Development of a thermally responsive nanogel based on chitosan-Poly(N- Isopropylacrylamide-co-Acrylamide) for paclitaxel delivery

Journal of Pharmaceutical Sciences

Volumn 103, Issue 7, 2014, Pages 2012-2021

  Wang, Yajing ^a   Xu, Hongjiang ^b   Wang, Jiu ^c   Ge, Liang ^c   Zhu, Jiabi ^c  

^a GUANGXI UNIVERSITY   (China)

^b Drug Research Institute   (China)

^c CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

cancer; chitosan; hydrogel; polymeric drug carrier; responsive delivery system

Indexed keywords

6 METHYLCOUMARIN; CHITOSAN; PACLITAXEL; POLY(N ISOPROPYLACRYLAMIDE); ACRYLIC ACID RESIN; ANTINEOPLASTIC AGENT; CHITOSAN-POLY(N-ISOPROPYLACRYLAMIDE-CO-ACRYLAMIDE); DRUG CARRIER; GEL; NANOMATERIAL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG RELEASE; ENDOCYTOSIS; FEMALE; HT 29 CELL LINE; HUMAN; HUMAN CELL; HYPERTHERMIC THERAPY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NANOENCAPSULATION; NANOGEL; NONHUMAN; NUDE MOUSE; PARTICLE SIZE; PHASE TRANSITION; POLYMERIZATION; RADICAL REACTION; RAT; TUMOR XENOGRAFT; ANALOGS AND DERIVATIVES; ANIMAL; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; DRUG SCREENING; ERYTHROCYTE; GEL; HEMOLYSIS; SPRAGUE DAWLEY RAT; TRANSITION TEMPERATURE;

ACRYLIC RESINS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL SURVIVAL; CHITOSAN; DRUG CARRIERS; DRUG LIBERATION; ENDOCYTOSIS; ERYTHROCYTES; GELS; HEMOLYSIS; HT29 CELLS; HUMANS; MICE; NANOSTRUCTURES; PACLITAXEL; RATS, SPRAGUE-DAWLEY; TRANSITION TEMPERATURE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84902973553     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23995     Document Type: Article

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