메뉴 건너뛰기




Volumn 337, Issue 1, 2015, Pages 1-15

Hyaluronan synthase 3 (HAS3) overexpression downregulates MV3 melanoma cell proliferation, migration and adhesion

Author keywords

Adhesion; Cell cycle; ERK1 2; HAS3; Hyaluronan; Melanoma; Migration; Proliferation

Indexed keywords

DOXYCYCLINE; HYALURONAN SYNTHASE 3; HYALURONIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OLIGOSACCHARIDE; RECOMBINANT ENZYME; STREPTOMYCES HYALURONIDASE; SYNTHETASE; UNCLASSIFIED DRUG; ENHANCED GREEN FLUORESCENT PROTEIN; GLUCURONOSYLTRANSFERASE; GREEN FLUORESCENT PROTEIN; HAS3 PROTEIN, HUMAN; HYBRID PROTEIN;

EID: 84939572837     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2015.07.026     Document Type: Article
Times cited : (21)

References (99)
  • 2
    • 0030001849 scopus 로고    scopus 로고
    • Expression cloning and molecular characterization of HAS protein, a eukaryotic hyaluronan synthase
    • Itano N., Kimata K. Expression cloning and molecular characterization of HAS protein, a eukaryotic hyaluronan synthase. J. Biol. Chem. 1996, 271:9875-9878.
    • (1996) J. Biol. Chem. , vol.271 , pp. 9875-9878
    • Itano, N.1    Kimata, K.2
  • 4
    • 0031939945 scopus 로고    scopus 로고
    • Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family
    • Spicer A.P., McDonald J.A. Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family. J. Biol. Chem. 1998, 273:1923-1932.
    • (1998) J. Biol. Chem. , vol.273 , pp. 1923-1932
    • Spicer, A.P.1    McDonald, J.A.2
  • 5
    • 17444388568 scopus 로고    scopus 로고
    • Three vertebrate hyaluronan synthases are expressed during mouse development in distinct spatial and temporal patterns
    • Tien J.Y., Spicer A.P. Three vertebrate hyaluronan synthases are expressed during mouse development in distinct spatial and temporal patterns. Dev. Dyn. 2005, 233:130-141.
    • (2005) Dev. Dyn. , vol.233 , pp. 130-141
    • Tien, J.Y.1    Spicer, A.P.2
  • 9
    • 0025966878 scopus 로고
    • Hyaluronan and a cell-associated hyaluronan binding protein regulate the locomotion of ras-transformed cells
    • Turley E.A., Austen L., Vandeligt K., Clary C. Hyaluronan and a cell-associated hyaluronan binding protein regulate the locomotion of ras-transformed cells. J. Cell Biol. 1991, 112:1041-1047.
    • (1991) J. Cell Biol. , vol.112 , pp. 1041-1047
    • Turley, E.A.1    Austen, L.2    Vandeligt, K.3    Clary, C.4
  • 10
    • 0016221606 scopus 로고
    • Aggregation of cartilage proteoglycans. II. Oligosaccharide competitors of the proteoglycan-hyaluronic acid interaction
    • Hascall V.C., Heinegard D. Aggregation of cartilage proteoglycans. II. Oligosaccharide competitors of the proteoglycan-hyaluronic acid interaction. J. Biol. Chem. 1974, 249:4242-4249.
    • (1974) J. Biol. Chem. , vol.249 , pp. 4242-4249
    • Hascall, V.C.1    Heinegard, D.2
  • 11
    • 0016211754 scopus 로고
    • Aggregation of cartilage proteoglycans. I. The role of hyaluronic acid
    • Hascall V.C., Heinegard D. Aggregation of cartilage proteoglycans. I. The role of hyaluronic acid. J. Biol. Chem. 1974, 249:4232-4241.
    • (1974) J. Biol. Chem. , vol.249 , pp. 4232-4241
    • Hascall, V.C.1    Heinegard, D.2
  • 12
    • 0023851740 scopus 로고
    • Localization of epidermal hyaluronic acid using the hyaluronate binding region of cartilage proteoglycan as a specific probe
    • Tammi R., Ripellino J.A., Margolis R.U., Tammi M. Localization of epidermal hyaluronic acid using the hyaluronate binding region of cartilage proteoglycan as a specific probe. J. Invest. Dermatol. 1988, 90:412-414.
    • (1988) J. Invest. Dermatol. , vol.90 , pp. 412-414
    • Tammi, R.1    Ripellino, J.A.2    Margolis, R.U.3    Tammi, M.4
  • 14
    • 0015510675 scopus 로고
    • The specific interaction of hyaluronic acid with cartillage proteoglycans
    • Hardingham T.E., Muir H. The specific interaction of hyaluronic acid with cartillage proteoglycans. Biochim. Biophys. Acta 1972, 279:401-405.
    • (1972) Biochim. Biophys. Acta , vol.279 , pp. 401-405
    • Hardingham, T.E.1    Muir, H.2
  • 16
    • 44749083057 scopus 로고    scopus 로고
    • Hyaluronan in human tumors: pathobiological and prognostic messages from cell-associated and stromal hyaluronan
    • Tammi R.H., Kultti A., Kosma V.M., Pirinen R., Auvinen P., Tammi M.I. Hyaluronan in human tumors: pathobiological and prognostic messages from cell-associated and stromal hyaluronan. Semin. Cancer Biol. 2008, 18:288-295.
    • (2008) Semin. Cancer Biol. , vol.18 , pp. 288-295
    • Tammi, R.H.1    Kultti, A.2    Kosma, V.M.3    Pirinen, R.4    Auvinen, P.5    Tammi, M.I.6
  • 18
    • 84875828646 scopus 로고    scopus 로고
    • Inverse expression of hyaluronidase 2 and hyaluronan synthases 1-3 is associated with reduced hyaluronan content in malignant cutaneous melanoma
    • 181-2407-13-181
    • Siiskonen H., Poukka M., Tyynelä-Korhonen K., Sironen R., Pasonen-Seppänen S. Inverse expression of hyaluronidase 2 and hyaluronan synthases 1-3 is associated with reduced hyaluronan content in malignant cutaneous melanoma. BMC Cancer 2013, 13. 181-2407-13-181.
    • (2013) BMC Cancer , vol.13
    • Siiskonen, H.1    Poukka, M.2    Tyynelä-Korhonen, K.3    Sironen, R.4    Pasonen-Seppänen, S.5
  • 19
    • 0035393499 scopus 로고    scopus 로고
    • Hyaluronan synthase 3 overexpression promotes the growth of TSU prostate cancer cells
    • Liu N., Gao F., Han Z., Xu X., Underhill C.B., Zhang L. Hyaluronan synthase 3 overexpression promotes the growth of TSU prostate cancer cells. Cancer Res. 2001, 61:5207-5214.
    • (2001) Cancer Res. , vol.61 , pp. 5207-5214
    • Liu, N.1    Gao, F.2    Han, Z.3    Xu, X.4    Underhill, C.B.5    Zhang, L.6
  • 21
    • 0038129491 scopus 로고    scopus 로고
    • EGF upregulates, whereas TGF-beta downregulates, the hyaluronan synthases Has2 and Has3 in organotypic keratinocyte cultures: correlations with epidermal proliferation and differentiation
    • Pasonen-Seppänen S., Karvinen S., Törrönen K., Hyttinen J.M., Jokela T., Lammi M.J., Tammi M.I., Tammi R. EGF upregulates, whereas TGF-beta downregulates, the hyaluronan synthases Has2 and Has3 in organotypic keratinocyte cultures: correlations with epidermal proliferation and differentiation. J. Invest. Dermatol. 2003, 120:1038-1044.
    • (2003) J. Invest. Dermatol. , vol.120 , pp. 1038-1044
    • Pasonen-Seppänen, S.1    Karvinen, S.2    Törrönen, K.3    Hyttinen, J.M.4    Jokela, T.5    Lammi, M.J.6    Tammi, M.I.7    Tammi, R.8
  • 22
    • 84872187435 scopus 로고    scopus 로고
    • Melanoma cell-derived factors stimulate hyaluronan synthesis in dermal fibroblasts by upregulating HAS2 through PDGFR-PI3K-AKT and p38 signaling
    • Pasonen-Seppänen S., Takabe P., Edward M., Rauhala L., Rilla K., Tammi M., Tammi R. Melanoma cell-derived factors stimulate hyaluronan synthesis in dermal fibroblasts by upregulating HAS2 through PDGFR-PI3K-AKT and p38 signaling. Histochem. Cell Biol. 2012, 138:895-911.
    • (2012) Histochem. Cell Biol. , vol.138 , pp. 895-911
    • Pasonen-Seppänen, S.1    Takabe, P.2    Edward, M.3    Rauhala, L.4    Rilla, K.5    Tammi, M.6    Tammi, R.7
  • 24
    • 84892805020 scopus 로고    scopus 로고
    • Inhibition of hyaluronan synthase 2 reduces the abnormal migration rate of keloid keratinocytes
    • Supp D.M., Hahn J.M., McFarland K.L., Glaser K. Inhibition of hyaluronan synthase 2 reduces the abnormal migration rate of keloid keratinocytes. J. Burn Care Res. 2014, 35:84-92.
    • (2014) J. Burn Care Res. , vol.35 , pp. 84-92
    • Supp, D.M.1    Hahn, J.M.2    McFarland, K.L.3    Glaser, K.4
  • 25
    • 84884208384 scopus 로고    scopus 로고
    • Efficient TGFbeta-induced epithelial-mesenchymal transition depends on hyaluronan synthase HAS2
    • Porsch H., Bernert B., Mehic M., Theocharis A.D., Heldin C.H., Heldin P. Efficient TGFbeta-induced epithelial-mesenchymal transition depends on hyaluronan synthase HAS2. Oncogene 2013, 32:4355-4365.
    • (2013) Oncogene , vol.32 , pp. 4355-4365
    • Porsch, H.1    Bernert, B.2    Mehic, M.3    Theocharis, A.D.4    Heldin, C.H.5    Heldin, P.6
  • 26
    • 0033230844 scopus 로고    scopus 로고
    • Expression of recombinant hyaluronan synthase (HAS) isoforms in CHO cells reduces cell migration and cell surface CD44
    • Brinck J., Heldin P. Expression of recombinant hyaluronan synthase (HAS) isoforms in CHO cells reduces cell migration and cell surface CD44. Exp. Cell Res. 1999, 252:342-351.
    • (1999) Exp. Cell Res. , vol.252 , pp. 342-351
    • Brinck, J.1    Heldin, P.2
  • 27
    • 0036626690 scopus 로고    scopus 로고
    • Overexpression of hyaluronan synthase-2 reduces the tumorigenic potential of glioma cells lacking hyaluronidase activity
    • Enegd B., King J.A., Stylli S., Paradiso L., Kaye A.H., Novak U. Overexpression of hyaluronan synthase-2 reduces the tumorigenic potential of glioma cells lacking hyaluronidase activity. Neurosurgery 2002, 50:1311-1318.
    • (2002) Neurosurgery , vol.50 , pp. 1311-1318
    • Enegd, B.1    King, J.A.2    Stylli, S.3    Paradiso, L.4    Kaye, A.H.5    Novak, U.6
  • 28
    • 0024367374 scopus 로고
    • Hyaluronan and angiogenesis
    • discussion 201-7, 281-5
    • West D.C., Kumar S. Hyaluronan and angiogenesis. Ciba Found. Symp. 1989, 143:187-201. discussion 201-7, 281-5.
    • (1989) Ciba Found. Symp. , vol.143 , pp. 187-201
    • West, D.C.1    Kumar, S.2
  • 29
  • 30
    • 76549091233 scopus 로고    scopus 로고
    • Hyaluronan oligosaccharides promote excisional wound healing through enhanced angiogenesis
    • Gao F., Liu Y., He Y., Yang C., Wang Y., Shi X., Wei G. Hyaluronan oligosaccharides promote excisional wound healing through enhanced angiogenesis. Matrix Biol. 2010, 29:107-116.
    • (2010) Matrix Biol. , vol.29 , pp. 107-116
    • Gao, F.1    Liu, Y.2    He, Y.3    Yang, C.4    Wang, Y.5    Shi, X.6    Wei, G.7
  • 32
    • 57649131056 scopus 로고    scopus 로고
    • Differential activation of ERK and rac mediates the proliferative and anti-proliferative effects of hyaluronan and CD44
    • Kothapalli D., Flowers J., Xu T., Pure E., Assoian R.K. Differential activation of ERK and rac mediates the proliferative and anti-proliferative effects of hyaluronan and CD44. J. Biol. Chem. 2008, 283:31823-31829.
    • (2008) J. Biol. Chem. , vol.283 , pp. 31823-31829
    • Kothapalli, D.1    Flowers, J.2    Xu, T.3    Pure, E.4    Assoian, R.K.5
  • 33
    • 77953914908 scopus 로고    scopus 로고
    • Small hyaluronan oligosaccharides induce inflammation by engaging both toll-like-4 and CD44 receptors in human chondrocytes
    • Campo G.M., Avenoso A., Campo S., D'Ascola A., Nastasi G., Calatroni A. Small hyaluronan oligosaccharides induce inflammation by engaging both toll-like-4 and CD44 receptors in human chondrocytes. Biochem. Pharmacol. 2010, 80:480-490.
    • (2010) Biochem. Pharmacol. , vol.80 , pp. 480-490
    • Campo, G.M.1    Avenoso, A.2    Campo, S.3    D'Ascola, A.4    Nastasi, G.5    Calatroni, A.6
  • 34
    • 0025802810 scopus 로고
    • Establishment and characterization of a human melanoma cell line (MV3) which is highly metastatic in nude mice
    • van Muijen G.N., Jansen K.F., Cornelissen I.M., Smeets D.F., Beck J.L., Ruiter D.J. Establishment and characterization of a human melanoma cell line (MV3) which is highly metastatic in nude mice. Int. J. Cancer 1991, 48:85-91.
    • (1991) Int. J. Cancer , vol.48 , pp. 85-91
    • van Muijen, G.N.1    Jansen, K.F.2    Cornelissen, I.M.3    Smeets, D.F.4    Beck, J.L.5    Ruiter, D.J.6
  • 39
    • 51249107345 scopus 로고    scopus 로고
    • Pericellular hyaluronan coat visualized in live cells with a fluorescent probe is scaffolded by plasma membrane protrusions
    • Rilla K., Tiihonen R., Kultti A., Tammi M., Tammi R. Pericellular hyaluronan coat visualized in live cells with a fluorescent probe is scaffolded by plasma membrane protrusions. J. Histochem. Cytochem. 2008, 56:901-910.
    • (2008) J. Histochem. Cytochem. , vol.56 , pp. 901-910
    • Rilla, K.1    Tiihonen, R.2    Kultti, A.3    Tammi, M.4    Tammi, R.5
  • 42
    • 0030297490 scopus 로고    scopus 로고
    • CD44-anchored hyaluronan-rich pericellular matrices: an ultrastructural and biochemical analysis
    • Knudson W., Aguiar D.J., Hua Q., Knudson C.B. CD44-anchored hyaluronan-rich pericellular matrices: an ultrastructural and biochemical analysis. Exp. Cell Res. 1996, 228:216-228.
    • (1996) Exp. Cell Res. , vol.228 , pp. 216-228
    • Knudson, W.1    Aguiar, D.J.2    Hua, Q.3    Knudson, C.B.4
  • 43
    • 84888205687 scopus 로고    scopus 로고
    • Hyaluronan synthase 1 (HAS1) produces a cytokine-and glucose-inducible, CD44-dependent cell surface coat
    • Siiskonen H., Kärnä R., Hyttinen J.M., Tammi R.H., Tammi M.I., Rilla K. Hyaluronan synthase 1 (HAS1) produces a cytokine-and glucose-inducible, CD44-dependent cell surface coat. Exp. Cell Res. 2014, 320:153-163.
    • (2014) Exp. Cell Res. , vol.320 , pp. 153-163
    • Siiskonen, H.1    Kärnä, R.2    Hyttinen, J.M.3    Tammi, R.H.4    Tammi, M.I.5    Rilla, K.6
  • 46
    • 33748748352 scopus 로고    scopus 로고
    • Depolymerized hyaluronan induces vascular endothelial growth factor, a negative regulator of developmental epithelial-to-mesenchymal transformation
    • Rodgers L.S., Lalani S., Hardy K.M., Xiang X., Broka D., Antin P.B., Camenisch T.D. Depolymerized hyaluronan induces vascular endothelial growth factor, a negative regulator of developmental epithelial-to-mesenchymal transformation. Circ. Res. 2006, 99:583-589.
    • (2006) Circ. Res. , vol.99 , pp. 583-589
    • Rodgers, L.S.1    Lalani, S.2    Hardy, K.M.3    Xiang, X.4    Broka, D.5    Antin, P.B.6    Camenisch, T.D.7
  • 47
    • 24744446818 scopus 로고    scopus 로고
    • Plasma membrane residence of hyaluronan synthase is coupled to its enzymatic activity
    • Rilla K., Siiskonen H., Spicer A.P., Hyttinen J.M., Tammi M.I., Tammi R.H. Plasma membrane residence of hyaluronan synthase is coupled to its enzymatic activity. J. Biol. Chem. 2005, 280:31890-31897.
    • (2005) J. Biol. Chem. , vol.280 , pp. 31890-31897
    • Rilla, K.1    Siiskonen, H.2    Spicer, A.P.3    Hyttinen, J.M.4    Tammi, M.I.5    Tammi, R.H.6
  • 48
    • 84892642128 scopus 로고    scopus 로고
    • Extensive CD44-dependent hyaluronan coats on human bone marrow-derived mesenchymal stem cells produced by hyaluronan synthases HAS1, HAS2 and HAS3
    • Qu C., Rilla K., Tammi R., Tammi M., Kroger H., Lammi M.J. Extensive CD44-dependent hyaluronan coats on human bone marrow-derived mesenchymal stem cells produced by hyaluronan synthases HAS1, HAS2 and HAS3. Int. J. Biochem. Cell Biol. 2014, 48:45-54.
    • (2014) Int. J. Biochem. Cell Biol. , vol.48 , pp. 45-54
    • Qu, C.1    Rilla, K.2    Tammi, R.3    Tammi, M.4    Kroger, H.5    Lammi, M.J.6
  • 49
    • 84894184903 scopus 로고    scopus 로고
    • Hyaluronan: towards novel anti-cancer therapeutics
    • Karbownik M.S., Nowak J.Z. Hyaluronan: towards novel anti-cancer therapeutics. Pharmacol. Rep. 2013, 65:1056-1074.
    • (2013) Pharmacol. Rep. , vol.65 , pp. 1056-1074
    • Karbownik, M.S.1    Nowak, J.Z.2
  • 50
    • 84908341208 scopus 로고    scopus 로고
    • Low molecular weight hyaluronan mediated CD44 dependent induction of IL-6 and chemokines in human dermal fibroblasts potentiates innate immune response
    • Vistejnova L., Safrankova B., Nesporova K., Slavkovsky R., Hermannova M., Hosek P., Velebny V., Kubala L. Low molecular weight hyaluronan mediated CD44 dependent induction of IL-6 and chemokines in human dermal fibroblasts potentiates innate immune response. Cytokine 2014, 70(2):97-103. 10.1016/j.cyto.2014.07.006.
    • (2014) Cytokine , vol.70 , Issue.2 , pp. 97-103
    • Vistejnova, L.1    Safrankova, B.2    Nesporova, K.3    Slavkovsky, R.4    Hermannova, M.5    Hosek, P.6    Velebny, V.7    Kubala, L.8
  • 51
    • 70449395257 scopus 로고    scopus 로고
    • Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM-mediated signalling pathways involving Cdc2 and gamma-adducin
    • Matou-Nasri S., Gaffney J., Kumar S., Slevin M. Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM-mediated signalling pathways involving Cdc2 and gamma-adducin. Int. J. Oncol. 2009, 35:761-773.
    • (2009) Int. J. Oncol. , vol.35 , pp. 761-773
    • Matou-Nasri, S.1    Gaffney, J.2    Kumar, S.3    Slevin, M.4
  • 52
    • 84906861737 scopus 로고    scopus 로고
    • Transactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression
    • Lennon F.E., Mirzapoiazova T., Mambetsariev N., Mambetsariev B., Salgia R., Singleton P.A. Transactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression. J. Biol. Chem. 2014, 289:24043-24058.
    • (2014) J. Biol. Chem. , vol.289 , pp. 24043-24058
    • Lennon, F.E.1    Mirzapoiazova, T.2    Mambetsariev, N.3    Mambetsariev, B.4    Salgia, R.5    Singleton, P.A.6
  • 53
    • 84899817020 scopus 로고    scopus 로고
    • Low molecular weight hyaluronan induces lymphangiogenesis through LYVE-1-mediated signaling pathways
    • Wu M., Du Y., Liu Y., He Y., Yang C., Wang W., Gao F. Low molecular weight hyaluronan induces lymphangiogenesis through LYVE-1-mediated signaling pathways. PLoS One 2014, 9:e92857.
    • (2014) PLoS One , vol.9 , pp. e92857
    • Wu, M.1    Du, Y.2    Liu, Y.3    He, Y.4    Yang, C.5    Wang, W.6    Gao, F.7
  • 54
    • 84901626643 scopus 로고    scopus 로고
    • Tissue integrity signals communicated by high-molecular weight hyaluronan and the resolution of inflammation
    • Ruppert S.M., Hawn T.R., Arrigoni A., Wight T.N., Bollyky P.L. Tissue integrity signals communicated by high-molecular weight hyaluronan and the resolution of inflammation. Immunol. Res. 2014, 58:186-192.
    • (2014) Immunol. Res. , vol.58 , pp. 186-192
    • Ruppert, S.M.1    Hawn, T.R.2    Arrigoni, A.3    Wight, T.N.4    Bollyky, P.L.5
  • 55
    • 0033948419 scopus 로고    scopus 로고
    • Hyaluronic acid as an anti-angiogenic shield in the preovulatory rat follicle
    • Tempel C., Gilead A., Neeman M. Hyaluronic acid as an anti-angiogenic shield in the preovulatory rat follicle. Biol. Reprod. 2000, 63:134-140.
    • (2000) Biol. Reprod. , vol.63 , pp. 134-140
    • Tempel, C.1    Gilead, A.2    Neeman, M.3
  • 57
    • 84895806437 scopus 로고    scopus 로고
    • Specific sizes of hyaluronan oligosaccharides stimulate fibroblast migration and excisional wound repair
    • Tolg C., Telmer P., Turley E. Specific sizes of hyaluronan oligosaccharides stimulate fibroblast migration and excisional wound repair. PLoS One 2014, 9:e88479.
    • (2014) PLoS One , vol.9 , pp. e88479
    • Tolg, C.1    Telmer, P.2    Turley, E.3
  • 58
    • 36049007737 scopus 로고    scopus 로고
    • HAS3-related hyaluronan enhances biological activities necessary for metastasis of osteosarcoma cells
    • Tofuku K., Yokouchi M., Murayama T., Minami S., Komiya S. HAS3-related hyaluronan enhances biological activities necessary for metastasis of osteosarcoma cells. Int. J. Oncol. 2006, 29:175-183.
    • (2006) Int. J. Oncol. , vol.29 , pp. 175-183
    • Tofuku, K.1    Yokouchi, M.2    Murayama, T.3    Minami, S.4    Komiya, S.5
  • 60
    • 0037145745 scopus 로고    scopus 로고
    • Expression of hyaluronan synthase 2 or hyaluronidase 1 differentially affect the growth rate of transplantable colon carcinoma cell tumors
    • Jacobson A., Rahmanian M., Rubin K., Heldin P. Expression of hyaluronan synthase 2 or hyaluronidase 1 differentially affect the growth rate of transplantable colon carcinoma cell tumors. Int. J. Cancer 2002, 102:212-219.
    • (2002) Int. J. Cancer , vol.102 , pp. 212-219
    • Jacobson, A.1    Rahmanian, M.2    Rubin, K.3    Heldin, P.4
  • 61
    • 30344461304 scopus 로고    scopus 로고
    • Overexpression of hyaluronan synthases alters vascular smooth muscle cell phenotype and promotes monocyte adhesion
    • Wilkinson T.S., Bressler S.L., Evanko S.P., Braun K.R., Wight T.N. Overexpression of hyaluronan synthases alters vascular smooth muscle cell phenotype and promotes monocyte adhesion. J. Cell. Physiol. 2006, 206:378-385.
    • (2006) J. Cell. Physiol. , vol.206 , pp. 378-385
    • Wilkinson, T.S.1    Bressler, S.L.2    Evanko, S.P.3    Braun, K.R.4    Wight, T.N.5
  • 62
    • 77952698239 scopus 로고    scopus 로고
    • 4-Methylumbelliferone inhibits tumour cell growth and the activation of stromal hyaluronan synthesis by melanoma cell-derived factors
    • Edward M., Quinn J.A., Pasonen-Seppänen S.M., McCann B.A., Tammi R.H. 4-Methylumbelliferone inhibits tumour cell growth and the activation of stromal hyaluronan synthesis by melanoma cell-derived factors. Br. J. Dermatol. 2010, 162:1224-1232.
    • (2010) Br. J. Dermatol. , vol.162 , pp. 1224-1232
    • Edward, M.1    Quinn, J.A.2    Pasonen-Seppänen, S.M.3    McCann, B.A.4    Tammi, R.H.5
  • 63
    • 0023942845 scopus 로고
    • Hyaluronic acid modulates proliferation of mouse dermal fibroblasts in culture
    • Yoneda M., Yamagata M., Suzuki S., Kimata K. Hyaluronic acid modulates proliferation of mouse dermal fibroblasts in culture. J. Cell Sci. 1988, 90:265-273.
    • (1988) J. Cell Sci. , vol.90 , pp. 265-273
    • Yoneda, M.1    Yamagata, M.2    Suzuki, S.3    Kimata, K.4
  • 64
    • 0030917306 scopus 로고    scopus 로고
    • Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation
    • Kaya G., Rodriguez I., Jorcano J.L., Vassalli P., Stamenkovic I. Selective suppression of CD44 in keratinocytes of mice bearing an antisense CD44 transgene driven by a tissue-specific promoter disrupts hyaluronate metabolism in the skin and impairs keratinocyte proliferation. Genes Dev. 1997, 11:996-1007.
    • (1997) Genes Dev. , vol.11 , pp. 996-1007
    • Kaya, G.1    Rodriguez, I.2    Jorcano, J.L.3    Vassalli, P.4    Stamenkovic, I.5
  • 67
    • 77954850945 scopus 로고    scopus 로고
    • HA modulation of epidermal morphogenesis in an organotypic keratinocyte-fibroblast co-culture model
    • Gu H., Huang L., Wong Y.P., Burd A. HA modulation of epidermal morphogenesis in an organotypic keratinocyte-fibroblast co-culture model. Exp. Dermatol. 2010, 19:e336-e339.
    • (2010) Exp. Dermatol. , vol.19 , pp. e336-e339
    • Gu, H.1    Huang, L.2    Wong, Y.P.3    Burd, A.4
  • 68
    • 78049476715 scopus 로고    scopus 로고
    • Hyaluronan used for intradermal injections is incorporated into the pericellular matrix and promotes proliferation in human skin fibroblasts in vitro
    • Röck K., Fischer K., Fischer J.W. Hyaluronan used for intradermal injections is incorporated into the pericellular matrix and promotes proliferation in human skin fibroblasts in vitro. Dermatology 2010, 221:219-228.
    • (2010) Dermatology , vol.221 , pp. 219-228
    • Röck, K.1    Fischer, K.2    Fischer, J.W.3
  • 70
    • 84904341626 scopus 로고    scopus 로고
    • No influence of exogenous hyaluronan on the behavior of human cancer cells or endothelial cell capillary formation
    • Seino S., Takeshita F., Asari A., Masuda Y., Kunou M., Ochiya T. No influence of exogenous hyaluronan on the behavior of human cancer cells or endothelial cell capillary formation. J. Food Sci. 2014, 79:T1469-T1475.
    • (2014) J. Food Sci. , vol.79 , pp. T1469-T1475
    • Seino, S.1    Takeshita, F.2    Asari, A.3    Masuda, Y.4    Kunou, M.5    Ochiya, T.6
  • 73
    • 36648998690 scopus 로고    scopus 로고
    • Hyaluronic acid induces transglutaminase II to enhance cell motility; role of Rac1 and FAK in the induction of transglutaminase II
    • Kim Y., Park Y.W., Lee Y.S., Jeoung D. Hyaluronic acid induces transglutaminase II to enhance cell motility; role of Rac1 and FAK in the induction of transglutaminase II. Biotechnol. Lett. 2008, 30:31-39.
    • (2008) Biotechnol. Lett. , vol.30 , pp. 31-39
    • Kim, Y.1    Park, Y.W.2    Lee, Y.S.3    Jeoung, D.4
  • 75
    • 0036218443 scopus 로고    scopus 로고
    • Initial stages of cell-matrix adhesion can be mediated and modulated by cell-surface hyaluronan
    • Zimmerman E., Geiger B., Addadi L. Initial stages of cell-matrix adhesion can be mediated and modulated by cell-surface hyaluronan. Biophys. J. 2002, 82:1848-1857.
    • (2002) Biophys. J. , vol.82 , pp. 1848-1857
    • Zimmerman, E.1    Geiger, B.2    Addadi, L.3
  • 76
    • 5644223308 scopus 로고    scopus 로고
    • Spatial and temporal sequence of events in cell adhesion: from molecular recognition to focal adhesion assembly
    • Cohen M., Joester D., Geiger B., Addadi L. Spatial and temporal sequence of events in cell adhesion: from molecular recognition to focal adhesion assembly. Chembiochem 2004, 5:1393-1399.
    • (2004) Chembiochem , vol.5 , pp. 1393-1399
    • Cohen, M.1    Joester, D.2    Geiger, B.3    Addadi, L.4
  • 77
    • 84884683059 scopus 로고    scopus 로고
    • Hyaluronan-based pericellular matrix: substrate electrostatic charges and early cell adhesion events
    • Fotia C., Messina G.M., Marletta G., Baldini N., Ciapetti G. Hyaluronan-based pericellular matrix: substrate electrostatic charges and early cell adhesion events. Eur. Cell Mater. 2013, 26:133-149.
    • (2013) Eur. Cell Mater. , vol.26 , pp. 133-149
    • Fotia, C.1    Messina, G.M.2    Marletta, G.3    Baldini, N.4    Ciapetti, G.5
  • 78
    • 0033977292 scopus 로고    scopus 로고
    • A role for the cell adhesion molecule CD44 and sulfation in leukocyte-endothelial cell adhesion during an inflammatory response?
    • Johnson P., Maiti A., Brown K.L., Li R. A role for the cell adhesion molecule CD44 and sulfation in leukocyte-endothelial cell adhesion during an inflammatory response?. Biochem. Pharmacol. 2000, 59:455-465.
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 455-465
    • Johnson, P.1    Maiti, A.2    Brown, K.L.3    Li, R.4
  • 79
    • 4143149778 scopus 로고    scopus 로고
    • CD44 potentiates the adherence of metastatic prostate and breast cancer cells to bone marrow endothelial cells
    • Draffin J.E., McFarlane S., Hill A., Johnston P.G., Waugh D.J. CD44 potentiates the adherence of metastatic prostate and breast cancer cells to bone marrow endothelial cells. Cancer Res. 2004, 64:5702-5711.
    • (2004) Cancer Res. , vol.64 , pp. 5702-5711
    • Draffin, J.E.1    McFarlane, S.2    Hill, A.3    Johnston, P.G.4    Waugh, D.J.5
  • 81
    • 77954938543 scopus 로고    scopus 로고
    • Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal squamous carcinoma cells
    • Twarock S., Tammi M.I., Savani R.C., Fischer J.W. Hyaluronan stabilizes focal adhesions, filopodia, and the proliferative phenotype in esophageal squamous carcinoma cells. J. Biol. Chem. 2010, 285:23276-23284.
    • (2010) J. Biol. Chem. , vol.285 , pp. 23276-23284
    • Twarock, S.1    Tammi, M.I.2    Savani, R.C.3    Fischer, J.W.4
  • 82
    • 4644288126 scopus 로고    scopus 로고
    • The hyaluronan synthesis inhibitor 4-methylumbelliferone prevents keratinocyte activation and epidermal hyperproliferation induced by epidermal growth factor
    • Rilla K., Pasonen-Seppänen S., Rieppo J., Tammi M., Tammi R. The hyaluronan synthesis inhibitor 4-methylumbelliferone prevents keratinocyte activation and epidermal hyperproliferation induced by epidermal growth factor. J. Invest. Dermatol. 2004, 123:708-714.
    • (2004) J. Invest. Dermatol. , vol.123 , pp. 708-714
    • Rilla, K.1    Pasonen-Seppänen, S.2    Rieppo, J.3    Tammi, M.4    Tammi, R.5
  • 83
    • 31444449011 scopus 로고    scopus 로고
    • Dynamic study of the transition from hyaluronan- to integrin-mediated adhesion in chondrocytes
    • Cohen M., Kam Z., Addadi L., Geiger B. Dynamic study of the transition from hyaluronan- to integrin-mediated adhesion in chondrocytes. EMBO J. 2006, 25:302-311.
    • (2006) EMBO J. , vol.25 , pp. 302-311
    • Cohen, M.1    Kam, Z.2    Addadi, L.3    Geiger, B.4
  • 84
    • 37249083542 scopus 로고    scopus 로고
    • Cell-matrix adhesion complexes: master control machinery of cell migration
    • Lock J.G., Wehrle-Haller B., Stromblad S. Cell-matrix adhesion complexes: master control machinery of cell migration. Semin. Cancer Biol. 2008, 18:65-76.
    • (2008) Semin. Cancer Biol. , vol.18 , pp. 65-76
    • Lock, J.G.1    Wehrle-Haller, B.2    Stromblad, S.3
  • 85
    • 0035253672 scopus 로고    scopus 로고
    • Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression
    • Assoian R.K., Schwartz M.A. Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression. Curr. Opin. Genet. Dev. 2001, 11:48-53.
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 48-53
    • Assoian, R.K.1    Schwartz, M.A.2
  • 86
    • 0034168037 scopus 로고    scopus 로고
    • Protein kinase C-mediated regulation of the cell cycle
    • Black J.D. Protein kinase C-mediated regulation of the cell cycle. Front. Biosci. 2000, 5:D406-D423.
    • (2000) Front. Biosci. , vol.5 , pp. D406-D423
    • Black, J.D.1
  • 88
    • 33744974769 scopus 로고    scopus 로고
    • Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression
    • Yamamoto T., Ebisuya M., Ashida F., Okamoto K., Yonehara S., Nishida E. Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression. Curr. Biol. 2006, 16:1171-1182.
    • (2006) Curr. Biol. , vol.16 , pp. 1171-1182
    • Yamamoto, T.1    Ebisuya, M.2    Ashida, F.3    Okamoto, K.4    Yonehara, S.5    Nishida, E.6
  • 89
    • 77953387301 scopus 로고    scopus 로고
    • Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation
    • Voisin L., Saba-El-Leil M.K., Julien C., Fremin C., Meloche S. Genetic demonstration of a redundant role of extracellular signal-regulated kinase 1 (ERK1) and ERK2 mitogen-activated protein kinases in promoting fibroblast proliferation. Mol. Cell. Biol. 2010, 30:2918-2932.
    • (2010) Mol. Cell. Biol. , vol.30 , pp. 2918-2932
    • Voisin, L.1    Saba-El-Leil, M.K.2    Julien, C.3    Fremin, C.4    Meloche, S.5
  • 92
    • 21344456180 scopus 로고    scopus 로고
    • The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma
    • Meier F., Schittek B., Busch S., Garbe C., Smalley K., Satyamoorthy K., Li G., Herlyn M. The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma. Front. Biosci. 2005, 10:2986-3001.
    • (2005) Front. Biosci. , vol.10 , pp. 2986-3001
    • Meier, F.1    Schittek, B.2    Busch, S.3    Garbe, C.4    Smalley, K.5    Satyamoorthy, K.6    Li, G.7    Herlyn, M.8
  • 93
    • 0028241389 scopus 로고
    • Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity
    • Hall C.L., Wang C., Lange L.A., Turley E.A. Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity. J. Cell Biol. 1994, 126:575-588.
    • (1994) J. Cell Biol. , vol.126 , pp. 575-588
    • Hall, C.L.1    Wang, C.2    Lange, L.A.3    Turley, E.A.4
  • 94
    • 0029838320 scopus 로고    scopus 로고
    • Pp60(c-src) is required for cell locomotion regulated by the hyaluronanreceptor RHAMM
    • Hall C.L., Lange L.A., Prober D.A., Zhang S., Turley E.A. pp60(c-src) is required for cell locomotion regulated by the hyaluronanreceptor RHAMM. Oncogene 1996, 13:2213-2224.
    • (1996) Oncogene , vol.13 , pp. 2213-2224
    • Hall, C.L.1    Lange, L.A.2    Prober, D.A.3    Zhang, S.4    Turley, E.A.5
  • 96
    • 84921301665 scopus 로고    scopus 로고
    • Integrin regulation of epidermal functions in wounds
    • Longmate W.M., Dipersio C.M. Integrin regulation of epidermal functions in wounds. Adv. Wound Care 2014, 3:229-246.
    • (2014) Adv. Wound Care , vol.3 , pp. 229-246
    • Longmate, W.M.1    Dipersio, C.M.2
  • 98
    • 0031225074 scopus 로고    scopus 로고
    • Control of the G1 phase cyclin-dependent kinases by mitogenic growth factors and the extracellular matrix
    • Assoian R.K. Control of the G1 phase cyclin-dependent kinases by mitogenic growth factors and the extracellular matrix. Cytokine Growth Factor Rev. 1997, 8:165-170.
    • (1997) Cytokine Growth Factor Rev. , vol.8 , pp. 165-170
    • Assoian, R.K.1
  • 99
    • 0141483383 scopus 로고    scopus 로고
    • Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells
    • Conner S.R., Scott G., Aplin A.E. Adhesion-dependent activation of the ERK1/2 cascade is by-passed in melanoma cells. J. Biol. Chem. 2003, 278:34548-34554.
    • (2003) J. Biol. Chem. , vol.278 , pp. 34548-34554
    • Conner, S.R.1    Scott, G.2    Aplin, A.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.