Rat, mouse, and primate models of chronic glaucoma show sustained elevation of extracellular ATP and altered purinergic signaling in the posterior eye

Investigative Ophthalmology and Visual Science

Volumn 56, Issue 5, 2015, Pages 3075-3083

  Lu, Wennan ^a   Hu, Huiling ^a,b   Sévigny, Jean ^c   Gabelt, B’ann T ^d   Kaufman, Paul L ^d   Johnson, Elaine C ^e   Morrison, John C ^e   Zode, Gulab S ^f,g   Sheffield, Val C ^f   Zhang, Xiulan ^b   Laties, Alan M ^a   Mitchell, Claire H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c LAVAL UNIVERSITY   (Canada)

^d UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^f UNIVERSITY OF IOWA   (United States)

^g UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

Author keywords

ATP release; Mechanosensitive; Retina

Indexed keywords

ADENOSINE TRIPHOSPHATE; NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1; PHOSPHATASE; UNCLASSIFIED DRUG; APYRASE; CD39 ANTIGEN; LEUKOCYTE ANTIGEN;

ADULT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; GLAUCOMA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INTRAOCULAR PRESSURE; LUCIFERASE ASSAY; MALE; MOUSE; NONHUMAN; OPTIC NERVE; POLYMERASE CHAIN REACTION; PRIMATE MODEL; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; VITREOUS BODY; ANIMAL; BROWN NORWAY RAT; C57BL MOUSE; CHRONIC DISEASE; DISEASE MODEL; FEMALE; GENETICS; MACACA FASCICULARIS; METABOLISM; PATHOLOGY; PHYSIOLOGY; POSTERIOR EYE SEGMENT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ADENOSINE TRIPHOSPHATE; ANIMALS; ANTIGENS, CD; APYRASE; CELL COUNT; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; FEMALE; GLAUCOMA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; INTRAOCULAR PRESSURE; MACACA FASCICULARIS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; POSTERIOR EYE SEGMENT; RATS; RATS, INBRED BN; REAL-TIME POLYMERASE CHAIN REACTION; RETINAL GANGLION CELLS; SIGNAL TRANSDUCTION;

EID: 84939620961     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.14-15891     Document Type: Article

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