-
1
-
-
84870946642
-
Antimicrobial-resistant pathogens associated with healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009-2010
-
Sievert DM, Ricks P, Edwards JR et al. Antimicrobial-resistant pathogens associated with healthcare-associated infections: summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009-2010. Infect Control Hosp Epidemiol 2013;34:1-14.
-
(2013)
Infect Control Hosp Epidemiol
, vol.34
, pp. 1-14
-
-
Sievert, D.M.1
Ricks, P.2
Edwards, J.R.3
-
3
-
-
84888990813
-
National burden of invasive methicillin-resistant Staphylococcus aureus infections, United States, 2011
-
Dantes R, Mu Y, Belflower R et al. National burden of invasive methicillin-resistant Staphylococcus aureus infections, United States, 2011. JAMA Intern Med 2013;173:1970-8.
-
(2013)
JAMA Intern Med
, vol.173
, pp. 1970-1978
-
-
Dantes, R.1
Mu, Y.2
Belflower, R.3
-
4
-
-
84867332084
-
Overcoming the challenges to developing new antibiotics
-
Shales DM, Spellberg B. Overcoming the challenges to developing new antibiotics. Curr Opin Pharmacol 2012;12:522-6.
-
(2012)
Curr Opin Pharmacol
, vol.12
, pp. 522-526
-
-
Shales, D.M.1
Spellberg, B.2
-
5
-
-
84255201091
-
The oxazolidinones: Past, present, and future
-
Shaw KJ, Barbachyn MR. The oxazolidinones: past, present, and future. Ann N Y Acad Sci 2011;1241:48-70.
-
(2011)
Ann N y Acad Sci
, vol.1241
, pp. 48-70
-
-
Shaw, K.J.1
Barbachyn, M.R.2
-
6
-
-
0036073572
-
Bacterial skin infections in the elderly: Diagnosis and treatment
-
Laube S, Farrell AM. Bacterial skin infections in the elderly: diagnosis and treatment. Drugs Aging 2002;19:331-42.
-
(2002)
Drugs Aging
, vol.19
, pp. 331-342
-
-
Laube, S.1
Farrell, A.M.2
-
7
-
-
84858244397
-
In vitro activity of tedizolid (TR-700) against linezolid-resistant staphylococci
-
Rodriguez-Avial I, Culebras E, Betriu C et al. In vitro activity of tedizolid (TR-700) against linezolid-resistant staphylococci. J Antimicrob Chemother 2012;67:167-9.
-
(2012)
J Antimicrob Chemother
, vol.67
, pp. 167-169
-
-
Rodriguez-Avial, I.1
Culebras, E.2
Betriu, C.3
-
8
-
-
84858166133
-
Tedizolid (TR-701): A new oxazolidinone with enhanced potency
-
Kanafani ZA, Corey GR. Tedizolid (TR-701): a new oxazolidinone with enhanced potency. Exp Opin Invest Drugs 2012;21:515-22.
-
(2012)
Exp Opin Invest Drugs
, vol.21
, pp. 515-522
-
-
Kanafani, Z.A.1
Corey, G.R.2
-
9
-
-
67749127546
-
In vitro activity of TR-700, the active ingredient of the antibacterial prodrug TR-701, a novel oxazolidinone antibacterial agent
-
Schaadt R, Sweeney D, Shinabarger D et al. In vitro activity of TR-700, the active ingredient of the antibacterial prodrug TR-701, a novel oxazolidinone antibacterial agent. Antimicrob Agents Chemother 2009;53:3236-9.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 3236-3239
-
-
Schaadt, R.1
Sweeney, D.2
Shinabarger, D.3
-
10
-
-
84938947288
-
-
(tedizolid phosphate) tablets and for injection [prescribing information]. Lexington, MA: Cubist Pharmaceuticals, Inc; June
-
SIVEXTROR (tedizolid phosphate) tablets and for injection [prescribing information]. Lexington, MA: Cubist Pharmaceuticals, Inc; June 2014.
-
(2014)
-
-
SIVEXTROR1
-
11
-
-
84875996687
-
Potential role of tedizolid phosphate in the treatment of acute bacterial skin infections
-
Urbina O, Ferrandez O, Espona M et al. Potential role of tedizolid phosphate in the treatment of acute bacterial skin infections. Drug Des Devel Ther 2013;7:243-65.
-
(2013)
Drug des Devel Ther
, vol.7
, pp. 243-265
-
-
Urbina, O.1
Ferrandez, O.2
Espona, M.3
-
12
-
-
71249138911
-
Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700)
-
Locke JB, Hilgers M, Shaw KJ. Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700). Antimicrob Agents Chemother 2009;53:5265-74.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 5265-5274
-
-
Locke, J.B.1
Hilgers, M.2
Shaw, K.J.3
-
13
-
-
57049089598
-
In vitro activity of TR-700, the antibacterial moiety of the prodrug TR-701, against linezolidresistant strains
-
Shaw KJ, Poppe S, Schaadt R et al. In vitro activity of TR-700, the antibacterial moiety of the prodrug TR-701, against linezolidresistant strains. Antimicrob Agents Chemother 2008;52:4442-7.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 4442-4447
-
-
Shaw, K.J.1
Poppe, S.2
Schaadt, R.3
-
14
-
-
84892147772
-
Tedizolid for the management of human infections: In vitro characteristics
-
Locke JB, Zurenko GE, Shaw KJ et al. Tedizolid for the management of human infections: in vitro characteristics. Clin Infect Dis 2014;58(S1):S35-42.
-
(2014)
Clin Infect Dis
, vol.58
, Issue.S1
, pp. S35-42
-
-
Locke, J.B.1
Zurenko, G.E.2
Shaw, K.J.3
-
15
-
-
78649668302
-
Structure-activity relationships of diverse oxazolidinones for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations
-
Locke JB, Finn J, Hilgers M et al. Structure-activity relationships of diverse oxazolidinones for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations. Antimicrob Agents Chemother 2010;54:5337-43.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 5337-5343
-
-
Locke, J.B.1
Finn, J.2
Hilgers, M.3
-
16
-
-
84874237535
-
Cfr-mediated linezolid-resistance among methicillin-resistant coagulase-negative staphylococci from infections of humans
-
Cui L, Wang Y, Li Y et al. Cfr-mediated linezolid-resistance among methicillin-resistant coagulase-negative staphylococci from infections of humans. PLoS One 2013;8(2):e57096.
-
(2013)
PLoS One
, vol.8
, Issue.2
-
-
Cui, L.1
Wang, Y.2
Li, Y.3
-
17
-
-
42949115806
-
Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors
-
Smith LK, Mankin AS. Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. Antimicrob Agents Chemother 2008;52:1703-12.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 1703-1712
-
-
Smith, L.K.1
Mankin, A.S.2
-
18
-
-
34250028674
-
Acquisition of a natural resistance gene renders a clinical strain of methicillin-resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid
-
Toh SM, Xiong L, Arias CA et al. Acquisition of a natural resistance gene renders a clinical strain of methicillin-resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid. Mol Microbiol 2007;64:1506-14.
-
(2007)
Mol Microbiol
, vol.64
, pp. 1506-1514
-
-
Toh, S.M.1
Xiong, L.2
Arias, C.A.3
-
19
-
-
77749251875
-
Resistance to linezolid is mediated by the cfr gene in the first report of an outbreak of linezolid-resistant Staphylococcus aureus
-
Morales G, Picazo JJ, Baos E et al. Resistance to linezolid is mediated by the cfr gene in the first report of an outbreak of linezolid-resistant Staphylococcus aureus. Clin Infect Dis 2010;50:821-5.
-
(2010)
Clin Infect Dis
, vol.50
, pp. 821-825
-
-
Morales, G.1
Picazo, J.J.2
Baos, E.3
-
20
-
-
33745599646
-
The cfr rRNA methyltransferase confers resistance to phenicols, lincosamides, oxazolidinones, pleuromutilins, and streptogramin A antibiotics
-
Long KS, Poehlsgaard J, Kehrenberg C et al. The cfr rRNA methyltransferase confers resistance to phenicols, lincosamides, oxazolidinones, pleuromutilins, and streptogramin A antibiotics. Antimicrob Agents Chemother 2006;50:2500-5.
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 2500-2505
-
-
Long, K.S.1
Poehlsgaard, J.2
Kehrenberg, C.3
-
21
-
-
77951234516
-
Comparative in vitro antimicrobial activities of torezolid (TR-700), the active moiety of a new oxazolidinone, torezolid phosphate (TR-701), determination of tentative disk diffusion interpretive criteria, and quality control ranges
-
Brown SD, Traczewski MM. Comparative in vitro antimicrobial activities of torezolid (TR-700), the active moiety of a new oxazolidinone, torezolid phosphate (TR-701), determination of tentative disk diffusion interpretive criteria, and quality control ranges. Antimicrob Agents Chemother 2010;54:2063-9.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2063-2069
-
-
Brown, S.D.1
Traczewski, M.M.2
-
22
-
-
62549099077
-
Activity of oxazolidinone TR-700 against linezolid-susceptible and -resistant staphylococci and enterococci
-
Livermore DM, Mushtaq S, Warner M et al. Activity of oxazolidinone TR-700 against linezolid-susceptible and -resistant staphylococci and enterococci. J Antimicrob Chemother 2009;63:713-5.
-
(2009)
J Antimicrob Chemother
, vol.63
, pp. 713-715
-
-
Livermore, D.M.1
Mushtaq, S.2
Warner, M.3
-
23
-
-
84877844310
-
Activity of tedizolid (TR-700) against well-characterized methicillin-resistant Staphylococcus aureus strains of diverse epidemiological origins
-
Thomson KS, Goering RV. Activity of tedizolid (TR-700) against well-characterized methicillin-resistant Staphylococcus aureus strains of diverse epidemiological origins. Antimicrob Agents Chemother 2013;57:2892-5.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 2892-2895
-
-
Thomson, K.S.1
Goering, R.V.2
-
24
-
-
62549148632
-
TR-700 in vitro activity against and resistance mutation frequencies among Gram-positive pathogens
-
Jones RN, Moet GJ, Sader HS et al. TR-700 in vitro activity against and resistance mutation frequencies among Gram-positive pathogens. J Antimicrob Chemother 2009;63:716-20.
-
(2009)
J Antimicrob Chemother
, vol.63
, pp. 716-720
-
-
Jones, R.N.1
Moet, G.J.2
Sader, H.S.3
-
25
-
-
84865432225
-
In vitro activity and microbiological efficacy of tedizolid (TR-700) against Gram-positive clinical isolates from a phase 2 study of oral tedizolid phosphate (TR- 701) in patients with complicated skin and skin structure infections
-
Prokocimer P, Bien P, DeAnda C et al. In vitro activity and microbiological efficacy of tedizolid (TR-700) against Gram-positive clinical isolates from a phase 2 study of oral tedizolid phosphate (TR- 701) in patients with complicated skin and skin structure infections. Antimicrob Agents Chemother 2012;56:4608-13.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 4608-4613
-
-
Prokocimer, P.1
Bien, P.2
DeAnda, C.3
-
26
-
-
84907977684
-
Single- and multipledose pharmacokinetics and absolute bioavailability of tedizolid
-
Flanagan S, Fang E, Munoz KA et al. Single- and multipledose pharmacokinetics and absolute bioavailability of tedizolid. Pharmacother 2014;34:891-900.
-
(2014)
Pharmacother
, vol.34
, pp. 891-900
-
-
Flanagan, S.1
Fang, E.2
Munoz, K.A.3
-
27
-
-
78751689284
-
Phase 2, randomized, double-blind, dose-ranging study evaluating the safety, tolerability, population pharmacokinetics, and efficacy of oral torezolid phosphate in patients with complicated skin and skin structure infections
-
Prokocimer P, Bien P, Surber J et al. Phase 2, randomized, double-blind, dose-ranging study evaluating the safety, tolerability, population pharmacokinetics, and efficacy of oral torezolid phosphate in patients with complicated skin and skin structure infections. Antimicrob Agents Chemother 2011;55:583-92.
-
(2011)
Antimicrob Agents Chemother
, vol.55
, pp. 583-592
-
-
Prokocimer, P.1
Bien, P.2
Surber, J.3
-
28
-
-
84892166007
-
Pharmacokinetics of tedizolid following oral administration: Single and multiple dose, effect of food, and comparison of two solid forms of the prodrug
-
Flanagan S, Bien PA, Munoz KA et al. Pharmacokinetics of tedizolid following oral administration: single and multiple dose, effect of food, and comparison of two solid forms of the prodrug. Pharmacother 2014;34:240-50.
-
(2014)
Pharmacother
, vol.34
, pp. 240-250
-
-
Flanagan, S.1
Bien, P.A.2
Munoz, K.A.3
-
29
-
-
84904216511
-
Absorption, distribution, metabolism, and excretion of the novel antibacterial prodrug tedizolid phosphate
-
Ong V, Flanagan S, Fang E et al. Absorption, distribution, metabolism, and excretion of the novel antibacterial prodrug tedizolid phosphate. Drug Metab Dispos 2014;42:1275-84.
-
(2014)
Drug Metab Dispos
, vol.42
, pp. 1275-1284
-
-
Ong, V.1
Flanagan, S.2
Fang, E.3
-
30
-
-
84908266611
-
Tedizolid population pharmacokinetics, exposure response, and target attainment
-
Flanagan S, Passarell J, Lu Q et al. Tedizolid population pharmacokinetics, exposure response, and target attainment. Antimicrob Agents Chemother 2014;58:6462-70.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 6462-6470
-
-
Flanagan, S.1
Passarell, J.2
Lu, Q.3
-
31
-
-
84908297834
-
Pharmacokinetics of tedizolid in subjects with renal or hepatic impairment
-
Flanagan S, Minassian SL, Morris D et al. Pharmacokinetics of tedizolid in subjects with renal or hepatic impairment. Antimicrob Agents Chemother 2014;58:6471-6.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 6471-6476
-
-
Flanagan, S.1
Minassian, S.L.2
Morris, D.3
-
32
-
-
84873642637
-
Tedizolid phosphate vs linezolid for treatment of acute bacterial skin and skin structure infections: The ESTABLISH-1 randomized trial
-
Prokocimer P, De Anda C, Fang E et al. Tedizolid phosphate vs linezolid for treatment of acute bacterial skin and skin structure infections: the ESTABLISH-1 randomized trial. JAMA 2013;309:559-69.
-
(2013)
JAMA
, vol.309
, pp. 559-569
-
-
Prokocimer, P.1
De Anda, C.2
Fang, E.3
-
33
-
-
84904718296
-
Tedizolid for 6 days versus linezolid for 10 days for acute bacterial skin and skin-structure infections (ESTABLISH-2): A randomised, double-blind, phase 3, non-inferiority trial
-
Moran GJ, Fang E, Corey GR et al. Tedizolid for 6 days versus linezolid for 10 days for acute bacterial skin and skin-structure infections (ESTABLISH-2): a randomised, double-blind, phase 3, non-inferiority trial. Lancet Infect Dis 2014;14:696-705.
-
(2014)
Lancet Infect Dis
, vol.14
, pp. 696-705
-
-
Moran, G.J.1
Fang, E.2
Corey, G.R.3
-
34
-
-
84912083877
-
Platelet profile in patients with acute bacterial skin and skin structure infections receiving tedizolid or linezolid: Findings from the phase 3 ESTABLISH clinical trials
-
Lodise TP, Fang E, Minassian SL et al. Platelet profile in patients with acute bacterial skin and skin structure infections receiving tedizolid or linezolid: findings from the phase 3 ESTABLISH clinical trials. Antimicrob Agents Chemother 2014;58:7198-204.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 7198-7204
-
-
Lodise, T.P.1
Fang, E.2
Minassian, S.L.3
-
35
-
-
84920142409
-
Nonclinical and pharmacokinetic assessments to evaluate the potential of tedizolid and linezolid to affect mitochondrial function
-
Flanagan S, McKee EE, Das D et al. Nonclinical and pharmacokinetic assessments to evaluate the potential of tedizolid and linezolid to affect mitochondrial function. Antimicrob Agents Chemother 2015;59:178-85.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 178-185
-
-
Flanagan, S.1
McKee, E.E.2
Das, D.3
-
36
-
-
84879009223
-
In vitro, in vivo, and clinical studies of tedizolid to assess the potential for peripheral or central monoamine oxidase interactions
-
Flanagan S, Bartizal K, Minassian SL et al. In vitro, in vivo, and clinical studies of tedizolid to assess the potential for peripheral or central monoamine oxidase interactions. Antimicrob Agents Chemother 2013;57:3060-6.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 3060-3066
-
-
Flanagan, S.1
Bartizal, K.2
Minassian, S.L.3
-
37
-
-
84906095081
-
Two new drugs for skin and skin structure infections
-
Two new drugs for skin and skin structure infections. Med Lett Drugs Ther 2014;56(1449):73-5.
-
(2014)
Med Lett Drugs Ther
, vol.56
, Issue.1449
, pp. 73-75
-
-
-
38
-
-
84903947423
-
Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America
-
Stevens DL, Bisno AL, Chambers HF et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis 2014;59:e10-52.
-
(2014)
Clin Infect Dis
, vol.59
, pp. e10-52
-
-
Stevens, D.L.1
Bisno, A.L.2
Chambers, H.F.3
-
39
-
-
79951844269
-
Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children
-
Liu C, Bayer A, Cosgrove SE et al; Infectious Diseases Society of America. Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin Infect Dis 2011;52:e18-55.
-
(2011)
Clin Infect Dis
, vol.52
, pp. e18-55
-
-
Infectious Diseases Society of America1
Liu, C.2
Bayer, A.3
Cosgrove, S.E.4
|