Blood-brain barrier function and biomarkers of central nervous system injury in rickettsial versus other neurological infections in Laos

American Journal of Tropical Medicine and Hygiene

Volumn 93, Issue 2, 2015, Pages 232-237

  Dittrich, Sabine ^b   Sunyakumthorn, Piyanate ^b   Rattanavong, Sayaphet ^b   Phetsouvanh, Rattanaphone ^b   Panyanivong, Phonepasith ^b   Sengduangphachanh, Amphonsavanh ^b   Phouminh, Phonelavanh ^b   Anantatat, Tippawan ^b   Chanthongthip, Anisone ^b   Lee, Sue J ^b   Dubot Péres, Audrey ^b   Day, Nicholas P J ^b   Paris, Daniel H ^b   Newton, Paul N ^b   Turner, Gareth D H ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

^b MAHOSOT HOSPITAL   (Laos)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; BIOLOGICAL MARKER; GLIAL FIBRILLARY ACIDIC PROTEIN; LACTIC ACID; NEURON SPECIFIC ENOLASE; TAU PROTEIN;

ADULT; ARTICLE; ASTROCYTE; BACTERIAL MENINGITIS; BLOOD BRAIN BARRIER; CENTRAL NERVOUS SYSTEM INFECTION; CEREBROSPINAL FLUID; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN CELL; JAPANESE ENCEPHALITIS; LAOS; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MENINGITIS; MORTALITY; NEISSERIACEAE INFECTION; ORIENTIA TSUTSUGAMUSHI; RICKETTSIA; RICKETTSIACEAE INFECTION; RICKETTSIOSIS; SCRUB TYPHUS; SEIZURE; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PNEUMONIA; TUBERCULOSIS; TUBERCULOSIS MENINGITIS; ADOLESCENT; CENTRAL NERVOUS SYSTEM; CHILD; ENCEPHALITIS, JAPANESE; ISOLATION AND PURIFICATION; JAPANESE ENCEPHALITIS VIRUS; METABOLISM; MICROBIOLOGY; MIDDLE AGED; NERVOUS SYSTEM DISEASES; PATHOLOGY; RICKETTSIA INFECTIONS; TUBERCULOSIS, MENINGEAL; VIROLOGY; YOUNG ADULT;

BACTERIA (MICROORGANISMS); JAPANESE ENCEPHALITIS VIRUS; MURINAE; ORIENTIA TSUTSUGAMUSHI; RICKETTSIA;

ADOLESCENT; ADULT; BIOMARKERS; BLOOD-BRAIN BARRIER; CENTRAL NERVOUS SYSTEM; CHILD; ENCEPHALITIS VIRUS, JAPANESE; ENCEPHALITIS, JAPANESE; FEMALE; HUMANS; LAOS; MALE; MIDDLE AGED; NERVOUS SYSTEM DISEASES; ORIENTIA TSUTSUGAMUSHI; RICKETTSIA; RICKETTSIA INFECTIONS; SCRUB TYPHUS; TUBERCULOSIS, MENINGEAL; YOUNG ADULT;

EID: 84939244128     PISSN: 00029637     EISSN: 14761645     Source Type: Journal    
DOI: 10.4269/ajtmh.15-0119     Document Type: Article

References (16)

1. Ramakrishnan M, Ulland AJ, Steinhardt LC, Moisi JC, Were F, Levine OS, 2009. Sequelae Due to Bacterial Meningitis among African Children: A Systematic Literature Review. BMCMed 7: 47
2. Taylor WR, Nguyen K, Nguyen D, Nguyen H, Horby P, Nguyen HL, Lien T, Tran G, Tran N, Nguyen HM, Nguyen T, Nguyen HH, Nguyen T, Tran G, Farrar J, de Jong M, Schultsz C, Tran H, Nguyen D, Vu B, Le H, Dao T, Nguyen T, Wertheim H, 2012. The spectrum of central nervous system infections in an adult referral hospital in Hanoi, Vietnam. PLoS One 7: e42099.
3. Dittrich S, Rattanavong S, Lee SJ, Panyanivong P, Craig SB, Tulsiani SM, Blacksell SD, Dance DA, Dubot-Peres A, SengduangphachanhA, Phoumin P, Paris DH, Newton PN, 2015. Orientia, Rickettsia, and Leptospira pathogens as causes of CNS infections in Laos: a prospective study. Lancet Glob Health 3: e104-e112.
4. Nilsson K, Wallmenius K, Hartwig S, Norlander T, Pahlson C, 2013. Bell's palsy and sudden deafness associated with Rickettsia spp. infection in Sweden. A retrospective and prospective serological survey including PCR findings. Eur J Neurol 21: 206-214.
5. Sayen JJ, Pond HS, Forrester JS, Wood FC, 1946. Scrub typhus in Assam and Burma; a clinical study of 616 cases. Medicine (Baltimore) 25: 155-214.
6. Pai H, Sohn S, Seong Y, Kee S, Chang WH, Choe KW, 1997. Central nervous system involvement in patients with scrub typhus. Clin Infect Dis 24: 436-440.
7. Kim DM, Chung JH, Yun NR, Kim SW, Lee JY, Han MA, Lee YB, 2013. Scrub typhus meningitis or meningoencephalitis. Am J Trop Med Hyg 89: 1206-1211.
8. Viswanathan S, Muthu V, Iqbal N, Remalayam B, George T, 2013. Scrub typhus meningitis in south India-a retrospective study. PLoS One 8: e66595.
9. Moore CE, Blacksell SD, Taojaikong T, Jarman RG, Gibbons RV, Lee SJ, Chansamouth V, Thongpaseuth S, Mayxay M, Newton PN, 2012. A prospective assessment of the accuracy of commercial IgM ELISAs in diagnosis of Japanese encephalitis virus infections in patients with suspected central nervous system infections in Laos. Am J Trop Med Hyg 87: 171-178.
10. Moron CG, Popov VL, Feng HM, Wear D, Walker DH, 2001. Identification of the target cells of Orientia tsutsugamushi in human cases of scrub typhus. Mod Pathol 14: 752-759.
11. Brown HC, Chau TT, Mai NT, Day NP, Sinh DX, White NJ, Hien TT, Farrar J, Turner GD, 2000. Blood-brain barrier function in cerebral malaria and CNS infections in Vietnam. Neurology 55: 104-111.
12. Peluso MJ, Meyerhoff DJ, Price RW, Peterson J, Lee E, Young AC, Walter R, Fuchs D, Brew BJ, Cinque P, Robertson K, Hagberg L, Zetterberg H, Gisslen M, Spudich S, 2013. Cerebrospinal fluid and neuroimaging biomarker abnormalities suggest early neurological injury in a subset of individuals during primary HIV infection. J Infect Dis 207: 1703-1712.
13. Moureau G, Ninove L, Izri A, Cook S, De Lamballerie X, Charrel RN, 2010. Flavivirus RNA in phlebotomine sandflies. Vector Borne Zoonotic Dis 10: 195-197.
14. Petzold A, 2007. CSF biomarkers for improved prognostic accuracy in acute CNS disease. Neurol Res 29: 691-708.
15. BrounsR,DeVilB,CrasP,DeSurgelooseD,MariënP,DeDeyn PP, 2010. Neurobiochemicalmarkers of brain damage in cerebrospinal fluid of acute ischemic stroke patients. Clin Chem 56: 451-458.
16. Rosso SM, van Herpen E, Pijnenburg YA, Schoonenboom NS, Scheltens P, Heutink P, van Swieten JC, 2003. Total tau and phosphorylated tau 181 levels in the cerebrospinal fluid of patients with frontotemporal dementia due to p301l and g272v tau mutations. Arch Neurol 60: 1209-1213.