-
1
-
-
78049412888
-
Research funding. Sustaining the data and bioresource commons
-
Schofield PN, Eppig J, Huala E, de Angelis MH, Harvey M, Davidson D, Weaver T, Brown S, Smedley D, Rosenthal N, Schughart K, Aidinis V, Tocchini-Valentini G, Hancock JM. Research funding. Sustaining the data and bioresource commons. Science 2010;330:592-3.
-
(2010)
Science
, vol.330
, pp. 592-593
-
-
Schofield, P.N.1
Eppig, J.2
Huala, E.3
de Angelis, M.H.4
Harvey, M.5
Davidson, D.6
Weaver, T.7
Brown, S.8
Smedley, D.9
Rosenthal, N.10
Schughart, K.11
Aidinis, V.12
Tocchini-Valentini, G.13
Hancock, J.M.14
-
3
-
-
84861618843
-
Committee on the review of omics-based tests for predicting patient outcomes in clinical trials, Board of Health Care Services, Board on Health Sciences Policy, Institute of Medicine
-
Evolution of translational omics: lessons learned and the path forward. Washington DC: National Academies Press
-
Micheel CM, Nass SJ, Omenn GS, eds. Committee on the review of omics-based tests for predicting patient outcomes in clinical trials, Board of Health Care Services, Board on Health Sciences Policy, Institute of Medicine. Evolution of translational omics: lessons learned and the path forward. Washington DC: National Academies Press, 2012.
-
(2012)
-
-
Micheel, C.M.1
Nass, S.J.2
Omenn, G.S.3
-
4
-
-
84924365665
-
Open access to large scale datasets is needed to translate knowledge of cancer heterogeneity into better patient outcomes
-
Beck AH. Open access to large scale datasets is needed to translate knowledge of cancer heterogeneity into better patient outcomes. PLoS Med 2015;12: e1001794.
-
(2015)
PLoS Med
, vol.12
, pp. e1001794
-
-
Beck, A.H.1
-
5
-
-
79953704023
-
Predicting harms and benefits in translational trials: ethics, evidence and uncertainty
-
Kimmelman J, London AJ. Predicting harms and benefits in translational trials: ethics, evidence and uncertainty. PLoS Med 2011;8:e1001010.
-
(2011)
PLoS Med
, vol.8
, pp. e1001010
-
-
Kimmelman, J.1
London, A.J.2
-
7
-
-
79959882088
-
Ethical and practical challenges of sharing data from genome-wide association studies: the eMERGE Consortium experience
-
McGuire AL, Basford M, Dressler LG, Fullerton SM, Koenig B, Li R, McCarty CA, Ramos E, Smith ME, Sonkin CP, Waudby C, Wolf WA, Wright Clayton E. Ethical and practical challenges of sharing data from genome-wide association studies: the eMERGE Consortium experience. Genome Res 2011;21:1001-7.
-
(2011)
Genome Res
, vol.21
, pp. 1001-1007
-
-
McGuire, A.L.1
Basford, M.2
Dressler, L.G.3
Fullerton, S.M.4
Koenig, B.5
Li, R.6
McCarty, C.A.7
Ramos, E.8
Smith, M.E.9
Sonkin, C.P.10
Waudby, C.11
Wolf, W.A.12
Wright Clayton, E.13
-
8
-
-
84905981088
-
Creating value in health care through big data: opportunities and policy implications
-
Roski J, Bo-Linn GW, Andrews TA. Creating value in health care through big data: opportunities and policy implications. Health Aff (Millwood) 2014;33:1115-22.
-
(2014)
Health Aff (Millwood)
, vol.33
, pp. 1115-1122
-
-
Roski, J.1
Bo-Linn, G.W.2
Andrews, T.A.3
-
9
-
-
84892148591
-
Increasing value and reducing waste in biomedical research regulation and management
-
Al-Shahi Salman R, Beller E, Kagan J, Hemminki E, Phillips RS, Savulescu J, Macleod M, Wisely J, Chalmers I. Increasing value and reducing waste in biomedical research regulation and management. Lancet 2014;333:176-85.
-
(2014)
Lancet
, vol.333
, pp. 176-185
-
-
Al-Shahi Salman, R.1
Beller, E.2
Kagan, J.3
Hemminki, E.4
Phillips, R.S.5
Savulescu, J.6
Macleod, M.7
Wisely, J.8
Chalmers, I.9
-
10
-
-
84900415131
-
Ethics overload: impact of excessive ethical review on comorbidity research
-
Posselt M, Galletly C, de Crespigny C, Cairney I, Moss J, Liu D, Francis H, Kelly J, Procter N, Banders A. Ethics overload: impact of excessive ethical review on comorbidity research. Ment Health Subst Use 2014;7:184-94.
-
(2014)
Ment Health Subst Use
, vol.7
, pp. 184-194
-
-
Posselt, M.1
Galletly, C.2
de Crespigny, C.3
Cairney, I.4
Moss, J.5
Liu, D.6
Francis, H.7
Kelly, J.8
Procter, N.9
Banders, A.10
-
11
-
-
84873743291
-
Variation in ethics review of multi-site research initiatives
-
Caulfield T, Ries N, Barr G. Variation in ethics review of multi-site research initiatives. Amsterdam LF 2011;3:85-100.
-
(2011)
Amsterdam LF
, vol.3
, pp. 85-100
-
-
Caulfield, T.1
Ries, N.2
Barr, G.3
-
12
-
-
79954508843
-
A systematic review of the empirical literature evaluating IRBs: what we know and what we still need to learn
-
Abbott L, Grady C. A systematic review of the empirical literature evaluating IRBs: what we know and what we still need to learn. J Empir Res Hum Res Ethics 2011;6:3-19.
-
(2011)
J Empir Res Hum Res Ethics
, vol.6
, pp. 3-19
-
-
Abbott, L.1
Grady, C.2
-
13
-
-
84893521562
-
Institutional review boards: what's old? What's new? What needs to change?
-
Kotsis SV, Chung KC. Institutional review boards: what's old? What's new? What needs to change? Plast Reconstr Surg 2014;133:439-45.
-
(2014)
Plast Reconstr Surg
, vol.133
, pp. 439-445
-
-
Kotsis, S.V.1
Chung, K.C.2
-
14
-
-
84864950992
-
Ethics application protocols for multicentre clinical studies in Canada: a paediatric rheumatology experience
-
Matheson L, Huber AM, Warner A, Rosenberg AM. Ethics application protocols for multicentre clinical studies in Canada: a paediatric rheumatology experience. Paediatr Child Health 2012;17:313-16.
-
(2012)
Paediatr Child Health
, vol.17
, pp. 313-316
-
-
Matheson, L.1
Huber, A.M.2
Warner, A.3
Rosenberg, A.M.4
-
15
-
-
84973286029
-
Draft Policy on the Use of a Single Institutional Review Board for Multi-Site Research
-
National Institutes of Health (NIH). Draft Policy on the Use of a Single Institutional Review Board for Multi-Site Research. http://grants.nih.gov/grants/ guide/notice-files/NOT-OD-15-026.html
-
-
-
-
16
-
-
84940026159
-
Cadre de référence des établissements publics du réseau de la santé et des services sociaux pour l'autorisation d'une recherche menée dans plus d'un établissement
-
Universities are excluded i.e. Research led by University professors will have to undergo University REB review as well
-
Quebec Ministry of Health and Social Services. Cadre de référence des établissements publics du réseau de la santé et des services sociaux pour l'autorisation d'une recherche menée dans plus d'un établissement. 2014. http://ethique.msss.gouv.qc.ca/ fileadmin/documents/mecanismes_multicentrique_ 2014/Cadre_de_reference:Novembre_2014.pdf. Universities are excluded i.e. Research led by University professors will have to undergo University REB review as well.
-
(2014)
-
-
-
17
-
-
33645754988
-
Ethics review of multi-centre clinical trials in Canada
-
Enzle ME, Schmaltz R. Ethics review of multi-centre clinical trials in Canada. Health Law Review 2005;13:51-7.
-
(2005)
Health Law Review
, vol.13
, pp. 51-57
-
-
Enzle, M.E.1
Schmaltz, R.2
-
18
-
-
84908205733
-
2014 report on the milestones for the US national plan to address Alzheimer's disease
-
Alzheimer's Association National Plan Milestone WorkgroupFargo KN, Aisen P, Albert M, Au R, Corrada MM, DeKosky S, Drachman D, Fillit H, Gitlin L, Haas M, Herrup K, Kawas C, Khachaturian AS, Khachaturian ZS, Klunk W, Knopman D, Kukull WA, Lamb B, Logsdon RG, Maruff P, Mesulam M, Mobley W, Mohs R, Morgan D, Nixon RA, Paul S, Petersen R, Plassman B, Potter W, Reiman E, Reisberg B, Sano M, Schindler R, Schneider LS, Snyder PJ, Sperling RA, Yaffe K, Bain LJ, Thies WH, Carrillo MC. 2014 report on the milestones for the US national plan to address Alzheimer's disease. Alzheimers Dement 2014;10:S430-52.
-
(2014)
Alzheimers Dement
, vol.10
, pp. S430-S452
-
-
Alzheimer's Association National Plan Milestone WorkgroupFargo, K.N.1
Aisen, P.2
Albert, M.3
Au, R.4
Corrada, M.M.5
DeKosky, S.6
Drachman, D.7
Fillit, H.8
Gitlin, L.9
Haas, M.10
Herrup, K.11
Kawas, C.12
Khachaturian, A.S.13
Khachaturian, Z.S.14
Klunk, W.15
Knopman, D.16
Kukull, W.A.17
Lamb, B.18
Logsdon, R.G.19
Maruff, P.20
Mesulam, M.21
Mobley, W.22
Mohs, R.23
Morgan, D.24
Nixon, R.A.25
Paul, S.26
Petersen, R.27
Plassman, B.28
Potter, W.29
Reiman, E.30
Reisberg, B.31
Sano, M.32
Schindler, R.33
Schneider, L.S.34
Snyder, P.J.35
Sperling, R.A.36
Yaffe, K.37
Bain, L.J.38
Thies, W.H.39
Carrillo, M.C.40
more..
-
19
-
-
84940081663
-
Despite having a national guideline for the ethical conduct of research involving human subjects, it is still under the legal remit of the provinces to determine the comprehensiveness of ethics review
-
The Constitution Act, 30 & 31 Vict, c 3, section 92
-
Despite having a national guideline for the ethical conduct of research involving human subjects, it is still under the legal remit of the provinces to determine the comprehensiveness of ethics review. The Constitution Act, 1867, 30 & 31 Vict, c 3, section 92.
-
(1867)
-
-
-
20
-
-
84937030792
-
The Tri Council Policy Statement: Ethical Conduct for Research Involving Humans
-
CIHR, NSERC and SSHRC, The Tri Council Policy Statement: Ethical Conduct for Research Involving Humans. 2014. http://www.pre.ethics.gc.ca/pdf/eng/ tcps2-2014/TCPS_2_FINAL_Web.pdf
-
(2014)
-
-
-
21
-
-
84973353490
-
MICYRN Vision and Mission
-
Maternal, Infant, Child and Youth Research Network. MICYRN Vision and Mission. http://www.micyrn.ca/ AboutUs.html
-
-
-
-
22
-
-
60149102060
-
Size matters: just how big is BIG?
-
Burton P, Hansell AL, Fortier I, Manolio TA, Khoury MJ, Little J, Elliott P. Size matters: just how big is BIG? Int J Epidemiol 2009;38:263-73.
-
(2009)
Int J Epidemiol
, vol.38
, pp. 263-273
-
-
Burton, P.1
Hansell, A.L.2
Fortier, I.3
Manolio, T.A.4
Khoury, M.J.5
Little, J.6
Elliott, P.7
-
23
-
-
84940050721
-
There will be sharing: population biobanks, the duty to inform and the limitations of the individualistic conception of autonomy
-
Zawati MH. There will be sharing: population biobanks, the duty to inform and the limitations of the individualistic conception of autonomy. Health Law J 2014;21:97-140.
-
(2014)
Health Law J
, vol.21
, pp. 97-140
-
-
Zawati, M.H.1
-
24
-
-
84929042712
-
From the principles of genomic data sharing to the practices of data access committees
-
Shabani M, Knoppers B, Borry P. From the principles of genomic data sharing to the practices of data access committees. EMBO Mol Med 2015;7:507-9.
-
(2015)
EMBO Mol Med
, vol.7
, pp. 507-509
-
-
Shabani, M.1
Knoppers, B.2
Borry, P.3
-
25
-
-
84973322755
-
Canadian Partnership for Tomorrow Project Website
-
Canadian Partnership for Tomorrow Project. Canadian Partnership for Tomorrow Project Website. http://www.partnershipfortomorrow.ca/cptp/portal/ WhyHelp?_afrLoop=932393947691000&lang=en&_ afrWindowMode=0&_adf.ctrl-state=10s253znr3_25
-
-
-
-
26
-
-
84901309716
-
Big data, open science and the brain: lessons learned from genomics
-
Choudhury S, Fishman JR, McGowan ML, Juengst ET. Big data, open science and the brain: lessons learned from genomics. Front Hum Neurosci 2014;8:239.
-
(2014)
Front Hum Neurosci
, vol.8
, pp. 239
-
-
Choudhury, S.1
Fishman, J.R.2
McGowan, M.L.3
Juengst, E.T.4
-
27
-
-
84901432298
-
Collaborative biomedicine in the age of big data: the case of cancer
-
Shaikh AR, Butte AJ, Schully SD, Dalton WS, Khoury MJ, Hesse BW. Collaborative biomedicine in the age of big data: the case of cancer. J Med Internet Res 2014;16:e101.
-
(2014)
J Med Internet Res
, vol.16
, pp. e101
-
-
Shaikh, A.R.1
Butte, A.J.2
Schully, S.D.3
Dalton, W.S.4
Khoury, M.J.5
Hesse, B.W.6
-
28
-
-
84973330879
-
Global Alliance for Genomics & Health Website
-
Framework for Responsible Sharing of Genomic and Health-Related Data. Global Alliance for Genomics & Health Website. 2014. http://genomicsandhealth.org/ about-the-global-alliance/key-documents/frameworkresponsible- sharing-genomic-and-health-related-data
-
(2014)
-
-
-
29
-
-
84888093815
-
An ethics safe harbor for international genomics research?
-
Dove ES, Knoppers BM, Zawati MH. An ethics safe harbor for international genomics research? Genome Med 2013;5:99.
-
(2013)
Genome Med
, vol.5
, pp. 99
-
-
Dove, E.S.1
Knoppers, B.M.2
Zawati, M.H.3
-
30
-
-
84924633598
-
Building a data sharing model for global genomic research
-
Kosseim P, Dove ES, Baggaley C, Meslin EM, Cate FH, Kaye J, Harris JR, Knoppers BM. Building a data sharing model for global genomic research. Genome Biol 2014;15:430.
-
(2014)
Genome Biol
, vol.15
, pp. 430
-
-
Kosseim, P.1
Dove, E.S.2
Baggaley, C.3
Meslin, E.M.4
Cate, F.H.5
Kaye, J.6
Harris, J.R.7
Knoppers, B.M.8
-
31
-
-
84904118648
-
A human rights approach to an international code of conduct for genomic and clinical data sharing
-
Knoppers BM, Harris JR, Budin-Ljosne I, Dove ES. A human rights approach to an international code of conduct for genomic and clinical data sharing. Hum Genet 2014;133:895-903.
-
(2014)
Hum Genet
, vol.133
, pp. 895-903
-
-
Knoppers, B.M.1
Harris, J.R.2
Budin-Ljosne, I.3
Dove, E.S.4
-
32
-
-
84927168314
-
The need to redefine genomic data sharing: a focus on data accessibility
-
van Schaik TA, Kovalevskaya NV, Protopapas E, Wahid H, Nielsen FGG. The need to redefine genomic data sharing: a focus on data accessibility. Appl Transl Genomics 2014;3:100-4.
-
(2014)
Appl Transl Genomics
, vol.3
, pp. 100-104
-
-
van Schaik, T.A.1
Kovalevskaya, N.V.2
Protopapas, E.3
Wahid, H.4
Nielsen, F.G.G.5
-
33
-
-
84864628956
-
Data sharing in the post-genomic world: the experience of the International Cancer Genome Consortium (ICGC) Data Access Compliance Office (DACO)
-
Joly Y, Dove ES, Knoppers BM, Bobrow M, Chalmers D. Data sharing in the post-genomic world: the experience of the International Cancer Genome Consortium (ICGC) Data Access Compliance Office (DACO). PLoS Comput Biol 2012;8:e1002549.
-
(2012)
PLoS Comput Biol
, vol.8
, pp. e1002549
-
-
Joly, Y.1
Dove, E.S.2
Knoppers, B.M.3
Bobrow, M.4
Chalmers, D.5
-
34
-
-
80755139422
-
To share or not to share: a randomized trial of consent for data sharing in genome research
-
McGuire AL, Oliver JM, Slashinski MJ, Graves JL, Wang T, Kelly PA, Fisher W, Lau CC, Goss J, Okcu M, Treadwell-Deering D, Goldman AM, Noebels JL, Hilsenbeck SG. To share or not to share: a randomized trial of consent for data sharing in genome research. Genet Med 2011;13:948-55.
-
(2011)
Genet Med
, vol.13
, pp. 948-955
-
-
McGuire, A.L.1
Oliver, J.M.2
Slashinski, M.J.3
Graves, J.L.4
Wang, T.5
Kelly, P.A.6
Fisher, W.7
Lau, C.C.8
Goss, J.9
Okcu, M.10
Treadwell-Deering, D.11
Goldman, A.M.12
Noebels, J.L.13
Hilsenbeck, S.G.14
|