Inflammatory Stress Exacerbated Mesangial Foam Cell Formation and Renal Injury via Disrupting Cellular Cholesterol Homeostasis

Inflammation

Volumn 38, Issue 3, 2015, Pages 959-971

  Zhong, Shan ^a   Zhao, Lei ^a   Li, Qing ^a   Yang, Ping ^a   Varghese, Zac ^b   Moorhead, John F ^b   Chen, Yaxi ^a   Ruan, Xiong Z ^a,b  

^a CHONGQING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

ABCA1; cholesterol; ER stress; HMGCoA reductase; inflammation; LDL receptor; LXR ; oxidative stress

Indexed keywords

MUS;

ABC TRANSPORTER A1; ACTIVATING TRANSCRIPTION FACTOR 6; ATF6 PROTEIN, MOUSE; CASEIN; CHOLESTEROL; CREATININE; ERN1 PROTEIN, MOUSE; HYDROGEN PEROXIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; IL1B PROTEIN, MOUSE; INTERLEUKIN 1BETA; LIVER X RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR; ORPHAN NUCLEAR RECEPTOR; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE; SERUM AMYLOID A; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; BIOSYNTHESIS; BLOOD; C57BL MOUSE; CELL LINE; CHRONIC KIDNEY FAILURE; ENDOPLASMIC RETICULUM STRESS; FOAM CELL; HUMAN; INFLAMMATION; KIDNEY; LIPID METABOLISM; MALE; MESANGIUM CELL; METABOLISM; MOUSE; PATHOLOGY; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ACTIVATING TRANSCRIPTION FACTOR 6; ANIMALS; ATP BINDING CASSETTE TRANSPORTER 1; BIOLOGICAL TRANSPORT; CASEINS; CELL LINE; CHOLESTEROL; CREATININE; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; FOAM CELLS; HUMANS; HYDROGEN PEROXIDE; HYDROXYMETHYLGLUTARYL COA REDUCTASES; INFLAMMATION; INTERLEUKIN-1BETA; KIDNEY; LIPID METABOLISM; MALE; MESANGIAL CELLS; MICE; MICE, INBRED C57BL; ORPHAN NUCLEAR RECEPTORS; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, LDL; RENAL INSUFFICIENCY, CHRONIC; SERUM AMYLOID A PROTEIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84939940819     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-0058-0     Document Type: Article

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