Genetic inactivation of the pancreatitis-inducible gene Nupr1 impairs PanIN formation by modulating KrasG12D-induced senescence

Cell Death and Differentiation

Volumn 21, Issue 10, 2014, Pages 1633-1641

  Grasso, D ^a   Garcia, M N ^a   Hamidi, T ^a   Cano, C ^a   Calvo, E ^b   Lomberk, G ^c   Urrutia, R ^c   Iovanna, J L ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

^b LAVAL UNIVERSITY   (Canada)

^c MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CDKN1B PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; DNA BINDING PROTEIN; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, HUMAN; KRAS2 PROTEIN, MOUSE; NUPR1 PROTEIN, MOUSE; PROTEIN P21; S PHASE KINASE ASSOCIATED PROTEIN; SMALL INTERFERING RNA; TUMOR PROTEIN;

ANIMAL; BIOSYNTHESIS; CELL AGING; CELL LINE; CELL TRANSFORMATION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; KNOCKOUT MOUSE; MOUSE; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; RNA INTERFERENCE; UPREGULATION;

ANIMALS; BETA-GALACTOSIDASE; CARCINOMA, PANCREATIC DUCTAL; CELL AGING; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DNA-BINDING PROTEINS; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; MICE, KNOCKOUT; NEOPLASM PROTEINS; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS P21(RAS); RNA INTERFERENCE; RNA, SMALL INTERFERING; S-PHASE KINASE-ASSOCIATED PROTEINS; UP-REGULATION;

EID: 84939779108     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2014.74     Document Type: Article

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