The linker between the D3 and A1 domains of vWF suppresses A1-GPIba catch bonds by site-specific binding to the A1 domain

Protein Science

Volumn 22, Issue 8, 2013, Pages 1049-1059

  Tischer, Alexander ^a   Cruz, Miguel A ^b   Auton, Matthew ^a  

^a MAYO CLINIC   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Catch bonds; Circular dichroism; Differential scanning calorimetry; Fluorescence; Irreversible denaturation; Parallel plate flow chamber; Pause time; Peptide binding; Thermodynamics; Von Willebrand factor

Indexed keywords

GLYCOPROTEIN IB ALPHA; UREA; VON WILLEBRAND FACTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CIRCULAR DICHROISM; DIFFERENTIAL SCANNING CALORIMETRY; ENTHALPY; FLUORESCENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN IMMOBILIZATION; PROTEIN UNFOLDING; SHEAR STRESS; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGLUTINATION; TRANSITION TEMPERATURE;

CATCH BONDS; DIFFERENTIAL SCANNING CALORIMETRY; FLUORESCENCE; IRREVERSIBLE DENATURATION; PARALLEL PLATE FLOW CHAMBER; PAUSE TIME; PEPTIDE BINDING CIRCULAR DICHROISM; THERMODYNAMICS; VON WILLEBRAND FACTOR;

AMINO ACID SEQUENCE; BINDING SITES; BLOOD PLATELETS; HUMANS; MEMBRANE GLYCOPROTEINS; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; VON WILLEBRAND FACTOR;

EID: 84881283044     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.2294     Document Type: Article

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