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Volumn 230, Issue 12, 2015, Pages 2973-2980

Anti Proliferative and Pro Apoptotic Effects of Flavonoid Quercetin Are Mediated by CB1 Receptor in Human Colon Cancer Cell Lines

Author keywords

[No Author keywords available]

Indexed keywords

ANANDAMIDE; BETA CATENIN; CANNABINOID 1 RECEPTOR; GLYCOGEN SYNTHASE KINASE 3BETA; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; QUERCETIN; RIMONABANT; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; ANTINEOPLASTIC AGENT; CANNABINOID RECEPTOR AGONIST; CNR1 PROTEIN, HUMAN;

EID: 84939863506     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.25026     Document Type: Article
Times cited : (94)

References (39)
  • 7
    • 33751082422 scopus 로고    scopus 로고
    • Quercetin induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI-3-kinase/Akt and ERK pathways in a human hepatoma cell line (HepG2)
    • Granado-Serrano AB, Martín MA, Bravo L, Goya L, Ramos S. 2006. Quercetin induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI-3-kinase/Akt and ERK pathways in a human hepatoma cell line (HepG2). J Nutr 136:2715-2721.
    • (2006) J Nutr , vol.136 , pp. 2715-2721
    • Granado-Serrano, A.B.1    Martín, M.A.2    Bravo, L.3    Goya, L.4    Ramos, S.5
  • 8
    • 35348910284 scopus 로고    scopus 로고
    • The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells
    • Greenhough A, Patsos HA, Williams AC, Paraskeva C. 2007. The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells. Int J Cancer 121:2172-2180.
    • (2007) Int J Cancer , vol.121 , pp. 2172-2180
    • Greenhough, A.1    Patsos, H.A.2    Williams, A.C.3    Paraskeva, C.4
  • 11
    • 3242724820 scopus 로고    scopus 로고
    • Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes
    • Joseph J, Niggemann B, Zaenker KS, Entschladen F. 2004. Anandamide is an endogenous inhibitor for the migration of tumor cells and T lymphocytes. Cancer Immunol Immunother 53:723-728.
    • (2004) Cancer Immunol Immunother , vol.53 , pp. 723-728
    • Joseph, J.1    Niggemann, B.2    Zaenker, K.S.3    Entschladen, F.4
  • 13
    • 0030596107 scopus 로고    scopus 로고
    • Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells
    • Kuo SM. 1996. Antiproliferative potency of structurally distinct dietary flavonoids on human colon cancer cells. Cancer Lett 110:41-48.
    • (1996) Cancer Lett , vol.110 , pp. 41-48
    • Kuo, S.M.1
  • 15
    • 34347218991 scopus 로고    scopus 로고
    • In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro
    • Liang CC, Park AY, Guan JL. 2007. In vitro scratch assay: A convenient and inexpensive method for analysis of cell migration in vitro. Nat Protoc 2:329-333.
    • (2007) Nat Protoc , vol.2 , pp. 329-333
    • Liang, C.C.1    Park, A.Y.2    Guan, J.L.3
  • 19
    • 51349127271 scopus 로고    scopus 로고
    • Multitargeted cancer prevention by quercetin
    • Murakami A, Ashida H, Terao J. 2008. Multitargeted cancer prevention by quercetin. Cancer Lett 269:315-325.
    • (2008) Cancer Lett , vol.269 , pp. 315-325
    • Murakami, A.1    Ashida, H.2    Terao, J.3
  • 21
    • 2442623486 scopus 로고    scopus 로고
    • The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells
    • Nuyen TT, Tran E, Nguyen TH, Do PT, Huynh TH, Huynh H. 2004. The role of activated MEK-ERK pathway in quercetin-induced growth inhibition and apoptosis in A549 lung cancer cells. Carcinogenesis 25:647-659.
    • (2004) Carcinogenesis , vol.25 , pp. 647-659
    • Nuyen, T.T.1    Tran, E.2    Nguyen, T.H.3    Do, P.T.4    Huynh, T.H.5    Huynh, H.6
  • 22
    • 33748703859 scopus 로고    scopus 로고
    • The endocannabinoid system as an emerging target of pharmacotherapy
    • Pacher P, Bátkai S, Kunos G. 2006. The endocannabinoid system as an emerging target of pharmacotherapy. Pharmacol Rev 58:389-462.
    • (2006) Pharmacol Rev , vol.58 , pp. 389-462
    • Pacher, P.1    Bátkai, S.2    Kunos, G.3
  • 23
  • 25
    • 0030611978 scopus 로고    scopus 로고
    • Pharmacology of cannabinoid CB1 and CB2 receptors
    • Pertwee RG. 1997. Pharmacology of cannabinoid CB1 and CB2 receptors. Pharmacol Ther 74:129-180.
    • (1997) Pharmacol Ther , vol.74 , pp. 129-180
    • Pertwee, R.G.1
  • 26
    • 65449146377 scopus 로고    scopus 로고
    • Emerging strategies for exploiting cannabinoid receptor agonists as medicines
    • Pertwee RG. 2009. Emerging strategies for exploiting cannabinoid receptor agonists as medicines. Br J Pharmacol 156:397-411.
    • (2009) Br J Pharmacol , vol.156 , pp. 397-411
    • Pertwee, R.G.1
  • 27
    • 0036739344 scopus 로고    scopus 로고
    • Oestrogen-induced apoptosis in colonocytes expressing oestrogen receptor β
    • Qiu Y, Waters CE, Lewis AE, Langman MJS, Eggo MC. 2002. Oestrogen-induced apoptosis in colonocytes expressing oestrogen receptor β. J Endocrinol 174:369-377.
    • (2002) J Endocrinol , vol.174 , pp. 369-377
    • Qiu, Y.1    Waters, C.E.2    Lewis, A.E.3    Langman, M.J.S.4    Eggo, M.C.5
  • 28
    • 0036400016 scopus 로고    scopus 로고
    • Dietary flavonoids: Bioavailability, metabolic effects, and safety
    • Ross JA, Kasum CM. 2002. Dietary flavonoids: Bioavailability, metabolic effects, and safety. Annu Rev Nutr 22:19-34.
    • (2002) Annu Rev Nutr , vol.22 , pp. 19-34
    • Ross, J.A.1    Kasum, C.M.2
  • 31
    • 84900796850 scopus 로고    scopus 로고
    • The potential of targeting Wnt/β-catenin in colon cancer
    • Sebio A, Kahn M, Lenz HJ. 2014. The potential of targeting Wnt/β-catenin in colon cancer. Expert Opin Ther Targets 18:611-615.
    • (2014) Expert Opin Ther Targets , vol.18 , pp. 611-615
    • Sebio, A.1    Kahn, M.2    Lenz, H.J.3
  • 32
    • 0033969544 scopus 로고    scopus 로고
    • Differential effects of flavonoid compounds on tumor promoter-induced activation of the human CYP1A2 enhancer
    • Shih H, Pickwell GV, Quattrochi LC. 2000. Differential effects of flavonoid compounds on tumor promoter-induced activation of the human CYP1A2 enhancer. Arch Biochem Biophys 373:287-294.
    • (2000) Arch Biochem Biophys , vol.373 , pp. 287-294
    • Shih, H.1    Pickwell, G.V.2    Quattrochi, L.C.3
  • 33
    • 84883485892 scopus 로고    scopus 로고
    • Potential Targets for Colorectal Cancer Prevention
    • Temraz S, Mukherji D, Shamseddine A. 2013. Potential Targets for Colorectal Cancer Prevention. Int J Mol Sci 14:17279-17303.
    • (2013) Int J Mol Sci , vol.14 , pp. 17279-17303
    • Temraz, S.1    Mukherji, D.2    Shamseddine, A.3
  • 34
    • 17844361910 scopus 로고    scopus 로고
    • Integrated assessment by multiple gene expression analysis of quercetin bioactivity on anticancer-related mechanisms in colon cancer cells in vitro
    • van Erk MJ, Roepman P, van der Lende TR, Stierum RH, Aarts JM, van Bladeren PJ, van Ommen B. 2005. Integrated assessment by multiple gene expression analysis of quercetin bioactivity on anticancer-related mechanisms in colon cancer cells in vitro. Eur J Nutr 44:143-156.
    • (2005) Eur J Nutr , vol.44 , pp. 143-156
    • van Erk, M.J.1    Roepman, P.2    van der Lende, T.R.3    Stierum, R.H.4    Aarts, J.M.5    van Bladeren, P.J.6    van Ommen, B.7
  • 37
    • 33750298256 scopus 로고    scopus 로고
    • Overexpression of cannabinoid receptors CB1 and CB2 correlates with improved prognosis of patients with hepatocellular carcinoma
    • Xu X, Liu Y, Huang S, Liu G, Xie C, Zhou J, Fan W, Li Q, Wang Q, Zhong D, Miao X. 2006. Overexpression of cannabinoid receptors CB1 and CB2 correlates with improved prognosis of patients with hepatocellular carcinoma. Cancer Genet Cytogenet 171:31-38.
    • (2006) Cancer Genet Cytogenet , vol.171 , pp. 31-38
    • Xu, X.1    Liu, Y.2    Huang, S.3    Liu, G.4    Xie, C.5    Zhou, J.6    Fan, W.7    Li, Q.8    Wang, Q.9    Zhong, D.10    Miao, X.11
  • 38
    • 0344011538 scopus 로고    scopus 로고
    • Pin1 modulates the structure and function of human RNA polymerase II
    • Xu YX, Hirose Y, Zhou XZ, Lu KP, Manley JL. 2003. Pin1 modulates the structure and function of human RNA polymerase II. Genes Dev 17:2765-2776.
    • (2003) Genes Dev , vol.17 , pp. 2765-2776
    • Xu, Y.X.1    Hirose, Y.2    Zhou, X.Z.3    Lu, K.P.4    Manley, J.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.