Proteomic analysis reveals KRIT1 as a modulator for the antioxidant effects of valproic acid in human bone-marrow mesenchymal stromal cells

Drug and Chemical Toxicology

Volumn 38, Issue 3, 2015, Pages 286-292

  Jung, Kyoung Hwa ^a   Han, Dal Mu Ri ^a   Jeong, Sin Gu ^b   Choi, Mi Ran ^a   Chai, Young Gyu ^a   Cho, Goang Won ^b  

^a Hanyang University   (South Korea)

^b Chosun University   (South Korea)

Author keywords

Antioxidant effect; Bone marrowmesenchymal stromal cells (BM MSCs); KRIT1; Mesenchymal stromal cells (MSCs); Proteomic analysis; Valproic acid (VPA)

Indexed keywords

CYCLIN D1; KRIT1 PROTEIN; PROTEIN; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; VALPROIC ACID; ANTIOXIDANT; CCND1 PROTEIN, HUMAN; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; HYDROGEN PEROXIDE; KRIT1 PROTEIN, HUMAN; MANGANESE SUPEROXIDE DISMUTASE; MICROTUBULE ASSOCIATED PROTEIN; ONCOPROTEIN; OXIDIZING AGENT; SUPEROXIDE DISMUTASE;

ARTICLE; BONE MARROW CELL; CELL VIABILITY; CONTROLLED STUDY; GENE SILENCING; HOMEOSTASIS; HUMAN; HUMAN CELL; ISOELECTRIC FOCUSING; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MESENCHYMAL STROMA CELL; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; MASS SPECTROMETRY; METABOLISM; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

ANTIOXIDANTS; BLOTTING, WESTERN; BONE MARROW CELLS; CELLS, CULTURED; CYCLIN D1; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; HYDROGEN PEROXIDE; MESENCHYMAL STROMAL CELLS; MICROTUBULE-ASSOCIATED PROTEINS; OXIDANTS; OXIDATIVE STRESS; PROTEOMICS; PROTO-ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SUPEROXIDE DISMUTASE; TRANSFECTION; UP-REGULATION; VALPROIC ACID;

EID: 84939496076     PISSN: 01480545     EISSN: 15256014     Source Type: Journal    
DOI: 10.3109/01480545.2014.951762     Document Type: Article

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