Water-soluble benzodiazepine prodrug/enzyme combinations for intranasal rescue therapies

Epilepsy and Behavior

Volumn 49, Issue , 2015, Pages 347-350

  Siegel, Ronald A ^a,b   Kapoor, Mamta ^a   Cheryala, Narsihmulu ^c   Georg, Gunda I ^c   Cloyd, James C ^a,c  

^a UNIVERSITY OF MINNESOTA   (United States)

^b University of Minnesota   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Avizafone; Benzodiazepine; Diazepam; Intranasal; Midazolam; Prodrug; Prodrug enzyme

Indexed keywords

AVIZAFONE; MIDAZOLAM PRODRUG; PRODRUG; PROTEINASE; UNCLASSIFIED DRUG; WATER; ANTICONVULSIVE AGENT; BENZODIAZEPINE DERIVATIVE; DIAZEPAM; ENZYME; MIDAZOLAM; PEPTIDE HYDROLASE;

ARTICLE; ASPERGILLUS ORYZAE; DRUG CONCENTRATION; DRUG METABOLISM; DRUG RELEASE; DRUG SOLUBILITY; DRUG STRUCTURE; DRUG TRANSPORT; IN VITRO STUDY; INTRANASAL DRUG ADMINISTRATION; MDCK CELL LINE; ANIMAL; CHEMISTRY; DOG; ENZYMOLOGY; SOLUBILITY; STATUS EPILEPTICUS;

ADMINISTRATION, INTRANASAL; ANIMALS; ANTICONVULSANTS; ASPERGILLUS ORYZAE; BENZODIAZEPINES; DIAZEPAM; DOGS; ENZYMES; MADIN DARBY CANINE KIDNEY CELLS; MIDAZOLAM; PEPTIDE HYDROLASES; PRODRUGS; SOLUBILITY; STATUS EPILEPTICUS;

EID: 84938996113     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2015.05.004     Document Type: Article

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