메뉴 건너뛰기




Volumn 10, Issue 4, 1998, Pages 329-339

Loteprednol etabonate: Clinical potential in the management of ocular inflammation

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; DELTA1 CORTIENIC ACID; DELTA1 CORTIENIC ACID ETABONATE; DRUG METABOLITE; LOTEPREDNOL ETABONATE; PLACEBO; PREDNISOLONE ACETATE; UNCLASSIFIED DRUG;

EID: 0031795568     PISSN: 11738804     EISSN: None     Source Type: Journal    
DOI: 10.2165/00063030-199810040-00007     Document Type: Review
Times cited : (35)

References (33)
  • 1
    • 7844225208 scopus 로고    scopus 로고
    • Development of soft drugs for ophthalmic use
    • Reddy IK, editor. Lancaster (PA): Technomic Publishing Company, Inc.
    • Howes JF. Development of soft drugs for ophthalmic use. In: Reddy IK, editor. Ocular therapeutics and drug delivery: a multidisciplinary approach. Lancaster (PA): Technomic Publishing Company, Inc., 1996: 363-74
    • (1996) Ocular Therapeutics and Drug Delivery: A Multidisciplinary Approach , pp. 363-374
    • Howes, J.F.1
  • 2
    • 0027745484 scopus 로고
    • Design of novel soft corticosteroids
    • Bodor N. Design of novel soft corticosteroids. Curr Probl Dermatol 1993; 21: 11-9
    • (1993) Curr Probl Dermatol , vol.21 , pp. 11-19
    • Bodor, N.1
  • 3
    • 0028230775 scopus 로고
    • Designing safer ophthalmic drugs by soft drug approaches
    • Bodor N. Designing safer ophthalmic drugs by soft drug approaches. J Ocul Pharmacol 1994; 10(1): 3-15
    • (1994) J Ocul Pharmacol , vol.10 , Issue.1 , pp. 3-15
    • Bodor, N.1
  • 4
    • 0020341606 scopus 로고
    • Subcellular distribution of esterases in the bovine eye
    • Lee HL, Iimoto DS, Takemoto KA. Subcellular distribution of esterases in the bovine eye. Curr Eye Res 1982/1983; 2(12): 869-76
    • (1982) Curr Eye Res , vol.2 , Issue.12 , pp. 869-876
    • Lee, H.L.1    Iimoto, D.S.2    Takemoto, K.A.3
  • 5
    • 0022285021 scopus 로고
    • Effect of substrate concentration, product concentration, and peptides on the in vitro hydrolysis of model ester prodrugs by corneal esterases
    • Lee VHL, Smith RE. Effect of substrate concentration, product concentration, and peptides on the in vitro hydrolysis of model ester prodrugs by corneal esterases. J Ocul Pharmacol 1985; 1 (3): 269-78
    • (1985) J Ocul Pharmacol , vol.1 , Issue.3 , pp. 269-278
    • Lee, V.H.L.1    Smith, R.E.2
  • 6
    • 0026100181 scopus 로고
    • Soft drugs - 10. Blanching activity and receptor binding affinity of a new type of glucocorticoid: Loteprednol etabonate
    • Feb
    • Druzgala P, Hochhaus G, Bodor N. Soft drugs - 10. Blanching activity and receptor binding affinity of a new type of glucocorticoid: loteprednol etabonate. J Steroid Biochem Mol Biol 1991 Feb; 38: 149-54
    • (1991) J Steroid Biochem Mol Biol , vol.38 , pp. 149-154
    • Druzgala, P.1    Hochhaus, G.2    Bodor, N.3
  • 7
    • 0031700446 scopus 로고    scopus 로고
    • The conjunctival provocation test model of ocular allergy: Utility for assessment of an ocular corticosteroid, loteprednol etabonate
    • In press
    • Abelson M, Howes J, George M. The conjunctival provocation test model of ocular allergy: utility for assessment of an ocular corticosteroid, loteprednol etabonate. J Ocul Pharmacol Ther 1998 (In press)
    • (1998) J Ocul Pharmacol Ther
    • Abelson, M.1    Howes, J.2    George, M.3
  • 8
    • 0029885907 scopus 로고    scopus 로고
    • Permeability of a soft steroid, loteprednol etabonate, through an excised rabbit cornea
    • Reddy IK, Khan MA, Wu W-M, et al. Permeability of a soft steroid, loteprednol etabonate, through an excised rabbit cornea. J Ocul Pharmacol Ther 1996; 12 (2): 159-67
    • (1996) J Ocul Pharmacol Ther , vol.12 , Issue.2 , pp. 159-167
    • Reddy, I.K.1    Khan, M.A.2    Wu, W.-M.3
  • 9
    • 0025991941 scopus 로고
    • Ocular absorption and distribution of loteprednol etabonate, a soft steroid, in rabbit eyes
    • Oct
    • Druzgala P, Wu W-M, Bodor N. Ocular absorption and distribution of loteprednol etabonate, a soft steroid, in rabbit eyes. Curr Eye Res 1991 Oct; 10: 933-7
    • (1991) Curr Eye Res , vol.10 , pp. 933-937
    • Druzgala, P.1    Wu, W.-M.2    Bodor, N.3
  • 10
    • 0031966882 scopus 로고    scopus 로고
    • Failure to detect systemic levels, and effects of loteprednol etabonate and its metabolite. PJ-91, following chronic ocular administration
    • Howes J, Novack GD. Failure to detect systemic levels, and effects of loteprednol etabonate and its metabolite. PJ-91, following chronic ocular administration. J Ocul Pharmacol Ther 1997; 14 (2): 153-8
    • (1997) J Ocul Pharmacol Ther , vol.14 , Issue.2 , pp. 153-158
    • Howes, J.1    Novack, G.D.2
  • 11
    • 0027053957 scopus 로고
    • Pharmacokinetic characterization and tissue distribution of the new glucocorticoid soft drug loteprednol etabonate in rats and dogs
    • Dec
    • Hochhaus G, Chien L-S, Ratka A, et al. Pharmacokinetic characterization and tissue distribution of the new glucocorticoid soft drug loteprednol etabonate in rats and dogs. J Pharm Sci 1992 Dec; 81: 1210-5
    • (1992) J Pharm Sci , vol.81 , pp. 1210-1215
    • Hochhaus, G.1    Chien, L.-S.2    Ratka, A.3
  • 12
    • 0028998734 scopus 로고
    • Soft drugs 19. Pharmacokinetics, metabolism and excretion of a novel soft corticosteroid, loteprednol etabonate, in rats
    • Jun
    • Bodor N, Wu W-M, Murakami T, et al. Soft drugs 19. Pharmacokinetics, metabolism and excretion of a novel soft corticosteroid, loteprednol etabonate, in rats. Pharm Res 1995 Jun; 12: 875-9
    • (1995) Pharm Res , vol.12 , pp. 875-879
    • Bodor, N.1    Wu, W.-M.2    Murakami, T.3
  • 13
    • 0026788230 scopus 로고
    • Metabolism, distribution, and transdermal permeation of a soft corticosteroid, loteprednol etabonate
    • Oct
    • Bodor N, Loftsson T, Wu W-m. Metabolism, distribution, and transdermal permeation of a soft corticosteroid, loteprednol etabonate. Pharm Res 1992 Oct; 9: 1275-8
    • (1992) Pharm Res , vol.9 , pp. 1275-1278
    • Bodor, N.1    Loftsson, T.2    Wu, W.-M.3
  • 14
    • 7844238680 scopus 로고
    • Pharmacokinetics, metabolism and excretion of a soft corticosteroid, loteprednol etabonate
    • Oct
    • Wu W-M, Murakami T, Angel S, et al. Pharmacokinetics, metabolism and excretion of a soft corticosteroid, loteprednol etabonate [abstract]. Pharm Res 1992 Oct; 9 (Suppl): S295
    • (1992) Pharm Res , vol.9 , Issue.SUPPL.
    • Wu, W.-M.1    Murakami, T.2    Angel, S.3
  • 15
    • 2642621998 scopus 로고
    • Metabolism and excretion of loteprednol etabonate, a soft corticosteroid, in rats
    • Oct
    • Wu W-M, Bodor N. Metabolism and excretion of loteprednol etabonate, a soft corticosteroid, in rats [abstract]. Pharm Res 1994 Oct; 11 Suppl.: 364
    • (1994) Pharm Res , vol.11 , Issue.SUPPL. , pp. 364
    • Wu, W.-M.1    Bodor, N.2
  • 16
    • 0031791136 scopus 로고    scopus 로고
    • A double-masked, placebo-controlled evaluation of 0.5% loteprednol etabonate in the treatment of post-operative inflammation
    • In press
    • Stewart R, Horwitz B, Howes J, et al. A double-masked, placebo-controlled evaluation of 0.5% loteprednol etabonate in the treatment of post-operative inflammation. J Cataract Refract Surg 1998 (In press)
    • (1998) J Cataract Refract Surg
    • Stewart, R.1    Horwitz, B.2    Howes, J.3
  • 17
    • 0343640813 scopus 로고    scopus 로고
    • A double-masked, placebo-controlled evaluation of 0.5% loteprednol etabonate in the treatment of post-operative inflammation
    • In press
    • The Loteprednol Etabonate Post-operative Inflammation Study Group 2. A double-masked, placebo-controlled evaluation of 0.5% loteprednol etabonate in the treatment of post-operative inflammation. Ophthalmology 1998 (In press)
    • (1998) Ophthalmology
  • 18
    • 0030963092 scopus 로고    scopus 로고
    • A controlled evaluation of the efficacy and safety of loteprednol etabonate in the prophylactic treatment of seasonal allergic conjunctivitis
    • Jun
    • Dell SJ, Shulman DG, Lowry GM, et al. A controlled evaluation of the efficacy and safety of loteprednol etabonate in the prophylactic treatment of seasonal allergic conjunctivitis. Am J Ophthalmol 1997 Jun; 123: 791-7
    • (1997) Am J Ophthalmol , vol.123 , pp. 791-797
    • Dell, S.J.1    Shulman, D.G.2    Lowry, G.M.3
  • 19
    • 0031722635 scopus 로고    scopus 로고
    • A randomized, double-masked, placebo-controlled parallel study of loteprednol etabonate 0.2% in patients with seasonal allergic conjunctivitis
    • Aug
    • Dell SJ, Lowry G, Northcutt JA, et al. A randomized, double-masked, placebo-controlled parallel study of loteprednol etabonate 0.2% in patients with seasonal allergic conjunctivitis. J Allergy Clin Immunol 1998 Aug; 102 (2): 251-5
    • (1998) J Allergy Clin Immunol , vol.102 , Issue.2 , pp. 251-255
    • Dell, S.J.1    Lowry, G.2    Northcutt, J.A.3
  • 20
    • 7844240548 scopus 로고    scopus 로고
    • A randomized, double-masked, placebo-controlled parallel study of loteprednol etabonate 0.2% in patients with seasonal allergic conjunctivitis
    • In press
    • Shulman DG, Lothringer HL, Rubin JM, et al. A randomized, double-masked, placebo-controlled parallel study of loteprednol etabonate 0.2% in patients with seasonal allergic conjunctivitis. Ophthalmology 1998 (In press)
    • (1998) Ophthalmology
    • Shulman, D.G.1    Lothringer, H.L.2    Rubin, J.M.3
  • 21
    • 0027311235 scopus 로고
    • Safety and efficacy of loteprednol etabonate for treatment of papillae in contact lens-associated giant papillary conjunctivitis
    • Apr
    • Bartlett JD, Howes JF, Ghormley NR, et al. Safety and efficacy of loteprednol etabonate for treatment of papillae in contact lens-associated giant papillary conjunctivitis. Curr Eye Res 1993 Apr; 12: 313-21
    • (1993) Curr Eye Res , vol.12 , pp. 313-321
    • Bartlett, J.D.1    Howes, J.F.2    Ghormley, N.R.3
  • 22
    • 0030999849 scopus 로고    scopus 로고
    • A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis
    • Apr
    • Friedlaender MH, Howes J. A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis. Am J Ophthalmol 1997 Apr; 123: 455-64
    • (1997) Am J Ophthalmol , vol.123 , pp. 455-464
    • Friedlaender, M.H.1    Howes, J.2
  • 23
    • 0031021022 scopus 로고    scopus 로고
    • A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis
    • Jan
    • Asbell P, Howes J. A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis. CLAO J 1997 Jan; 23: 31-6
    • (1997) CLAO J , vol.23 , pp. 31-36
    • Asbell, P.1    Howes, J.2
  • 24
    • 0029739497 scopus 로고    scopus 로고
    • Corticosteroid therapy of eye disease: Fifty years later
    • Raizman M. Corticosteroid therapy of eye disease: Fifty years later. Arch Ophthalmol 1996; 114 (8): 1000-1
    • (1996) Arch Ophthalmol , vol.114 , Issue.8 , pp. 1000-1001
    • Raizman, M.1
  • 25
    • 0032467764 scopus 로고    scopus 로고
    • Change in intraocular pressure during chronic use of loteprednol etabonate
    • In press
    • Novack GD, Howes J, Crockett RS, et al. Change in intraocular pressure during chronic use of loteprednol etabonate. J Glaucoma 1998. In press
    • (1998) J Glaucoma
    • Novack, G.D.1    Howes, J.2    Crockett, R.S.3
  • 26
    • 0027159211 scopus 로고
    • Intraocular pressure response to loteprednol etabonate in known steroid responders
    • Summer
    • Bartlett JD, Horwitz B, Laibovitz R, et al. Intraocular pressure response to loteprednol etabonate in known steroid responders. J Ocul Pharmacol 1993 Summer; 9: 157-65
    • (1993) J Ocul Pharmacol , vol.9 , pp. 157-165
    • Bartlett, J.D.1    Horwitz, B.2    Laibovitz, R.3
  • 30
    • 17344386189 scopus 로고
    • Giant papillary conjunctivitis
    • Allansmith MR. Giant papillary conjunctivitis. J Am Optom Assoc 1990; 61 (6) Suppl.: S42-46
    • (1990) J Am Optom Assoc , vol.61 , Issue.6 SUPPL.
    • Allansmith, M.R.1
  • 32
    • 0022655979 scopus 로고
    • Ocular allergy and mast cell stabilizers
    • Jan/Feb
    • Allansmith MR, Ross RN. Ocular allergy and mast cell stabilizers. Surv Ophthalmol 1986 Jan/Feb; 30 (4): 229-44
    • (1986) Surv Ophthalmol , vol.30 , Issue.4 , pp. 229-244
    • Allansmith, M.R.1    Ross, R.N.2
  • 33
    • 0025988435 scopus 로고
    • Therapeutic dilemmas in external ocular diseases
    • Oct
    • Asbell PA, Torres MA. Therapeutic dilemmas in external ocular diseases. Drugs 1991 Oct; 42: 606-15
    • (1991) Drugs , vol.42 , pp. 606-615
    • Asbell, P.A.1    Torres, M.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.