Total tau and phosphorylated tau 181 levels in the cerebrospinal fluid of patients with frontotemporal dementia due to P301L and G272V tau mutations

Archives of Neurology

Volumn 60, Issue 9, 2003, Pages 1209-1213

  Rosso, Sonia M ^a   Van Herpen, Esther ^a   Pijnenburg, Yolande A L ^b   Schoonenboom, Niki S M ^b   Scheltens, Philip ^b   Heutink, Peter ^a   Van Swieten, John C ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN [1-42]; TAU PROTEIN; UNCLASSIFIED DRUG;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN REGION; CEREBROSPINAL FLUID ANALYSIS; CHROMOSOME 17; CLINICAL EXAMINATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FRONTOTEMPORAL DEMENTIA; GENE MUTATION; HUMAN; LUMBAR PUNCTURE; MAJOR CLINICAL STUDY; MALE; NEUROLOGIC EXAMINATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TAUOPATHY;

AGED; ATROPHY; CHROMOSOMES, HUMAN, PAIR 17; DEMENTIA; DNA MUTATIONAL ANALYSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FRONTAL LOBE; GENE EXPRESSION; HUMANS; MALE; MIDDLE AGED; MUTATION, MISSENSE; PHOSPHORYLATION; POINT MUTATION; PROTEIN-SERINE-THREONINE KINASES; TAU PROTEINS; TEMPORAL LOBE;

EID: 0042922481     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.60.9.1209     Document Type: Article

References (24)

1. Neary D, Snowden JS, Gustafson L, et al. Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology. 1998;51:1546-1554.
2. Heutink P. Untangling tau-related dementia. Hum Mol Genet. 2000;9:979-986.
3. Spillantini MG, van SJ, Goedert M. Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Neurogenetics. 2000;2:193-205.
4. Cooper PN, Jackson M, Lennox G, Lowe J, Mann DM. Tau, ubiquitin, and alpha B-crystallin immunohistochemistry define the principal causes of degenerative frontotemporal dementia. Arch Neurol. 1995;52:1011-1015.
5. Riemenschneider M, Wagenpfeil S, Diehl J, et al. Tau and Abeta42 protein in CSF of patients with frontotemporal degeneration. Neurology 2002;58:1622-1628.
6. Fabre SF, Forsell C, Viitanen M, et al. Clinic-based cases with frontotemporal dementia show increased cerebrospinal fluid tau and high apolipoprotein E epsilon4 frequency, but no tau gene mutations. Exp Neurol. 2001;168:413-418.
7. Spillantini MG, Crowther RA, Kamphorst W, Heutink P, van Swieten JC. Tau pathology in two Dutch families with mutations in the microtubule-binding region of tau. Am J Pathol. 1998;153:1359-1363.
8. Rizzu P, van Swieten J, Joosse M, et al. High prevalence of mutations in the microtubule-associated protein tau in a population study of frontotemporal dementia in the Netherlands. Am J Hum Genet. 1999;64:414-421.
9. McKhann GM, Albert MS, Grossman M, Miller B, Dickson D, Trojanowski J. Clinical and pathological diagnosis of frontotemporal dementia: report of the Work Group on Frontotemporal Dementia and Pick's Disease. Arch Neurol. 2001;58:1803-1809.
10. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34:939-944.
11. Vandermeeren M, Mercken M, Vanmechelen E, et al. Detection of t proteins in normal and Alzheimer's disease cerebrospinal fluid with a sensitive sandwich enzyme-linked immunosorbent assay. J Neurochem. 1993;61:1828-1834.
12. Vanmechelen E, Vanderstichele H, Davidsson P, et al. Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardization. Neurosci Lett. 2000;285:49-52.
13. Vanderstichele H, Van Kerschaver E, Hesse C, et al. Standardization of measurement of β-amyloid (1-42) in cerebrospinal fluid and plasma. Amyloid. 2000;7:245-258.
14. Lopez OL, Litvan I, Catt KE, et al. Accuracy of four clinical diagnostic criteria for the diagnosis of neurodegenerative dementias. Neurology. 1999;53:1292-1299.
15. Kapaki E, Kilidireas K, Paraskevas GP, Michalopoulou M, Patsouris E. Highly increased CSF tau protein and decreased beta-amyloid (1-42) in sporadic CJD: a discrimination from Alzheimer's disease? J Neurol Neurosurg Psychiatry. 2001;71:401-403.
16. Hesse C, Rosengren L, Andreasen N, et al. Transient increase in total tau but not phospho-tau in human cerebrospinal fluid after acute stroke. Neurosci Lett. 2001;297:187-190.
17. Itoh N, Arai H, Urakami K, et al. Large-scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimer's disease. Ann Neurol. 2001;50:150-156.
18. Sjogren M, Davidsson P, Tullberg M, et al. Both total and phosphorylated tau are increased in Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2001;70:624-630.
19. Buerger K, Zinkowski R, Teipel SJ, et al. Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231. Arch Neurol. 2002;59:1267-1272.
20. Endoh R, Ogawara M, Iwatsubo T, Nakano I, Mori H. Lack of the carboxyl terminal sequence of tau in ghost tangles of Alzheimer's disease. Brain Res. 1993;601:164-172.
21. Van Swieten JC, Stevens M, Rosso SM, et al. Phenotypic variation in Hereditary Frontotemporal Dementia with Tau mutations. Ann Neurol. 1999;64:617-626.
22. Adamec E, Mohan P, Vonsattel JP, Nixon RA. Calpain activation in neurodegenerative diseases: confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2. Acta Neuropathol (Berl). 2002;104:92-104.
23. Hasegawa M, Smith MJ, Goedert M. Tau proteins with FTDP-17 mutations have a reduced ability to promote microtubule assembly. FEBS Lett. 1998;437:207-210.
24. D'Souza I, Poorkaj P, Hong M, et al. Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements. Proc Natl Acad Sci U S A. 1999;96:5598-5603.