메뉴 건너뛰기




Volumn 23, Issue 11, 2012, Pages 2226-2234

FOXO3/FKHRL1 is activated by 5-aza-2-deoxycytidine and induces silenced caspase-8 in neuroblastoma

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ATM PROTEIN; CASPASE 8; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; TRANSCRIPTION FACTOR FKHRL1; TUMOR NECROSIS FACTOR;

EID: 84861702434     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E11-06-0535     Document Type: Article
Times cited : (24)

References (38)
  • 1
    • 41849087003 scopus 로고    scopus 로고
    • FOXO animal models reveal a variety of diverse roles for FOXO transcription factors
    • Arden KC (2008). FOXO animal models reveal a variety of diverse roles for FOXO transcription factors. Oncogene 27, 2345-2350.
    • (2008) Oncogene , vol.27 , pp. 2345-2350
    • Arden, K.C.1
  • 3
    • 65949097277 scopus 로고    scopus 로고
    • Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis
    • Barbero S et al. (2009). Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis. Cancer Res 69, 3755-3763.
    • (2009) Cancer Res , vol.69 , pp. 3755-3763
    • Barbero, S.1
  • 4
    • 0036629251 scopus 로고    scopus 로고
    • Cell cycle and death control: Long live Forkheads
    • DOI 10.1016/S0968-0004(02)02113-8, PII S0968000402021138
    • Burgering BM, Kops GJ (2002). Cell cycle and death control: long live Forkheads. Trends Biochem Sci 27, 352-360. (Pubitemid 34756518)
    • (2002) Trends in Biochemical Sciences , vol.27 , Issue.7 , pp. 352-360
    • Burgering, B.M.T.1    Kops, G.J.P.L.2
  • 5
    • 41849128523 scopus 로고    scopus 로고
    • The FoxO code
    • DOI 10.1038/onc.2008.21, PII ONC200821
    • Calnan DR, Brunet A (2008). The FoxO code. Oncogene 27, 2276-2288. (Pubitemid 351501779)
    • (2008) Oncogene , vol.27 , Issue.16 , pp. 2276-2288
    • Calnan, D.R.1    Brunet, A.2
  • 6
    • 0034609737 scopus 로고    scopus 로고
    • Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
    • Dijkers PF, Medema RH, Lammers JW, Koenderman L, Coffer PJ (2000). Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1. Curr Biol 10, 1201-1204.
    • (2000) Curr Biol , vol.10 , pp. 1201-1204
    • Dijkers, P.F.1    Medema, R.H.2    Lammers, J.W.3    Koenderman, L.4    Coffer, P.J.5
  • 7
    • 84855607470 scopus 로고    scopus 로고
    • The ATM protein kinase and cellular redox signaling: Beyond the DNA damage response
    • Ditch S, Paull TT (2012). The ATM protein kinase and cellular redox signaling: beyond the DNA damage response. Trends Biochem Sci 37, 15-22.
    • (2012) Trends Biochem Sci , vol.37 , pp. 15-22
    • Ditch, S.1    Paull, T.T.2
  • 9
    • 0033646843 scopus 로고    scopus 로고
    • Resistance to TRAIL-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression
    • Eggert A, Grotzer MA, Zuzak TJ, Wiewrodt BR, Ikegaki N, Brodeur GM (2000). Resistance to TRAIL-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression. Med Pediatr Oncol 35, 603-607.
    • (2000) Med Pediatr Oncol , vol.35 , pp. 603-607
    • Eggert, A.1    Grotzer, M.A.2    Zuzak, T.J.3    Wiewrodt, B.R.4    Ikegaki, N.5    Brodeur, G.M.6
  • 11
    • 34447550085 scopus 로고    scopus 로고
    • Activation of the kinase activity of ATM by retinoic acid is required for CREB-dependent differentiation of neuroblastoma cells
    • DOI 10.1074/jbc.M609628200
    • Fernandes ND, Sun Y, Price BD (2007). Activation of the kinase activity of ATM by retinoic acid is required for CREB-dependent differentiation of neuroblastoma cells. J Biol Chem 282, 16577-16584. (Pubitemid 47100398)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.22 , pp. 16577-16584
    • Fernandes, N.D.1    Sun, Y.2    Price, B.D.3
  • 12
    • 84889271499 scopus 로고    scopus 로고
    • IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway
    • DOI 10.1038/sj/onc/1205255
    • Fulda S, Debatin KM (2002). IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway. Oncogene 21, 2295-2308. (Pubitemid 34407289)
    • (2002) Oncogene , vol.21 , Issue.15 , pp. 2295-2308
    • Fulda, S.1    Debatin, K.-M.2
  • 13
    • 0035855626 scopus 로고    scopus 로고
    • Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer
    • DOI 10.1038/sj.onc.1204750
    • Fulda S, Kufer MU, Meyer E, Van Valen F, Dockhorn-Dworniczak B, Debatin KM (2001). Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer. Oncogene 20, 5865-5877. (Pubitemid 32937956)
    • (2001) Oncogene , vol.20 , Issue.41 , pp. 5865-5877
    • Fulda, S.1    Kufer, M.U.2    Meyer, E.3    Van Valen, F.4    Dockhorn-Dworniczak, B.5    Debatin, K.-M.6
  • 14
    • 33750561936 scopus 로고    scopus 로고
    • Loss of caspase-8 expression does not correlate with MYCN amplification, aggressive disease, or prognosis in neuroblastoma
    • DOI 10.1158/0008-5472.CAN-05-4079
    • Fulda S, Poremba C, Berwanger B, Hacker S, Eilers M, Christiansen H, Hero B, Debatin KM (2006). Loss of caspase-8 expression does not correlate with MYCN amplification, aggressive disease, or prognosis in neuroblastoma. Cancer Res 66, 10016-10023. (Pubitemid 44672054)
    • (2006) Cancer Research , vol.66 , Issue.20 , pp. 10016-10023
    • Fulda, S.1    Poremba, C.2    Berwanger, B.3    Hacker, S.4    Eilers, M.5    Christiansen, H.6    Hero, B.7    Debatin, K.-M.8
  • 15
    • 41849093037 scopus 로고    scopus 로고
    • The role of FoxO in the regulation of metabolism
    • DOI 10.1038/onc.2008.25, PII ONC200825
    • Gross DN, van den Heuvel AP, Birnbaum MJ (2008). The role of FoxO in the regulation of metabolism. Oncogene 27, 2320-2336. (Pubitemid 351501783)
    • (2008) Oncogene , vol.27 , Issue.16 , pp. 2320-2336
    • Gross, D.N.1    Van Den, H.A.P.J.2    Birnbaum, M.J.3
  • 16
    • 77951243665 scopus 로고    scopus 로고
    • The anti-apoptotic protein CL2L1/Bcl-xL is neutralized by pro-apoptotic PMAIP1/Noxa in neuroblastoma, thereby determining bortezomib sensitivity independent of prosurvival MCL1 expression
    • Hagenbuchner J, Ausserlechner MJ, Porto V, David R, Meister B, Bodner M, Villunger A, Geiger K, Obexer P (2010). The anti-apoptotic protein CL2L1/Bcl-xL is neutralized by pro-apoptotic PMAIP1/Noxa in neuroblastoma, thereby determining bortezomib sensitivity independent of prosurvival MCL1 expression. J Biol Chem 285, 6904-6912.
    • (2010) J Biol Chem , vol.285 , pp. 6904-6912
    • Hagenbuchner, J.1    Ausserlechner, M.J.2    Porto, V.3    David, R.4    Meister, B.5    Bodner, M.6    Villunger, A.7    Geiger, K.8    Obexer, P.9
  • 18
    • 41849108086 scopus 로고    scopus 로고
    • Many forks in the path: Cycling with FoxO
    • DOI 10.1038/onc.2008.23, PII ONC200823
    • Ho KK, Myatt SS, Lam EW (2008). Many forks in the path: cycling with FoxO. Oncogene 27, 2300-2311. (Pubitemid 351501781)
    • (2008) Oncogene , vol.27 , Issue.16 , pp. 2300-2311
    • Ho, K.K.1    Myatt, S.S.2    Lam, E.W.-F.3
  • 19
    • 0034662625 scopus 로고    scopus 로고
    • Loss of caspase-8 expression in highly malignant human neuroblastoma cells correlates with resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis
    • Hopkins-Donaldson S, Bodmer JL, Bourloud KB, Brognara CB, Tschopp J, Gross N (2000). Loss of caspase-8 expression in highly malignant human neuroblastoma cells correlates with resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis. Cancer Res 60, 4315-4319. (Pubitemid 32103601)
    • (2000) Cancer Research , vol.60 , Issue.16 , pp. 4315-4319
    • Hopkins-Donaldson, S.1    Bodmer, J.-L.2    Bourloud, K.B.3    Brognara, C.B.4    Tschopp, J.5    Gross, N.6
  • 20
    • 43749104015 scopus 로고    scopus 로고
    • Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells
    • Jiang M, Zhu K, Grenet J, Lahti JM (2008). Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells. Biochim Biophys Acta 1783, 1055-1067.
    • (2008) Biochim Biophys Acta , vol.1783 , pp. 1055-1067
    • Jiang, M.1    Zhu, K.2    Grenet, J.3    Lahti, J.M.4
  • 22
    • 16844374910 scopus 로고    scopus 로고
    • Genetic and pharmacologic identification of Akt as a mediator of brain-derived neurotrophic factor/TrkB rescue of neuroblastoma cells from chemotherapy-induced cell death
    • DOI 10.1158/0008-5472.CAN-04-3606
    • Li Z, Jaboin J, Dennis PA, Thiele CJ (2005). Genetic and pharmacologic identification of Akt as a mediator of brain-derived neurotrophic factor/TrkB rescue of neuroblastoma cells from chemotherapy-induced cell death. Cancer Res 65, 2070-2075. (Pubitemid 40490110)
    • (2005) Cancer Research , vol.65 , Issue.6 , pp. 2070-2075
    • Li, Z.1    Jaboin, J.2    Dennis, P.A.3    Thiele, C.J.4
  • 23
    • 28244486026 scopus 로고    scopus 로고
    • Automatic telomere length measurements in interphase nuclei by IQ-FISH
    • DOI 10.1002/cyto.a.20190
    • Narath R, Lorch T, Greulich-Bode KM, Boukamp P, Ambros PF (2005). Automatic telomere length measurements in interphase nuclei by IQ-FISH. Cytometry A 68, 113-120. (Pubitemid 41705204)
    • (2005) Cytometry Part A , vol.68 , Issue.2 , pp. 113-120
    • Narath, R.1    Lorch, T.2    Greulich-Bode, K.M.3    Boukamp, P.4    Ambros, P.F.5
  • 24
    • 33847077943 scopus 로고    scopus 로고
    • FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells
    • Obexer P, Geiger K, Ambros PF, Meister B, Ausserlechner MJ (2007). FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells. Cell Death Differ 14, 534-547.
    • (2007) Cell Death Differ , vol.14 , pp. 534-547
    • Obexer, P.1    Geiger, K.2    Ambros, P.F.3    Meister, B.4    Ausserlechner, M.J.5
  • 26
    • 33846694864 scopus 로고    scopus 로고
    • Activation of Akt predicts poor outcome in neuroblastoma
    • DOI 10.1158/0008-5472.CAN-06-2201
    • Opel D, Poremba C, Simon T, Debatin KM, Fulda S (2007). Activation of Akt predicts poor outcome in neuroblastoma. Cancer Res 67, 735-745. (Pubitemid 46192214)
    • (2007) Cancer Research , vol.67 , Issue.2 , pp. 735-745
    • Opel, D.1    Poremba, C.2    Simon, T.3    Debatin, K.-M.4    Fulda, S.5
  • 27
    • 37849026412 scopus 로고    scopus 로고
    • DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B
    • Palii SS, Van Emburgh BO, Sankpal UT, Brown KD, Robertson KD (2008). DNA methylation inhibitor 5-Aza-2'-deoxycytidine induces reversible genome-wide DNA damage that is distinctly influenced by DNA methyltransferases 1 and 3B. Mol Cell Biol 28, 752-771.
    • (2008) Mol Cell Biol , vol.28 , pp. 752-771
    • Palii, S.S.1    Van Emburgh, B.O.2    Sankpal, U.T.3    Brown, K.D.4    Robertson, K.D.5
  • 28
    • 38649093611 scopus 로고    scopus 로고
    • Neuroblastoma: Biology, Prognosis, and Treatment
    • DOI 10.1016/j.pcl.2007.10.014, PII S0031395507001575
    • Park JR, Eggert A, Caron H (2008). Neuroblastoma: biology, prognosis, and treatment. Pediatr Clin North Am 55, 97-120. (Pubitemid 351173188)
    • (2008) Pediatric Clinics of North America , vol.55 , Issue.1 , pp. 97-120
    • Park, J.R.1    Eggert, A.2    Caron, H.3
  • 30
    • 23944475155 scopus 로고    scopus 로고
    • Insulin-like growth factor-I induces the phosphorylation and nuclear exclusion of forkhead transcription factors in human neuroblastoma cells
    • DOI 10.1007/s10495-005-0429-y
    • Schwab TS, Madison BB, Grauman AR, Feldman EL (2005). Insulin-like growth factor-I induces the phosphorylation and nuclear exclusion of forkhead transcription factors in human neuroblastoma cells. Apoptosis 10, 831-840. (Pubitemid 41187081)
    • (2005) Apoptosis , vol.10 , Issue.4 , pp. 831-840
    • Schwab, T.S.1    Madison, B.B.2    Grauman, A.R.3    Feldman, E.L.4
  • 32
    • 22944479314 scopus 로고    scopus 로고
    • JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3
    • DOI 10.1083/jcb.200409117
    • Sunayama J, Tsuruta F, Masuyama N, Gotoh Y (2005). JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3. J Cell Biol 170, 295-304. (Pubitemid 41043811)
    • (2005) Journal of Cell Biology , vol.170 , Issue.2 , pp. 295-304
    • Sunayama, J.1    Tsuruta, F.2    Masuyama, N.3    Gotoh, Y.4
  • 35
    • 43149111604 scopus 로고    scopus 로고
    • Functional interaction between FOXO3a and ATM regulates DNA damage response
    • Tsai WB, Chung YM, Takahashi Y, Xu Z, Hu MC (2008). Functional interaction between FOXO3a and ATM regulates DNA damage response. Nat Cell Biol 10, 460-467.
    • (2008) Nat Cell Biol , vol.10 , pp. 460-467
    • Tsai, W.B.1    Chung, Y.M.2    Takahashi, Y.3    Xu, Z.4    Hu, M.C.5
  • 37
    • 54449092731 scopus 로고    scopus 로고
    • Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells
    • Yalcin S et al. (2008). Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells. J Biol Chem 283, 25692-25705.
    • (2008) J Biol Chem , vol.283 , pp. 25692-25705
    • Yalcin, S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.