Synthesis and in Vitro Anticancer Activity of the First Class of Dual Inhibitors of REV-ERBβ and Autophagy

Journal of Medicinal Chemistry

Volumn 58, Issue 15, 2015, Pages 5900-5915

  Torrente, Esther ^a   Parodi, Chiara ^a   Ercolani, Luisa ^a   De Mei, Claudia ^a   Ferrari, Alessio ^a   Scarpelli, Rita ^a   Grimaldi, Benedetto ^a  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CELL NUCLEUS RECEPTOR; CHLOROQUINE; PROTEIN INHIBITOR; PROTEIN REV ERB BETA; REV ERB BETA INHIBITOR; UNCLASSIFIED DRUG; CELL RECEPTOR; NR1D2 PROTEIN, HUMAN; REPRESSOR PROTEIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; BREAST CANCER; CANCER CELL; CONTROLLED STUDY; CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY; STRUCTURE ACTIVITY RELATION; ANTAGONISTS AND INHIBITORS; BREAST NEOPLASMS; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; FEMALE; PATHOLOGY; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; AUTOPHAGY; BREAST NEOPLASMS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; IN VITRO TECHNIQUES; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REPRESSOR PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84939173295     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.5b00511     Document Type: Article

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