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Volumn 55, Issue 1, 2015, Pages 233-239

The Role of LRRK2 in the Regulation of Monocyte Adhesion to Endothelial Cells

Author keywords

Leucine rich repeat kinase 2 (LRRK2); Monocyte adhesion; Nuclear factor B (NF B); Vascular inflammation; VCAM 1

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LRRK2 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; VASCULAR CELL ADHESION MOLECULE 1;

EID: 84939885719     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0312-9     Document Type: Article
Times cited : (21)

References (24)
  • 1
    • 0345118282 scopus 로고    scopus 로고
    • Roc, a Ras/GTPase domain in complex proteins
    • COI: 1:CAS:528:DC%2BD3sXptlOqtLg%3D, PID: 14654223
    • Bosgraaf L, Van Haastert PJ (2003) Roc, a Ras/GTPase domain in complex proteins. Biochim Biophys Acta 1643:5–10
    • (2003) Biochim Biophys Acta , vol.1643 , pp. 5-10
    • Bosgraaf, L.1    Van Haastert, P.J.2
  • 2
    • 77952122496 scopus 로고    scopus 로고
    • LRRK2 and Parkinson disease
    • PID: 20457952
    • Dächsel JC, Farrer MJ (2010) LRRK2 and Parkinson disease. Arch Neurol 67:542–547
    • (2010) Arch Neurol , vol.67 , pp. 542-547
    • Dächsel, J.C.1    Farrer, M.J.2
  • 3
    • 0033944494 scopus 로고    scopus 로고
    • Pathological features of cerebral cortical capillaries are doubled in Alzheimer’s disease and Parkinson’s disease
    • COI: 1:CAS:528:DC%2BD3cXltVyrurw%3D, PID: 10985698
    • Farkas E, De Jong GI, de Vos RA, Jansen Steur EN, Luiten PG (2000) Pathological features of cerebral cortical capillaries are doubled in Alzheimer’s disease and Parkinson’s disease. Acta Neuropathol 100:395–402
    • (2000) Acta Neuropathol , vol.100 , pp. 395-402
    • Farkas, E.1    De Jong, G.I.2    de Vos, R.A.3    Jansen Steur, E.N.4    Luiten, P.G.5
  • 5
    • 0034085698 scopus 로고    scopus 로고
    • Endothelial dysfunction, hemodynamic forces, and atherogenesis
    • COI: 1:CAS:528:DC%2BD3cXksFSksrs%3D, PID: 10865843, discussion 239–240
    • Gimbrone MA Jr, Topper JN, Nagel T, Anderson KR, Garcia-Cardena G (2000) Endothelial dysfunction, hemodynamic forces, and atherogenesis. Ann N Y Acad Sci 902:230–239, discussion 239–240
    • (2000) Ann N Y Acad Sci , vol.902 , pp. 230-239
    • Gimbrone, M.A.1    Topper, J.N.2    Nagel, T.3    Anderson, K.R.4    Garcia-Cardena, G.5
  • 6
    • 77953395313 scopus 로고    scopus 로고
    • Leucine-rich repeat kinase 2 mutations and Parkinson’s disease: three questions
    • Greggio E, Cookson MR (2009) Leucine-rich repeat kinase 2 mutations and Parkinson’s disease: three questions. ASN Neurol 1:e00002
    • (2009) ASN Neurol , vol.1 , pp. e00002
    • Greggio, E.1    Cookson, M.R.2
  • 7
    • 34548604567 scopus 로고    scopus 로고
    • The Parkinson’s disease associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity
    • COI: 1:CAS:528:DC%2BD2sXhtVOlsbfM, PID: 17706965
    • Guo L, Gandhi PN, Wang W, Petersen RB, Wilson-Delfosse AL, Chen SG (2007) The Parkinson’s disease associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity. Exp Cell Res 313:3658–3670
    • (2007) Exp Cell Res , vol.313 , pp. 3658-3670
    • Guo, L.1    Gandhi, P.N.2    Wang, W.3    Petersen, R.B.4    Wilson-Delfosse, A.L.5    Chen, S.G.6
  • 9
    • 50049104725 scopus 로고    scopus 로고
    • Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson’s disease: a case–control study
    • COI: 1:CAS:528:DC%2BD1cXptVWju7o%3D, PID: 18539534
    • Healy DG et al (2008) Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson’s disease: a case–control study. Lancet Neurol 7:583–590
    • (2008) Lancet Neurol , vol.7 , pp. 583-590
    • Healy, D.G.1
  • 10
    • 13144255682 scopus 로고    scopus 로고
    • Blood-brain barrier dysfunction in parkinsonian midbrain in vivo
    • COI: 1:CAS:528:DC%2BD2MXhs1Cisbw%3D, PID: 15668963
    • Kortekaas R, Lenders KL, van Oostrom JCH et al (2005) Blood-brain barrier dysfunction in parkinsonian midbrain in vivo. Ann Neurol 57:176–179
    • (2005) Ann Neurol , vol.57 , pp. 176-179
    • Kortekaas, R.1    Lenders, K.L.2    van Oostrom, J.C.H.3
  • 11
    • 79960361814 scopus 로고    scopus 로고
    • Recent advances in the genetics of Parkinson’s disease
    • COI: 1:CAS:528:DC%2BC3MXht1yksbvN, PID: 21639795
    • Martin I et al (2011) Recent advances in the genetics of Parkinson’s disease. Annu Rev Genomics Hum Genet 12:301–325
    • (2011) Annu Rev Genomics Hum Genet , vol.12 , pp. 301-325
    • Martin, I.1
  • 13
    • 0030582991 scopus 로고    scopus 로고
    • Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile Parkinsonism and Parkinson’s disease
    • COI: 1:CAS:528:DyaK28Xkt1Sqt74%3D
    • Mogi M, Harada M, Narabayashi H, Inagaki H, Minami M, Nagatsu T (1996) Interleukin (IL)-1 beta, IL-2, IL-4, IL-6 and transforming growth factor-alpha levels are elevated in ventricular cerebrospinal fluid in juvenile Parkinsonism and Parkinson’s disease. Neuroscience 211:13–16
    • (1996) Neuroscience , vol.211 , pp. 13-16
    • Mogi, M.1    Harada, M.2    Narabayashi, H.3    Inagaki, H.4    Minami, M.5    Nagatsu, T.6
  • 14
    • 33846920571 scopus 로고    scopus 로고
    • p53 protein, interferon-c, and NF-kB levels are elevated in the parkinsonian brain
    • COI: 1:CAS:528:DC%2BD2sXhvVyks78%3D, PID: 17196747
    • Mogi M, Kondo T, Mizuno Y, Nagatsu T (2007) p53 protein, interferon-c, and NF-kB levels are elevated in the parkinsonian brain. Neurosci Lett 414:94–97
    • (2007) Neurosci Lett , vol.414 , pp. 94-97
    • Mogi, M.1    Kondo, T.2    Mizuno, Y.3    Nagatsu, T.4
  • 15
    • 14744296610 scopus 로고    scopus 로고
    • Inflammatory process in Parkinson’s disease: role for cytokines
    • COI: 1:CAS:528:DC%2BD2MXhvVChurk%3D, PID: 15777250
    • Nagatsu T, Sawada M (2005) Inflammatory process in Parkinson’s disease: role for cytokines. Curr Pharm Des 11:999–1016
    • (2005) Curr Pharm Des , vol.11 , pp. 999-1016
    • Nagatsu, T.1    Sawada, M.2
  • 16
    • 84855687153 scopus 로고    scopus 로고
    • Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BC38XitVKksbk%3D, PID: 22077634
    • Sheng B, Wang X, Su B, Lee HG, Casadesus G et al (2012) Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease. J Neurochem 120(3):419–429
    • (2012) J Neurochem , vol.120 , Issue.3 , pp. 419-429
    • Sheng, B.1    Wang, X.2    Su, B.3    Lee, H.G.4    Casadesus, G.5
  • 17
    • 84878613638 scopus 로고    scopus 로고
    • Kruppel-like factor 2 protects against ischemic stroke by regulating endothelial blood brain barrier function
    • COI: 1:CAS:528:DC%2BC3sXlvVKgs7o%3D, PID: 23335794
    • Shi H, Sheng B, Zhang F (2013) Kruppel-like factor 2 protects against ischemic stroke by regulating endothelial blood brain barrier function. Am J Physiol Heart Circ Physiol 304(6):H796–H805
    • (2013) Am J Physiol Heart Circ Physiol , vol.304 , Issue.6 , pp. H796-H805
    • Shi, H.1    Sheng, B.2    Zhang, F.3
  • 18
    • 33748993710 scopus 로고    scopus 로고
    • Kinase activity of mutant LRRK2 mediates neuronal toxicity
    • COI: 1:CAS:528:DC%2BD28XhtVSgu7fJ, PID: 16980962
    • Smith WW, Pei Z, Jiang H, Dawson VL, Dawson TM, Ross CA (2006) Kinase activity of mutant LRRK2 mediates neuronal toxicity. Nat Neurosci 9:1231–1233
    • (2006) Nat Neurosci , vol.9 , pp. 1231-1233
    • Smith, W.W.1    Pei, Z.2    Jiang, H.3    Dawson, V.L.4    Dawson, T.M.5    Ross, C.A.6
  • 19
    • 0027982876 scopus 로고
    • Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm
    • COI: 1:CAS:528:DyaK2cXhs1Srtrg%3D, PID: 7507411
    • Springer TA (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76:301–314
    • (1994) Cell , vol.76 , pp. 301-314
    • Springer, T.A.1
  • 20
    • 79959575659 scopus 로고    scopus 로고
    • Regulation of LRRK2 expression points to a functional role in human monocyte maturation
    • COI: 1:CAS:528:DC%2BC3MXosVajtbw%3D, PID: 21738687
    • Thevenet J, Pescini Gobert R, Hooft van Huijsduijnen R, Wiessner C, Sagot YJ (2011) Regulation of LRRK2 expression points to a functional role in human monocyte maturation. PLoS One 6:e21519
    • (2011) PLoS One , vol.6 , pp. e21519
    • Thevenet, J.1    Pescini Gobert, R.2    Hooft van Huijsduijnen, R.3    Wiessner, C.4    Sagot, Y.J.5
  • 21
  • 22
    • 84870542457 scopus 로고    scopus 로고
    • Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice
    • COI: 1:CAS:528:DC%2BC38XhvVaktL7P, PID: 23160196
    • Zhou G, Hamik A, Nayak L et al (2012) Endothelial Kruppel-like factor 4 protects against atherothrombosis in mice. J Clin Invest 122(12):4727–4731
    • (2012) J Clin Invest , vol.122 , Issue.12 , pp. 4727-4731
    • Zhou, G.1    Hamik, A.2    Nayak, L.3
  • 24
    • 8844233579 scopus 로고    scopus 로고
    • Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
    • COI: 1:CAS:528:DC%2BD2cXhtVKhurjL, PID: 15541309
    • Zimprich A et al (2004b) Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 44:601–607
    • (2004) Neuron , vol.44 , pp. 601-607
    • Zimprich, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.