Blocking TLR2 activity diminishes and stabilizes advanced atherosclerotic lesions in apolipoprotein E-deficient mice

Acta Pharmacologica Sinica

Volumn 34, Issue 8, 2013, Pages 1025-1035

  Wang, Xiao Xing ^a   Lv, Xiao Xi ^a   Wang, Jia Ping ^a   Yan, Hui Min ^a   Wang, Zi Yan ^a   Liu, Han Zhi ^a   Fu, Xiao Ming ^a   Hu, Zhuo Wei ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

apolipoprotein E deficient (Apoe ) mice; apoptosis; atherosclerosis; cardiovascular disease; ER stress; inflammation; macrophage; toll like receptor 2

Indexed keywords

APOLIPOPROTEIN E; CYTOKINE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; NEUTRALIZING ANTIBODY; STAT3 PROTEIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 2 NEUTRALIZING ANTIBODY; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTERY; ARTICLE; ATHEROSCLEROSIS; BRACHIOCEPHALIC TRUNK; CHOLESTEROL DIET; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; GENETIC MANIPULATION; LIPID BLOOD LEVEL; MACROPHAGE; MOUSE; NONHUMAN;

ANIMALS; ANTIBODIES, NEUTRALIZING; APOLIPOPROTEINS E; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLAQUE, ATHEROSCLEROTIC; RANDOM ALLOCATION; TOLL-LIKE RECEPTOR 2;

EID: 84882306818     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2013.75     Document Type: Article

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