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Volumn 30, Issue , 2015, Pages iv86-iv95

Prognostic clinical and molecular biomarkers of renal disease in type 2 diabetes

(12)  Pena, Michelle J a   De Zeeuw, Dick a   Mischak, Harald b,c   Jankowski, Joachim d   Oberbauer, Rainer e   Woloszczuk, Wolfgang f   Benner, Jacqueline f   Dallmann, Guido g   Mayer, Bernd h   Mayer, Gert i   Rossing, Peter j,k,l   Lambers Heerspink, Hiddo J a  


Author keywords

biomarker panels; CKD; metabolomics; novel biomarkers; proteomics

Indexed keywords

BIOLOGICAL MARKER;

EID: 84939633635     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfv252     Document Type: Review
Times cited : (35)

References (100)
  • 1
    • 84898602820 scopus 로고    scopus 로고
    • Changes in diabetes-related complications in the United States, 1990-2010
    • Gregg EW, Li Y, Wang J et al. Changes in diabetes-related complications in the United States, 1990-2010. N Engl J Med 2014; 370: 1514-1523
    • (2014) N Engl J Med , vol.370 , pp. 1514-1523
    • Gregg, E.W.1    Li, Y.2    Wang, J.3
  • 2
    • 84921893999 scopus 로고    scopus 로고
    • National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD 16 June 2015, date last accessed
    • United States Renal Data System, 2014 Annual Data Report: Epidemiology of Kidney Disease in the United States. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2014. http://www.usrds.org/adr.aspx (16 June 2015, date last accessed)
    • (2014) 2014 Annual Data Report: Epidemiology of Kidney Disease in the United States
  • 3
    • 84891829578 scopus 로고    scopus 로고
    • The economic burden of progressive chronic kidney disease among patients with type 2 diabetes
    • Vupputuri S, Kimes TM, Calloway MO et al. The economic burden of progressive chronic kidney disease among patients with type 2 diabetes. J Diabetes Complications 2014; 28: 10-16
    • (2014) J Diabetes Complications , vol.28 , pp. 10-16
    • Vupputuri, S.1    Kimes, T.M.2    Calloway, M.O.3
  • 4
    • 84878716576 scopus 로고    scopus 로고
    • Kidney Disease: Improving Global Outcomes Chronic Kidney Disease Guideline Development Work Group Members. Evaluation and management of chronic kidney disease: Synopsis of the kidney disease: Improving global outcomes 2012 clinical practice guideline
    • Stevens PE, Levin A, Kidney Disease: Improving Global Outcomes Chronic Kidney Disease Guideline Development Work Group Members. Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline. Ann Intern Med 2013; 158: 825-830
    • (2013) Ann Intern Med , vol.158 , pp. 825-830
    • Stevens, P.E.1    Levin, A.2
  • 5
    • 6844252285 scopus 로고    scopus 로고
    • Heterogeneous nature of microalbuminuria in NIDDM: Studies of endothelial function and renal structure
    • Fioretto P, Stehouwer CD, Mauer M et al. Heterogeneous nature of microalbuminuria in NIDDM: studies of endothelial function and renal structure. Diabetologia 1998; 41: 233-236
    • (1998) Diabetologia , vol.41 , pp. 233-236
    • Fioretto, P.1    Stehouwer, C.D.2    Mauer, M.3
  • 6
    • 84875598343 scopus 로고    scopus 로고
    • Diabetic nephropathy: Traditional to proteomic markers
    • Moresco RN, Sangoi MB, De Carvalho JA et al. Diabetic nephropathy: traditional to proteomic markers. Clin Chim Acta 2013; 421: 17-30
    • (2013) Clin Chim Acta , vol.421 , pp. 17-30
    • Moresco, R.N.1    Sangoi, M.B.2    De Carvalho, J.A.3
  • 7
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998; 352: 837-853
    • (1998) Lancet , vol.352 , pp. 837-853
  • 8
    • 45149133036 scopus 로고    scopus 로고
    • Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
    • ADVANCE Collaborative GroupPatel A, MacMahon S et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008; 358: 2560-2572
    • (2008) N Engl J Med , vol.358 , pp. 2560-2572
    • Patel, A.1    MacMahon, S.2
  • 9
    • 77957742069 scopus 로고    scopus 로고
    • Severe hypoglycemia and risks of vascular events and death
    • Zoungas S, Patel A, Chalmers J et al. Severe hypoglycemia and risks of vascular events and death. N Engl J Med 2010; 363: 1410-1418
    • (2010) N Engl J Med , vol.363 , pp. 1410-1418
    • Zoungas, S.1    Patel, A.2    Chalmers, J.3
  • 10
    • 82455174130 scopus 로고    scopus 로고
    • Association between glycemic control and adverse outcomes in people with diabetes mellitus and chronic kidney disease: A population-based cohort study
    • Shurraw S, Hemmelgarn B, Lin M et al. Association between glycemic control and adverse outcomes in people with diabetes mellitus and chronic kidney disease: a population-based cohort study. Arch Intern Med 2011; 171: 1920-1927
    • (2011) Arch Intern Med , vol.171 , pp. 1920-1927
    • Shurraw, S.1    Hemmelgarn, B.2    Lin, M.3
  • 11
    • 84908206119 scopus 로고    scopus 로고
    • Blood pressure and pulse pressure effects on renal outcomes in the Veterans Affairs Diabetes Trial (VADT)
    • Anderson RJ, Bahn GD, Emanuele NV et al. Blood pressure and pulse pressure effects on renal outcomes in the Veterans Affairs Diabetes Trial (VADT). Diabetes Care 2014; 37: 2782-2788
    • (2014) Diabetes Care , vol.37 , pp. 2782-2788
    • Anderson, R.J.1    Bahn, G.D.2    Emanuele, N.V.3
  • 12
    • 0017164014 scopus 로고
    • Effect of antihypertensive treatment on urinary albumin excretion, glomerular filtration rate, and renal plasma flow in patients with essential hypertension
    • Pedersen EB, Mogensen CE. Effect of antihypertensive treatment on urinary albumin excretion, glomerular filtration rate, and renal plasma flow in patients with essential hypertension. Scand J Clin Lab Invest 1976; 36: 231-237
    • (1976) Scand J Clin Lab Invest , vol.36 , pp. 231-237
    • Pedersen, E.B.1    Mogensen, C.E.2
  • 13
    • 0020549706 scopus 로고
    • Early aggressive antihypertensive treatment reduces rate of decline in kidney function in diabetic nephropathy
    • Parving HH, Andersen AR, Smidt UM et al. Early aggressive antihypertensive treatment reduces rate of decline in kidney function in diabetic nephropathy. Lancet 1983; 1: 1175-1179
    • (1983) Lancet , vol.1 , pp. 1175-1179
    • Parving, H.H.1    Andersen, A.R.2    Smidt, U.M.3
  • 14
    • 7444221237 scopus 로고    scopus 로고
    • Preventing microalbuminuria in type 2 diabetes
    • Ruggenenti P, Fassi A, Ilieva AP et al. Preventing microalbuminuria in type 2 diabetes. N Engl J Med 2004; 351: 1941-1951
    • (2004) N Engl J Med , vol.351 , pp. 1941-1951
    • Ruggenenti, P.1    Fassi, A.2    Ilieva, A.P.3
  • 15
    • 79952373965 scopus 로고    scopus 로고
    • Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes
    • Haller H, Ito S, Izzo JL, Jr et al. Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes. N Engl J Med 2011; 364: 907-917
    • (2011) N Engl J Med , vol.364 , pp. 907-917
    • Haller, H.1    Ito, S.2    Izzo, J.L.3
  • 16
    • 0035922444 scopus 로고    scopus 로고
    • The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes
    • Parving HH, Lehnert H, Brochner-Mortensen J et al. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N Engl J Med 2001; 345: 870-878
    • (2001) N Engl J Med , vol.345 , pp. 870-878
    • Parving, H.H.1    Lehnert, H.2    Brochner-Mortensen, J.3
  • 17
    • 0035922441 scopus 로고    scopus 로고
    • Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy
    • Brenner BM, Cooper ME, de Zeeuw D et al. Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. N Engl J Med 2001; 345: 861-869
    • (2001) N Engl J Med , vol.345 , pp. 861-869
    • Brenner, B.M.1    Cooper, M.E.2    De Zeeuw, D.3
  • 18
    • 0035922447 scopus 로고    scopus 로고
    • Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
    • Lewis EJ, Hunsicker LG, Clarke WR et al. Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. N Engl J Med 2001; 345: 851-860
    • (2001) N Engl J Med , vol.345 , pp. 851-860
    • Lewis, E.J.1    Hunsicker, L.G.2    Clarke, W.R.3
  • 19
    • 4344683381 scopus 로고    scopus 로고
    • Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): Multicentre randomised placebo-controlled trial
    • Colhoun HM, Betteridge DJ, Durrington PN et al. Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial. Lancet 2004; 364: 685-696
    • (2004) Lancet , vol.364 , pp. 685-696
    • Colhoun, H.M.1    Betteridge, D.J.2    Durrington, P.N.3
  • 20
    • 84906791388 scopus 로고    scopus 로고
    • Effects of lowering LDL cholesterol on progression of kidney disease
    • Haynes R, Lewis D, Emberson J et al. Effects of lowering LDL cholesterol on progression of kidney disease. J Am Soc Nephrol 2014; 25: 1825-1833
    • (2014) J Am Soc Nephrol , vol.25 , pp. 1825-1833
    • Haynes, R.1    Lewis, D.2    Emberson, J.3
  • 21
    • 84924081459 scopus 로고    scopus 로고
    • Renal effects of atorvastatin and rosuvastatin in patients with diabetes who have progressive renal disease (PLANET I): A randomised clinical trial
    • de Zeeuw D, Anzalone DA, Cain VA et al. Renal effects of atorvastatin and rosuvastatin in patients with diabetes who have progressive renal disease (PLANET I): a randomised clinical trial. Lancet Diabetes Endocrinol 2015; 3: 181-190
    • (2015) Lancet Diabetes Endocrinol , vol.3 , pp. 181-190
    • De Zeeuw, D.1    Anzalone, D.A.2    Cain, V.A.3
  • 22
    • 4344713002 scopus 로고    scopus 로고
    • Anemia and end-stage renal disease in patients with type 2 diabetes and nephropathy
    • Mohanram A, Zhang Z, Shahinfar S et al. Anemia and end-stage renal disease in patients with type 2 diabetes and nephropathy. Kidney Int 2004; 66: 1131-1138
    • (2004) Kidney Int , vol.66 , pp. 1131-1138
    • Mohanram, A.1    Zhang, Z.2    Shahinfar, S.3
  • 23
    • 79959709376 scopus 로고    scopus 로고
    • Effect of a reduction in uric acid on renal outcomes during losartan treatment: A post hoc analysis of the reduction of endpoints in non-insulin-dependent diabetes mellitus with the Angiotensin II Antagonist Losartan Trial
    • Miao Y, Ottenbros SA, Laverman GD et al. Effect of a reduction in uric acid on renal outcomes during losartan treatment: a post hoc analysis of the reduction of endpoints in non-insulin-dependent diabetes mellitus with the Angiotensin II Antagonist Losartan Trial. Hypertension 2011; 58: 2-7
    • (2011) Hypertension , vol.58 , pp. 2-7
    • Miao, Y.1    Ottenbros, S.A.2    Laverman, G.D.3
  • 24
    • 84859060635 scopus 로고    scopus 로고
    • Serum uric acid levels and incident chronic kidney disease in patients with type 2 diabetes and preserved kidney function
    • Zoppini G, Targher G, Chonchol M et al. Serum uric acid levels and incident chronic kidney disease in patients with type 2 diabetes and preserved kidney function. Diabetes Care 2012; 35: 99-104
    • (2012) Diabetes Care , vol.35 , pp. 99-104
    • Zoppini, G.1    Targher, G.2    Chonchol, M.3
  • 25
    • 61449183458 scopus 로고    scopus 로고
    • Is hyperfiltration associated with the future risk of developing diabetic nephropathy? A meta-analysis
    • Magee GM, Bilous RW, Cardwell CR et al. Is hyperfiltration associated with the future risk of developing diabetic nephropathy? A meta-analysis. Diabetologia 2009; 52: 691-697
    • (2009) Diabetologia , vol.52 , pp. 691-697
    • Magee, G.M.1    Bilous, R.W.2    Cardwell, C.R.3
  • 26
    • 84857112763 scopus 로고    scopus 로고
    • Glomerular hyperfiltration and increased glomerular filtration surface are associated with renal function decline in normo- and microalbuminuric type 2 diabetes
    • Moriya T, Tsuchiya A, Okizaki S et al. Glomerular hyperfiltration and increased glomerular filtration surface are associated with renal function decline in normo- and microalbuminuric type 2 diabetes. Kidney Int 2012; 81: 486-493
    • (2012) Kidney Int , vol.81 , pp. 486-493
    • Moriya, T.1    Tsuchiya, A.2    Okizaki, S.3
  • 27
    • 0029827650 scopus 로고    scopus 로고
    • Development and progression of renal disease in Pima Indians with non-insulin-dependent diabetes mellitus
    • Diabetic Renal Disease Study Group
    • Nelson RG, Bennett PH, Beck GJ et al. Development and progression of renal disease in Pima Indians with non-insulin-dependent diabetes mellitus. Diabetic Renal Disease Study Group. N Engl J Med 1996; 335: 1636-1642
    • (1996) N Engl J Med , vol.335 , pp. 1636-1642
    • Nelson, R.G.1    Bennett, P.H.2    Beck, G.J.3
  • 28
    • 0031770310 scopus 로고    scopus 로고
    • Hyperfiltration in African-American patients with type 2 diabetes. Cross-sectional and longitudinal data
    • Chaiken RL, Eckert-Norton M, Bard M et al. Hyperfiltration in African-American patients with type 2 diabetes. Cross-sectional and longitudinal data. Diabetes Care 1998; 21: 2129-2134
    • (1998) Diabetes Care , vol.21 , pp. 2129-2134
    • Chaiken, R.L.1    Eckert-Norton, M.2    Bard, M.3
  • 29
    • 84866656037 scopus 로고    scopus 로고
    • Glomerular hyperfiltration and renal disease progression in type 2 diabetes
    • Ruggenenti P, Porrini EL, Gaspari F et al. Glomerular hyperfiltration and renal disease progression in type 2 diabetes. Diabetes Care 2012; 35: 2061-2068
    • (2012) Diabetes Care , vol.35 , pp. 2061-2068
    • Ruggenenti, P.1    Porrini, E.L.2    Gaspari, F.3
  • 30
    • 0027525040 scopus 로고
    • Renal renin-angiotensin system in diabetes: Functional, immunohistochemical, and molecular biological correlations
    • Anderson S, Jung FF, Ingelfinger JR. Renal renin-angiotensin system in diabetes: functional, immunohistochemical, and molecular biological correlations. Am J Physiol 1993; 265: F477-F486
    • (1993) Am J Physiol , vol.265 , pp. F477-F486
    • Anderson, S.1    Jung, F.F.2    Ingelfinger, J.R.3
  • 31
    • 0037804206 scopus 로고    scopus 로고
    • GLUT-1 overexpression: Link between hemodynamic and metabolic factors in glomerular injury?
    • Gnudi L, Viberti G, Raij L et al. GLUT-1 overexpression: link between hemodynamic and metabolic factors in glomerular injury? Hypertension 2003; 42: 19-24
    • (2003) Hypertension , vol.42 , pp. 19-24
    • Gnudi, L.1    Viberti, G.2    Raij, L.3
  • 32
    • 84921772366 scopus 로고    scopus 로고
    • The impact of hyperfiltration on the diabetic kidney
    • Premaratne E, Verma S, Ekinci EI et al. The impact of hyperfiltration on the diabetic kidney. Diabetes Metab 2015; 41: 5-17
    • (2015) Diabetes Metab , vol.41 , pp. 5-17
    • Premaratne, E.1    Verma, S.2    Ekinci, E.I.3
  • 33
    • 33750736645 scopus 로고    scopus 로고
    • How does proteinuria cause progressive renal damage?
    • Abbate M, Zoja C, Remuzzi G. How does proteinuria cause progressive renal damage? J Am Soc Nephrol 2006; 17: 2974-2984
    • (2006) J Am Soc Nephrol , vol.17 , pp. 2974-2984
    • Abbate, M.1    Zoja, C.2    Remuzzi, G.3
  • 34
    • 84868540565 scopus 로고    scopus 로고
    • Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: A meta-analysis
    • Fox CS, Matsushita K, Woodward M et al. Associations of kidney disease measures with mortality and end-stage renal disease in individuals with and without diabetes: a meta-analysis. Lancet 2012; 380: 1662-1673
    • (2012) Lancet , vol.380 , pp. 1662-1673
    • Fox, C.S.1    Matsushita, K.2    Woodward, M.3
  • 35
    • 77649201176 scopus 로고    scopus 로고
    • Similar renal decline in diabetic and non-diabetic patients with comparable levels of albuminuria
    • Lorenzo V, Saracho R, Zamora J et al. Similar renal decline in diabetic and non-diabetic patients with comparable levels of albuminuria. Nephrol Dial Transplant 2010; 25: 835-841
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 835-841
    • Lorenzo, V.1    Saracho, R.2    Zamora, J.3
  • 36
    • 84922764517 scopus 로고    scopus 로고
    • Microalbuminuria: A parameter that has changed diabetes care
    • Parving HH, Persson F, Rossing P. Microalbuminuria: a parameter that has changed diabetes care. Diabetes Res Clin Pract 2015; 107: 1-8
    • (2015) Diabetes Res Clin Pract , vol.107 , pp. 1-8
    • Parving, H.H.1    Persson, F.2    Rossing, P.3
  • 37
    • 84904970447 scopus 로고    scopus 로고
    • Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy
    • Siwy J, Schanstra JP, Argiles A et al. Multicentre prospective validation of a urinary peptidome-based classifier for the diagnosis of type 2 diabetic nephropathy. Nephrol Dial Transplant 2014; 29: 1563-1570
    • (2014) Nephrol Dial Transplant , vol.29 , pp. 1563-1570
    • Siwy, J.1    Schanstra, J.P.2    Argiles, A.3
  • 38
    • 84857938428 scopus 로고    scopus 로고
    • Circulating TNF receptors 1 and 2 predict ESRD in type 2 diabetes
    • Niewczas MA, Gohda T, Skupien J et al. Circulating TNF receptors 1 and 2 predict ESRD in type 2 diabetes. J Am Soc Nephrol 2012; 23: 507-515
    • (2012) J Am Soc Nephrol , vol.23 , pp. 507-515
    • Niewczas, M.A.1    Gohda, T.2    Skupien, J.3
  • 39
    • 67549118453 scopus 로고    scopus 로고
    • Urinary monocyte chemoattractant protein-1 (MCP-1) and connective tissue growth factor (CCN2) as prognostic markers for progression of diabetic nephropathy
    • Tam FW, Riser BL, Meeran K et al. Urinary monocyte chemoattractant protein-1 (MCP-1) and connective tissue growth factor (CCN2) as prognostic markers for progression of diabetic nephropathy. Cytokine 2009; 47: 37-42
    • (2009) Cytokine , vol.47 , pp. 37-42
    • Tam, F.W.1    Riser, B.L.2    Meeran, K.3
  • 40
    • 84858745182 scopus 로고    scopus 로고
    • High YKL-40 levels predict mortality in patients with type 2 diabetes
    • Persson F, Rathcke CN, Gall MA et al. High YKL-40 levels predict mortality in patients with type 2 diabetes. Diabetes Res Clin Pract 2012; 96: 84-89
    • (2012) Diabetes Res Clin Pract , vol.96 , pp. 84-89
    • Persson, F.1    Rathcke, C.N.2    Gall, M.A.3
  • 41
    • 84868100661 scopus 로고    scopus 로고
    • Growth-differentiation factor 15 predicts worsening of albuminuria in patients with type 2 diabetes
    • Hellemons ME, Mazagova M, Gansevoort RT et al. Growth-differentiation factor 15 predicts worsening of albuminuria in patients with type 2 diabetes. Diabetes Care 2012; 35: 2340-2346
    • (2012) Diabetes Care , vol.35 , pp. 2340-2346
    • Hellemons, M.E.1    Mazagova, M.2    Gansevoort, R.T.3
  • 42
    • 84866372250 scopus 로고    scopus 로고
    • Measuring urinary tubular biomarkers in type 2 diabetes does not add prognostic value beyond established risk factors
    • Conway BR, Manoharan D, Manoharan D et al. Measuring urinary tubular biomarkers in type 2 diabetes does not add prognostic value beyond established risk factors. Kidney Int 2012; 82: 812-818
    • (2012) Kidney Int , vol.82 , pp. 812-818
    • Conway, B.R.1    Manoharan, D.2    Manoharan, D.3
  • 43
    • 84916198679 scopus 로고    scopus 로고
    • Association of urinary KIM-1, L-FABP, NAG and NGAL with incident end-stage renal disease and mortality in American Indians with type 2 diabetes mellitus
    • Fufaa GD, Weil EJ, Nelson RG et al. Association of urinary KIM-1, L-FABP, NAG and NGAL with incident end-stage renal disease and mortality in American Indians with type 2 diabetes mellitus. Diabetologia 2015; 58: 188-198
    • (2015) Diabetologia , vol.58 , pp. 188-198
    • Fufaa, G.D.1    Weil, E.J.2    Nelson, R.G.3
  • 44
    • 79957614666 scopus 로고    scopus 로고
    • Mapping of molecular pathways, biomarkers and drug targets for diabetic nephropathy
    • Fechete R, Heinzel A, Perco P et al. Mapping of molecular pathways, biomarkers and drug targets for diabetic nephropathy. Proteomics Clin Appl 2011; 5: 354-366
    • (2011) Proteomics Clin Appl , vol.5 , pp. 354-366
    • Fechete, R.1    Heinzel, A.2    Perco, P.3
  • 45
    • 84926528922 scopus 로고    scopus 로고
    • Elevation of circulating TNF receptors 1 and 2 increases the risk of end-stage renal disease in American Indians with type 2 diabetes
    • Pavkov ME, Nelson RG, Knowler WC et al. Elevation of circulating TNF receptors 1 and 2 increases the risk of end-stage renal disease in American Indians with type 2 diabetes. Kidney Int 2015; 87: 812-819
    • (2015) Kidney Int , vol.87 , pp. 812-819
    • Pavkov, M.E.1    Nelson, R.G.2    Knowler, W.C.3
  • 46
    • 84906656078 scopus 로고    scopus 로고
    • Synergism between circulating tumor necrosis factor receptor 2 and HbA(1c) in determining renal decline during 5-18 years of follow-up in patients with type 1 diabetes and proteinuria
    • Skupien J, Warram JH, Niewczas MA et al. Synergism between circulating tumor necrosis factor receptor 2 and HbA(1c) in determining renal decline during 5-18 years of follow-up in patients with type 1 diabetes and proteinuria. Diabetes Care 2014; 37: 2601-2608
    • (2014) Diabetes Care , vol.37 , pp. 2601-2608
    • Skupien, J.1    Warram, J.H.2    Niewczas, M.A.3
  • 47
    • 84857942316 scopus 로고    scopus 로고
    • Circulating TNF receptors 1 and 2 predict stage 3 CKD in type 1 diabetes
    • Gohda T, Niewczas MA, Ficociello LH et al. Circulating TNF receptors 1 and 2 predict stage 3 CKD in type 1 diabetes. J Am Soc Nephrol 2012; 23: 516-524
    • (2012) J Am Soc Nephrol , vol.23 , pp. 516-524
    • Gohda, T.1    Niewczas, M.A.2    Ficociello, L.H.3
  • 48
    • 79951889923 scopus 로고    scopus 로고
    • FGF-23 as a predictor of renal outcome in diabetic nephropathy
    • Titan SM, Zatz R, Graciolli FG et al. FGF-23 as a predictor of renal outcome in diabetic nephropathy. Clin J Am Soc Nephrol 2011; 6: 241-247
    • (2011) Clin J Am Soc Nephrol , vol.6 , pp. 241-247
    • Titan, S.M.1    Zatz, R.2    Graciolli, F.G.3
  • 49
    • 84868090154 scopus 로고    scopus 로고
    • Low HDL cholesterol and the risk of diabetic nephropathy and retinopathy: Results of the ADVANCE study
    • Morton J, Zoungas S, Li Q et al. Low HDL cholesterol and the risk of diabetic nephropathy and retinopathy: results of the ADVANCE study. Diabetes Care 2012; 35: 2201-2206
    • (2012) Diabetes Care , vol.35 , pp. 2201-2206
    • Morton, J.1    Zoungas, S.2    Li, Q.3
  • 50
    • 84928701395 scopus 로고    scopus 로고
    • A prospective study of multiple protein biomarkers to predict progression in diabetic chronic kidney disease
    • Agarwal R, Duffin KL, Laska DA et al. A prospective study of multiple protein biomarkers to predict progression in diabetic chronic kidney disease. Nephrol Dial Transplant 2014; 29: 2293-2302
    • (2014) Nephrol Dial Transplant , vol.29 , pp. 2293-2302
    • Agarwal, R.1    Duffin, K.L.2    Laska, D.A.3
  • 51
    • 56749162146 scopus 로고    scopus 로고
    • Endothelial dysfunction and inflammation predict development of diabetic nephropathy in the Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria (IRMA 2) study
    • Persson F, Rossing P, Hovind P et al. Endothelial dysfunction and inflammation predict development of diabetic nephropathy in the Irbesartan in Patients with Type 2 Diabetes and Microalbuminuria (IRMA 2) study. Scand J Clin Lab Invest 2008; 68: 731-738
    • (2008) Scand J Clin Lab Invest , vol.68 , pp. 731-738
    • Persson, F.1    Rossing, P.2    Hovind, P.3
  • 52
    • 80055023975 scopus 로고    scopus 로고
    • Association between cardiac biomarkers and the development of ESRD in patients with type 2 diabetes mellitus, anemia, and CKD
    • Desai AS, Toto R, Jarolim P et al. Association between cardiac biomarkers and the development of ESRD in patients with type 2 diabetes mellitus, anemia, and CKD. Am J Kidney Dis 2011; 58: 717-728
    • (2011) Am J Kidney Dis , vol.58 , pp. 717-728
    • Desai, A.S.1    Toto, R.2    Jarolim, P.3
  • 53
    • 84873405796 scopus 로고    scopus 로고
    • Circulating bone morphogenetic protein-7 and transforming growth factor-beta1 are better predictors of renal end points in patients with type 2 diabetes mellitus
    • Wong MG, Perkovic V, Woodward M et al. Circulating bone morphogenetic protein-7 and transforming growth factor-beta1 are better predictors of renal end points in patients with type 2 diabetes mellitus. Kidney Int 2013; 83: 278-284
    • (2013) Kidney Int , vol.83 , pp. 278-284
    • Wong, M.G.1    Perkovic, V.2    Woodward, M.3
  • 54
    • 84885376285 scopus 로고    scopus 로고
    • Clinical value of inflammatory urinary biomarkers in overt diabetic nephropathy: A prospective study
    • Verhave JC, Bouchard J, Goupil R et al. Clinical value of inflammatory urinary biomarkers in overt diabetic nephropathy: a prospective study. Diabetes Res Clin Pract 2013; 101: 333-340
    • (2013) Diabetes Res Clin Pract , vol.101 , pp. 333-340
    • Verhave, J.C.1    Bouchard, J.2    Goupil, R.3
  • 55
    • 84929340259 scopus 로고    scopus 로고
    • A panel of novel biomarkers representing different disease pathways improves prediction of renal function decline in type 2 diabetes
    • Pena MJ, Heinzel A, Heinze G et al. A panel of novel biomarkers representing different disease pathways improves prediction of renal function decline in type 2 diabetes. PLoS One 2015; 10: e0120995
    • (2015) PLoS One , vol.10
    • Pena, M.J.1    Heinzel, A.2    Heinze, G.3
  • 56
    • 84939619450 scopus 로고    scopus 로고
    • Will the future lie in multitude? A critical appraisal of biomarker panel studies on prediction of diabetic kidney disease progression
    • Suppl 4
    • Schutte E, Gansevoort RT, Benner J et al. Will the future lie in multitude? A critical appraisal of biomarker panel studies on prediction of diabetic kidney disease progression. Nephrol Dial Transplant 2015; 30 (Suppl 4): iv96-iv104
    • (2015) Nephrol Dial Transplant , vol.30 , pp. iv96-iv104
    • Schutte, E.1    Gansevoort, R.T.2    Benner, J.3
  • 57
    • 84866136320 scopus 로고    scopus 로고
    • Perspectives on systems biology applications in diabetic kidney disease
    • Komorowsky CV, Brosius FC, III, Pennathur S et al. Perspectives on systems biology applications in diabetic kidney disease. J Cardiovasc Transl Res 2012; 5: 491-508
    • (2012) J Cardiovasc Transl Res , vol.5 , pp. 491-508
    • Komorowsky, C.V.1    Brosius, F.C.2    Pennathur, S.3
  • 58
    • 39749142228 scopus 로고    scopus 로고
    • The search for new cardiovascular biomarkers
    • Gerszten RE, Wang TJ. The search for new cardiovascular biomarkers. Nature 2008; 451: 949-952
    • (2008) Nature , vol.451 , pp. 949-952
    • Gerszten, R.E.1    Wang, T.J.2
  • 59
    • 69849113129 scopus 로고    scopus 로고
    • Urinary peptidome may predict renal function decline in type 1 diabetes and microalbuminuria
    • Merchant ML, Perkins BA, Boratyn GM et al. Urinary peptidome may predict renal function decline in type 1 diabetes and microalbuminuria. J Am Soc Nephrol 2009; 20: 2065-2074
    • (2009) J Am Soc Nephrol , vol.20 , pp. 2065-2074
    • Merchant, M.L.1    Perkins, B.A.2    Boratyn, G.M.3
  • 60
    • 77956241177 scopus 로고    scopus 로고
    • Proteomic approaches for discovering biomarkers of diabetic nephropathy
    • Ben Ameur R, Molina L, Bolvin C et al. Proteomic approaches for discovering biomarkers of diabetic nephropathy. Nephrol Dial Transplant 2010; 25: 2866-2875
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 2866-2875
    • Ben Ameur, R.1    Molina, L.2    Bolvin, C.3
  • 61
    • 33847635745 scopus 로고    scopus 로고
    • Prediction of diabetic nephropathy using urine proteomic profiling 10 years prior to development of nephropathy
    • Otu HH, Can H, Spentzos D et al. Prediction of diabetic nephropathy using urine proteomic profiling 10 years prior to development of nephropathy. Diabetes Care 2007; 30: 638-643
    • (2007) Diabetes Care , vol.30 , pp. 638-643
    • Otu, H.H.1    Can, H.2    Spentzos, D.3
  • 62
    • 84882259917 scopus 로고    scopus 로고
    • Urine haptoglobin levels predict early renal functional decline in patients with type 2 diabetes
    • Bhensdadia NM, Hunt KJ, Lopes-Virella MF et al. Urine haptoglobin levels predict early renal functional decline in patients with type 2 diabetes. Kidney Int 2013; 83: 1136-1143
    • (2013) Kidney Int , vol.83 , pp. 1136-1143
    • Bhensdadia, N.M.1    Hunt, K.J.2    Lopes-Virella, M.F.3
  • 63
    • 84870328390 scopus 로고    scopus 로고
    • Urinary proteomics for early diagnosis in diabetic nephropathy
    • Zurbig P, Jerums G, Hovind P et al. Urinary proteomics for early diagnosis in diabetic nephropathy. Diabetes 2012; 61: 3304-3313
    • (2012) Diabetes , vol.61 , pp. 3304-3313
    • Zurbig, P.1    Jerums, G.2    Hovind, P.3
  • 64
    • 84939646955 scopus 로고    scopus 로고
    • Plasma proteomics classifiers improve risk prediction for renal disease in patients with hypertension or type 2 diabetes
    • Accepted
    • Pena M, Jankowski J, Heinze G et al. Plasma proteomics classifiers improve risk prediction for renal disease in patients with hypertension or type 2 diabetes. J Hypertens 2015; [Accepted]
    • (2015) J Hypertens
    • Pena, M.1    Jankowski, J.2    Heinze, G.3
  • 65
    • 84906224684 scopus 로고    scopus 로고
    • Urine and plasma metabolites predict the development of diabetic nephropathy in individuals with Type 2 diabetes mellitus
    • Pena MJ, Lambers Heerspink HJ, Hellemons ME et al. Urine and plasma metabolites predict the development of diabetic nephropathy in individuals with Type 2 diabetes mellitus. Diabet Med 2014; 31: 1138-1147
    • (2014) Diabet Med , vol.31 , pp. 1138-1147
    • Pena, M.J.1    Lambers Heerspink, H.J.2    Hellemons, M.E.3
  • 66
    • 78049419330 scopus 로고    scopus 로고
    • Urinary proteomics based on capillary electrophoresis-coupled mass spectrometry in kidney disease: Discovery and validation of biomarkers, and clinical application
    • Mischak H, Delles C, Klein J et al. Urinary proteomics based on capillary electrophoresis-coupled mass spectrometry in kidney disease: discovery and validation of biomarkers, and clinical application. Adv Chronic Kidney Dis 2010; 17: 493-506
    • (2010) Adv Chronic Kidney Dis , vol.17 , pp. 493-506
    • Mischak, H.1    Delles, C.2    Klein, J.3
  • 67
    • 78149291420 scopus 로고    scopus 로고
    • Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease
    • Good DM, Zurbig P, Argiles A et al. Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease. Mol Cell Proteomics 2010; 9: 2424-2437
    • (2010) Mol Cell Proteomics , vol.9 , pp. 2424-2437
    • Good, D.M.1    Zurbig, P.2    Argiles, A.3
  • 68
    • 84875597573 scopus 로고    scopus 로고
    • A urinary peptide biomarker set predicts worsening of albuminuria in type 2 diabetes mellitus
    • Roscioni SS, de Zeeuw D, Hellemons ME et al. A urinary peptide biomarker set predicts worsening of albuminuria in type 2 diabetes mellitus. Diabetologia 2013; 56: 259-267
    • (2013) Diabetologia , vol.56 , pp. 259-267
    • Roscioni, S.S.1    De Zeeuw, D.2    Hellemons, M.E.3
  • 69
    • 84926612422 scopus 로고    scopus 로고
    • Diagnosis and prediction of CKD progression by assessment of urinary peptides
    • Schanstra JP, Zürbig P, Alkhalaf A et al. Diagnosis and prediction of CKD progression by assessment of urinary peptides. J Am Soc Nephrol 2015; doi: 10.1681/ASN.2014050423
    • (2015) J Am Soc Nephrol
    • Schanstra, J.P.1    Zürbig, P.2    Alkhalaf, A.3
  • 70
    • 48149087279 scopus 로고    scopus 로고
    • Urinary proteomics in diabetes and CKD
    • Rossing K, Mischak H, Dakna M et al. Urinary proteomics in diabetes and CKD. J Am Soc Nephrol 2008; 19: 1283-1290
    • (2008) J Am Soc Nephrol , vol.19 , pp. 1283-1290
    • Rossing, K.1    Mischak, H.2    Dakna, M.3
  • 71
    • 18844370547 scopus 로고    scopus 로고
    • Capillary electrophoresis-mass spectrometry as a powerful tool in clinical diagnosis and biomarker discovery
    • Kolch W, Neususs C, Pelzing M et al. Capillary electrophoresis-mass spectrometry as a powerful tool in clinical diagnosis and biomarker discovery. Mass Spectrom Rev 2005; 24: 959-977
    • (2005) Mass Spectrom Rev , vol.24 , pp. 959-977
    • Kolch, W.1    Neususs, C.2    Pelzing, M.3
  • 72
    • 34548191121 scopus 로고    scopus 로고
    • The discovery of biomarkers for type 2 diabetic nephropathy by serum proteome analysis
    • Cho EH, Kim MR, Kim HJ et al. The discovery of biomarkers for type 2 diabetic nephropathy by serum proteome analysis. Proteomics Clin Appl 2007; 1: 352-361
    • (2007) Proteomics Clin Appl , vol.1 , pp. 352-361
    • Cho, E.H.1    Kim, M.R.2    Kim, H.J.3
  • 73
    • 33847395363 scopus 로고    scopus 로고
    • Proteome analysis of serum from type 2 diabetics with nephropathy
    • Kim HJ, Cho EH, Yoo JH et al. Proteome analysis of serum from type 2 diabetics with nephropathy. J Proteome Res 2007; 6: 735-743
    • (2007) J Proteome Res , vol.6 , pp. 735-743
    • Kim, H.J.1    Cho, E.H.2    Yoo, J.H.3
  • 74
    • 69249127046 scopus 로고    scopus 로고
    • Metabonomics research of diabetic nephropathy and type 2 diabetes mellitus based on UPLC-oaTOF-MS system
    • Zhang J, Yan L, Chen W et al. Metabonomics research of diabetic nephropathy and type 2 diabetes mellitus based on UPLC-oaTOF-MS system. Anal Chim Acta 2009; 650: 16-22
    • (2009) Anal Chim Acta , vol.650 , pp. 16-22
    • Zhang, J.1    Yan, L.2    Chen, W.3
  • 75
    • 79951725634 scopus 로고    scopus 로고
    • Plasma esterified and non-esterified fatty acids metabolic profiling using gas chromatography-mass spectrometry and its application in the study of diabetic mellitus and diabetic nephropathy
    • Han LD, Xia JF, Liang QL et al. Plasma esterified and non-esterified fatty acids metabolic profiling using gas chromatography-mass spectrometry and its application in the study of diabetic mellitus and diabetic nephropathy. Anal Chim Acta 2011; 689: 85-91
    • (2011) Anal Chim Acta , vol.689 , pp. 85-91
    • Han, L.D.1    Xia, J.F.2    Liang, Q.L.3
  • 76
    • 84870947792 scopus 로고    scopus 로고
    • Metabolic profiling reveals new serum biomarkers for differentiating diabetic nephropathy
    • Hirayama A, Nakashima E, Sugimoto M et al. Metabolic profiling reveals new serum biomarkers for differentiating diabetic nephropathy. Anal Bioanal Chem 2012; 404: 3101-3109
    • (2012) Anal Bioanal Chem , vol.404 , pp. 3101-3109
    • Hirayama, A.1    Nakashima, E.2    Sugimoto, M.3
  • 77
    • 84887108045 scopus 로고    scopus 로고
    • Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease
    • Sharma K, Karl B, Mathew AV et al. Metabolomics reveals signature of mitochondrial dysfunction in diabetic kidney disease. J Am Soc Nephrol 2013; 24: 1901-1912
    • (2013) J Am Soc Nephrol , vol.24 , pp. 1901-1912
    • Sharma, K.1    Karl, B.2    Mathew, A.V.3
  • 78
    • 84899913633 scopus 로고    scopus 로고
    • Uremic solutes and risk of end-stage renal disease in type 2 diabetes: Metabolomic study
    • Niewczas MA, Sirich TL, Mathew AV et al. Uremic solutes and risk of end-stage renal disease in type 2 diabetes: metabolomic study. Kidney Int 2014; 85: 1214-1224
    • (2014) Kidney Int , vol.85 , pp. 1214-1224
    • Niewczas, M.A.1    Sirich, T.L.2    Mathew, A.V.3
  • 79
    • 80052148776 scopus 로고    scopus 로고
    • Phospholipidomic identification of potential plasma biomarkers associated with type 2 diabetes mellitus and diabetic nephropathy
    • Zhu C, Liang QL, Hu P et al. Phospholipidomic identification of potential plasma biomarkers associated with type 2 diabetes mellitus and diabetic nephropathy. Talanta 2011; 85: 1711-1720
    • (2011) Talanta , vol.85 , pp. 1711-1720
    • Zhu, C.1    Liang, Q.L.2    Hu, P.3
  • 80
    • 84856709532 scopus 로고    scopus 로고
    • A metabolomic study of low estimated GFR in non-proteinuric type 2 diabetes mellitus
    • Ng DP, Salim A, Liu Y et al. A metabolomic study of low estimated GFR in non-proteinuric type 2 diabetes mellitus. Diabetologia 2012; 55: 499-508
    • (2012) Diabetologia , vol.55 , pp. 499-508
    • Ng, D.P.1    Salim, A.2    Liu, Y.3
  • 81
    • 84855894622 scopus 로고    scopus 로고
    • Discovery of early-stage biomarkers for diabetic kidney disease using ms-based metabolomics (FinnDiane study)
    • van der Kloet FM, Tempels FWA, Ismail N et al. Discovery of early-stage biomarkers for diabetic kidney disease using ms-based metabolomics (FinnDiane study). Metabolomics 2012; 8: 109-119
    • (2012) Metabolomics , vol.8 , pp. 109-119
    • Van Der Kloet, F.M.1    Tempels, F.W.A.2    Ismail, N.3
  • 82
    • 20144363431 scopus 로고    scopus 로고
    • Proteinuria reduction and progression to renal failure in patients with type 2 diabetes mellitus and overt nephropathy
    • Atkins RC, Briganti EM, Lewis JB et al. Proteinuria reduction and progression to renal failure in patients with type 2 diabetes mellitus and overt nephropathy. Am J Kidney Dis 2005; 45: 281-287
    • (2005) Am J Kidney Dis , vol.45 , pp. 281-287
    • Atkins, R.C.1    Briganti, E.M.2    Lewis, J.B.3
  • 83
    • 84855987525 scopus 로고    scopus 로고
    • Initial angiotensin receptor blockade-induced decrease in albuminuria is associated with long-term renal outcome in type 2 diabetic patients with microalbuminuria: A post hoc analysis of the IRMA-2 trial
    • Hellemons ME, Persson F, Bakker SJ et al. Initial angiotensin receptor blockade-induced decrease in albuminuria is associated with long-term renal outcome in type 2 diabetic patients with microalbuminuria: a post hoc analysis of the IRMA-2 trial. Diabetes Care 2011; 34: 2078-2083
    • (2011) Diabetes Care , vol.34 , pp. 2078-2083
    • Hellemons, M.E.1    Persson, F.2    Bakker, S.J.3
  • 84
    • 20244382844 scopus 로고    scopus 로고
    • The relationship between magnitude of proteinuria reduction and risk of end-stage renal disease: Results of the African American study of kidney disease and hypertension
    • Lea J, Greene T, Hebert L et al. The relationship between magnitude of proteinuria reduction and risk of end-stage renal disease: results of the African American study of kidney disease and hypertension. Arch Intern Med 2005; 165: 947-953
    • (2005) Arch Intern Med , vol.165 , pp. 947-953
    • Lea, J.1    Greene, T.2    Hebert, L.3
  • 85
    • 0038188560 scopus 로고    scopus 로고
    • Retarding progression of chronic renal disease: The neglected issue of residual proteinuria
    • Ruggenenti P, Perna A, Remuzzi G et al. Retarding progression of chronic renal disease: the neglected issue of residual proteinuria. Kidney Int 2003; 63: 2254-2261
    • (2003) Kidney Int , vol.63 , pp. 2254-2261
    • Ruggenenti, P.1    Perna, A.2    Remuzzi, G.3
  • 86
    • 84924173941 scopus 로고    scopus 로고
    • Effect of pentoxifylline on renal function and urinary albumin excretion in patients with diabetic kidney disease: The PREDIAN Trial
    • Navarro-Gonzalez JF, Mora-Fernandez C, Muros de Fuentes M et al. Effect of pentoxifylline on renal function and urinary albumin excretion in patients with diabetic kidney disease: the PREDIAN Trial. J Am Soc Nephrol 2015; 26: 220-229
    • (2015) J Am Soc Nephrol , vol.26 , pp. 220-229
    • Navarro-Gonzalez, J.F.1    Mora-Fernandez, C.2    Muros De Fuentes, M.3
  • 87
    • 84855245399 scopus 로고    scopus 로고
    • Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes
    • DCCT/EDIC Research Groupde Boer IH, Sun W et al. Intensive diabetes therapy and glomerular filtration rate in type 1 diabetes. N Engl J Med 2011; 365: 2366-2376
    • (2011) N Engl J Med , vol.365 , pp. 2366-2376
    • Boer, I.H.1    Sun, W.2
  • 88
    • 0028215329 scopus 로고
    • The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease
    • Modification of Diet in Renal Disease Study Group
    • Klahr S, Levey AS, Beck GJ et al. The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. Modification of Diet in Renal Disease Study Group. N Engl J Med 1994; 330: 877-884
    • (1994) N Engl J Med , vol.330 , pp. 877-884
    • Klahr, S.1    Levey, A.S.2    Beck, G.J.3
  • 89
    • 39349106306 scopus 로고    scopus 로고
    • The effect of losartan on hemoglobin concentration and renal outcome in diabetic nephropathy of type 2 diabetes
    • Mohanram A, Zhang Z, Shahinfar S et al. The effect of losartan on hemoglobin concentration and renal outcome in diabetic nephropathy of type 2 diabetes. Kidney Int 2008; 73: 630-636
    • (2008) Kidney Int , vol.73 , pp. 630-636
    • Mohanram, A.1    Zhang, Z.2    Shahinfar, S.3
  • 90
    • 0021948044 scopus 로고
    • Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass
    • Anderson S, Meyer TW, Rennke HG et al. Control of glomerular hypertension limits glomerular injury in rats with reduced renal mass. J Clin Invest 1985; 76: 612-619
    • (1985) J Clin Invest , vol.76 , pp. 612-619
    • Anderson, S.1    Meyer, T.W.2    Rennke, H.G.3
  • 91
    • 0030887031 scopus 로고    scopus 로고
    • A short-term antihypertensive treatment-induced fall in glomerular filtration rate predicts long-term stability of renal function
    • Apperloo AJ, de Zeeuw D, de Jong PE. A short-term antihypertensive treatment-induced fall in glomerular filtration rate predicts long-term stability of renal function. Kidney Int 1997; 51: 793-797
    • (1997) Kidney Int , vol.51 , pp. 793-797
    • Apperloo, A.J.1    De Zeeuw, D.2    De Jong, P.E.3
  • 92
    • 0031473535 scopus 로고    scopus 로고
    • Kidney function after withdrawal of long-term antihypertensive treatment in diabetic nephropathy
    • Hansen HP, Nielsen FS, Rossing P et al. Kidney function after withdrawal of long-term antihypertensive treatment in diabetic nephropathy. Kidney Int Suppl 1997; 63: S49-S53
    • (1997) Kidney Int Suppl , vol.63 , pp. S49-S53
    • Hansen, H.P.1    Nielsen, F.S.2    Rossing, P.3
  • 93
    • 79960407033 scopus 로고    scopus 로고
    • An acute fall in estimated glomerular filtration rate during treatment with losartan predicts a slower decrease in long-term renal function
    • Holtkamp FA, de Zeeuw D, Thomas MC et al. An acute fall in estimated glomerular filtration rate during treatment with losartan predicts a slower decrease in long-term renal function. Kidney Int 2011; 80: 282-287
    • (2011) Kidney Int , vol.80 , pp. 282-287
    • Holtkamp, F.A.1    De Zeeuw, D.2    Thomas, M.C.3
  • 94
    • 84896465696 scopus 로고    scopus 로고
    • A prediction of the renal and cardiovascular efficacy of aliskiren in ALTITUDE using short-term changes in multiple risk markers
    • Smink PA, Hoekman J, Grobbee DE et al. A prediction of the renal and cardiovascular efficacy of aliskiren in ALTITUDE using short-term changes in multiple risk markers. Eur J Prev Cardiol 2014; 21: 434-441
    • (2014) Eur J Prev Cardiol , vol.21 , pp. 434-441
    • Smink, P.A.1    Hoekman, J.2    Grobbee, D.E.3
  • 95
    • 84893805586 scopus 로고    scopus 로고
    • The importance of short-term off-target effects in estimating the long-term renal and cardiovascular protection of angiotensin receptor blockers
    • Smink PA, Miao Y, Eijkemans MJ et al. The importance of short-term off-target effects in estimating the long-term renal and cardiovascular protection of angiotensin receptor blockers. Clin Pharmacol Ther 2014; 95: 208-215
    • (2014) Clin Pharmacol Ther , vol.95 , pp. 208-215
    • Smink, P.A.1    Miao, Y.2    Eijkemans, M.J.3
  • 96
    • 84927176250 scopus 로고    scopus 로고
    • A novel approach for establishing cardiovascular drug efficacy
    • Heerspink HJ, Grobbee DE, de Zeeuw D. A novel approach for establishing cardiovascular drug efficacy. Nat Rev Drug Discov 2014; 13: 942.
    • (2014) Nat Rev Drug Discov , vol.13 , pp. 942
    • Heerspink, H.J.1    Grobbee, D.E.2    De Zeeuw, D.3
  • 97
    • 84878082474 scopus 로고    scopus 로고
    • Levels of NT-proBNP, markers of low-grade inflammation, and endothelial dysfunction during spironolactone treatment in patients with diabetic kidney disease
    • Nielsen SE, Schjoedt KJ, Rossing K et al. Levels of NT-proBNP, markers of low-grade inflammation, and endothelial dysfunction during spironolactone treatment in patients with diabetic kidney disease. J Renin Angiotensin Aldosterone Syst 2013; 14: 161-166
    • (2013) J Renin Angiotensin Aldosterone Syst , vol.14 , pp. 161-166
    • Nielsen, S.E.1    Schjoedt, K.J.2    Rossing, K.3
  • 98
    • 24944524156 scopus 로고    scopus 로고
    • Impact of diabetic nephropathy and angiotensin II receptor blockade on urinary polypeptide patterns
    • Rossing K, Mischak H, Parving HH et al. Impact of diabetic nephropathy and angiotensin II receptor blockade on urinary polypeptide patterns. Kidney Int 2005; 68: 193-205
    • (2005) Kidney Int , vol.68 , pp. 193-205
    • Rossing, K.1    Mischak, H.2    Parving, H.H.3
  • 99
    • 77958612605 scopus 로고    scopus 로고
    • Urinary proteome analysis enables assessment of renoprotective treatment in type 2 diabetic patients with microalbuminuria
    • Andersen S, Mischak H, Zurbig P et al. Urinary proteome analysis enables assessment of renoprotective treatment in type 2 diabetic patients with microalbuminuria. BMC Nephrol 2010; 11: 29
    • (2010) BMC Nephrol , vol.11 , pp. 29
    • Andersen, S.1    Mischak, H.2    Zurbig, P.3
  • 100
    • 84939645959 scopus 로고    scopus 로고
    • Urine metabolomic profile correlates with renal function and changes during atrasentan therapy in patients with diabetes and nephropathy
    • [abstract]
    • Lambers Heerspink HJ, de Zeeuw D, Sharma S et al. Urine metabolomic profile correlates with renal function and changes during atrasentan therapy in patients with diabetes and nephropathy [abstract]. J Am Soc Nephrol 2014; 25: 546A
    • (2014) J Am Soc Nephrol , vol.25 , pp. 546A
    • Lambers Heerspink, H.J.1    De Zeeuw, D.2    Sharma, S.3


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