Evaluation of the specificity and sensitivity of ferritin as an MRI reporter gene in the mouse brain using lentiviral and adeno-associated viral vectors

Gene Therapy

Volumn 18, Issue 6, 2011, Pages 594-605

  Vande Velde, G ^a,b   Rangarajan, J R ^a,b   Toelen, J ^c   Dresselaers, T ^a,b   Ibrahimi, A ^b,c   Krylychkina, O ^a   Vreys, R ^d   Van Der Linden, A ^d   Maes, F ^a,b   Debyser, Z ^a,b,c   Himmelreich, U ^a,b   Baekelandt, V ^a,b,e  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b KU Leuven   (Belgium)

^c DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^d UNIVERSITY OF ANTWERP   (Belgium)

^e Laboratory for Molecular Virology and Gene Therapy   (Belgium)

Author keywords

brain; ferritin; molecular imaging; mouse; reporter gene; viral vectors

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; FERRITIN; FIREFLY LUCIFERASE; LENTIVIRUS VECTOR; PARVOVIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CONTRAST ENHANCEMENT; CONTROLLED STUDY; GENE EXPRESSION; GENE THERAPY; HISTOLOGY; IN VIVO STUDY; LENTIVIRINAE; MOLECULAR IMAGING; MOUSE; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; BRAIN; CELL LINE; DEPENDOVIRUS; FERRITINS; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GENETIC VECTORS; HUMANS; LENTIVIRUS; MAGNETIC RESONANCE IMAGING; MICE; MOLECULAR IMAGING; SENSITIVITY AND SPECIFICITY;

MUS; RODENTIA;

EID: 79958248563     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2011.2     Document Type: Article

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