-
1
-
-
84864003561
-
PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation
-
Bobrovnikova-Marjon E, Pytel D, Riese MJ, Vaites L P, Singh N, Koretzky GA, Witze ES, Diehl JA (2012). PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation. Mol Cell Biol 32, 2268-2278.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 2268-2278
-
-
Bobrovnikova-Marjon, E.1
Pytel, D.2
Riese, M.J.3
Vaites, L.P.4
Singh, N.5
Koretzky, G.A.6
Witze, E.S.7
Diehl, J.A.8
-
2
-
-
84929428266
-
Cleavage of BLOC1S1 mRNA by IRE1 is sequence specifc, temporally separate from XBP1 splicing, and dispensable for cell viability under acute endoplasmic reticulum stress
-
Bright MD, Itzhak DN, Wardell C P, Morgan GJ, Davies FE (2015). Cleavage of BLOC1S1 mRNA by IRE1 is sequence specifc, temporally separate from XBP1 splicing, and dispensable for cell viability under acute endoplasmic reticulum stress. Mol Cell Biol 35, 2186-2202.
-
(2015)
Mol Cell Biol
, vol.35
, pp. 2186-2202
-
-
Bright, M.D.1
Itzhak, D.N.2
Wardell, C.P.3
Morgan, G.J.4
Davies, F.E.5
-
3
-
-
0037011917
-
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA
-
Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, Harding H P, Clark SG, Ron D (2002). IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 415, 92-96.
-
(2002)
Nature
, vol.415
, pp. 92-96
-
-
Calfon, M.1
Zeng, H.2
Urano, F.3
Till, J.H.4
Hubbard, S.R.5
Harding, H.P.6
Clark, S.G.7
Ron, D.8
-
4
-
-
84877870687
-
The unfolded protein response element IRE1alpha senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling
-
Cho JA, Lee AH, Platzer B, Cross BC, Gardner BM, De Luca H, Luong P, Harding H P, Glimcher LH, Walter P, et al. (2013). The unfolded protein response element IRE1alpha senses bacterial proteins invading the ER to activate RIG-I and innate immune signaling. Cell Host Microbe 13, 558-569.
-
(2013)
Cell Host Microbe
, vol.13
, pp. 558-569
-
-
Cho, J.A.1
Lee, A.H.2
Platzer, B.3
Cross, B.C.4
Gardner, B.M.5
De Luca, H.6
Luong, P.7
Harding, H.P.8
Glimcher, L.H.9
Walter, P.10
-
6
-
-
84887609926
-
Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila
-
Coelho DS, Cairrão F, Zeng X, Pires E, Coelho AV, Ron D, Ryoo HD, Domingos PM (2013). Xbp1-independent Ire1 signaling is required for photoreceptor differentiation and rhabdomere morphogenesis in Drosophila. Cell Rep 5, 791-801.
-
(2013)
Cell Rep
, vol.5
, pp. 791-801
-
-
Coelho, D.S.1
Cairrão, F.2
Zeng, X.3
Pires, E.4
Coelho, A.V.5
Ron, D.6
Ryoo, H.D.7
Domingos, P.M.8
-
7
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
Cullinan SB, Zhang D, Hannink M, Arvisais E, Kaufman RJ, Diehl JA (2003). Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival. Mol Cell Biol 23, 7198-7209.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 7198-7209
-
-
Cullinan, S.B.1
Zhang, D.2
Hannink, M.3
Arvisais, E.4
Kaufman, R.J.5
Diehl, J.A.6
-
8
-
-
34547114745
-
IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-A expression and contributes to angiogenesis and tumor growth in vivo
-
Drogat B, Auguste P, Nguyen DT, Bouchecareilh M, Pineau R, Nalbantoglu J, Kaufman RJ, Chevet E, Bikfalvi A, Moenner M (2007). IRE1 signaling is essential for ischemia-induced vascular endothelial growth factor-A expression and contributes to angiogenesis and tumor growth in vivo. Cancer Res 67, 6700-6707.
-
(2007)
Cancer Res
, vol.67
, pp. 6700-6707
-
-
Drogat, B.1
Auguste, P.2
Nguyen, D.T.3
Bouchecareilh, M.4
Pineau, R.5
Nalbantoglu, J.6
Kaufman, R.J.7
Chevet, E.8
Bikfalvi, A.9
Moenner, M.10
-
9
-
-
84871911924
-
Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells
-
Gaddam D, Stevens N, Hollien J (2013). Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells. Mol Biol Cell 24, 14-20.
-
(2013)
Mol Biol Cell
, vol.24
, pp. 14-20
-
-
Gaddam, D.1
Stevens, N.2
Hollien, J.3
-
10
-
-
68049110633
-
IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates
-
Han D, Lerner AG, Vande Walle L, Upton J P, Xu W, Hagen A, Backes BJ, Oakes SA, Papa FR (2009). IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. Cell 138, 562-575.
-
(2009)
Cell
, vol.138
, pp. 562-575
-
-
Han, D.1
Lerner, A.G.2
Vande Walle, L.3
Upton, J.P.4
Xu, W.5
Hagen, A.6
Backes, B.J.7
Oakes, S.A.8
Papa, F.R.9
-
11
-
-
0033634654
-
Regulated translation initiation controls stress-induced gene expression in mammalian cells
-
Harding H P, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M, Ron D (2000). Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 6, 1099-1108.
-
(2000)
Mol Cell
, vol.6
, pp. 1099-1108
-
-
Harding, H.P.1
Novoa, I.2
Zhang, Y.3
Zeng, H.4
Wek, R.5
Schapira, M.6
Ron, D.7
-
12
-
-
0033590451
-
Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase
-
Harding H P, Zhang Y, Ron D (1999). Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397, 271-274.
-
(1999)
Nature
, vol.397
, pp. 271-274
-
-
Harding, H.P.1
Zhang, Y.2
Ron, D.3
-
13
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
Harding H P, Zhang Y, Zeng H, Novoa I, Lu PD, Calfon M, Sadri N, Yun C, Popko B, Paules R, et al. (2003). An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol Cell 11, 619-633.
-
(2003)
Mol Cell
, vol.11
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
Sadri, N.7
Yun, C.8
Popko, B.9
Paules, R.10
-
14
-
-
68549092781
-
Regulated Ire1-dependent decay of messenger RNAs in mammalian cells
-
Hollien J, Lin JH, Li H, Stevens N, Walter P, Weissman JS (2009). Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol 186, 323-331.
-
(2009)
J Cell Biol
, vol.186
, pp. 323-331
-
-
Hollien, J.1
Lin, J.H.2
Li, H.3
Stevens, N.4
Walter, P.5
Weissman, J.S.6
-
15
-
-
33745893809
-
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
-
Hollien J, Weissman JS (2006). Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 313, 104-107.
-
(2006)
Science
, vol.313
, pp. 104-107
-
-
Hollien, J.1
Weissman, J.S.2
-
16
-
-
84856856011
-
IRE1alpha activation protects mice against acetaminophen-induced hepatotoxicity
-
Hur KY, So JS, Ruda V, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Iwawaki T, Glimcher LH, Lee AH (2012). IRE1alpha activation protects mice against acetaminophen-induced hepatotoxicity. J Exp Med 209, 307-318.
-
(2012)
J Exp Med
, vol.209
, pp. 307-318
-
-
Hur, K.Y.1
So, J.S.2
Ruda, V.3
Frank-Kamenetsky, M.4
Fitzgerald, K.5
Koteliansky, V.6
Iwawaki, T.7
Glimcher, L.H.8
Lee, A.H.9
-
17
-
-
0001201488
-
Establishment of a clonal osteogenic cell line from newborn mouse calvaria
-
Kodama H, Amagai Y, Ando H, Yamamoto S (1981). Establishment of a clonal osteogenic cell line from newborn mouse calvaria. Jpn J Oral Biol 899-901.
-
(1981)
Jpn J Oral Biol
, pp. 899-901
-
-
Kodama, H.1
Amagai, Y.2
Ando, H.3
Yamamoto, S.4
-
18
-
-
0035200990
-
Ribosomal pausing at a frameshifter RNA pseudoknot is sensitive to reading phase but shows little correlation with frameshift effciency
-
Kontos H, Napthine S, Brierley I (2001). Ribosomal pausing at a frameshifter RNA pseudoknot is sensitive to reading phase but shows little correlation with frameshift effciency. Mol Cell Biol 21, 8657-8670.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 8657-8670
-
-
Kontos, H.1
Napthine, S.2
Brierley, I.3
-
19
-
-
0036837864
-
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha
-
Koumenis C, Naczki C, Koritzinsky M, Rastani S, Diehl A, Sonenberg N, Koromilas A, Wouters BG (2002). Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha. Mol Cell Biol 22, 7405-7416.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7405-7416
-
-
Koumenis, C.1
Naczki, C.2
Koritzinsky, M.3
Rastani, S.4
Diehl, A.5
Sonenberg, N.6
Koromilas, A.7
Wouters, B.G.8
-
20
-
-
77958016968
-
Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering
-
Li H, Korennykh AV, Behrman SL, Walter P (2010). Mammalian endoplasmic reticulum stress sensor IRE1 signals by dynamic clustering. Proc Natl Acad Sci USA 107, 16113-16118.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 16113-16118
-
-
Li, H.1
Korennykh, A.V.2
Behrman, S.L.3
Walter, P.4
-
21
-
-
0041315834
-
Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress
-
Ma Y, Hendershot LM (2003). Delineation of a negative feedback regulatory loop that controls protein translation during endoplasmic reticulum stress. J Biol Chem 278, 34864-34873.
-
(2003)
J Biol Chem
, vol.278
, pp. 34864-34873
-
-
Ma, Y.1
Hendershot, L.M.2
-
22
-
-
77951252041
-
Plasma cell differentiation initiates a limited ER stress response by specifcally suppressing the PERK-dependent branch of the unfolded protein response
-
Ma Y, Shimizu Y, Mann MJ, Jin Y, Hendershot LM (2010). Plasma cell differentiation initiates a limited ER stress response by specifcally suppressing the PERK-dependent branch of the unfolded protein response. Cell Stress Chaperones 15, 281-293.
-
(2010)
Cell Stress Chaperones
, vol.15
, pp. 281-293
-
-
Ma, Y.1
Shimizu, Y.2
Mann, M.J.3
Jin, Y.4
Hendershot, L.M.5
-
23
-
-
84863115336
-
A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation
-
Majumder M, Huang C, Snider MD, Komar AA, Tanaka J, Kaufman RJ, Krokowski D, Hatzoglou M (2012). A novel feedback loop regulates the response to endoplasmic reticulum stress via the cooperation of cytoplasmic splicing and mRNA translation. Mol Cell Biol 32, 992-1003.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 992-1003
-
-
Majumder, M.1
Huang, C.2
Snider, M.D.3
Komar, A.A.4
Tanaka, J.5
Kaufman, R.J.6
Krokowski, D.7
Hatzoglou, M.8
-
24
-
-
84870166429
-
The unfolded protein response in secretory cell function
-
Moore KA, Hollien J (2012). The unfolded protein response in secretory cell function. Annu Rev Genet 46, 165-183.
-
(2012)
Annu Rev Genet
, vol.46
, pp. 165-183
-
-
Moore, K.A.1
Hollien, J.2
-
25
-
-
84884278268
-
Regulation of sumo mRNA during endoplasmic reticulum stress
-
Moore KA, Plant JJ, Gaddam D, Craft J, Hollien J (2013). Regulation of sumo mRNA during endoplasmic reticulum stress. PLoS One 8, e75723.
-
(2013)
PLoS One
, vol.8
, pp. e75723
-
-
Moore, K.A.1
Plant, J.J.2
Gaddam, D.3
Craft, J.4
Hollien, J.5
-
26
-
-
84866869135
-
Rab GTPase mediated procollagen traffcking in ascorbic acid stimulated osteoblasts
-
Nabavi N, Pustylnik S, Harrison RE (2012). Rab GTPase mediated procollagen traffcking in ascorbic acid stimulated osteoblasts. PLoS One 7, e46265.
-
(2012)
PLoS One
, vol.7
, pp. e46265
-
-
Nabavi, N.1
Pustylnik, S.2
Harrison, R.E.3
-
27
-
-
0035947778
-
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha
-
Novoa I, Zeng H, Harding H P, Ron D (2001). Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J Cell Biol 153, 1011-1022.
-
(2001)
J Cell Biol
, vol.153
, pp. 1011-1022
-
-
Novoa, I.1
Zeng, H.2
Harding, H.P.3
Ron, D.4
-
28
-
-
84888136634
-
The intimate relationships of mRNA decay and translation
-
Roy B, Jacobson A (2013). The intimate relationships of mRNA decay and translation. Trends Genet 29, 691-699.
-
(2013)
Trends Genet
, vol.29
, pp. 691-699
-
-
Roy, B.1
Jacobson, A.2
-
29
-
-
84881530677
-
Pharmacological brake-release of mRNA translation enhances cognitive memory
-
Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK, Wilson C, et al. (2013). Pharmacological brake-release of mRNA translation enhances cognitive memory. Elife 2, e00498.
-
(2013)
Elife
, vol.2
, pp. e00498
-
-
Sidrauski, C.1
Acosta-Alvear, D.2
Khoutorsky, A.3
Vedantham, P.4
Hearn, B.R.5
Li, H.6
Gamache, K.7
Gallagher, C.M.8
Ang, K.K.9
Wilson, C.10
-
30
-
-
84867038186
-
Silencing of lipid metabolism genes through IRE1alpha-mediated mRNA decay lowers plasma lipids in mice
-
So JS, Hur KY, Tarrio M, Ruda V, Frank-Kamenetsky M, Fitzgerald K, Koteliansky V, Lichtman AH, Iwawaki T, Glimcher LH, Lee AH (2012). Silencing of lipid metabolism genes through IRE1alpha-mediated mRNA decay lowers plasma lipids in mice. Cell Metab 16, 487-499.
-
(2012)
Cell Metab
, vol.16
, pp. 487-499
-
-
So, J.S.1
Hur, K.Y.2
Tarrio, M.3
Ruda, V.4
Frank-Kamenetsky, M.5
Fitzgerald, K.6
Koteliansky, V.7
Lichtman, A.H.8
Iwawaki, T.9
Glimcher, L.H.10
Lee, A.H.11
-
31
-
-
42949117285
-
Analysis of mRNA partitioning between the cytosol and endoplasmic reticulum compartments of mammalian cells
-
Stephens SB, Dodd RD, Lerner RS, Pyhtila BM, Nicchitta CV (2008). Analysis of mRNA partitioning between the cytosol and endoplasmic reticulum compartments of mammalian cells. Methods Mol Biol 419, 197-214.
-
(2008)
Methods Mol Biol
, vol.419
, pp. 197-214
-
-
Stephens, S.B.1
Dodd, R.D.2
Lerner, R.S.3
Pyhtila, B.M.4
Nicchitta, C.V.5
-
32
-
-
0034724520
-
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
-
Travers KJ, Patil CK, Wodicka L, Lockhart DJ, Weissman JS, Walter P (2000). Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation. Cell 101, 249-258.
-
(2000)
Cell
, vol.101
, pp. 249-258
-
-
Travers, K.J.1
Patil, C.K.2
Wodicka, L.3
Lockhart, D.J.4
Weissman, J.S.5
Walter, P.6
-
33
-
-
3843117589
-
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
-
Vattem KM, Wek RC (2004). Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells. Proc Natl Acad Sci USA 101, 11269-11274.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 11269-11274
-
-
Vattem, K.M.1
Wek, R.C.2
-
34
-
-
82255173966
-
The unfolded protein response: From stress pathway to homeostatic regulation
-
Walter P, Ron D (2011). The unfolded protein response: from stress pathway to homeostatic regulation. Science 334, 1081-1086.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
35
-
-
84896301208
-
Quality control: Is there quality control of localized mRNAs?
-
Walters R, Parker R (2014). Quality control: is there quality control of localized mRNAs? J Cell Biol 204, 863-868.
-
(2014)
J Cell Biol
, vol.204
, pp. 863-868
-
-
Walters, R.1
Parker, R.2
-
36
-
-
0035966269
-
XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor
-
Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K (2001). XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107, 881-891.
-
(2001)
Cell
, vol.107
, pp. 881-891
-
-
Yoshida, H.1
Matsui, T.2
Yamamoto, A.3
Okada, T.4
Mori, K.5
|