The effect of polymeric excipients on the physical properties and performance of amorphous dispersions: Part I, free volume and glass transition

Pharmaceutical Research

Volumn 32, Issue 2, 2015, Pages 500-515

  Li, Jinjiang ^a   Zhao, Junshu ^a   Tao, Li ^a   Wang, Jennifer ^a,b   Waknis, Vrushali ^a   Pan, Duohai ^a   Hubert, Mario ^a   Raghavan, Krishnaswamy ^a   Patel, Jatin ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b TEVA PHARMACEUTICALS   (Israel)

Author keywords

Amorphous dispersions; Chain rigidity and solution comformation; Free volume by PALS; Glass transition; Polymeric excipients: Cellulose derivatives and ployvinyl polymers

Indexed keywords

EXCIPIENT; GLASS; INDOMETACIN; KETOCONAZOLE; POLYMER;

CHEMISTRY; TRANSITION TEMPERATURE;

EXCIPIENTS; GLASS; INDOMETHACIN; KETOCONAZOLE; POLYMERS; TRANSITION TEMPERATURE;

EID: 84939886951     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-014-1478-0     Document Type: Article

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