Platelet gpiba binding to von willebrand factor under fluid shear: Contributions of the D'D3-domain, A1-domain flanking peptide and O-linked glycans

Journal of the American Heart Association

Volumn 3, Issue 5, 2014, Pages

  Madabhushi, Sri R ^a   Zhang, Changjie ^a   Kelkar, Anju ^a   Dayananda, Kannayakanahalli M ^a   Neelamegham, Sriram ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Blood platelets; Cell adhesion; Microfluidics; Thrombosis; Von Willebrand factor

Indexed keywords

GLYCAN; PROTEIN GPIB ALPHA; RECOMBINANT PROTEIN; RISTOCETIN; THROMBOCYTE RECEPTOR; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR; ADHESION RECEPTOR; BIOACTIVE PEPTIDE A1, RANA ESCULENTA; PEPTIDE; POLYSACCHARIDE; THROMBIN RECEPTOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BLOOD CLOTTING; CONTROLLED STUDY; DEGLYCOSYLATION; DIMERIZATION; DISSOCIATION CONSTANT; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN IMMOBILIZATION; PROTEIN PROTEIN INTERACTION; SHEAR STRESS; SURFACE PLASMON RESONANCE; THROMBOCYTE AGGREGATION; BINDING SITE; BLOOD CLOTTING PARAMETERS; CHEMISTRY; FLUID SHIFT; HEMODYNAMICS; HUMAN; IN VITRO STUDY; METABOLISM; MICROFLUIDICS; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; SENSITIVITY AND SPECIFICITY; THROMBOCYTE; THROMBOSIS;

BINDING SITES; BLOOD PLATELETS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUID SHIFTS; HEMODYNAMICS; HUMANS; IN VITRO TECHNIQUES; MICROFLUIDICS; PEPTIDES; PLATELET AGGREGATION; PLATELET FUNCTION TESTS; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; POLYSACCHARIDES; SENSITIVITY AND SPECIFICITY; THROMBOSIS; VON WILLEBRAND FACTOR;

EID: 84939461343     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.114.001420     Document Type: Article

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