-
1
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell. 2006;126:663-76.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
2
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell. 2007;131:861-72.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
-
3
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu J, Vodyanik MA, Smuga-Otto K, et al. Induced pluripotent stem cell lines derived from human somatic cells. Science. 2007;318:1917-20.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
-
4
-
-
77956278519
-
Promotion of direct reprogramming by transformation-deficient Myc
-
Nakagawa M, Takizawa N, Narita M, Ichisaka T, Yamanaka S. Promotion of direct reprogramming by transformation-deficient Myc. Proc Natl Acad Sci U S A. 2010;107:14152-7.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 14152-14157
-
-
Nakagawa, M.1
Takizawa, N.2
Narita, M.3
Ichisaka, T.4
Yamanaka, S.5
-
5
-
-
79955634826
-
A more efficient method to generate integration-free human iPS cells
-
Okita K, Matsumura Y, Sato Y, et al. A more efficient method to generate integration-free human iPS cells. Nat Methods. 2011;8:409-12.
-
(2011)
Nat Methods
, vol.8
, pp. 409-412
-
-
Okita, K.1
Matsumura, Y.2
Sato, Y.3
-
6
-
-
79958292714
-
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
-
Maekawa M, Yamaguchi K, Nakamura T, et al. Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1. Nature. 2011;474:225-9.
-
(2011)
Nature
, vol.474
, pp. 225-229
-
-
Maekawa, M.1
Yamaguchi, K.2
Nakamura, T.3
-
7
-
-
80655123674
-
Glis1, a unique pro-reprogramming factor, may facilitate clinical applications of iPSC technology
-
Maekawa M, Yamanaka S. Glis1, a unique pro-reprogramming factor, may facilitate clinical applications of iPSC technology. Cell Cycle. 2011;10:3613-4.
-
(2011)
Cell Cycle
, vol.10
, pp. 3613-3614
-
-
Maekawa, M.1
Yamanaka, S.2
-
8
-
-
84925341709
-
A comparison of non-integrating reprogramming methods
-
Schlaeger TM, Daheron L, Brickler TR, et al. A comparison of non-integrating reprogramming methods. Nat Biotechnol. 2015;33:58-63.
-
(2015)
Nat Biotechnol
, vol.33
, pp. 58-63
-
-
Schlaeger, T.M.1
Daheron, L.2
Brickler, T.R.3
-
9
-
-
84920747084
-
Inhibition of pluripotency networks by the rb tumor suppressor restricts reprogramming and tumorigenesis
-
Kareta MS, Gorges LL, Hafeez S, et al. Inhibition of pluripotency networks by the rb tumor suppressor restricts reprogramming and tumorigenesis. Cell Stem Cell. 2015;16:39-50.
-
(2015)
Cell Stem Cell
, vol.16
, pp. 39-50
-
-
Kareta, M.S.1
Gorges, L.L.2
Hafeez, S.3
-
10
-
-
69349098834
-
Stem cells: The promises and perils of p53
-
Krizhanovsky V, Lowe SW. Stem cells: the promises and perils of p53. Nature. 2009;460:1085-6.
-
(2009)
Nature
, vol.460
, pp. 1085-1086
-
-
Krizhanovsky, V.1
Lowe, S.W.2
-
11
-
-
84878600256
-
Inhibition of PTEN tumor suppressor promotes the generation of induced pluripotent stem cells
-
Liao J, Marumoto T, Yamaguchi S, et al. Inhibition of PTEN tumor suppressor promotes the generation of induced pluripotent stem cells. Mol Ther. 2013;21:1242-50.
-
(2013)
Mol Ther
, vol.21
, pp. 1242-1250
-
-
Liao, J.1
Marumoto, T.2
Yamaguchi, S.3
-
12
-
-
77951878056
-
Induced pluripotent stem cells and senescence: Learning the biology to improve the technology
-
Banito A, Gil J. Induced pluripotent stem cells and senescence: learning the biology to improve the technology. EMBO Rep. 2010;11:353-9.
-
(2010)
EMBO Rep
, vol.11
, pp. 353-359
-
-
Banito, A.1
Gil, J.2
-
13
-
-
70349093119
-
Senescence impairs successful reprogramming to pluripotent stem cells
-
Banito A, Rashid ST, Acosta JC, et al. Senescence impairs successful reprogramming to pluripotent stem cells. Genes Dev. 2009;23:2134-9.
-
(2009)
Genes Dev
, vol.23
, pp. 2134-2139
-
-
Banito, A.1
Rashid, S.T.2
Acosta, J.C.3
-
14
-
-
84860517655
-
iPSCs from cancer cells: Challenges and opportunities
-
Ramos-Mejia V, Fraga MF, Menendez P. iPSCs from cancer cells: challenges and opportunities. Trends Mol Med. 2012;18:245-7.
-
(2012)
Trends Mol Med
, vol.18
, pp. 245-247
-
-
Ramos-Mejia, V.1
Fraga, M.F.2
Menendez, P.3
-
15
-
-
52949125268
-
Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state
-
Lin SL, Chang DC, Chang-Lin S, et al. Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like state. RNA. 2008;14:2115-24.
-
(2008)
RNA
, vol.14
, pp. 2115-2124
-
-
Lin, S.L.1
Chang, D.C.2
Chang-Lin, S.3
-
16
-
-
70350380887
-
Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells
-
Utikal J, Maherali N, Kulalert W, Hochedlinger K. Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells. J Cell Sci. 2009;122:3502-10.
-
(2009)
J Cell Sci
, vol.122
, pp. 3502-3510
-
-
Utikal, J.1
Maherali, N.2
Kulalert, W.3
Hochedlinger, K.4
-
17
-
-
76249133692
-
Defined factors induce reprogramming of gastrointestinal cancer cells
-
Miyoshi N, Ishii H, Nagai K, et al. Defined factors induce reprogramming of gastrointestinal cancer cells. Proc Natl Acad Sci U S A. 2010;107:40-5.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 40-45
-
-
Miyoshi, N.1
Ishii, H.2
Nagai, K.3
-
18
-
-
77953250105
-
Generation of iPSCs from cultured human malignant cells
-
Carette JE, Pruszak J, Varadarajan M, et al. Generation of iPSCs from cultured human malignant cells. Blood. 2010;115:4039-42.
-
(2010)
Blood
, vol.115
, pp. 4039-4042
-
-
Carette, J.E.1
Pruszak, J.2
Varadarajan, M.3
-
19
-
-
79959908506
-
HIF induces human embryonic stem cell markers in cancer cells
-
Mathieu J, Zhang Z, Zhou W, et al. HIF induces human embryonic stem cell markers in cancer cells. Cancer Res. 2011;71:4640-52.
-
(2011)
Cancer Res
, vol.71
, pp. 4640-4652
-
-
Mathieu, J.1
Zhang, Z.2
Zhou, W.3
-
20
-
-
84884849331
-
Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway
-
Corominas-Faja B, Cufi S, Oliveras-Ferraros C, et al. Nuclear reprogramming of luminal-like breast cancer cells generates Sox2-overexpressing cancer stem-like cellular states harboring transcriptional activation of the mTOR pathway. Cell Cycle. 2013;12:3109-24.
-
(2013)
Cell Cycle
, vol.12
, pp. 3109-3124
-
-
Corominas-Faja, B.1
Cufi, S.2
Oliveras-Ferraros, C.3
-
21
-
-
84875340771
-
Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner
-
Stricker SH, Feber A, Engstrom PG, et al. Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner. Genes Dev. 2013;27:654-69.
-
(2013)
Genes Dev
, vol.27
, pp. 654-669
-
-
Stricker, S.H.1
Feber, A.2
Engstrom, P.G.3
-
22
-
-
84877574727
-
Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming
-
Zhang X, Cruz FD, Terry M, Remotti F, Matushansky I. Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming. Oncogene. 2013;32(18):.e1-21.
-
(2013)
Oncogene
, vol.32
, Issue.18
, pp. e1-e21
-
-
Zhang, X.1
Cruz, F.D.2
Terry, M.3
Remotti, F.4
Matushansky, I.5
-
23
-
-
84899930229
-
Reprogramming of MLL-AF9 leukemia cells into pluripotent stem cells
-
Liu Y, Cheng H, Gao S, et al. Reprogramming of MLL-AF9 leukemia cells into pluripotent stem cells. Leukemia. 2014;28:1071-80.
-
(2014)
Leukemia
, vol.28
, pp. 1071-1080
-
-
Liu, Y.1
Cheng, H.2
Gao, S.3
-
24
-
-
79953826088
-
Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells
-
Hu K, Yu J, Suknuntha K, et al. Efficient generation of transgene-free induced pluripotent stem cells from normal and neoplastic bone marrow and cord blood mononuclear cells. Blood. 2011;117:e109-19.
-
(2011)
Blood
, vol.117
, pp. e109-e119
-
-
Hu, K.1
Yu, J.2
Suknuntha, K.3
-
25
-
-
84863505092
-
Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples
-
Kumano K, Arai S, Hosoi M, et al. Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples. Blood. 2012;119:6234-42.
-
(2012)
Blood
, vol.119
, pp. 6234-6242
-
-
Kumano, K.1
Arai, S.2
Hosoi, M.3
-
26
-
-
84881286879
-
Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia
-
Gandre-Babbe S, Paluru P, Aribeana C, et al. Patient-derived induced pluripotent stem cells recapitulate hematopoietic abnormalities of juvenile myelomonocytic leukemia. Blood. 2013;121:4925-9.
-
(2013)
Blood
, vol.121
, pp. 4925-4929
-
-
Gandre-Babbe, S.1
Paluru, P.2
Aribeana, C.3
-
27
-
-
84879798872
-
An iPSC line from human pancreatic ductal adenocarcinoma undergoes early to invasive stages of pancreatic cancer progression
-
Kim J, Hoffman JP, Alpaugh RK, et al. An iPSC line from human pancreatic ductal adenocarcinoma undergoes early to invasive stages of pancreatic cancer progression. Cell Rep. 2013;3:2088-99.
-
(2013)
Cell Rep
, vol.3
, pp. 2088-2099
-
-
Kim, J.1
Hoffman, J.P.2
Alpaugh, R.K.3
-
28
-
-
84930943281
-
Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells
-
Kotini AG, Chang CJ, Boussaad I, et al. Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells. Nat Biotechnol. 2015;33(6):646-55.
-
(2015)
Nat Biotechnol
, vol.33
, Issue.6
, pp. 646-655
-
-
Kotini, A.G.1
Chang, C.J.2
Boussaad, I.3
-
29
-
-
84927155547
-
Modeling familial cancer with induced pluripotent stem cells
-
Lee DF, Su J, Kim HS, et al. Modeling familial cancer with induced pluripotent stem cells. Cell. 2015;161:240-54.
-
(2015)
Cell
, vol.161
, pp. 240-254
-
-
Lee, D.F.1
Su, J.2
Kim, H.S.3
-
30
-
-
84938934272
-
Epigenetic reprogramming and re-differentiation of a Ewing sarcoma cell line
-
Moore JB, Loeb DM, Hong KU, et al. Epigenetic reprogramming and re-differentiation of a Ewing sarcoma cell line. Front Cell Dev Biol. 2015;3:15.
-
(2015)
Front Cell Dev Biol
, vol.3
, pp. 15
-
-
Moore, J.B.1
Loeb, D.M.2
Hong, K.U.3
-
31
-
-
3543073392
-
Reprogramming of a melanoma genome by nuclear transplantation
-
Hochedlinger K, Blelloch R, Brennan C, et al. Reprogramming of a melanoma genome by nuclear transplantation. Genes Dev. 2004;18:1875-85.
-
(2004)
Genes Dev
, vol.18
, pp. 1875-1885
-
-
Hochedlinger, K.1
Blelloch, R.2
Brennan, C.3
-
32
-
-
78149478781
-
Aberrant epigenetic landscape in cancer: How cellular identity goes awry
-
Berdasco M, Esteller M. Aberrant epigenetic landscape in cancer: how cellular identity goes awry. Dev Cell. 2010;19:698-711.
-
(2010)
Dev Cell
, vol.19
, pp. 698-711
-
-
Berdasco, M.1
Esteller, M.2
-
33
-
-
77955777216
-
Aberrant epigenetic silencing of tumor suppressor genes is reversed by direct reprogramming
-
Ron-Bigger S, Bar-Nur O, Isaac S, Bocker M, Lyko F, Eden A. Aberrant epigenetic silencing of tumor suppressor genes is reversed by direct reprogramming. Stem Cells. 2010;28:1349-54.
-
(2010)
Stem Cells
, vol.28
, pp. 1349-1354
-
-
Ron-Bigger, S.1
Bar-Nur, O.2
Isaac, S.3
Bocker, M.4
Lyko, F.5
Eden, A.6
-
34
-
-
84894109473
-
Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation
-
Ohnishi K, Semi K, Yamamoto T, et al. Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation. Cell. 2014;156:663-77.
-
(2014)
Cell
, vol.156
, pp. 663-677
-
-
Ohnishi, K.1
Semi, K.2
Yamamoto, T.3
-
35
-
-
73049104550
-
Will iPS cells enhance therapeutic applicability of cord blood cells and banking?
-
Broxmeyer HE. Will iPS cells enhance therapeutic applicability of cord blood cells and banking? Cell Stem Cell. 2010;6:21-24.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 21-24
-
-
Broxmeyer, H.E.1
-
36
-
-
84881415310
-
Disease modeling and drug screening for neurological diseases using human induced pluripotent stem cells
-
Xu XH, Zhong Z. Disease modeling and drug screening for neurological diseases using human induced pluripotent stem cells. Acta Pharmacol Sin. 2013;34:755-64.
-
(2013)
Acta Pharmacol Sin
, vol.34
, pp. 755-764
-
-
Xu, X.H.1
Zhong, Z.2
-
37
-
-
84919764228
-
Disease modeling and phenotypic drug screening for diabetic cardiomyopathy using human induced pluripotent stem cells
-
Drawnel FM, Boccardo S, Prummer M, et al. Disease modeling and phenotypic drug screening for diabetic cardiomyopathy using human induced pluripotent stem cells. Cell Rep. 2014;9:810-21.
-
(2014)
Cell Rep
, vol.9
, pp. 810-821
-
-
Drawnel, F.M.1
Boccardo, S.2
Prummer, M.3
-
38
-
-
84880026566
-
Genome editing of human pluripotent stem cells to generate human cellular disease models
-
Musunuru K. Genome editing of human pluripotent stem cells to generate human cellular disease models. Dis Model Mech. 2013;6:896-904.
-
(2013)
Dis Model Mech
, vol.6
, pp. 896-904
-
-
Musunuru, K.1
-
39
-
-
37549030199
-
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
-
Hanna J, Wernig M, Markoulaki S, et al. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science. 2007;318:1920-3.
-
(2007)
Science
, vol.318
, pp. 1920-1923
-
-
Hanna, J.1
Wernig, M.2
Markoulaki, S.3
-
40
-
-
84885115285
-
Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors
-
Doulatov S, Vo LT, Chou SS, et al. Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell. 2013;13:459-70.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 459-470
-
-
Doulatov, S.1
Vo, L.T.2
Chou, S.S.3
-
41
-
-
84929746565
-
Cellular reprogramming allows generation of autologous hematopoietic progenitors from AML patients that are devoid of patient-specific genomic aberrations
-
Salci KR, Lee JH, Laronde S, et al. Cellular reprogramming allows generation of autologous hematopoietic progenitors from AML patients that are devoid of patient-specific genomic aberrations. Stem Cells. 2015;33(6):1839-49.
-
(2015)
Stem Cells
, vol.33
, Issue.6
, pp. 1839-1849
-
-
Salci, K.R.1
Lee, J.H.2
Laronde, S.3
-
42
-
-
84900870089
-
Induced pluripotent stem cells: Challenges and opportunities for cancer immunotherapy
-
Sachamitr P, Hackett S, Fairchild PJ. Induced pluripotent stem cells: challenges and opportunities for cancer immunotherapy. Front Immunol. 2014;5:176.
-
(2014)
Front Immunol
, vol.5
, pp. 176
-
-
Sachamitr, P.1
Hackett, S.2
Fairchild, P.J.3
-
43
-
-
85015639659
-
Development of an inducible caspase-9 safety switch for pluripotent stem cell-based therapies
-
Wu C, Hong SG, Winkler T, et al. Development of an inducible caspase-9 safety switch for pluripotent stem cell-based therapies. Mol Ther Methods Clin Dev. 2014;1:14053.
-
(2014)
Mol Ther Methods Clin Dev
, vol.1
-
-
Wu, C.1
Hong, S.G.2
Winkler, T.3
-
44
-
-
80052395354
-
Safeguarding nonhuman primate iPS cells with suicide genes
-
Zhong B, Watts KL, Gori JL, et al. Safeguarding nonhuman primate iPS cells with suicide genes. Mol Ther. 2011;19:1667-75.
-
(2011)
Mol Ther
, vol.19
, pp. 1667-1675
-
-
Zhong, B.1
Watts, K.L.2
Gori, J.L.3
-
45
-
-
84904396621
-
Organogenesis in a dish: Modeling development and disease using organoid technologies
-
Lancaster MA, Knoblich JA. Organogenesis in a dish: modeling development and disease using organoid technologies. Science. 2014;345:1247125.
-
(2014)
Science
, vol.345
-
-
Lancaster, M.A.1
Knoblich, J.A.2
-
46
-
-
56749175044
-
Induction of drug metabolism: Species differences and toxicological relevance
-
Graham MJ, Lake BG. Induction of drug metabolism: species differences and toxicological relevance. Toxicology. 2008;254:184-91.
-
(2008)
Toxicology
, vol.254
, pp. 184-191
-
-
Graham, M.J.1
Lake, B.G.2
|