Cerebrospinal fluid and neuroimaging biomarker abnormalities suggest early neurological injury in a subset of individuals during primary HIV infection

Journal of Infectious Diseases

Volumn 207, Issue 11, 2013, Pages 1703-1712

  Peluso, Michael J ^a   Meyerhoff, Dieter J ^b   Price, Richard W ^c   Peterson, Julia ^c   Lee, Evelyn ^c   Young, Andrew C ^a   Walter, Rudy ^b   Fuchs, Dietmar ^d   Brew, Bruce J ^e   Cinque, Paola ^f   Robertson, Kevin ^g   Hagberg, Lars ^h   Zetterberg, Henrik ^h   Gisslén, Magnus ^h   Spudich, Serena ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Radiology and Biomedical Imaging ^*  (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^e UNIVERSITY OF NEW SOUTH WALES   (Australia)

^f SAN RAFFAELE HOSPITAL   (Italy)

^g UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

biomarkers; HIV AIDS; magnetic resonance spectroscopy; neurofilament light chain; neurological damage; primary HIV infection

Indexed keywords

ALBUMIN; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; BIOLOGICAL MARKER; CREATININE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLUTAMIC ACID; MONOCYTE CHEMOTACTIC PROTEIN 1; N ACETYLASPARTIC ACID; NEOPTERIN; NEUROFILAMENT PROTEIN; P TAU PROTEIN; PROTEIN; T TAU PROTEIN; TAU PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ANTERIOR CINGULATE; ARTICLE; CD4+ T LYMPHOCYTE; CEREBROSPINAL FLUID; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; EARLY DIAGNOSIS; FEMALE; FRONTAL CORTEX; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; INTERMETHOD COMPARISON; LEUKOCYTE; MAJOR CLINICAL STUDY; MALE; METABOLITE; NERVOUS SYSTEM INFLAMMATION; NEUROIMAGING; NEUROLOGIC DISEASE; NEUROPSYCHOLOGY; PARIETAL CORTEX; PATHOGENESIS; PRIMARY INFECTION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; WHITE MATTER;

EID: 84877252688     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jit088     Document Type: Article

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