Preparation of lorazepam-loaded microemulsions for intranasal delivery and its pharmacokinetics

Pharmazie

Volumn 64, Issue 10, 2009, Pages 642-647

  Yao, J ^a   Hou, L ^a   Zhou, J P ^a   Zhang, Z Q ^a   Sun, L ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; BENZYL ALCOHOL; CREMOPHOR; DIETHYLENE GLYCOL MONOETHYL ETHER; DRUG VEHICLE; LORAZEPAM; MACROGOL 400; OIL; POLYSORBATE 80; SURFACTANT; WATER; DRUG DERIVATIVE; ETHYLENE GLYCOL DERIVATIVE; GLYCEROL; HYPNOTIC SEDATIVE AGENT;

ANALYTICAL EQUIPMENT; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG HALF LIFE; DRUG SOLUBILITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICROEMULSION; NONHUMAN; PARTICLE SIZE; RABBIT; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; CHEMISTRY; DOSE RESPONSE; EMULSION; INTRAMUSCULAR DRUG ADMINISTRATION; INTRANASAL DRUG ADMINISTRATION; SOLUBILITY; VEHICLES;

ADMINISTRATION, INTRANASAL; ANIMALS; AREA UNDER CURVE; DOSE-RESPONSE RELATIONSHIP, DRUG; EMULSIONS; ETHYLENE GLYCOLS; GLYCEROL; HYPNOTICS AND SEDATIVES; INJECTIONS, INTRAMUSCULAR; LORAZEPAM; PARTICLE SIZE; RABBITS; SOLUBILITY; SURFACE-ACTIVE AGENTS; VEHICLES;

EID: 74949121236     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2009.9082     Document Type: Article

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