. Gherzi, M. Raiteri and E. Fedele, 2004. GABA(A), but not NMDA, receptors modulate in vivo NO-mediated cGMP synthesis in the rat cerebral cortex. Neuropharmacology, 46: 480-489.
21. Porreca, F., H.I. Mosberg, R. Hurst, V.J. Hruby and T.F. Burks, 1984. Roles of mu, delta and kappa opioid receptors in spinal and supraspinal mediation of gastrointestinal transit effects and hot-plate analgesia in the mouse. J. Pharmacol. Exp. Ther., 230: 341-348.
22. Rang, H.P., M.M. Dale and J.M. Ritter, 2005. Pharmacology. 1st Edn. Churchil livingstone, London, ISBN:0443072027 .
23. Rattan, A.K. and P. Sribanditmongkol, 1994. Effect of morphine-induced catalepsy, lethality and analgesia by a benzodiazepine receptor agonist midazolam in the rat. Pharmacol. Biochem. Behav., 48: 357-361.
24. Sheu, M.J., P. Sribanditmongkol, D.N. Santosa and G.A. Tejwani, 1995. Inhibition of morphine tolerance and dependence by diazepam and its relation to cyclic AMP levels in discrete rat brain regions and spinal cord. Brain Res., 675: 31-37.
25. Shoji, Y., J. Delfs and J.T. Williams, 1999. Presynaptic inhibition of GABA-B-mediated synaptic potentials in the VTA during morphine withdrawal. J. Neurosci., 19: 2347-2355.
26. Sinkkonen, S.T., A.M. Linden, E.R. Korpi and G. Wong, 2004. Selective reduction of gamma-aminobutyric acid type A receptor delta subunit mRNA levels by MK-801 in rat dentate gyrus. Neurosci. Lett., 364: 106-109.
27. Sivam, S.P. and I.K. Ho, 1985. GABA in morphine analgesia and tolerance. Life Sci., 37: 199-208.
28. Sribanditmongkol, P., M.J. Sheu and G.A. Tejwani, 1994. Inhibition of morphine tolerance and dependence by diazepam and its relation to the CNS Metenkephalinlevels. Brain Res., 645: 1-12.
29. Tejwani, G.A., A.K. Rattan, P. Sribanditmongkol, M.J. Sheu, J. Zuniga and J.S. McDonald, 1993. Inhibition of morphine-induced tolerance and dependence by a benzodiazepine receptor agonist midazolam in the rat. Anesth. Analg., 76: 1052-1060.
30. Tejwani, G.A., M.J. Sheu, P. Sribanditmongkol and A. Satyapriya, 1998. Inhibition of morphine tolerance and dependence by diazepam and its relation to mu-opioid receptors in the rat brain and spinal cord. Brain Res., 299: 305-312.