메뉴 건너뛰기




Volumn 16, Issue 7, 2015, Pages 15481-15496

Overexpression of the MRI reporter genes ferritin and transferrin receptor affect iron homeostasis and produce limited contrast in mesenchymal stem cells

Author keywords

Biogenic nanoparticles; Cell tracking; Chick embryo; Ferritin; Magnetic resonance; Reporter genes; Transferrin receptor

Indexed keywords

ASCORBIC ACID; CD71 ANTIGEN; COMPLEMENTARY DNA; ELONGATION FACTOR 1ALPHA; ENHANCED GREEN FLUORESCENT PROTEIN; FERRIC CITRATE; FERRITIN; IRON REGULATORY FACTOR; LENTIVIRUS VECTOR; MESSENGER RNA; RED FLUORESCENT PROTEIN; TRANSFERRIN; APOFERRITIN; IRON; TFRC PROTEIN, MOUSE; TRANSFERRIN RECEPTOR;

EID: 84939526673     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms160715481     Document Type: Article
Times cited : (45)

References (36)
  • 1
    • 84863791585 scopus 로고    scopus 로고
    • Molecular imaging of stem cells
    • Girard, L., Ed.; Harvard Stem Cell Institute: Cambridge, MA, USA, (accessed on 5 May 2015)
    • Rodriguez-Porcel, M.; Wu, J.C.; Gambhir, S.S. Molecular imaging of stem cells. In Stembook; Girard, L., Ed.; Harvard Stem Cell Institute: Cambridge, MA, USA, 2009. Available online: http://www.stembook.org (accessed on 5 May 2015).
    • (2009) Stembook
    • Rodriguez-Porcel, M.1    Wu, J.C.2    Gambhir, S.S.3
  • 3
    • 84858689120 scopus 로고    scopus 로고
    • Long-term tracking of cells using inorganic nanoparticles as contrast agents: Are we there yet?
    • Taylor, A.; Wilson, K.M.; Murray, P.; Fernig, D.G.; Levy, R. Long-term tracking of cells using inorganic nanoparticles as contrast agents: Are we there yet? Chem. Soc. Rev. 2012, 41, 2707-2717.
    • (2012) Chem. Soc. Rev. , vol.41 , pp. 2707-2717
    • Taylor, A.1    Wilson, K.M.2    Murray, P.3    Fernig, D.G.4    Levy, R.5
  • 4
    • 68149172455 scopus 로고    scopus 로고
    • In vivo MRI cell tracking: Clinical studies
    • Bulte, J.W.M. In vivo MRI cell tracking: Clinical studies. Am. J. Roentgenol. 2009, 193, 314-325.
    • (2009) Am. J. Roentgenol. , vol.193 , pp. 314-325
    • Bulte, J.W.M.1
  • 6
    • 84939501011 scopus 로고    scopus 로고
    • In vivo cell tracking with bioluminescence imaging
    • Kim, J.; Kalimuthu, S.; Ahn, B.-C. In vivo cell tracking with bioluminescence imaging. Nucl. Med. Mol. Imaging 2015, 49, 3-10.
    • (2015) Nucl. Med. Mol. Imaging , vol.49 , pp. 3-10
    • Kim, J.1    Kalimuthu, S.2    Ahn, B.-C.3
  • 7
    • 84879524638 scopus 로고    scopus 로고
    • MRI reporter genes: Application to imaging of cell survival, proliferation, migration, and differentiation
    • Vandsburger, M.H.; Radoul, M.; Cohen, B.; Neeman, M. MRI reporter genes: Application to imaging of cell survival, proliferation, migration, and differentiation. NMR Biomed. 2013, 26, 872-884.
    • (2013) NMR Biomed. , vol.26 , pp. 872-884
    • Vandsburger, M.H.1    Radoul, M.2    Cohen, B.3    Neeman, M.4
  • 8
    • 50949102412 scopus 로고    scopus 로고
    • Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network
    • Muckenthaler, M.U.; Galy, B.; Hentze, M.W. Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network. Ann. Rev. Nutr. 2008, 28, 197-213.
    • (2008) Ann. Rev. Nutr. , vol.28 , pp. 197-213
    • Muckenthaler, M.U.1    Galy, B.2    Hentze, M.W.3
  • 9
    • 67349100157 scopus 로고    scopus 로고
    • Ferritins: A family of molecules for iron storage, antioxidation and more
    • Arosio, P.; Ingrassia, R.; Cavadini, P. Ferritins: A family of molecules for iron storage, antioxidation and more. Biochim. Biophys. Acta 2009, 1790, 589-599.
    • (2009) Biochim. Biophys. Acta , vol.1790 , pp. 589-599
    • Arosio, P.1    Ingrassia, R.2    Cavadini, P.3
  • 10
    • 0033617958 scopus 로고    scopus 로고
    • Mineralization in ferritin: An efficient means of iron storage
    • Chasteen, N.D.; Harrison, P.M. Mineralization in ferritin: An efficient means of iron storage. J. Struct. Biol. 1999, 126, 182-194.
    • (1999) J. Struct. Biol. , vol.126 , pp. 182-194
    • Chasteen, N.D.1    Harrison, P.M.2
  • 11
    • 0024245282 scopus 로고
    • Mechanism of ferritin iron uptake: Activity of the H-chain and deletion mapping of the ferro-oxidase site. A study of iron uptake and ferro-oxidase activity of human liver, recombinant H-chain ferritins, and of two H-chain deletion mutants
    • Levi, S.; Luzzago, A.; Cesareni, G.; Cozzi, A.; Franceschinelli, F.; Albertini, A.; Arosio, P. Mechanism of ferritin iron uptake: Activity of the H-chain and deletion mapping of the ferro-oxidase site. A study of iron uptake and ferro-oxidase activity of human liver, recombinant H-chain ferritins, and of two H-chain deletion mutants. J. Biol. Chem. 1988, 263, 18086-18092.
    • (1988) J. Biol. Chem. , vol.263 , pp. 18086-18092
    • Levi, S.1    Luzzago, A.2    Cesareni, G.3    Cozzi, A.4    Franceschinelli, F.5    Albertini, A.6    Arosio, P.7
  • 12
    • 34249686049 scopus 로고    scopus 로고
    • Ferritin and ferritin isoforms I: Structure-function relationships, synthesis, degradation and secretion
    • Koorts, A.M.; Viljoen, M. Ferritin and ferritin isoforms I: Structure-function relationships, synthesis, degradation and secretion. Arch. Physiol. Biochem. 2007, 113, 30-54.
    • (2007) Arch. Physiol. Biochem. , vol.113 , pp. 30-54
    • Koorts, A.M.1    Viljoen, M.2
  • 13
    • 0027198736 scopus 로고
    • Production and characterization of recombinant heteropolymers of human ferritin H and L chains
    • Santambrogio, P.; Levi, S.; Cozzi, A.; Rovida, E.; Albertini, A.; Arosio, P. Production and characterization of recombinant heteropolymers of human ferritin H and L chains. J. Biol. Chem. 1993, 268, 12744-12748.
    • (1993) J. Biol. Chem. , vol.268 , pp. 12744-12748
    • Santambrogio, P.1    Levi, S.2    Cozzi, A.3    Rovida, E.4    Albertini, A.5    Arosio, P.6
  • 14
    • 67749143592 scopus 로고    scopus 로고
    • Visualization of in vivo electroporation-mediated transgene expression in experimental tumors by optical and magnetic resonance imaging
    • Aung, W.; Hasegawa, S.; Koshikawa-Yano, M.; Obata, T.; Ikehira, H.; Furukawa, T.; Aoki, I.; Saga, T. Visualization of in vivo electroporation-mediated transgene expression in experimental tumors by optical and magnetic resonance imaging. Gene Ther. 2009, 16, 830-839.
    • (2009) Gene Ther. , vol.16 , pp. 830-839
    • Aung, W.1    Hasegawa, S.2    Koshikawa-Yano, M.3    Obata, T.4    Ikehira, H.5    Furukawa, T.6    Aoki, I.7    Saga, T.8
  • 15
    • 77956931062 scopus 로고    scopus 로고
    • In vivo imaging of tumor transduced with bimodal lentiviral vector encoding human ferritin and green fluorescent protein on a 1.5 t clinical magnetic resonance scanner
    • Kim, H.S.; Cho, H.R.; Choi, S.H.; Woo, J.S.; Moon, W.K. In vivo imaging of tumor transduced with bimodal lentiviral vector encoding human ferritin and green fluorescent protein on a 1.5 t clinical magnetic resonance scanner. Cancer Res. 2010, 70, 7315-7324.
    • (2010) Cancer Res. , vol.70 , pp. 7315-7324
    • Kim, H.S.1    Cho, H.R.2    Choi, S.H.3    Woo, J.S.4    Moon, W.K.5
  • 16
    • 84859644480 scopus 로고    scopus 로고
    • Imaging and quantification of metastatic melanoma cells in lymph nodes with a ferritin mr reporter in living mice
    • Choi, S.H.; Cho, H.R.; Kim, H.S.; Kim, Y.H.; Kang, K.W.; Kim, H.; Moon, W.K. Imaging and quantification of metastatic melanoma cells in lymph nodes with a ferritin mr reporter in living mice. NMR Biomed. 2012, 25, 737-745.
    • (2012) NMR Biomed. , vol.25 , pp. 737-745
    • Choi, S.H.1    Cho, H.R.2    Kim, H.S.3    Kim, Y.H.4    Kang, K.W.5    Kim, H.6    Moon, W.K.7
  • 17
    • 84859729358 scopus 로고    scopus 로고
    • Efficiency of ferritin as an MRI reporter gene in NPC cells is enhanced by iron supplementation
    • Feng, Y.; Liu, Q.; Zhu, J.; Xie, F.; Li, L. Efficiency of ferritin as an MRI reporter gene in NPC cells is enhanced by iron supplementation. J. Biomed. Biotechnol. 2012, 2012, 434878, doi:10.1155/2012/434878.
    • (2012) J. Biomed. Biotechnol. , vol.2012
    • Feng, Y.1    Liu, Q.2    Zhu, J.3    Xie, F.4    Li, L.5
  • 18
  • 20
    • 77956490539 scopus 로고    scopus 로고
    • Ferritin overexpression for noninvasive magnetic resonance imaging-based tracking of stem cells transplanted into the heart
    • Naumova, A.V.; Reinecke, H.; Yarnykh, V.; Deem, J.; Yuan, C.; Murry, C.E. Ferritin overexpression for noninvasive magnetic resonance imaging-based tracking of stem cells transplanted into the heart. Mol. Imaging 2010, 9, 201-210.
    • (2010) Mol. Imaging , vol.9 , pp. 201-210
    • Naumova, A.V.1    Reinecke, H.2    Yarnykh, V.3    Deem, J.4    Yuan, C.5    Murry, C.E.6
  • 22
    • 17644394164 scopus 로고    scopus 로고
    • A new transgene reporter for in vivo magnetic resonance imaging
    • Genove, G.; DeMarco, U.; Xu, H.; Goins, W.; Ahrens, E. A new transgene reporter for in vivo magnetic resonance imaging. Nat. Med. 2005, 11, 450-454.
    • (2005) Nat. Med. , vol.11 , pp. 450-454
    • Genove, G.1    DeMarco, U.2    Xu, H.3    Goins, W.4    Ahrens, E.5
  • 23
    • 84882243134 scopus 로고    scopus 로고
    • Quantification of HSV-1-mediated expression of the ferritin MRI reporter in the mouse brain
    • Iordanova, B.; Goins, W.F.; Clawson, D.S.; Hitchens, T.K.; Ahrens, E.T. Quantification of HSV-1-mediated expression of the ferritin MRI reporter in the mouse brain. Gene Ther. 2013, 20, 589-596.
    • (2013) Gene Ther. , vol.20 , pp. 589-596
    • Iordanova, B.1    Goins, W.F.2    Clawson, D.S.3    Hitchens, T.K.4    Ahrens, E.T.5
  • 24
    • 84883402576 scopus 로고    scopus 로고
    • Engineered mitochondrial ferritin as a magnetic resonance imaging reporter in mouse olfactory epithelium
    • Iordanova, B.; Hitchens, T.K.; Robison, C.S.; Ahrens, E.T. Engineered mitochondrial ferritin as a magnetic resonance imaging reporter in mouse olfactory epithelium. PLoS ONE 2013, 8, e72720.
    • (2013) PLoS ONE , vol.8
    • Iordanova, B.1    Hitchens, T.K.2    Robison, C.S.3    Ahrens, E.T.4
  • 25
    • 77956477063 scopus 로고    scopus 로고
    • Design and characterization of a chimeric ferritin with enhanced iron loading and transverse NMR relaxation rate
    • Iordanova, B.; Robison, C.S.; Ahrens, E.T. Design and characterization of a chimeric ferritin with enhanced iron loading and transverse NMR relaxation rate. J. Biol. Inorg. Chem. 2010, 15, 957-965.
    • (2010) J. Biol. Inorg. Chem. , vol.15 , pp. 957-965
    • Iordanova, B.1    Robison, C.S.2    Ahrens, E.T.3
  • 27
  • 28
    • 84880031116 scopus 로고    scopus 로고
    • Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism
    • Lane, D.J.R.; Chikhani, S.; Richardson, V.; Richardson, D.R. Transferrin iron uptake is stimulated by ascorbate via an intracellular reductive mechanism. Biochim. Biophys. Acta 2013, 1833, 1527-1541.
    • (2013) Biochim. Biophys. Acta , vol.1833 , pp. 1527-1541
    • Lane, D.J.R.1    Chikhani, S.2    Richardson, V.3    Richardson, D.R.4
  • 29
    • 83055194363 scopus 로고    scopus 로고
    • In vivo magnetic resonance imaging of ferritin-based reporter visualizes native neuroblast migration
    • Iordanova, B.; Ahrens, E.T. In vivo magnetic resonance imaging of ferritin-based reporter visualizes native neuroblast migration. Neuroimage 2012, 59, 1004-1012.
    • (2012) Neuroimage , vol.59 , pp. 1004-1012
    • Iordanova, B.1    Ahrens, E.T.2
  • 32
    • 84903550341 scopus 로고    scopus 로고
    • Assessing the efficacy of nano- and micro-sized magnetic particles as contrast agents for MRI cell tracking
    • Taylor, A.; Herrmann, A.; Moss, D.; Sée, V.; Davies, K.; Williams, S.; Murray, P. Assessing the efficacy of nano- and micro-sized magnetic particles as contrast agents for MRI cell tracking. PLoS ONE 2014, 9, e100259.
    • (2014) PLoS ONE , vol.9
    • Taylor, A.1    Herrmann, A.2    Moss, D.3    Sée, V.4    Davies, K.5    Williams, S.6    Murray, P.7
  • 33
    • 0034682761 scopus 로고    scopus 로고
    • Overexpression of wild type and mutated human ferritin H-chain in hela cells: In vivo role of ferritin ferroxidase activity
    • Cozzi, A.; Corsi, B.; Levi, S.; Santambrogio, P.; Albertini, A.; Arosio, P. Overexpression of wild type and mutated human ferritin H-chain in hela cells: In vivo role of ferritin ferroxidase activity. J. Biol. Chem. 2000, 275, 25122-25129.
    • (2000) J. Biol. Chem. , vol.275 , pp. 25122-25129
    • Cozzi, A.1    Corsi, B.2    Levi, S.3    Santambrogio, P.4    Albertini, A.5    Arosio, P.6
  • 34
    • 0030060705 scopus 로고    scopus 로고
    • Overexpression of the ferritin H subunit in cultured erythroid cells changes the intracellular iron distribution
    • Picard, V.; Renaudie, F.; Porcher, C.; Hentze, M.G.B.; Beaumont, C. Overexpression of the ferritin H subunit in cultured erythroid cells changes the intracellular iron distribution. Blood 1996, 87, 2057-2064.
    • (1996) Blood , vol.87 , pp. 2057-2064
    • Picard, V.1    Renaudie, F.2    Porcher, C.3    Hentze, M.G.B.4    Beaumont, C.5
  • 36
    • 64749107970 scopus 로고    scopus 로고
    • Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors
    • Kutner, R.; Zhang, X.; Reiser, J. Production, concentration and titration of pseudotyped HIV-1-based lentiviral vectors. Nat. Protoc. 2009, 4, 495-505.
    • (2009) Nat. Protoc. , vol.4 , pp. 495-505
    • Kutner, R.1    Zhang, X.2    Reiser, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.