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Volumn 34, Issue 5, 2015, Pages 863-876

A systematic review of matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry compared to routine microbiological methods for the time taken to identify microbial organisms from positive blood cultures

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD; COMPARATIVE STUDY; ECONOMICS; HEALTH CARE COST; HUMAN; LENGTH OF STAY; MASS SPECTROMETRY; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; PROCEDURES; SEPSIS; TIME;

EID: 84939957979     PISSN: 09349723     EISSN: 14354373     Source Type: Journal    
DOI: 10.1007/s10096-015-2322-0     Document Type: Review
Times cited : (46)

References (40)
  • 1
    • 84977802049 scopus 로고    scopus 로고
    • CDC/NHSN surveillance definitions for specific types of infections
    • Centers for Disease Control and Prevention (CDC) (2014) CDC/NHSN surveillance definitions for specific types of infections. CDC, 63 pp
    • (2014) CDC , pp. 63
  • 2
    • 65649140523 scopus 로고    scopus 로고
    • The clinical importance of microbiological findings in the diagnosis and management of bloodstream infections
    • PID: 19374579
    • Seifert H (2009) The clinical importance of microbiological findings in the diagnosis and management of bloodstream infections. Clin Infect Dis 48(Suppl 4):S238–S245
    • (2009) Clin Infect Dis , vol.48 , pp. 238-245
    • Seifert, H.1
  • 3
    • 26444523446 scopus 로고    scopus 로고
    • Bacteremias: a leading cause of death
    • PID: 16216646
    • Bearman GML, Wenzel RP (2005) Bacteremias: a leading cause of death. Arch Med Res 36(6):646–659
    • (2005) Arch Med Res , vol.36 , Issue.6 , pp. 646-659
    • Bearman, G.M.L.1    Wenzel, R.P.2
  • 4
    • 84876803444 scopus 로고    scopus 로고
    • Overall burden of bloodstream infection and nosocomial bloodstream infection in North America and Europe
    • COI: 1:STN:280:DC%2BC3svksV2ksw%3D%3D, PID: 23473333
    • Goto M, Al-Hasan MN (2013) Overall burden of bloodstream infection and nosocomial bloodstream infection in North America and Europe. Clin Microbiol Infect 19(6):501–509
    • (2013) Clin Microbiol Infect , vol.19 , Issue.6 , pp. 501-509
    • Goto, M.1    Al-Hasan, M.N.2
  • 6
    • 34748886076 scopus 로고    scopus 로고
    • Burden of community-onset bloodstream infection: a population-based assessment
    • COI: 1:STN:280:DC%2BD2svls1Sjsg%3D%3D, PID: 17156500
    • Laupland KB, Gregson DB, Flemons WW, Hawkins D, Ross T, Church DL (2007) Burden of community-onset bloodstream infection: a population-based assessment. Epidemiol Infect 135(6):1037–1042
    • (2007) Epidemiol Infect , vol.135 , Issue.6 , pp. 1037-1042
    • Laupland, K.B.1    Gregson, D.B.2    Flemons, W.W.3    Hawkins, D.4    Ross, T.5    Church, D.L.6
  • 7
    • 57149127670 scopus 로고    scopus 로고
    • Cost of bloodstream infections
    • Kilgore M, Brossette S (2008) Cost of bloodstream infections. Am J Infect Control 36(10):S172.e1–S172.e3
    • (2008) Am J Infect Control , vol.36 , Issue.10 , pp. 1-3
    • Kilgore, M.1    Brossette, S.2
  • 10
    • 84977787956 scopus 로고    scopus 로고
    • Prevention and control of healthcare-associated infections in primary and community care
    • National Institute for Health and Care Excellence (NICE) (2012) Prevention and control of healthcare-associated infections in primary and community care. Available online at: http://www.nice.org.uk/guidance/cg139/resources/guidance-infection-pdf. Accessed 25 July 2014
    • (2012) Available online at:
  • 11
    • 68049133326 scopus 로고    scopus 로고
    • Bloodstream infection in the ICU
    • PID: 19665083
    • Vallés J, Ferrer R (2009) Bloodstream infection in the ICU. Infect Dis Clin North Am 23(3):557–569
    • (2009) Infect Dis Clin North Am , vol.23 , Issue.3 , pp. 557-569
    • Vallés, J.1    Ferrer, R.2
  • 12
    • 84977770789 scopus 로고    scopus 로고
    • MALDI-TOF MS: a new laboratory option for the diagnosis of clinical infections
    • Tonolla M, Benagli C, Rossi V, Fragoso C, Petrini O (2010) MALDI-TOF MS: a new laboratory option for the diagnosis of clinical infections. Pipette 3:6–10
    • (2010) Pipette , vol.3 , pp. 6-10
    • Tonolla, M.1    Benagli, C.2    Rossi, V.3    Fragoso, C.4    Petrini, O.5
  • 13
    • 80051677037 scopus 로고    scopus 로고
    • Identification of bacteria in blood culture broths using matrix-assisted laser desorption–ionization Sepsityper™ and time of flight mass spectrometry
    • COI: 1:CAS:528:DC%2BC3MXhtFKmsLzF, PID: 21858058
    • Kok J, Thomas LC, Olma T, Chen SC, Iredell JR (2011) Identification of bacteria in blood culture broths using matrix-assisted laser desorption–ionization Sepsityper™ and time of flight mass spectrometry. PLoS One 6(8):e23285
    • (2011) PLoS One , vol.6 , Issue.8 , pp. 23285
    • Kok, J.1    Thomas, L.C.2    Olma, T.3    Chen, S.C.4    Iredell, J.R.5
  • 16
    • 84861657004 scopus 로고    scopus 로고
    • Bench-to-bedside review: rapid molecular diagnostics for bloodstream infection—a new frontier?
    • PID: 22647543
    • Afshari A, Schrenzel J, Ieven M, Harbarth S (2012) Bench-to-bedside review: rapid molecular diagnostics for bloodstream infection—a new frontier? Crit Care 16(3):222
    • (2012) Crit Care , vol.16 , Issue.3 , pp. 222
    • Afshari, A.1    Schrenzel, J.2    Ieven, M.3    Harbarth, S.4
  • 17
    • 79953869376 scopus 로고    scopus 로고
    • Performance and cost analysis of matrix-assisted laser desorption ionization–time of flight mass spectrometry for routine identification of yeast
    • COI: 1:CAS:528:DC%2BC3MXhtFKrtL3O, PID: 21270234
    • Dhiman N, Hall L, Wohlfiel SL, Buckwalter SP, Wengenack NL (2011) Performance and cost analysis of matrix-assisted laser desorption ionization–time of flight mass spectrometry for routine identification of yeast. J Clin Microbiol 49(4):1614–1616
    • (2011) J Clin Microbiol , vol.49 , Issue.4 , pp. 1614-1616
    • Dhiman, N.1    Hall, L.2    Wohlfiel, S.L.3    Buckwalter, S.P.4    Wengenack, N.L.5
  • 18
    • 84977773187 scopus 로고    scopus 로고
    • MALDI-TOF mass spectrometry for bacterial species identification: a review of diagnostic accuracy and clinical and cost-effectiveness
    • Canadian Agency for Drugs and Technologies in Health (2011) MALDI-TOF mass spectrometry for bacterial species identification: a review of diagnostic accuracy and clinical and cost-effectiveness. Rapid Response Rep. Available online at: http://www.cadth.ca/en/publication/2936
    • (2011) Rapid Response Rep
  • 19
  • 23
    • 84856206216 scopus 로고    scopus 로고
    • Comparison of the MALDI Biotyper system using Sepsityper specimen processing to routine microbiological methods for identification of bacteria from positive blood culture bottles
    • COI: 1:CAS:528:DC%2BC38XktVKhtb4%3D, PID: 22162549
    • Buchan BW, Riebe KM, Ledeboer NA (2012) Comparison of the MALDI Biotyper system using Sepsityper specimen processing to routine microbiological methods for identification of bacteria from positive blood culture bottles. J Clin Microbiol 50(2):346–352
    • (2012) J Clin Microbiol , vol.50 , Issue.2 , pp. 346-352
    • Buchan, B.W.1    Riebe, K.M.2    Ledeboer, N.A.3
  • 24
    • 84880720602 scopus 로고    scopus 로고
    • Rapid identification of pathogens directly from blood culture bottles by Bruker matrix-assisted laser desorption laser ionization–time of flight mass spectrometry versus routine methods
    • COI: 1:CAS:528:DC%2BC3sXosVOgtr8%3D, PID: 23726652
    • Jamal W, Saleem R, Rotimi VO (2013) Rapid identification of pathogens directly from blood culture bottles by Bruker matrix-assisted laser desorption laser ionization–time of flight mass spectrometry versus routine methods. Diagn Microbiol Infect Dis 76(4):404–408
    • (2013) Diagn Microbiol Infect Dis , vol.76 , Issue.4 , pp. 404-408
    • Jamal, W.1    Saleem, R.2    Rotimi, V.O.3
  • 25
    • 84866450171 scopus 로고    scopus 로고
    • Identification of blood culture isolates directly from positive blood cultures by use of matrix-assisted laser desorption ionization–time of flight mass spectrometry and a commercial extraction system: analysis of performance, cost, and turnaround time
    • PID: 22875888
    • Lagacé-Wiens PRS, Adam HJ, Karlowsky JA, Nichol KA, Pang PF, Guenther J, Webb AA, Miller C, Alfa MJ (2012) Identification of blood culture isolates directly from positive blood cultures by use of matrix-assisted laser desorption ionization–time of flight mass spectrometry and a commercial extraction system: analysis of performance, cost, and turnaround time. J Clin Microbiol 50(10):3324–3328
    • (2012) J Clin Microbiol , vol.50 , Issue.10 , pp. 3324-3328
    • Lagacé-Wiens, P.R.S.1    Adam, H.J.2    Karlowsky, J.A.3    Nichol, K.A.4    Pang, P.F.5    Guenther, J.6    Webb, A.A.7    Miller, C.8    Alfa, M.J.9
  • 28
    • 84895884401 scopus 로고    scopus 로고
    • Same day identification and full panel antimicrobial susceptibility testing of bacteria from positive blood culture bottles made possible by a combined lysis-filtration method with MALDI-TOF VITEK mass spectrometry and the VITEK2 system
    • PID: 24551067
    • Machen A, Drake T, Wang YF (2014) Same day identification and full panel antimicrobial susceptibility testing of bacteria from positive blood culture bottles made possible by a combined lysis-filtration method with MALDI-TOF VITEK mass spectrometry and the VITEK2 system. PLoS One 9(2):e87870
    • (2014) PLoS One , vol.9 , Issue.2 , pp. 87870
    • Machen, A.1    Drake, T.2    Wang, Y.F.3
  • 29
    • 84887120883 scopus 로고    scopus 로고
    • Work flow analysis of around-the-clock processing of blood culture samples and integrated MALDI-TOF mass spectrometry analysis for the diagnosis of bloodstream infections
    • COI: 1:CAS:528:DC%2BC3sXhslGht7vF, PID: 23881934
    • Schneiderhan W, Grundt A, Wörner S, Findeisen P, Neumaier M (2013) Work flow analysis of around-the-clock processing of blood culture samples and integrated MALDI-TOF mass spectrometry analysis for the diagnosis of bloodstream infections. Clin Chem 59(11):1649–1656
    • (2013) Clin Chem , vol.59 , Issue.11 , pp. 1649-1656
    • Schneiderhan, W.1    Grundt, A.2    Wörner, S.3    Findeisen, P.4    Neumaier, M.5
  • 30
    • 79955661694 scopus 로고    scopus 로고
    • Acceptance criteria for identification results of Gram-negative rods by mass spectrometry
    • PID: 21233293
    • De Bel A, Wybo I, Vandoorslaer K, Rosseel P, Lauwers S, Piérard D (2011) Acceptance criteria for identification results of Gram-negative rods by mass spectrometry. J Med Microbiol 60(Pt 5):684–686
    • (2011) J Med Microbiol , vol.60 , pp. 684-686
    • De Bel, A.1    Wybo, I.2    Vandoorslaer, K.3    Rosseel, P.4    Lauwers, S.5    Piérard, D.6
  • 31
    • 84866409862 scopus 로고    scopus 로고
    • Comparison of an in-house method and the commercial Sepsityper™ kit for bacterial identification directly from positive blood culture broths by matrix-assisted laser desorption–ionisation time-of-flight mass spectrometry
    • COI: 1:STN:280:DC%2BC38vktlOhsQ%3D%3D, PID: 22367290
    • Martiny D, Dediste A, Vandenberg O (2012) Comparison of an in-house method and the commercial Sepsityper™ kit for bacterial identification directly from positive blood culture broths by matrix-assisted laser desorption–ionisation time-of-flight mass spectrometry. Eur J Clin Microbiol Infect Dis 31(9):2269–2281
    • (2012) Eur J Clin Microbiol Infect Dis , vol.31 , Issue.9 , pp. 2269-2281
    • Martiny, D.1    Dediste, A.2    Vandenberg, O.3
  • 32
    • 84886911636 scopus 로고    scopus 로고
    • Impact of rapid organism identification via matrix-assisted laser desorption/ionization time-of-flight combined with antimicrobial stewardship team intervention in adult patients with bacteremia and candidemia
    • COI: 1:CAS:528:DC%2BC3sXhs1Wlt7zK, PID: 23899684
    • Huang AM, Newton D, Kunapuli A, Gandhi TN, Washer LL, Isip J, Collins CD, Nagel JL (2013) Impact of rapid organism identification via matrix-assisted laser desorption/ionization time-of-flight combined with antimicrobial stewardship team intervention in adult patients with bacteremia and candidemia. Clin Infect Dis 57(9):1237–1245
    • (2013) Clin Infect Dis , vol.57 , Issue.9 , pp. 1237-1245
    • Huang, A.M.1    Newton, D.2    Kunapuli, A.3    Gandhi, T.N.4    Washer, L.L.5    Isip, J.6    Collins, C.D.7    Nagel, J.L.8
  • 34
    • 84858408842 scopus 로고    scopus 로고
    • Direct matrix-assisted laser desorption ionization time-of-flight mass spectrometry improves appropriateness of antibiotic treatment of bacteremia
    • COI: 1:CAS:528:DC%2BC38XkvVagtb0%3D, PID: 22438880
    • Vlek ALM, Bonten MJM, Boel CHE (2012) Direct matrix-assisted laser desorption ionization time-of-flight mass spectrometry improves appropriateness of antibiotic treatment of bacteremia. PLoS One 7(3):e32589
    • (2012) PLoS One , vol.7 , Issue.3 , pp. 32589
    • Vlek, A.L.M.1    Bonten, M.J.M.2    Boel, C.H.E.3
  • 35
    • 84977784118 scopus 로고    scopus 로고
    • New test system identifies 193 different yeasts and bacteria known to cause illness
    • U.S. Food and Drug Administration (FDA) (2013) New test system identifies 193 different yeasts and bacteria known to cause illness. Available online at: http://www.fda.gov/newsevents/newsroom/pressannouncements/ucm365907.htm. Accessed 28 May 2014
    • (2013) Available online at:
    • Food, U.S.1    Administration, D.2
  • 36
    • 84878496270 scopus 로고    scopus 로고
    • Direct bacterial identification in positive blood cultures by use of two commercial matrix-assisted laser desorption ionization–time of flight mass spectrometry systems
    • COI: 1:CAS:528:DC%2BC3sXpvVeisrg%3D, PID: 23515548
    • Chen JHK, Ho P-L, Kwan GSW, She KKK, Siu GKH, Cheng VCC, Yuen K-Y, Yam W-C (2013) Direct bacterial identification in positive blood cultures by use of two commercial matrix-assisted laser desorption ionization–time of flight mass spectrometry systems. J Clin Microbiol 51(6):1733–1739
    • (2013) J Clin Microbiol , vol.51 , Issue.6 , pp. 1733-1739
    • Chen, J.H.K.1    Ho, P.-L.2    Kwan, G.S.W.3    She, K.K.K.4    Siu, G.K.H.5    Cheng, V.C.C.6    Yuen, K.-Y.7    Yam, W.-C.8
  • 37
    • 77950462078 scopus 로고    scopus 로고
    • Comparison of two matrix-assisted laser desorption ionization-time of flight mass spectrometry methods with conventional phenotypic identification for routine identification of bacteria to the species level
    • COI: 1:CAS:528:DC%2BC3cXmt1Kgtbw%3D, PID: 20164271
    • Cherkaoui A, Hibbs J, Emonet S, Tangomo M, Girard M, Francois P, Schrenzel J (2010) Comparison of two matrix-assisted laser desorption ionization-time of flight mass spectrometry methods with conventional phenotypic identification for routine identification of bacteria to the species level. J Clin Microbiol 48(4):1169–1175
    • (2010) J Clin Microbiol , vol.48 , Issue.4 , pp. 1169-1175
    • Cherkaoui, A.1    Hibbs, J.2    Emonet, S.3    Tangomo, M.4    Girard, M.5    Francois, P.6    Schrenzel, J.7
  • 38
    • 79960965903 scopus 로고    scopus 로고
    • Utility of matrix-assisted laser desorption ionization–time of flight mass spectrometry following introduction for routine laboratory bacterial identification
    • PID: 21632894
    • Neville SA, LeCordier A, Ziochos H, Chater MJ, Gosbell IB, Maley MW, van Hal SJ (2011) Utility of matrix-assisted laser desorption ionization–time of flight mass spectrometry following introduction for routine laboratory bacterial identification. J Clin Microbiol 49(8):2980–2984
    • (2011) J Clin Microbiol , vol.49 , Issue.8 , pp. 2980-2984
    • Neville, S.A.1    LeCordier, A.2    Ziochos, H.3    Chater, M.J.4    Gosbell, I.B.5    Maley, M.W.6    van Hal, S.J.7
  • 39
    • 67651108596 scopus 로고    scopus 로고
    • Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
    • COI: 1:CAS:528:DC%2BD1MXhtVOmsrzM, PID: 19583519
    • Seng P, Drancourt M, Gouriet F, La Scola B, Fournier P-E, Rolain JM, Raoult D (2009) Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Clin Infect Dis 49(4):543–551
    • (2009) Clin Infect Dis , vol.49 , Issue.4 , pp. 543-551
    • Seng, P.1    Drancourt, M.2    Gouriet, F.3    La Scola, B.4    Fournier, P.-E.5    Rolain, J.M.6    Raoult, D.7


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