메뉴 건너뛰기




Volumn 10, Issue 6, 2015, Pages

In vitro anti-tumor effects of statins on head and neck squamous cell carcinoma: A systematic review

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; AMLODIPINE BESYLATE; ATORVASTATIN; CASPASE 3; CETUXIMAB; CISPLATIN; CYCLIN D1; CYCLIN D2; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; FLUOROURACIL; GEFITINIB; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; GUANOSINE TRIPHOSPHATASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INITIATION FACTOR 4E BINDING PROTEIN 1; LIVER KINASE B1; MEVALONIC ACID; MEVINOLIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONENSIN; PHOSPHOTRANSFERASE; PRAVASTATIN; PROTEIN KINASE B; PROTEIN RHOC; SALUBRINAL; SIMVASTATIN; STAT3 PROTEIN; UNCLASSIFIED DRUG; UNINDEXED DRUG; ANTINEOPLASTIC AGENT;

EID: 84939172623     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0130476     Document Type: Review
Times cited : (38)

References (37)
  • 1
    • 77955114517 scopus 로고    scopus 로고
    • A historical perspective on the discovery of statins
    • PMID: 20467214
    • Endo A. A historical perspective on the discovery of statins. Proc Jpn Acad Ser B Phys Bio Sci 2010; 86:484-93. PMID: 20467214.
    • (2010) Proc Jpn Acad Ser B Phys Bio Sci , vol.86 , pp. 484-493
    • Endo, A.1
  • 2
    • 0026448725 scopus 로고
    • The discovery special article and development of HMG-CoA reductase inhibitors
    • Endo A. The discovery special article and development of HMG-CoA reductase inhibitors. J Lip Res 1992; 33:1569-82.
    • (1992) J Lip Res , vol.33 , pp. 1569-1582
    • Endo, A.1
  • 3
    • 0026607503 scopus 로고
    • Cholesterol inhibition, cancer, and chemotherapy
    • PMID: 1349377
    • Buchwald H. Cholesterol inhibition, cancer, and chemotherapy. Lancet 1992; 339(8802):1154-06. PMID: 1349377.
    • (1992) Lancet , vol.339 , Issue.8802 , pp. 1154-1206
    • Buchwald, H.1
  • 4
    • 0028929401 scopus 로고
    • Pharmacology of competitive inhibitors of HMG-CoA reductase
    • PMID: 7784310
    • Corsini A, Maggi FM, Catapano AL. Pharmacology of competitive inhibitors of HMG-CoA reductase. Pharmacol Res 1995; 31:9-27. PMID: 7784310.
    • (1995) Pharmacol Res , vol.31 , pp. 9-27
    • Corsini, A.1    Maggi, F.M.2    Catapano, A.L.3
  • 5
    • 0037233011 scopus 로고    scopus 로고
    • The statins as anticancer agents
    • PMID: 12538446
    • Chan KK, Oza AM, Siu LL. The statins as anticancer agents. Clin Cancer Res 2003; 9:10-19. PMID: 12538446.
    • (2003) Clin Cancer Res , vol.9 , pp. 10-19
    • Chan, K.K.1    Oza, A.M.2    Siu, L.L.3
  • 6
    • 84887419206 scopus 로고    scopus 로고
    • Lovastatininduced apoptosis is mediated by activating transcription factor 3 and enhanced in combination with salubrinal
    • PMID: 23824972
    • Niknejad N, Gorn-Hondermann I, Ma L, Zahr S, Johnson-Obeseki S, Corsten M, et al. Lovastatininduced apoptosis is mediated by activating transcription factor 3 and enhanced in combination with salubrinal. Int J Cancer 2014; 134:268-79. doi:10.1002/ijc.28369 PMID: 23824972.
    • (2014) Int J Cancer , vol.134 , pp. 268-279
    • Niknejad, N.1    Gorn-Hondermann, I.2    Ma, L.3    Zahr, S.4    Johnson-Obeseki, S.5    Corsten, M.6
  • 7
    • 84880059155 scopus 로고    scopus 로고
    • Atorvastatin inhibits RhoC function and limits head and neck cancer metastasis
    • PMID: 23648017
    • Islam M, Sharma S, Kumar B, Teknos TN. Atorvastatin inhibits RhoC function and limits head and neck cancer metastasis. Oral Oncol 2013; 49:778-86. doi:10.1016/j.oraloncology.2013.04.003 PMID: 23648017.
    • (2013) Oral Oncol , vol.49 , pp. 778-786
    • Islam, M.1    Sharma, S.2    Kumar, B.3    Teknos, T.N.4
  • 8
    • 84867021493 scopus 로고    scopus 로고
    • Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells
    • PMID: 23029387
    • Ma L, Niknejad N, Gorn-Hondermann I, Dayekh K, Dimitroulakos J. Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells. Plos One 2012; 7: E46055. doi:10.1371/journal.pone.0046055 PMID: 23029387.
    • (2012) Plos One , vol.7 , pp. e46055
    • Ma, L.1    Niknejad, N.2    Gorn-Hondermann, I.3    Dayekh, K.4    Dimitroulakos, J.5
  • 9
    • 0036020213 scopus 로고    scopus 로고
    • Microarray and biochemical analysis of lovastatin-induced apoptosis of squamous cell carcinomas
    • PMID: 12082550
    • Dimitroulakos J, Marhin WH, Tokunaga J, Irish J, Gullane P, Penn LZ, et al. Microarray and biochemical analysis of lovastatin-induced apoptosis of squamous cell carcinomas. Neoplasia 2002; 4:337-46. PMID: 12082550.
    • (2002) Neoplasia , vol.4 , pp. 337-346
    • Dimitroulakos, J.1    Marhin, W.H.2    Tokunaga, J.3    Irish, J.4    Gullane, P.5    Penn, L.Z.6
  • 10
    • 20044366735 scopus 로고    scopus 로고
    • A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix
    • PMID: 15737556
    • Knox JJ, Siu LL, Chen E, Dimitroulakos J, Kamel-Reid S, Moore MJ, et al. A Phase I trial of prolonged administration of lovastatin in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or of the cervix. Eur J Cancer 2005; 41:523-30. PMID: 15737556.
    • (2005) Eur J Cancer , vol.41 , pp. 523-530
    • Knox, J.J.1    Siu, L.L.2    Chen, E.3    Dimitroulakos, J.4    Kamel-Reid, S.5    Moore, M.J.6
  • 11
    • 16844384956 scopus 로고    scopus 로고
    • Targeting the mevalonate pathway inhibits the function of the epidermal growth factor receptor
    • PMID: 15788691
    • Mantha AJ, Hanson JE, Goss G, Lagarde AE, Lorimer IA, Dimitroulakos J. Targeting the mevalonate pathway inhibits the function of the epidermal growth factor receptor. Clin Cancer Res 2005; 11:2398- 07. PMID: 15788691.
    • (2005) Clin Cancer Res , vol.11 , pp. 2398-2407
    • Mantha, A.J.1    Hanson, J.E.2    Goss, G.3    Lagarde, A.E.4    Lorimer, I.A.5    Dimitroulakos, J.6
  • 12
    • 80555154901 scopus 로고    scopus 로고
    • Targeting mTOR for the treatment of AML, New agents and new directions
    • PMID: 21680954
    • Altman JK, Sassano A, Platanias LC. Targeting mTOR for the treatment of AML. New agents and new directions. Oncotarget 2011; 2:510-07. PMID: 21680954.
    • (2011) Oncotarget , vol.2 , pp. 510-607
    • Altman, J.K.1    Sassano, A.2    Platanias, L.C.3
  • 13
    • 67349186933 scopus 로고    scopus 로고
    • Global epidemiology of oral and oropharyngeal cancer
    • PMID: 18804401
    • Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol 2009; 45:309- 16. doi:10.1016/j.oraloncology.2008.06.002 PMID: 18804401.
    • (2009) Oral Oncol , vol.45 , pp. 309-316
    • Warnakulasuriya, S.1
  • 14
    • 0034726387 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and the risk of cancer: A nested case-control study
    • PMID: 10927735
    • Blais L, Desgagne A, LeLorier J. 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and the risk of cancer: A nested case-control study. Arch Intern Med 2000; 160: 2363-68. PMID: 10927735.
    • (2000) Arch Intern Med , vol.160 , pp. 2363-2368
    • Blais, L.1    Desgagne, A.2    LeLorier, J.3
  • 15
    • 2942754163 scopus 로고    scopus 로고
    • The risk of cancer in users of statins
    • PMID: 15197200
    • Graaf M, Beiderbeck A, Egberts A, et al. The risk of cancer in users of statins. J Clin Oncol 2004; 22: 2388-94. PMID: 15197200.
    • (2004) J Clin Oncol , vol.22 , pp. 2388-2394
    • Graaf, M.1    Beiderbeck, A.2    Egberts, A.3
  • 16
    • 69149107165 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • The PRISMA Group., PMID: 19622511
    • Moher D, Liberati A, Tetzlaff J, Altman DG; The PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. Ann Intern Med 2009; 151:264-69. PMID: 19622511.
    • (2009) Ann Intern Med , vol.151 , pp. 264-269
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 18
    • 79951952372 scopus 로고    scopus 로고
    • GRADE guidelines: 1. Introduction- GRADE evidence profiles and summary of findings tables
    • PMID: 21195583
    • Guyatt G, Oxman AD, Akl EA, Kunz R, Vist G, Brozek J, et al. GRADE guidelines: 1. Introduction- GRADE evidence profiles and summary of findings tables. J Clin Epidemiol 2011; 64:383-94. doi:10.1016/j.jclinepi.2010.04.026 PMID: 21195583.
    • (2011) J Clin Epidemiol , vol.64 , pp. 383-394
    • Guyatt, G.1    Oxman, A.D.2    Akl, E.A.3    Kunz, R.4    Vist, G.5    Brozek, J.6
  • 19
    • 84884886205 scopus 로고    scopus 로고
    • Interventions to improve chronic cyclosporine. A nephrotoxicity through inhibiting renal cell apoptosis: A systematic review
    • Engl
    • Xiao Z, Li C, Shan J, Luo L, Feng L, Lu J, et al. Interventions to improve chronic cyclosporine. A nephrotoxicity through inhibiting renal cell apoptosis: A systematic review. Chinese Med J (Engl) 2013; 126:3767-74.
    • (2013) Chinese Med J , vol.126 , pp. 3767-3774
    • Xiao, Z.1    Li, C.2    Shan, J.3    Luo, L.4    Feng, L.5    Lu, J.6
  • 20
    • 0035132669 scopus 로고    scopus 로고
    • Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: Therapeutic implications
    • PMID: 11205904
    • Dimitroulakos J, Ye LY, Benzaquen M, Moore MJ, Kamel-Reid S, Freedman MH, et al. Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: Therapeutic implications. Clin Cancer Res 2001; 7:158-67. PMID: 11205904.
    • (2001) Clin Cancer Res , vol.7 , pp. 158-167
    • Dimitroulakos, J.1    Ye, L.Y.2    Benzaquen, M.3    Moore, M.J.4    Kamel-Reid, S.5    Freedman, M.H.6
  • 21
    • 0344011564 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-targeted therapy potentiates lovastatin-induced apoptosis in head and neck squamous cell carcinoma cells
    • PMID: 12942316
    • Mantha AJ, McFee KE, Niknejad N, Goss G, Lorimer IA, Dimitroulakos J. Epidermal growth factor receptor-targeted therapy potentiates lovastatin-induced apoptosis in head and neck squamous cell carcinoma cells. J Cancer Res Clin Oncol 2003; 129:631-41. PMID: 12942316.
    • (2003) J Cancer Res Clin Oncol , vol.129 , pp. 631-641
    • Mantha, A.J.1    McFee, K.E.2    Niknejad, N.3    Goss, G.4    Lorimer, I.A.5    Dimitroulakos, J.6
  • 22
    • 35648985077 scopus 로고    scopus 로고
    • Activation of the integrated stress response regulates lovastatin- induced apoptosis
    • PMID: 17699156
    • Niknejad N, Morley M, Dimitroulakos J. Activation of the integrated stress response regulates lovastatin- induced apoptosis. J Biol Chem 2007; 282:29748-56. PMID: 17699156.
    • (2007) J Biol Chem , vol.282 , pp. 29748-29756
    • Niknejad, N.1    Morley, M.2    Dimitroulakos, J.3
  • 23
    • 84919393755 scopus 로고    scopus 로고
    • Monensin inhibits epidermal growth factor receptor trafficking and activation: Synergistic cytotoxicity in combination with EGFR inhibitors
    • PMID: 25189541
    • Dayekh K, Johnson-Obaseki, Corsten M, Villeneuve P, Sekhon H, Weberpals J et al. Monensin inhibits epidermal growth factor receptor trafficking and activation: Synergistic cytotoxicity in combination with EGFR inhibitors. Mol Cancer Ther 2014; 13:2559-71. doi:10.1158/1535-7163.MCT-13-1086 PMID: 25189541.
    • (2014) Mol Cancer Ther , vol.13 , pp. 2559-2571
    • Dayekh, K.1    Johnson-Obaseki2    Corsten, M.3    Villeneuve, P.4    Sekhon, H.5    Weberpals, J.6
  • 24
    • 27144481039 scopus 로고    scopus 로고
    • In nasopharyngeal carcinoma cells, Epstein-Barr virus LMP1 interacts with galectin 9 in membrane raft elements resistant to simvastatin
    • PMID: 16227255
    • Pioche-Durieu C, Keryer C, Souquöure S, Bosq J, Faigle W, Loew D, et al. In nasopharyngeal carcinoma cells, Epstein-Barr virus LMP1 interacts with galectin 9 in membrane raft elements resistant to simvastatin. J Virol 2005; 79:13326-37. PMID: 16227255.
    • (2005) J Virol , vol.79 , pp. 13326-13337
    • Pioche-Durieu, C.1    Keryer, C.2    Souquöure, S.3    Bosq, J.4    Faigle, W.5    Loew, D.6
  • 25
    • 38149075979 scopus 로고    scopus 로고
    • Effects of lovastatin alone or combined with irradiation on tumor cells in vitro and in vivo
    • PMID: 18188523
    • Gabrýs D, Dörfler A, Yaromina A, Hessel F, Krause M, Oertel R, et al. Effects of lovastatin alone or combined with irradiation on tumor cells in vitro and in vivo. Strahlenther Onkol 2008; 184:48-53. doi:10.1007/s00066-008-1805-7 PMID: 18188523.
    • (2008) Strahlenther Onkol , vol.184 , pp. 48-53
    • Gabrýs, D.1    Dörfler, A.2    Yaromina, A.3    Hessel, F.4    Krause, M.5    Oertel, R.6
  • 26
    • 84907315508 scopus 로고    scopus 로고
    • Simvastatin enhances the effects of radiotherapy and cetuximab on a cell line (FaDu) derived from a squamous cell carcinoma of head and neck
    • PMID: 25171892
    • Llobet L, Baro M, Mesia R, Balart J. Simvastatin enhances the effects of radiotherapy and cetuximab on a cell line (FaDu) derived from a squamous cell carcinoma of head and neck. Transl Oncol 2014; 7:513-22. doi:10.1016/j.tranon.2014.02.008 PMID: 25171892.
    • (2014) Transl Oncol , vol.7 , pp. 513-522
    • Llobet, L.1    Baro, M.2    Mesia, R.3    Balart, J.4
  • 27
    • 34247868147 scopus 로고    scopus 로고
    • Simvastatin inactivates beta1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells
    • PMID: 17428261
    • Takeda I, Maruya S, Shirasaki T, Mizukami H, Takahata T, Myers JN, et al. Simvastatin inactivates beta1-integrin and extracellular signal-related kinase signaling and inhibits cell proliferation in head and neck squamous cell carcinoma cells. Cancer Sci 2007; 98:890-9. PMID: 17428261.
    • (2007) Cancer Sci , vol.98 , pp. 890-899
    • Takeda, I.1    Maruya, S.2    Shirasaki, T.3    Mizukami, H.4    Takahata, T.5    Myers, J.N.6
  • 28
    • 84861141736 scopus 로고    scopus 로고
    • Novel effects of statins in enhancing efficacy of chemotherapy in vitro in nasopharyngeal carcinoma
    • PMID: 22287433
    • Wang W, Le W, Cho DY, Hwang PH, Upadhyay D. Novel effects of statins in enhancing efficacy of chemotherapy in vitro in nasopharyngeal carcinoma. Int Forum Allergy Rhinol 2011; 1:284-9. doi:10.1002/alr.20039 PMID: 22287433.
    • (2011) Int Forum Allergy Rhinol , vol.1 , pp. 284-289
    • Wang, W.1    Le, W.2    Cho, D.Y.3    Hwang, P.H.4    Upadhyay, D.5
  • 29
    • 84863587948 scopus 로고    scopus 로고
    • Targeted therapy in head and neck cancer
    • PMID: 22373581
    • Kundu SK, Nestor M. Targeted therapy in head and neck cancer. Tumour Biol 2012; 33:707-21. doi:10.1007/s13277-012-0350-2 PMID: 22373581.
    • (2012) Tumour Biol , vol.33 , pp. 707-721
    • Kundu, S.K.1    Nestor, M.2
  • 30
    • 71649109232 scopus 로고    scopus 로고
    • Causes of oral cancer- An appraisal of controversies
    • PMID: 19946320
    • Warnakulasuriya S. Causes of oral cancer- An appraisal of controversies. Br Dent J 2009; 207:471-5. doi:10.1038/sj.bdj.2009.1009 PMID: 19946320.
    • (2009) Br Dent J , vol.207 , pp. 471-475
    • Warnakulasuriya, S.1
  • 31
    • 67349118132 scopus 로고    scopus 로고
    • Lifestyle risk factors for oral cancer
    • PMID: 18674956
    • Petti S. Lifestyle risk factors for oral cancer. Oral Oncol 2009; 45:340-50. doi:10.1016/j.oraloncology.2008.05.018 PMID: 18674956.
    • (2009) Oral Oncol , vol.45 , pp. 340-350
    • Petti, S.1
  • 32
    • 79953107664 scopus 로고    scopus 로고
    • Evaluation of human papillomavirus testing for squamous cell carcinoma of the tonsil in clinical practice
    • PMID: 21345874
    • Thavaraj S, Stokes A, Guerra E, Bible J, Halligan E, Long A, et al. Evaluation of human papillomavirus testing for squamous cell carcinoma of the tonsil in clinical practice. J Clin Pathol 2011; 64:308-12. doi:10.1136/jcp.2010.088450 PMID: 21345874.
    • (2011) J Clin Pathol , vol.64 , pp. 308-312
    • Thavaraj, S.1    Stokes, A.2    Guerra, E.3    Bible, J.4    Halligan, E.5    Long, A.6
  • 33
    • 33646886144 scopus 로고    scopus 로고
    • Advances in the treatment of locally advanced non-nasopharyngeal squamous cell carcinoma of the head and neck region
    • PMID: 16645225
    • Psyrri A, Fountzilas G. Advances in the treatment of locally advanced non-nasopharyngeal squamous cell carcinoma of the head and neck region. Med Oncol 2006; 23:1-15. PMID: 16645225.
    • (2006) Med Oncol , vol.23 , pp. 1-15
    • Psyrri, A.1    Fountzilas, G.2
  • 34
    • 84921730580 scopus 로고    scopus 로고
    • Current treatment of head and neck squamous cell cancer
    • PMID: 25053506
    • Belcher R, Hayes K, Fedewa S, Chen AY. Current treatment of head and neck squamous cell cancer. J Surg Oncol 2014; 110:551-74. doi:10.1002/jso.23724 PMID: 25053506.
    • (2014) J Surg Oncol , vol.110 , pp. 551-574
    • Belcher, R.1    Hayes, K.2    Fedewa, S.3    Chen, A.Y.4
  • 36
    • 0030953045 scopus 로고    scopus 로고
    • Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors similarities and differences
    • PMID: 9160173
    • Lennernäs H, Fager G. Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences. Clin Pharmacokinet 1997; 32:403-25. PMID: 9160173.
    • (1997) Clin Pharmacokinet , vol.32 , pp. 403-425
    • Lennernäs, H.1    Fager, G.2
  • 37
    • 20144384882 scopus 로고    scopus 로고
    • Lost in trascription: P21 repression, mechanisms and consequences
    • PMID: 15899785
    • Gartel AL, Radhaskrishnan SK. Lost in trascription: P21 repression, mechanisms and consequences. Cancer Res 2005; 65:3980-5. PMID: 15899785.
    • (2005) Cancer Res , vol.65 , pp. 3980-3985
    • Gartel, A.L.1    Radhaskrishnan, S.K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.