Oral administration of pH-sensitive curcumin-loaded microparticles for ulcerative colitis therapy

Colloids and Surfaces B: Biointerfaces

Volumn 135, Issue , 2015, Pages 379-385

  Xiao, Bo ^a,b   Si, Xiaoying ^a   Zhang, Mingzhen ^b   Merlin, Didier ^b,c  

^a SOUTHWEST UNIVERSITY   (China)

^b GEORGIA STATE UNIVERSITY   (United States)

^c ATLANTA VA MEDICAL CENTER   (United States)

Author keywords

Curcumin; Microparticle; Oral administration; PH Sensitivity; Ulcerative colitis

Indexed keywords

BIOMATERIALS; DISEASES; DRUG PRODUCTS; EFFICIENCY; EMULSIFICATION; PARTICLE SIZE;

CURCUMIN; MICRO PARTICLES; ORAL ADMINISTRATION; PH SENSITIVITY; ULCERATIVE COLITIS;

PH SENSORS;

CURCUMIN; EUDRAGIT; POLYGLACTIN; DELAYED RELEASE FORMULATION; DEXTRAN SULFATE; DRUG CARRIER; LACTIC ACID; METHYLMETHACRYLATE-METHACRYLIC ACID COPOLYMER; NANOPARTICLE; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXIDASE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; POLYMETHACRYLIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL EFFECTIVENESS; COLON; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; IN VIVO STUDY; INCUBATION TIME; MALE; MOUSE; NANOENCAPSULATION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; ORGAN WEIGHT; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PHYSICAL PARAMETERS; PRIORITY JOURNAL; SPLEEN; STAINING; ULCERATIVE COLITIS; WEIGHT REDUCTION; ANIMAL; CHEMICALLY INDUCED; CHEMISTRY; COLITIS, ULCERATIVE; DELAYED RELEASE FORMULATION; DRUG EFFECTS; FEMALE; METABOLISM; ORAL DRUG ADMINISTRATION; ORGAN SIZE; PATHOLOGY;

ADMINISTRATION, ORAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; COLITIS, ULCERATIVE; CURCUMIN; DELAYED-ACTION PREPARATIONS; DEXTRAN SULFATE; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; HYDROGEN-ION CONCENTRATION; LACTIC ACID; MICE; NANOPARTICLES; ORGAN SIZE; PARTICLE SIZE; PEROXIDASE; POLYGLYCOLIC ACID; POLYMETHACRYLIC ACIDS;

EID: 84939127091     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2015.07.081     Document Type: Article

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