-
1
-
-
0034782842
-
The frequency of common progenitors for adipocytes and osteoblasts and of committed and restricted adipocyte and osteoblast progenitors in fetal rat calvaria cell populations
-
PMID:11697794
-
Bellows CG, Heersche JN. The frequency of common progenitors for adipocytes and osteoblasts and of committed and restricted adipocyte and osteoblast progenitors in fetal rat calvaria cell populations. J Bone Miner Res. 2001; 16:1983-1993. PMID:11697794
-
(2001)
J Bone Miner Res
, vol.16
, pp. 1983-1993
-
-
Bellows, C.G.1
Heersche, J.N.2
-
2
-
-
84255200563
-
Building strong bones: Molecular regulation of the osteoblast lineage
-
PMID:22189423
-
Long F. Building strong bones: molecular regulation of the osteoblast lineage. Nat Rev Mol Cell Biol. 2011; 13:27-38. doi:10.1038/nrm3254 PMID:22189423
-
(2011)
Nat Rev Mol Cell Biol
, vol.13
, pp. 27-38
-
-
Long, F.1
-
3
-
-
84859778293
-
MTOR signaling in growth control and disease
-
PMID:22500797
-
Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell. 2012; 149:274-293. doi:10.1016/j.cell.2012.03.017 PMID:22500797
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
4
-
-
78649348967
-
Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress
-
PMID:20965424
-
Sengupta S, Peterson TR, Sabatini DM. Regulation of the mTOR complex 1 pathway by nutrients, growth factors, and stress. Mol Cell. 2010; 40:310-322. doi:10.1016/j.molcel.2010.09.026 PMID:20965424
-
(2010)
Mol Cell
, vol.40
, pp. 310-322
-
-
Sengupta, S.1
Peterson, T.R.2
Sabatini, D.M.3
-
5
-
-
84903955288
-
MTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis
-
PMID:24948603
-
Chen J, Long F. mTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis. Development. 2014; 141:2848-2854. doi:10.1242/dev.108811 PMID:24948603
-
(2014)
Development
, vol.141
, pp. 2848-2854
-
-
Chen, J.1
Long, F.2
-
6
-
-
84921710835
-
MTORC2 signaling promotes skeletal growth and bone formation in mice
-
PMID:25196701
-
Chen J, Holguin N, Shi Y, Silva MJ, Long F. mTORC2 signaling promotes skeletal growth and bone formation in mice. J Bone Miner Res. 2015; 30:369-78. doi:10.1002/jbmr.2348 PMID:25196701
-
(2015)
J Bone Miner Res
, vol.30
, pp. 369-378
-
-
Chen, J.1
Holguin, N.2
Shi, Y.3
Silva, M.J.4
Long, F.5
-
7
-
-
84896717086
-
WNT7B promotes bone formation in part through mTORC1
-
PMID:24497849
-
Chen J, Tu X, Esen E, Joeng KS, Lin C, Arbeit JM, et al. WNT7B promotes bone formation in part through mTORC1. PLoS Genet. 2014; 10 (1):e1004145. doi:10.1371/journal.pgen.1004145 PMID:24497849
-
(2014)
PLoS Genet
, vol.10
, Issue.1
, pp. e1004145
-
-
Chen, J.1
Tu, X.2
Esen, E.3
Joeng, K.S.4
Lin, C.5
Arbeit, J.M.6
-
8
-
-
33846513349
-
Rapamycin as an inhibitor of osteogenic differentiation in bone marrow-derived mesenchymal stem cells
-
PMID:17260122
-
Isomoto S, Hattori K, Ohgushi H, Nakajima H, Tanaka Y, Takakura Y. Rapamycin as an inhibitor of osteogenic differentiation in bone marrow-derived mesenchymal stem cells. J Orthop Sci. 2007; 12:83-88. PMID:17260122
-
(2007)
J Orthop Sci
, vol.12
, pp. 83-88
-
-
Isomoto, S.1
Hattori, K.2
Ohgushi, H.3
Nakajima, H.4
Tanaka, Y.5
Takakura, Y.6
-
9
-
-
0037445980
-
Inhibition of phosphatidylinositol 3-kinase and p70S6 kinase blocks osteogenic protein- 1 induction of alkaline phosphatase activity in fetal rat calvaria cells
-
PMID:12647306
-
Shoba LN, Lee JC. Inhibition of phosphatidylinositol 3-kinase and p70S6 kinase blocks osteogenic protein- 1 induction of alkaline phosphatase activity in fetal rat calvaria cells. J Cell Biochem. 2003; 88:1247-1255. PMID:12647306
-
(2003)
J Cell Biochem
, vol.88
, pp. 1247-1255
-
-
Shoba, L.N.1
Lee, J.C.2
-
10
-
-
38649110155
-
Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cells
-
PMID:17516572
-
Singha UK, Jiang Y, Yu S, Luo M, Lu Y, Zhang J, et al. Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cells. J Cell Biochem. 2008; 103:434-446. PMID:17516572
-
(2008)
J Cell Biochem
, vol.103
, pp. 434-446
-
-
Singha, U.K.1
Jiang, Y.2
Yu, S.3
Luo, M.4
Lu, Y.5
Zhang, J.6
-
11
-
-
84863726841
-
Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells
-
PMID:22729283
-
Xian L, Wu X, Pang L, Lou M, Rosen CJ, Qiu T, et al. Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells. Nat Med. 2012; 18:1095-1101. doi:10.1038/nm.2793 PMID:22729283
-
(2012)
Nat Med
, vol.18
, pp. 1095-1101
-
-
Xian, L.1
Wu, X.2
Pang, L.3
Lou, M.4
Rosen, C.J.5
Qiu, T.6
-
12
-
-
84921413874
-
MTOR inhibition rescues osteopenia in mice with systemic sclerosis
-
PMID:25534817
-
Chen C, Akiyama K, Wang D, Xu X, Li B, Moshaverinia A, et al. mTOR inhibition rescues osteopenia in mice with systemic sclerosis. J Exp Med. 2015; 212:73-91. doi:10.1084/jem.20140643 PMID:25534817
-
(2015)
J Exp Med
, vol.212
, pp. 73-91
-
-
Chen, C.1
Akiyama, K.2
Wang, D.3
Xu, X.4
Li, B.5
Moshaverinia, A.6
-
13
-
-
77950603770
-
Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway
-
PMID:19642865
-
Lee KW, Yook JY, Son MY, Kim MJ, Koo DB, Han YM, et al. Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway. Stem Cells Dev. 2010; 19:557-568. doi:10.1089/scd.2009.0147 PMID:19642865
-
(2010)
Stem Cells Dev
, vol.19
, pp. 557-568
-
-
Lee, K.W.1
Yook, J.Y.2
Son, M.Y.3
Kim, M.J.4
Koo, D.B.5
Han, Y.M.6
-
14
-
-
77957686102
-
NVP-BEZ235, a dual pan class i PI3 kinase and mTOR inhibitor, promotes osteogenic differentiation in human mesenchymal stromal cells
-
PMID:20499346
-
Martin SK, Fitter S, Bong LF, Drew JJ, Gronthos S, Shepherd PR, et al. NVP-BEZ235, a dual pan class I PI3 kinase and mTOR inhibitor, promotes osteogenic differentiation in human mesenchymal stromal cells. J Bone Miner Res. 2010; 25:2126-2137. doi:10.1002/jbmr.114 PMID:20499346
-
(2010)
J Bone Miner Res
, vol.25
, pp. 2126-2137
-
-
Martin, S.K.1
Fitter, S.2
Bong, L.F.3
Drew, J.J.4
Gronthos, S.5
Shepherd, P.R.6
-
15
-
-
0032504527
-
Osteoblastic differentiation is enhanced by rapamycin in rat osteoblast-like osteosarcoma (ROS 17/2.8) cells
-
PMID:9705862
-
Ogawa T, Tokuda M, Tomizawa K, Matsui H, Itano T, Konishi R, et al. Osteoblastic differentiation is enhanced by rapamycin in rat osteoblast-like osteosarcoma (ROS 17/2.8) cells. Biochem Biophys Res Commun. 1998; 249:226-230. PMID:9705862
-
(1998)
Biochem Biophys Res Commun
, vol.249
, pp. 226-230
-
-
Ogawa, T.1
Tokuda, M.2
Tomizawa, K.3
Matsui, H.4
Itano, T.5
Konishi, R.6
-
16
-
-
33748768971
-
Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors
-
PMID:16854976
-
Rodda SJ, McMahon AP. Distinct roles for Hedgehog and canonical Wnt signaling in specification, differentiation and maintenance of osteoblast progenitors. Development. 2006; 133:3231-3244. PMID:16854976
-
(2006)
Development
, vol.133
, pp. 3231-3244
-
-
Rodda, S.J.1
McMahon, A.P.2
-
17
-
-
78650848337
-
MTORC1 controls fasting-induced ketogenesis and its modulation by ageing
-
PMID:21179166
-
Sengupta S, Peterson TR, Laplante M, Oh S, Sabatini DM. mTORC1 controls fasting-induced ketogenesis and its modulation by ageing. Nature. 2010; 468:1100-1104. doi:10.1038/nature09584 PMID:21179166
-
(2010)
Nature
, vol.468
, pp. 1100-1104
-
-
Sengupta, S.1
Peterson, T.R.2
Laplante, M.3
Oh, S.4
Sabatini, D.M.5
-
18
-
-
77954756294
-
Guidelines for assessment of bone microstructure in rodents using micro-computed tomography
-
PMID:20533309
-
Bouxsein ML, Boyd SK, Christiansen BA, Guldberg RE, Jepsen KJ, Muller R. Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. J Bone Miner Res. 2010; 25:1468-1486. doi:10.1002/jbmr.141 PMID:20533309
-
(2010)
J Bone Miner Res
, vol.25
, pp. 1468-1486
-
-
Bouxsein, M.L.1
Boyd, S.K.2
Christiansen, B.A.3
Guldberg, R.E.4
Jepsen, K.J.5
Muller, R.6
-
19
-
-
84886819890
-
Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation
-
PMID:23633228
-
Liu F, Fang F, Yuan H, Yang D, Chen Y, Williams L, et al. Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation. J Bone Miner Res. 2013; 28:2414-2430. doi:10.1002/jbmr.1971 PMID:23633228
-
(2013)
J Bone Miner Res
, vol.28
, pp. 2414-2430
-
-
Liu, F.1
Fang, F.2
Yuan, H.3
Yang, D.4
Chen, Y.5
Williams, L.6
-
20
-
-
84879065741
-
Suppression of autophagy in osteocytes mimics skeletal aging
-
PMID:23645674
-
Onal M, Piemontese M, Xiong J, Wang Y, Han L, Ye S, et al. Suppression of autophagy in osteocytes mimics skeletal aging. J Biol Chem. 2013; 288:17432-17440. doi:10.1074/jbc.M112.444190 PMID:23645674
-
(2013)
J Biol Chem
, vol.288
, pp. 17432-17440
-
-
Onal, M.1
Piemontese, M.2
Xiong, J.3
Wang, Y.4
Han, L.5
Ye, S.6
-
21
-
-
3242888703
-
LC3 GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
-
PMID:15169837
-
Kabeya Y, Mizushima N, Yamamoto A, Oshitani-Okamoto S, Ohsumi Y, Yoshimori T. LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation. J Cell Sci. 2004; 117:2805-2812. PMID:15169837
-
(2004)
J Cell Sci
, vol.117
, pp. 2805-2812
-
-
Kabeya, Y.1
Mizushima, N.2
Yamamoto, A.3
Oshitani-Okamoto, S.4
Ohsumi, Y.5
Yoshimori, T.6
-
22
-
-
0032983542
-
Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential
-
PMID:10352097
-
Wang D, Christensen K, Chawla K, Xiao G, Krebsbach PH, Franceschi RT. Isolation and characterization of MC3T3-E1 preosteoblast subclones with distinct in vitro and in vivo differentiation/mineralization potential. J Bone Miner Res. 1999; 14:893-903. PMID:10352097
-
(1999)
J Bone Miner Res
, vol.14
, pp. 893-903
-
-
Wang, D.1
Christensen, K.2
Chawla, K.3
Xiao, G.4
Krebsbach, P.H.5
Franceschi, R.T.6
-
23
-
-
41549139755
-
Mesenchymal stem cells: Revisiting history, concepts, and assays
-
PMID:18397751
-
Bianco P, Robey PG, Simmons PJ. Mesenchymal stem cells: revisiting history, concepts, and assays. Cell Stem Cell. 2008; 2:313-319. doi:10.1016/j.stem.2008.03.002 PMID:18397751
-
(2008)
Cell Stem Cell
, vol.2
, pp. 313-319
-
-
Bianco, P.1
Robey, P.G.2
Simmons, P.J.3
-
24
-
-
84898621357
-
Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice
-
PMID: 24454809
-
Chen J, Shi Y, Regan J, Karuppaiah K, Ornitz DM, Long F. Osx-Cre targets multiple cell types besides osteoblast lineage in postnatal mice. PLoS One. 2014; 9(1):e85161. doi:10.1371/journal.pone. 0085161 PMID:24454809
-
(2014)
PLoS One
, vol.9
, Issue.1
, pp. e85161
-
-
Chen, J.1
Shi, Y.2
Regan, J.3
Karuppaiah, K.4
Ornitz, D.M.5
Long, F.6
-
25
-
-
84877579844
-
WNT-LRP5 Signaling Induces Warburg Effect through mTORC2 Activation during Osteoblast Differentiation
-
PMID:23623748
-
Esen E, Chen J, Karner CM, Okunade AL, Patterson BW, Long F. WNT-LRP5 Signaling Induces Warburg Effect through mTORC2 Activation during Osteoblast Differentiation.Cell Metab. 2013; 17:745-55. doi:10.1016/j.cmet.2013.03.017 PMID:23623748
-
(2013)
Cell Metab
, vol.17
, pp. 745-755
-
-
Esen, E.1
Chen, J.2
Karner, C.M.3
Okunade, A.L.4
Patterson, B.W.5
Long, F.6
-
26
-
-
84925673012
-
The differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation
-
PMID:25537496
-
Martin SK, Fitter S, Dutta AK, Matthews MP, Walkley CR, Hall MN, et al. The differential roles of mTORC1 and mTORC2 in mesenchymal stem cell differentiation. Stem Cells. 2015; 33(4): 1359-65. doi:10.1002/stem.1931 PMID:25537496
-
(2015)
Stem Cells
, vol.33
, Issue.4
, pp. 1359-1365
-
-
Martin, S.K.1
Fitter, S.2
Dutta, A.K.3
Matthews, M.P.4
Walkley, C.R.5
Hall, M.N.6
-
27
-
-
84890920876
-
MTORC2 regulates mechanically induced cytoskeletal reorganization and lineage selection in marrow derived mesenchymal stem cells
-
PMID:23821483
-
Sen B, Xie Z, Case N, Thompson WR, Uzer G, Styner M, et al. mTORC2 regulates mechanically induced cytoskeletal reorganization and lineage selection in marrow derived mesenchymal stem cells. J Bone Miner Res. 2014; 29(1):78-89. doi:10.1002/jbmr.2031 PMID:23821483
-
(2014)
J Bone Miner Res
, vol.29
, Issue.1
, pp. 78-89
-
-
Sen, B.1
Xie, Z.2
Case, N.3
Thompson, W.R.4
Uzer, G.5
Styner, M.6
|