Discovery of Bivalent Kinase Inhibitors via Enzyme-Templated Fragment Elaboration

ACS Medicinal Chemistry Letters

Volumn 6, Issue 8, 2015, Pages 898-901

  Kwarcinski, Frank E ^a   Steffey, Michael E ^a   Fox, Christel C ^a   Soellner, Matthew B ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

enzyme templated; Kinase; selectivity

Indexed keywords

ACRYLAMIDE DERIVATIVE; CYSTEINE; ELECTROPHILE; PHOSPHOTRANSFERASE INHIBITOR; THIOL;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; ENANTIOMER; MOLECULAR WEIGHT; ONCOGENE SRC; PRIORITY JOURNAL;

EID: 84938913947     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/acsmedchemlett.5b00167     Document Type: Article

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