miR-146a and miR-196a2 Polymorphisms in Patients with Ischemic Stroke in the Northern Chinese Han Population

Neurochemical Research

Volumn 39, Issue 9, 2014, Pages 1709-1716

  Zhu, Ruixia ^a   Liu, Xu ^a   He, Zhiyi ^a   Li, Qu ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Ischemic stroke; miR 146a; miR 196a2; Polymorphisms

Indexed keywords

MICRORNA; MIRN146 MICRORNA, HUMAN; MIRN196 MICRORNA, HUMAN;

ADULT; AGED; CASE CONTROL STUDY; CEREBROVASCULAR ACCIDENT; CHINA; ETHNIC GROUP; FEMALE; GENE FREQUENCY; GENETICS; HUMAN; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; CHINA; ETHNIC GROUPS; FEMALE; GENE FREQUENCY; HUMANS; MALE; MICRORNAS; MIDDLE AGED; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; STROKE;

EID: 84939895773     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-014-1364-5     Document Type: Article

References (35)

1. Liu L, Wang D, Wong KS, Wang Y (2011) Stroke and stroke care in China: huge burden, significant workload, and a national priority. Stroke 42:3651–3654
2. Liu M, Wu B, Wang WZ, Lee LM, Zhang SH, Kong LZ (2007) Stroke in China: epidemiology, prevention, and management strategies. Lancet Neurol 6:456–464
3. Jia Q, Liu LP, Wang YJ (2010) Stroke in China. Clin Exp Pharmacol Physiol 37:259–264
4. Domingues-Montanari S, Mendioroz M, del Rio-Espinola A, Fernández-Cadenas I, Montaner J (2008) Genetics of stroke: a review of recent advances. Expert Rev Mol Diagn 8:495–513
5. Pluta R, Kocki J, Maciejewski R, Ułamek-Kozioł M, Jabłoński M, Bogucka-Kocka A, Czuczwar SJ (2012) Ischemia signalling to Alzheimer-related genes. Folia Neuropathol 50(4):322–329
6. Pluta R, Jabłoński M, Ułamek-Kozioł M, Kocki J, Brzozowska J, Januszewski S, Furmaga-Jabłońska W, Bogucka-Kocka A, Maciejewski R, Czuczwar SJ (2013) Sporadic Alzheimer’s disease begins as episodes of brain ischemia and ischemically dysregulated Alzheimer’s disease genes. Mol Neurobiol 48(3):500–515
7. Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281–297
8. Filipowicz W, Bhattacharyya SN, Sonenberg N (2008) Mechanisms of posttranscriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9:102–114
9. Ambros V (2004) The functions of animal microRNAs. Nature 431:350–355
10. Rink C, Khanna S (2011) MicroRNA in ischemic stroke etiology and pathology. Physiol Genomics 43:521–528
11. Tan JR, Koo YX, Kaur P, Liu F, Armugam A, Wong PT, Jeyaseelan K (2011) microRNAs in stroke pathogenesis. Curr Mol Med 11:76–92
12. Vickers KC, Remaley AT (2010) MicroRNAs in atherosclerosis and lipoprotein metabolism. Curr Opin Endocrinol Diabetes Obes 17(2):150–155
13. Jeyaseelan K, Lim KY, Armugam A (2008) MicroRNA expression in the blood and brain of rats subjected to transient focal ischemia by middle cerebral artery occlusion. Stroke 39:959–966
14. Tan KS, Armugam A, Sepramaniam S et al (2009) Expression profile of microRNAs in young stroke patients. PLoS ONE 4(11):e7689
15. Shastry BS (2009) SNPs: impact on gene function and phenotype. Methods Mol Biol 578:3–22
16. Duan RH, Pak CH, Jin P (2007) Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA. Hum Mol Genet 16(9):1124–1131
17. Ryan BM, Robles AI, Harris CC (2010) Genetic variation in microRNA networks: the implications for cancer research. Nat Rev Cancer 10(6):389–402
18. Saunders MA, Liang H, Li WH (2007) Human polymorphism at microRNAs and microRNA target sites. Proc Natl Acad Sci USA 27(104):3300–3305
19. Gong J, Tong Y, Zhang HM, Wang K, Hu T, Shan G, Sun J, Guo AY (2012) Genome-wide identification of SNPs in MicroRNA genes and the SNP effects on MicroRNA target binding and biogenesis. Hum Mutat 33:254–263
20. Guarnieri DJ, DiLeone RJ (2008) MicroRNAs: a new class of gene regulators. Ann Med 40:197–208
21. Jazdzewski K, Murray EL, Franssila K, Jarzab B, Schoenberg DR, de la Chappell A (2008) Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. Proc Natl Acad Sci USA 105:7269–7274
22. Hu Z, Chen J, Tian T, Zhou X, Gu H, Xu L, Zeng Y, Miao R, Jin G, Ma H, Chen Y, Shen H (2008) Genetic variants of miRNA sequences and non-small cell lung cancer survival. J Clin Investig 118:2600–2608
23. Zhi H, Wang L, Ma G, Ye X, Yu X, Zhu Y, Zhang Y, Zhang J, Wang B (2012) Polymorphisms of miRNAs genes are associated with the risk and prognosis of coronary artery disease. Clin Res Cardiol 101:289–296
24. Taganov KD, Boldin MP, Chang KJ, Baltimore D (2006) NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 103(33):12481–12486
25. Luthra R, Singh RR, Luthra MG, Li YX, Hannah C, Romans AM, Barkoh BA, Chen SS, Ensor J, Maru DM, Broaddus RR, Rashid A, Albarracin CT (2008) MicroRNA-196a targets annexin A1: a microRNA-mediated mechanism of annexin A1downregulation in cancers. Oncogene 27(52):6667–6678
26. Ringwood L, Li L (2008) The involvement of the interleukin-1 receptor-associated kinases (IRAKs) in cellular signaling networks controlling inflammation. Cytokine 42(1):1–7
27. Chung JY, Park YC, Ye H, Wu H (2002) All TRAFs are not created equal: common and distinct molecular mechanisms of TRAF-mediated signal transduction. J Cell Sci 115(Pt4):679–688
28. Chen T, Li Z, Jing T, Zhu W, Ge J, Zheng X, Pan X, Yan H, Zhu J (2011) MicroRNA-146a regulates the maturation process and Pro-inflammatory cytokine secretion by targeting CD40L in oxLDL-stimulated dendritic cells. FEBS Lett 585(3):567–573
29. Jeon YJ, Kim OJ, Kim SY, Oh SH, Oh D, Kim OJ, Shin BS, Kim NK (2012) Association of the miR-146a, miR-149, miR-196a2, and miR-499 polymorphisms with ischemic stroke and silent brain infarction risk. Arterioscler Thromb Vasc Biol 33:420–430
30. Shen J, Ambrosone CB, DiCioccio RA, Odunsi K, Lele SB, Zhao H (2008) A functional polymorphism in the miR-146a gene and age of familial breast/ovarian cancer diagnosis. Carcinogenesis 29:1963–1966
31. Zeng Y, Cullen BR (2003) Sequence requirements for microRNA processing and function in human cells. RNA 9:112
32. Parente L, Solito E (2004) Annexin 1: more than an anti-phospholipase protein. Inflamm Res 53:125–132
33. Perretti M, D’Acquisto F (2009) Annexin A1 and glucocorticoids as effectors of the resolution of inflammation. Nat Rev Immunol 9:62–70
34. La M, D’Amico M, Bandiera S, Di Filippo C, Oliani SM, Gavins FN, Flower RJ, Perretti M (2001) Annexin 1 peptides protect against experimental myocardial ischemia-reperfusion: analysis of their mechanism of action. FASEB J 15:2247–2256
35. Park YS, Jeon YJ, Lee BE, Kim TG, Choi JU, Kim DS, Kim NK (2012) Association of the miR-146aC>G, miR-196a2C>T, and miR-499A>G polymorphisms with moyamoya disease in the Korean population. Neurosci Lett 521:71–75