-
1
-
-
84877999567
-
Green factories for biopharmaceuticals
-
S. Melnik, and E. Stoger Green factories for biopharmaceuticals Curr Med Chem 20 2013 1038 1046
-
(2013)
Curr Med Chem
, vol.20
, pp. 1038-1046
-
-
Melnik, S.1
Stoger, E.2
-
2
-
-
84881354730
-
Commercial aspects of pharmaceutical protein production in plants
-
R. Fischer, S. Schillberg, J.F. Buyel, and R.M. Twyman Commercial aspects of pharmaceutical protein production in plants Curr Pharm Des 19 2013 5471 5477
-
(2013)
Curr Pharm des
, vol.19
, pp. 5471-5477
-
-
Fischer, R.1
Schillberg, S.2
Buyel, J.F.3
Twyman, R.M.4
-
3
-
-
84864941692
-
Green factory: Plants as bioproduction platforms for recombinant proteins
-
J.F. Xu, M.C. Dolan, G. Medrano, C.L. Cramer, and P.J. Weathers Green factory: plants as bioproduction platforms for recombinant proteins Biotechnol Adv 30 2012 1171 1184
-
(2012)
Biotechnol Adv
, vol.30
, pp. 1171-1184
-
-
Xu, J.F.1
Dolan, M.C.2
Medrano, G.3
Cramer, C.L.4
Weathers, P.J.5
-
4
-
-
84908116847
-
A Phase 3, multicenter, open-label, switchover trial to assess the safety and efficacy of taliglucerase alfa, a plant cell-expressed recombinant human glucocerebrosidase, in adult and pediatric patients with Gaucher disease previously treated with imiglucerase
-
G.M. Pastores, M. Petakov, P. Giraldo, H. Rosenbaum, J. Szer, and P.B. Deegan A Phase 3, multicenter, open-label, switchover trial to assess the safety and efficacy of taliglucerase alfa, a plant cell-expressed recombinant human glucocerebrosidase, in adult and pediatric patients with Gaucher disease previously treated with imiglucerase Blood Cells Mol Dis 53 2014 253 260
-
(2014)
Blood Cells Mol Dis
, vol.53
, pp. 253-260
-
-
Pastores, G.M.1
Petakov, M.2
Giraldo, P.3
Rosenbaum, H.4
Szer, J.5
Deegan, P.B.6
-
5
-
-
77954018796
-
Virus stalls Genzyme plant
-
V. Bethencourt Virus stalls Genzyme plant Nat Biotechnol 27 2009 681
-
(2009)
Nat Biotechnol
, vol.27
, pp. 681
-
-
Bethencourt, V.1
-
7
-
-
84856960863
-
Recovery and purification of plant-made recombinant proteins
-
L.R. Wilken, and Z.L. Nikolov Recovery and purification of plant-made recombinant proteins Biotechnol Adv 30 2012 419 433
-
(2012)
Biotechnol Adv
, vol.30
, pp. 419-433
-
-
Wilken, L.R.1
Nikolov, Z.L.2
-
8
-
-
84865375121
-
Predictive models for transient protein expression in tobacco (Nicotiana tabacum L.) can optimize process time, yield, and downstream costs
-
J.F. Buyel, and R. Fischer Predictive models for transient protein expression in tobacco (Nicotiana tabacum L.) can optimize process time, yield, and downstream costs Biotechnol Bioeng 109 2012 2575 2588
-
(2012)
Biotechnol Bioeng
, vol.109
, pp. 2575-2588
-
-
Buyel, J.F.1
Fischer, R.2
-
9
-
-
84888065349
-
Breakage of transgenic tobacco roots for monoclonal antibody release in an ultra-scale down shearing device
-
S. Hassan, E. Keshavarz-Moore, J. Ma, and C. Thomas Breakage of transgenic tobacco roots for monoclonal antibody release in an ultra-scale down shearing device Biotechnol Bioeng 111 2014 196 201
-
(2014)
Biotechnol Bioeng
, vol.111
, pp. 196-201
-
-
Hassan, S.1
Keshavarz-Moore, E.2
Ma, J.3
Thomas, C.4
-
10
-
-
84897584250
-
Scale-down models to optimize a filter train for the downstream purification of recombinant pharmaceutical proteins produced in tobacco leaves
-
J.F. Buyel, and R. Fischer Scale-down models to optimize a filter train for the downstream purification of recombinant pharmaceutical proteins produced in tobacco leaves Biotechnol J 9 2014 415 425
-
(2014)
Biotechnol J
, vol.9
, pp. 415-425
-
-
Buyel, J.F.1
Fischer, R.2
-
11
-
-
84901245118
-
Rational design of a host cell protein heat precipitation step simplifies the subsequent purification of recombinant proteins from tobacco
-
J.F. Buyel, H.M. Gruchow, A. Boes, and R. Fischer Rational design of a host cell protein heat precipitation step simplifies the subsequent purification of recombinant proteins from tobacco Biochem Eng J 88 2014 162 170
-
(2014)
Biochem Eng J
, vol.88
, pp. 162-170
-
-
Buyel, J.F.1
Gruchow, H.M.2
Boes, A.3
Fischer, R.4
-
12
-
-
84892885187
-
Flocculation increases the efficacy of depth filtration during the downstream processing of recombinant pharmaceutical proteins produced in tobacco
-
J.F. Buyel, and R. Fischer Flocculation increases the efficacy of depth filtration during the downstream processing of recombinant pharmaceutical proteins produced in tobacco Plant Biotechnol J 12 2014 240 252
-
(2014)
Plant Biotechnol J
, vol.12
, pp. 240-252
-
-
Buyel, J.F.1
Fischer, R.2
-
13
-
-
84901210391
-
Characterization of complex systems using the design of experiments approach: Transient protein expression in tobacco as a case study
-
J.F. Buyel, and R. Fischer Characterization of complex systems using the design of experiments approach: transient protein expression in tobacco as a case study J Vis Exp 1 2014 e51216
-
(2014)
J Vis Exp
, vol.1
, pp. e51216
-
-
Buyel, J.F.1
Fischer, R.2
-
14
-
-
39849091107
-
Spectrophotometric and colorimetric determination of protein concentration
-
M.H. Simonian, and J.A. Smith Spectrophotometric and colorimetric determination of protein concentration Curr Protoc Mol Biol 2006 http://dx.doi.org/10.1002/0471142727.mb1001as76
-
(2006)
Curr Protoc Mol Biol
-
-
Simonian, M.H.1
Smith, J.A.2
-
15
-
-
84877717309
-
Processing heterogeneous biomass: Overcoming the hurdles in model building
-
J.F. Buyel, and R. Fischer Processing heterogeneous biomass: overcoming the hurdles in model building Bioengineered 4 2013 21 24
-
(2013)
Bioengineered
, vol.4
, pp. 21-24
-
-
Buyel, J.F.1
Fischer, R.2
-
16
-
-
77649269732
-
Purification performance index and separation cost indicator for experimentally based systematic downstream process development
-
T. Winkelnkemper, and G. Schembecker Purification performance index and separation cost indicator for experimentally based systematic downstream process development Sep Purif Technol 72 2010 34 39
-
(2010)
Sep Purif Technol
, vol.72
, pp. 34-39
-
-
Winkelnkemper, T.1
Schembecker, G.2
-
17
-
-
84055223600
-
Comparative evaluation of extraction methods for apoplastic proteins from maize leaves
-
K. Witzel, M. Shahzad, A. Matros, H.P. Mock, and K.H. Muhling Comparative evaluation of extraction methods for apoplastic proteins from maize leaves Plant Methods 2011 7
-
(2011)
Plant Methods
, pp. 7
-
-
Witzel, K.1
Shahzad, M.2
Matros, A.3
Mock, H.P.4
Muhling, K.H.5
-
18
-
-
84887553366
-
End-to-end continuous manufacturing of pharmaceuticals: Integrated synthesis, purification, and final dosage formation
-
S. Mascia, P.L. Heider, H.T. Zhang, R. Lakerveld, B. Benyahia, and P.I. Barton End-to-end continuous manufacturing of pharmaceuticals: integrated synthesis, purification, and final dosage formation Angew Chem Int Ed 52 2013 12359 12363
-
(2013)
Angew Chem Int Ed
, vol.52
, pp. 12359-12363
-
-
Mascia, S.1
Heider, P.L.2
Zhang, H.T.3
Lakerveld, R.4
Benyahia, B.5
Barton, P.I.6
-
19
-
-
35948998871
-
Continuous processes for the production of pharmaceutical intermediates and active pharmaceutical ingredients
-
T.L. LaPorte, and C. Wang Continuous processes for the production of pharmaceutical intermediates and active pharmaceutical ingredients Curr Opin Drug Disc 10 2007 738 745
-
(2007)
Curr Opin Drug Disc
, vol.10
, pp. 738-745
-
-
Laporte, T.L.1
Wang, C.2
-
20
-
-
37749018864
-
Continuous counter current extraction, isolation and determination of solanesol in Nicotiana tobacum L. by non-aqueous reversed phase high performance liquid chromatography
-
R.N. Rao, M.V.N.K. Talluri, T.S.V.N.M. Krishna, and K. Ravindranath Continuous counter current extraction, isolation and determination of solanesol in Nicotiana tobacum L. by non-aqueous reversed phase high performance liquid chromatography J Pharm Biomed Anal 46 2008 310 315
-
(2008)
J Pharm Biomed Anal
, vol.46
, pp. 310-315
-
-
Rao, R.N.1
Talluri, M.V.N.K.2
Krishna, T.S.V.N.M.3
Ravindranath, K.4
-
21
-
-
4544255101
-
Development of multi-stage countercurrent extraction technology for the extraction of glycyrrhizic acid (GA) from licorice (Glycyrrhiza uralensis Fisch)
-
Q.E. Wang, S.M. Ma, B.Q. Fu, F.S.C. Lee, and X.R. Wang Development of multi-stage countercurrent extraction technology for the extraction of glycyrrhizic acid (GA) from licorice (Glycyrrhiza uralensis Fisch) Biochem Eng J 21 2004 285 292
-
(2004)
Biochem Eng J
, vol.21
, pp. 285-292
-
-
Wang, Q.E.1
Ma, S.M.2
Fu, B.Q.3
Lee, F.S.C.4
Wang, X.R.5
-
22
-
-
45149131892
-
Advances in primary recovery: Centrifugation and membrane technology
-
D.J. Roush, and Y.F. Lu Advances in primary recovery: centrifugation and membrane technology Biotechnol Prog 24 2008 488 495
-
(2008)
Biotechnol Prog
, vol.24
, pp. 488-495
-
-
Roush, D.J.1
Lu, Y.F.2
-
23
-
-
77958589701
-
Recovery and purification process development for monoclonal antibody production
-
H.F. Liu, J. Ma, C. Winter, and R. Bayer Recovery and purification process development for monoclonal antibody production mAbs 2 2010 480 499
-
(2010)
MAbs
, vol.2
, pp. 480-499
-
-
Liu, H.F.1
Ma, J.2
Winter, C.3
Bayer, R.4
-
24
-
-
76849095703
-
Purification of the two major proteins from whey concentrate using a cation-exchange selective adsorption process
-
M.M.H. El-Sayed, and H.A. Chase Purification of the two major proteins from whey concentrate using a cation-exchange selective adsorption process Biotechnol Prog 26 2010 192 199
-
(2010)
Biotechnol Prog
, vol.26
, pp. 192-199
-
-
El-Sayed, M.M.H.1
Chase, H.A.2
-
25
-
-
0012370528
-
Case study process development of chromatography steps for purification of a recombinant E. Coli expressed protein
-
A. Rathore, A. Velayudhan, Marcel Dekker Inc. New York, NY
-
A. Rathore Case study process development of chromatography steps for purification of a recombinant E. coli expressed protein A. Rathore, A. Velayudhan, Scale-up and optimization in preparative chromatography: principles and biopharmaceutical applications vol. 88 2002 Marcel Dekker Inc. New York, NY 22
-
(2002)
Scale-up and Optimization in Preparative Chromatography: Principles and Biopharmaceutical Applications
, vol.88
, pp. 22
-
-
Rathore, A.1
-
26
-
-
80054684723
-
Adsorption and flocculation by polymers and polymer mixtures
-
J. Gregory, and S. Barany Adsorption and flocculation by polymers and polymer mixtures Adv Colloid Interface Sci 169 2011 1 12
-
(2011)
Adv Colloid Interface Sci
, vol.169
, pp. 1-12
-
-
Gregory, J.1
Barany, S.2
-
27
-
-
0242475327
-
Molecular farming in plants: Host systems and expression technology
-
R.M. Twyman, E. Stoger, S. Schillberg, P. Christou, and R. Fischer Molecular farming in plants: host systems and expression technology Trends Biotechnol 21 2003 570 578
-
(2003)
Trends Biotechnol
, vol.21
, pp. 570-578
-
-
Twyman, R.M.1
Stoger, E.2
Schillberg, S.3
Christou, P.4
Fischer, R.5
-
28
-
-
0005201291
-
Separations in biotechnology
-
R.M. Ladisch, R.C. Willson, C.C. Painton, S.E. Builder, American Chemical Society Washington, D.C.
-
E.N. Lightfoot Separations in biotechnology R.M. Ladisch, R.C. Willson, C.C. Painton, S.E. Builder, Protein purification - from molecular mechanisms to large-scale processes vol. 427 1990 American Chemical Society Washington, D.C. 35 51
-
(1990)
Protein Purification - From Molecular Mechanisms to Large-scale Processes
, vol.427
, pp. 35-51
-
-
Lightfoot, E.N.1
-
31
-
-
84881347629
-
Optimizing the yield of recombinant pharmaceutical proteins in plants
-
R.M. Twyman, S. Schillberg, and R. Fischer Optimizing the yield of recombinant pharmaceutical proteins in plants Curr Pharm Des 19 2013 5486 5494
-
(2013)
Curr Pharm des
, vol.19
, pp. 5486-5494
-
-
Twyman, R.M.1
Schillberg, S.2
Fischer, R.3
|