Anti-apoa-1 auto-antibodies increase mouse atherosclerotic plaque vulnerability, myocardial necrosis and mortality triggering TLR2 and TLR4

Thrombosis and Haemostasis

Volumn 114, Issue 2, 2015, Pages 410-422

  Montecucco, Fabrizio ^a,b,c   Braunersreuther, Vincent ^b   Burger, Fabienne ^b   Lenglet, Sébastien ^b   Pelli, Graziano ^b   Carbone, Federico ^a,b   Fraga Silva, Rodrigo ^d   Stergiopulos, Nikolaos ^d   Monaco, Claudia ^e   Mueller, Christian ^f   Pagano, Sabrina ^c   Dallegri, Franco ^a   Mach, François ^b   Vuilleumier, Nicolas ^c  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^d EPFL   (Switzerland)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f UNIVERSITY HOSPITAL BASEL   (Switzerland)

Author keywords

Acute myocardial infarction; Antibody; Atherogenesis; Mortality

Indexed keywords

APOLIPOPROTEIN A1; AUTOANTIBODY; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TROPONIN I; APOLIPOPROTEIN E; COLLAGEN; IMMUNOGLOBULIN G; LIPID; TLR2 PROTEIN, MOUSE; TLR4 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; BODY WEIGHT; CONTROLLED STUDY; ELECTROCARDIOGRAPHY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENOTYPING TECHNIQUE; HEART MUSCLE NECROSIS; HEMATOLOGICAL PARAMETERS; HISTOCHEMISTRY; MACROPHAGE; MORTALITY; MOUSE; NEUTROPHIL; NONHUMAN; PASSIVE IMMUNIZATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TELEMETRY; THORACOABDOMINAL AORTA ANEURYSM; ADVERSE EFFECTS; ANIMAL; ANTAGONISTS AND INHIBITORS; AORTA DISEASE; BLOOD; CARDIAC MUSCLE; DEFICIENCY; DISEASE PREDISPOSITION; GENETICS; IMMUNOLOGY; KNOCKOUT MOUSE; MALE; METABOLISM; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; NECROSIS; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; AORTIC DISEASES; APOLIPOPROTEIN A-I; APOLIPOPROTEINS E; AUTOANTIBODIES; COLLAGEN; DISEASE SUSCEPTIBILITY; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN G; LIPIDS; MALE; MICE; MICE, KNOCKOUT; MYOCARDIAL INFARCTION; MYOCARDIAL ISCHEMIA; MYOCARDIUM; NECROSIS; PLAQUE, ATHEROSCLEROTIC; SIGNAL TRANSDUCTION; TELEMETRY; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TROPONIN I;

EID: 84940035193     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH14-12-1039     Document Type: Article

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