Design, characterization and in vitro evaluation of novel shell crosslinked poly(butylene adipate)-co-N-succinyl chitosan nanogels containing loteprednol etabonate: A new system for therapeutic effect enhancement via controlled drug delivery

European Journal of Medicinal Chemistry

Volumn 102, Issue , 2015, Pages 132-142

  Nasr, Farzaneh Hashemi ^a   Khoee, Sepideh ^a  

^a UNIVERSITY OF TEHRAN   (Iran)

Author keywords

Loteprednol etabonate; N succinyl chitosan; Ocular therapy; Poly(butylene adipate); Shell crosslinked nanogel

Indexed keywords

CHITOSAN NANOPARTICLE; CYANAMIDE; LOTEPREDNOL ETABONATE; POLY(BUTYLENE ADIPATE); POLY(BUTYLENE ADIPATE) CO N SUCCINYL CHITOSAN NANOGEL; UNCLASSIFIED DRUG; BUTANEDIOL; BUTYLENE GLYCOL ADIPIC ACID POLYESTER; CHITOSAN; CROSS LINKING REAGENT; MACROGOL DERIVATIVE; N-SUCCINYL-CHITOSAN; NANOGEL; POLYETHYLENEIMINE; POLYMER;

ANIMAL CELL; ARTICLE; BIOCOMPATIBILITY; BIODEGRADABILITY; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG FORMULATION; FEMALE; GEL PERMEATION CHROMATOGRAPHY; IN VITRO STUDY; INFRARED SPECTROSCOPY; MOLECULAR WEIGHT; MUCOADHESION; NANOEMULSION; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PROTON NUCLEAR MAGNETIC RESONANCE; THERAPY EFFECT; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL; ANIMAL; CELL CULTURE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; CORNEA EPITHELIUM; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; RABBIT; STRUCTURE ACTIVITY RELATION;

ANIMALS; BUTYLENE GLYCOLS; CELL SURVIVAL; CELLS, CULTURED; CHITOSAN; CROSS-LINKING REAGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; DRUG DESIGN; EPITHELIUM, CORNEAL; FEMALE; LOTEPREDNOL ETABONATE; MOLECULAR STRUCTURE; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; POLYMERS; RABBITS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84938865449     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2015.07.045     Document Type: Article

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