Inhibitory effect of genistein on PLC/PRF5 hepatocellular carcinoma cell line

International Journal of Preventive Medicine

Volumn 2015-june, Issue , 2015, Pages

  Dastjerdi, Mehdi Nikbakht ^a   Kavoosi, Fraidoon ^a   Valiani, Ali ^a   Esfandiari, Ebrahim ^a   Sanaei, Masume ^b   Sobhanian, Saeed ^b   Hakemi, Mazdak Ganjalikhani ^a   Mobarakian, Maryam ^c  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b JAHROM UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c LORESTAN UNIVERSITY   (Iran)

Author keywords

Apoptosis; Genistein; Hepatocellular carcinoma; Proliferation

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; GENISTEIN;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER INHIBITION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; FLOW CYTOMETRY; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; IC50;

EID: 84938867806     PISSN: 20087802     EISSN: 20088213     Source Type: Journal    
DOI: 10.4103/2008-7802.158914     Document Type: Article

References (56)

1. Motola-Kuba D, Zamora-Valdes D, Uribe M, Mendez-Sanchez N. Hepatocellular carcinoma. An overview. Ann Hepatol 2006;5:16-24.
2. El-Serag HB, Rudolph KL. Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis. Gastroenterology 2007;132:2557-76.
3. Poustchi H, Sepanlou S, Esmaili S, Mehrabi N, Ansarymoghadam A. Hepatocellular carcinoma in the world and the Middle East. Middle East J Dig Dis 2010;2:31-41.
4. Venook AP, Papandreou C, Furuse J, de Guevara LL. The incidence and epidemiology of hepatocellular carcinoma: A global and regional perspective. Oncologist 2010;15 Suppl 4:5-13.
5. Silva MF, Sherman M. Criteria for liver transplantation for HCC: What should the limits be? J Hepatol 2011;55:1137-47.
6. Calvis D, Evert M, Dombrowski F. Review article pathogenetic and prognostic significants of interactication of RASSF proteins in human hepatocellular carcinoma. Mol Biol Int 2012;5:1-9.
7. Cabibbo G, Craxi A. Epidemoilogy, risk factors and surveillance of hepatocellular carcinoma. Mol Biol Int 2012;5:1-9.
8. Altekruse SF, McGlynn KA, Reichman ME. Hepatocellular carcinoma incidence, mortality, and survival trends in the United States from 1975 to 2005. J Clin Oncol 2009;27:1485-91.
9. Gomaa AI, Khan SA, Toledano MB, Waked I, Taylor-Robinson SD. Hepatocellular carcinoma: Epidemiology, risk factors and pathogenesis. World J Gastroenterol 2008;14:4300-8.
10. Jelic S, Sotiropoulos GC, ESMO Guidelines Working Group. Hepatocellular carcinoma: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol 2010;21 Suppl 5:v59-64.
11. Franceschi S, Raza SA. Epidemiology and prevention of hepatocellular carcinoma. Cancer Lett 2009;286:5-8.
12. Alam S, Satpathy P, Thosar A. Plants and its parts as a source of anticancer compound: A review. Int Res J Pharm 2014;5:244-50.
13. Lee JY, Kim HS, Song YS. Genistein as a potential anticancer agent against ovarian cancer. J Tradit Complement Med 2012;2:96-104.
14. Sarkar FH, Li Y, Wang Z, Padhye S. Lesson learned from nature for the development of novel anti-cancer agents: Implication of isoflavone, curcumin, and their synthetic analogs. Curr Pharm Des 2010;16:1801-12.
15. Wiseman M. The Second World Cancer Research Fund/American Institute for Cancer Research Expert Report. Food, nutrition, physical activity, and the prevention of cancer: A global perspective. Proc Nutr Soc 2008;67:253-6.
16. Smith-Warner SA, Spiegelman D, Yaun SS, Albanes D, Beeson WL, van den Brandt PA, et al. Fruits, vegetables and lung cancer: A pooled analysis of cohort studies. Int J Cancer 2003;107:1001-11.
17. Kuno T, Tsukamoto T, Hara A, Tanaka T. Cancer chemoprevention through the induction of apoptosis by natural compounds. J Biophys Chem 2012;3:156-73.
18. Pratheeshkumar P, Sreekala C, Zhang Z, Budhraja A, Ding S, Son YO, et al. Cancer prevention with promising natural products: Mechanisms of action and molecular targets. Anticancer Agents Med Chem 2012;12:1159-84.
19. Abdolmohammadi MH, Fouladdel SH, Shafiee A, Amin G. Ghaffari SM, Azizi E. Anticancer effects and cell cycle analysis on human breast cancer T47D cells treated with extracts of Astrodaucus persicus (Boiss) Drude in comparison to doxorubicin. DARU Journal of Pharmaceutical Sciences 2008;16:112-9.
20. Ramos S. Effects of dietary flavonoids on apoptotic pathways related to cancer chemoprevention. J Nutr Biochem 2007;18:427-42.
21. Ong CS, Tran E, Nguyen TT, Ong CK, Lee SK, Lee JJ, et al. Quercetin-induced growth inhibition and cell death in nasopharyngeal carcinoma cells are associated with increase in bad and hypophosphorylated retinoblastoma expressions. Oncol Rep 2004;11:727-33.
22. Yin F, Giuliano AE, Law RE, Van Herle AJ. Apigenin inhibits growth and induces G2/M arrest by modulating cyclin-CDK regulators and ERK MAP kinase activation in breast carcinoma cells. Anticancer Res 2001;21:413-20.
23. Wang IK, Lin-Shiau SY, Lin JK. Induction of apoptosis by apigenin and related flavonoids through cytochrome c release and activation of caspase-9 and caspase-3 in leukaemia HL-60 cells. Eur J Cancer 1999;35:1517-25.
24. Alexandrakis MG, Kyriakou DS, Kempuraj D, Huang M, Boucher W, Seretakis D, et al. The isoflavone genistein inhibits proliferation and increases histamine content in human leukemic mast cells. Allergy Asthma Proc 2003;24:373-7.
25. Traganos F, Ardelt B, Halko N, Bruno S, Darzynkiewicz Z. Effects of genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells. Cancer Res 1992;52:6200-8.
26. Griffiths K, Hungin APS, De Meester F, Singh RB, Juneja LR. Nutrition and cancer: Dr. Douglas Wilson - Honoured. Open Nutraceuticals J 2013;6:76-83.
27. Adlercreutz H, Fotsis T, Heikkinen R, Dwyer JT, Woods M, Goldin BR et al. Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian women and in women with breast cancer. Lancet 1982;2:1295-9.
28. Adlercreutz H. Diet and cancer: Possible explanations for the higher risk of cancer in the poor. Gastroenterology 1984;86:761-6.
29. Davis JN, Singh B, Bhuiyan M, Sarkar FH. Genistein-induced upregulation of p21WAF1, downregulation of cyclin B, and induction of apoptosis in prostate cancer cells. Nutr Cancer 1998;32:123-31.
30. Lian F, Bhuiyan M, Li YW, Wall N, Kraut M, Sarkar FH. Genistein-induced G2-M arrest, p21WAF1 upregulation, and apoptosis in a non-small-cell lung cancer cell line. Nutr Cancer 1998;31:184-91.
31. Zhou JR, Gugger ET, Tanaka T, Guo Y, Blackburn GL, Clinton SK. Soybean phytochemicals inhibit the growth of transplantable human prostate carcinoma and tumor angiogenesis in mice. J Nutr 1999;129:1628-35.
32. Lee SA, Shu XO, Li H, Yang G, Cai H, Wen W, et al. Adolescent and adult soy food intake and breast cancer risk: Results from the Shanghai Women's Health Study. Am J Clin Nutr 2009;89:1920-6.
33. Kim MK, Kim JH, Nam SJ, Ryu S, Kong G. Dietary intake of soy protein and tofu in association with breast cancer risk based on a case-control study. Nutr Cancer 2008;60:568-76.
34. Hirose K, Imaeda N, Tokudome Y, Goto C, Wakai K, Matsuo K, et al. Soybean products and reduction of breast cancer risk: A case-control study in Japan. Br J Cancer 2005;93:15-22.
35. Sonoda T, Nagata Y, Mori M, Miyanaga N, Takashima N, Okumura K, et al. A case-control study of diet and prostate cancer in Japan: Possible protective effect of traditional Japanese diet. Cancer Sci 2004;95:238-42.
36. Suthar AC, Banavalikar MM, Biyani MK. Pharmacological activities of genistein, an isoflavone from soy (Glycine max): part I - anti-cancer activity. Indian J Exp Biol 2001;39:511-9.
37. Elmore S. Apoptosis: A review of programmed cell death. Toxicol Pathol 2007;35:495-516.
38. Nishino H, Tokuda H, Satomi Y, Masuda M, Onozuka M, Yamaguchi S, et al. Cancer chemoprevention by phytochemicals and their related compounds. Asian Pac J Cancer Prev 2000;1:49-55.
39. Nigam N, George J, Srivastava S, Roy P, Bhui K, Singh M, et al. Induction of apoptosis by [6]-gingerol associated with the modulation of p53 and involvement of mitochondrial signaling pathway in B[a] P-induced mouse skin tumorigenesis. Cancer Chemother Pharmacol 2010;65:687-96.
40. Powis G, Hill SR, Frew TJ, Sherrill KW. Inhibitors of phospholipid intracellular signaling as antiproliferative agents. Med Res Rev 1995;15:121-38.
41. Gu Y, Zhu CF, Iwamoto H, Chen JS. Genistein inhibits invasive potential of human hepatocellular carcinoma by altering cell cycle, apoptosis, and angiogenesis. World J Gastroenterol 2005;11:6512-7.
42. Song RX, Santen RJ. Apoptotic action of estrogen. Apoptosis 2003;8:55-60.
43. Deroo BJ, Korach KS. Estrogen receptors and human disease. J Clin Invest 2006;116:561-70.
44. Chang KL, Cheng HL, Huang LW, Hsieh BS, Hu YC, Chih TT, et al. Combined effects of terazosin and genistein on a metastatic, hormone-independent human prostate cancer cell line. Cancer Lett 2009;276:14-20.
45. Fioravanti L, Cappelletti V, Miodini P, Ronchi E, Brivio M, Di Fronzo G. Genistein in the control of breast cancer cell growth: Insights into the mechanism of action in vitro. Cancer Lett 1998;130:143-52.
46. Lee J, Ju J, Park S, Hong SJ, Yoon S. Inhibition of IGF-1 signaling by genistein: Modulation of E-cadherin expression and downregulation of s-catenin signaling in hormone refractory PC-3 prostate cancer cells. Nutr Cancer 2012;64:153-62.
47. Seo YJ, Kim BS, Chun SY, Park YK, Kang KS, Kwon TG. Apoptotic effects of genistein, biochanin-A and apigenin on LNCaP and PC-3 cells by p21 through transcriptional inhibition of polo-like kinase-1. J Korean Med Sci 2011;26:1489-94.
48. Abdalla A, Darwish AS, Elbanhawy R, Ghouraba A, Shehata S. Hepatocellular carcinoma: An overview of disease epidemiology and risk factors. Intern J Allied Med Sci Clin Res 2014;2:205-9.
49. Chen AC, Donovan SM. Genistein at a concentration present in soy infant formula inhibits 50 caco-2BBe cell proliferation by causing G2/M cell cycle arrest1. Biochemical and molecular actions of nutrients. J Nutr 2004;134:1303-8.
50. Kim EJ, Shin HK, Park JH. Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: A possible mechanism of the growth inhibitory effect of Genistein. J Med Food 2005;8:431-8.
51. Kim EJ, Shin HK, Park JH. Genistein inhibits insulin-like growth factor-I receptor signaling in HT-29 human colon cancer cells: A possible mechanism of the growth inhibitory effect of Genistein. J Med Food 2005;8:431-8.
52. Meloche S, Pouysségur J. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 2007;26:3227-39.
53. Park JH, Oh EJ, Choi YH, Kang CD, Kang HS, Kim DK, et al. Synergistic effects of dexamethasone and genistein on the expression of Cdk inhibitor p21WAF1/CIP1 in human hepatocellular and colorectal carcinoma cells. Int J Oncol 2001;18:997-1002.
54. Kwon Y. Effect of soy isoflavones on the growth of human breast tumors: Findings from preclinical studies. Food Sci Nutr 2014;2:613-22.
55. Gwin J, Drews N, Ali S, Stamschror J, Sorenson M, Rajah TT. Effect of genistein on p90RSK phosphorylation and cell proliferation in T47D breast cancer cells. Anticancer Res 2011;31:209-14.
56. Squadrito F, Altavilla D, Squadrito G, Saitta A, Cucinotta D, Minutoli L, et al. Genistein supplementation and estrogen replacement therapy improve endothelial dysfunction induced by ovariectomy in rats. Cardiovasc Res 2000;45:454-62.