메뉴 건너뛰기




Volumn 34, Issue 19, 2015, Pages 2538-2545

Cables1 controls p21/Cip1 protein stability by antagonizing proteasome subunit alpha type 3

Author keywords

[No Author keywords available]

Indexed keywords

CABLES1 PROTEIN, HUMAN; CARRIER PROTEIN; CDK2 PROTEIN, HUMAN; CDK4 PROTEIN, HUMAN; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; PHOSPHOPROTEIN; PROTEASOME; PROTEIN BINDING; PSMA3 PROTEIN, HUMAN; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN;

EID: 84939850800     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.171     Document Type: Article
Times cited : (40)

References (31)
  • 1
    • 67649424560 scopus 로고    scopus 로고
    • P21 in cancer: Intricate networks and multiple activities
    • Abbas T, Dutta A. p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer 2009; 9: 400-414.
    • (2009) Nat Rev Cancer , vol.9 , pp. 400-414
    • Abbas, T.1    Dutta, A.2
  • 2
    • 84871963013 scopus 로고    scopus 로고
    • El-Deiry WS. P21WAF1 and tumourigenesis: 20 years after
    • Warfel NA, El-Deiry WS. p21WAF1 and tumourigenesis: 20 years after. Curr Opin Oncol 2013; 25: 52-58.
    • (2013) Curr Opin Oncol , vol.25 , pp. 52-58
    • Warfel, N.A.1
  • 3
    • 0032530151 scopus 로고    scopus 로고
    • Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins
    • Yu ZK, Gervais JL, Zhang H. Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins. Proc Natl Acad Sci USA 1998; 95: 11324-11329.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11324-11329
    • Yu, Z.K.1    Gervais, J.L.2    Zhang, H.3
  • 4
    • 64049087382 scopus 로고    scopus 로고
    • Phosphorylationdependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB
    • Lin HK, Wang G, Chen Z, Teruya-Feldstein J, Liu Y, Chan CH et al. Phosphorylationdependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB. Nat Cell Biol 2009; 11: 420-432.
    • (2009) Nat Cell Biol , vol.11 , pp. 420-432
    • Lin, H.K.1    Wang, G.2    Chen, Z.3    Teruya-Feldstein, J.4    Liu, Y.5    Chan, C.H.6
  • 6
    • 51949098691 scopus 로고    scopus 로고
    • PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex
    • Abbas T, Sivaprasad U, Terai K, Amador V, Pagano M, Dutta A. PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex. Genes Dev 2008; 22: 2496-2506.
    • (2008) Genes Dev , vol.22 , pp. 2496-2506
    • Abbas, T.1    Sivaprasad, U.2    Terai, K.3    Amador, V.4    Pagano, M.5    Dutta, A.6
  • 7
    • 46649088994 scopus 로고    scopus 로고
    • Phosphorylation of MDMX mediated by Akt leads to stabilization and induces 14-3-3 binding
    • Lopez-Pajares V, Kim MM, Yuan ZM. Phosphorylation of MDMX mediated by Akt leads to stabilization and induces 14-3-3 binding. J Biol Chem 2008; 283: 13707-13713.
    • (2008) J Biol Chem , vol.283 , pp. 13707-13713
    • Lopez-Pajares, V.1    Kim, M.M.2    Yuan, Z.M.3
  • 8
    • 57049133181 scopus 로고    scopus 로고
    • CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation
    • Nishitani H, Shiomi Y, Iida H, Michishita M, Takami T, Tsurimoto T. CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation. J Biol Chem 2008; 283: 29045-29052.
    • (2008) J Biol Chem , vol.283 , pp. 29045-29052
    • Nishitani, H.1    Shiomi, Y.2    Iida, H.3    Michishita, M.4    Takami, T.5    Tsurimoto, T.6
  • 9
    • 34547174700 scopus 로고    scopus 로고
    • APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase
    • Amador V, Ge S, Santamaria PG, Guardavaccaro D, Pagano M. APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase. Mol Cell 2007; 27: 462-473.
    • (2007) Mol Cell , vol.27 , pp. 462-473
    • Amador, V.1    Ge, S.2    Santamaria, P.G.3    Guardavaccaro, D.4    Pagano, M.5
  • 10
    • 0035872863 scopus 로고    scopus 로고
    • A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome
    • Touitou R, Richardson J, Bose S, Nakanishi M, Rivett J, Allday MJ. A degradation signal located in the C-terminus of p21WAF1/CIP1 is a binding site for the C8 alpha-subunit of the 20S proteasome. EMBO J 2001; 20: 2367-2375.
    • (2001) EMBO J , vol.20 , pp. 2367-2375
    • Touitou, R.1    Richardson, J.2    Bose, S.3    Nakanishi, M.4    Rivett, J.5    Allday, M.J.6
  • 12
    • 38949093780 scopus 로고    scopus 로고
    • MDMX promotes proteasomal turnover of p21 at G1 and early S phases independently of, but in cooperation with, MDM2
    • Jin Y, Zeng SX, Sun XX, Lee H, Blattner C, Xiao Z et al. MDMX promotes proteasomal turnover of p21 at G1 and early S phases independently of, but in cooperation with, MDM2. Mol Cell Biol 2008; 28: 1218-1229.
    • (2008) Mol Cell Biol , vol.28 , pp. 1218-1229
    • Jin, Y.1    Zeng, S.X.2    Sun, X.X.3    Lee, H.4    Blattner, C.5    Xiao, Z.6
  • 13
    • 1942437554 scopus 로고    scopus 로고
    • MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53
    • Zhang Z, Wang H, Li M, Agrawal S, Chen X, Zhang R. MDM2 is a negative regulator of p21WAF1/CIP1, independent of p53. J Biol Chem 2004; 279: 16000-16006.
    • (2004) J Biol Chem , vol.279 , pp. 16000-16006
    • Zhang, Z.1    Wang, H.2    Li, M.3    Agrawal, S.4    Chen, X.5    Zhang, R.6
  • 15
    • 0033710860 scopus 로고    scopus 로고
    • Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth
    • Zukerberg LR, Patrick GN, Nikolic M, Humbert S, Wu CL, Lanier LM et al. Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth. Neuron 2000; 26: 633-646.
    • (2000) Neuron , vol.26 , pp. 633-646
    • Zukerberg, L.R.1    Patrick, G.N.2    Nikolic, M.3    Humbert, S.4    Wu, C.L.5    Lanier, L.M.6
  • 16
    • 0035476889 scopus 로고    scopus 로고
    • Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers
    • Wu CL, Kirley SD, Xiao H, Chuang Y, Chung DC, Zukerberg LR. Cables enhances cdk2 tyrosine 15 phosphorylation by Wee1, inhibits cell growth, and is lost in many human colon and squamous cancers. Cancer Res 2001; 61: 7325-7332.
    • (2001) Cancer Res , vol.61 , pp. 7325-7332
    • Wu, C.L.1    Kirley, S.D.2    Xiao, H.3    Chuang, Y.4    Chung, D.C.5    Zukerberg, L.R.6
  • 17
    • 0037169545 scopus 로고    scopus 로고
    • Differential effect of ik3-1/cables on p53- and p73-induced cell death
    • Tsuji K, Mizumoto K, Yamochi T, Nishimoto I, Matsuoka M. Differential effect of ik3-1/cables on p53- and p73-induced cell death. J Biol Chem 2002; 277: 2951-2957.
    • (2002) J Biol Chem , vol.277 , pp. 2951-2957
    • Tsuji, K.1    Mizumoto, K.2    Yamochi, T.3    Nishimoto, I.4    Matsuoka, M.5
  • 18
    • 77955055804 scopus 로고    scopus 로고
    • Cables1 protects p63 from proteasomal degradation to ensure deletion of cells after genotoxic stress
    • Wang N, Guo L, Rueda BR, Tilly JL. Cables1 protects p63 from proteasomal degradation to ensure deletion of cells after genotoxic stress. EMBO Rep 2010; 11: 633-639.
    • (2010) EMBO Rep , vol.11 , pp. 633-639
    • Wang, N.1    Guo, L.2    Rueda, B.R.3    Tilly, J.L.4
  • 19
    • 25144442218 scopus 로고    scopus 로고
    • Increased growth rate, delayed senescense and decreased serum dependence characterize cables-deficient cells
    • Kirley SD, Rueda BR, Chung DC, Zukerberg LR. Increased growth rate, delayed senescense and decreased serum dependence characterize cables-deficient cells. Cancer Biol Ther 2005; 4: 654-658.
    • (2005) Cancer Biol Ther , vol.4 , pp. 654-658
    • Kirley, S.D.1    Rueda, B.R.2    Chung, D.C.3    Zukerberg, L.R.4
  • 20
    • 1642576225 scopus 로고    scopus 로고
    • Loss of cables, a cyclin-dependent kinase regulatory protein, is associated with the development of endometrial hyperplasia and endometrial cancer
    • Zukerberg LR, DeBernardo RL, Kirley SD, D'Apuzzo M, Lynch MP, Littell RD et al. Loss of cables, a cyclin-dependent kinase regulatory protein, is associated with the development of endometrial hyperplasia and endometrial cancer. Cancer Res 2004; 64: 202-208.
    • (2004) Cancer Res , vol.64 , pp. 202-208
    • Zukerberg, L.R.1    Debernardo, R.L.2    Kirley, S.D.3    D'Apuzzo, M.4    Lynch, M.P.5    Littell, R.D.6
  • 22
  • 23
    • 36348961270 scopus 로고    scopus 로고
    • The Cables gene on chromosome 18q is silenced by promoter hypermethylation and allelic loss in human colorectal cancer
    • Park do Y, Sakamoto H, Kirley SD, Ogino S, Kawasaki T, Kwon E et al. The Cables gene on chromosome 18q is silenced by promoter hypermethylation and allelic loss in human colorectal cancer. Am J Pathol 2007; 171: 1509-1519.
    • (2007) Am J Pathol , vol.171 , pp. 1509-1519
    • Park Do, Y.1    Sakamoto, H.2    Kirley, S.D.3    Ogino, S.4    Kawasaki, T.5    Kwon, E.6
  • 24
    • 0037325408 scopus 로고    scopus 로고
    • Loss of cables protein expression in human non-small cell lung cancer: A tissue microarray study
    • Tan D, Kirley S, Li Q, Ramnath N, Slocum HK, Brooks JS et al. Loss of cables protein expression in human non-small cell lung cancer: a tissue microarray study. Hum Pathol 2003; 34: 143-149.
    • (2003) Hum Pathol , vol.34 , pp. 143-149
    • Tan, D.1    Kirley, S.2    Li, Q.3    Ramnath, N.4    Slocum, H.K.5    Brooks, J.S.6
  • 25
    • 84881148535 scopus 로고    scopus 로고
    • Cables1 is a tumor suppressor gene that regulates intestinal tumor progression in Apc(Min) mice
    • Arnason T, Pino MS, Yilmaz O, Kirley SD, Rueda BR, Chung DC et al. Cables1 is a tumor suppressor gene that regulates intestinal tumor progression in Apc(Min) mice. Cancer Biol Ther 2013; 14: 672-678.
    • (2013) Cancer Biol Ther , vol.14 , pp. 672-678
    • Arnason, T.1    Pino, M.S.2    Yilmaz, O.3    Kirley, S.D.4    Rueda, B.R.5    Chung, D.C.6
  • 27
    • 0038219632 scopus 로고    scopus 로고
    • Ras promotes p21(Waf1/Cip1) protein stability via a cyclin D1-imposed block in proteasome-mediated degradation
    • Coleman ML, Marshall CJ, Olson MF. Ras promotes p21(Waf1/Cip1) protein stability via a cyclin D1-imposed block in proteasome-mediated degradation. EMBO J 2003; 22: 2036-2046.
    • (2003) EMBO J , vol.22 , pp. 2036-2046
    • Coleman, M.L.1    Marshall, C.J.2    Olson, M.F.3
  • 28
    • 23844462834 scopus 로고    scopus 로고
    • Cdk2-dependent Inhibition of p21 stability via a C-terminal cyclin-binding motif
    • Zhu H, Nie L, Maki CG. Cdk2-dependent Inhibition of p21 stability via a C-terminal cyclin-binding motif. J Biol Chem 2005; 280: 29282-29288.
    • (2005) J Biol Chem , vol.280 , pp. 29282-29288
    • Zhu, H.1    Nie, L.2    Maki, C.G.3
  • 31
    • 0030747031 scopus 로고    scopus 로고
    • P21 expression as a predictor for favorable prognosis in squamous cell carcinoma of the lung
    • Komiya T, Hosono Y, Hirashima T, Masuda N, Yasumitsu T, Nakagawa K et al. p21 expression as a predictor for favorable prognosis in squamous cell carcinoma of the lung. Clin Cancer Res 1997; 3: 1831-1835.
    • (1997) Clin Cancer Res , vol.3 , pp. 1831-1835
    • Komiya, T.1    Hosono, Y.2    Hirashima, T.3    Masuda, N.4    Yasumitsu, T.5    Nakagawa, K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.